[Novel Research Progress of the Recombinant Vaccine for MERS-CoV].
Identifieur interne : 001065 ( PubMed/Curation ); précédent : 001064; suivant : 001066[Novel Research Progress of the Recombinant Vaccine for MERS-CoV].
Auteurs : Huizhen Hu ; Yuqing ShenSource :
- Bing du xue bao = Chinese journal of virology [ 1000-8721 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (immunologie), Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Humains, Infections à coronavirus (), Infections à coronavirus (immunologie), Infections à coronavirus (virologie), Vaccins antiviraux (administration et posologie), Vaccins antiviraux (génétique), Vaccins antiviraux (immunologie), Vaccins synthétiques (administration et posologie), Vaccins synthétiques (génétique), Vaccins synthétiques (immunologie).
- MESH :
- administration et posologie : Vaccins antiviraux, Vaccins synthétiques.
- génétique : Coronavirus du syndrome respiratoire du Moyen-Orient, Vaccins antiviraux, Vaccins synthétiques.
- immunologie : Anticorps antiviraux, Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus, Vaccins antiviraux, Vaccins synthétiques.
- virologie : Infections à coronavirus.
- Animaux, Humains, Infections à coronavirus.
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (immunology), Coronavirus Infections (immunology), Coronavirus Infections (prevention & control), Coronavirus Infections (virology), Humans, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (immunology), Vaccines, Synthetic (administration & dosage), Vaccines, Synthetic (genetics), Vaccines, Synthetic (immunology), Viral Vaccines (administration & dosage), Viral Vaccines (genetics), Viral Vaccines (immunology).
- MESH :
- chemical , administration & dosage : Vaccines, Synthetic, Viral Vaccines.
- chemical , genetics : Vaccines, Synthetic, Viral Vaccines.
- chemical , immunology : Antibodies, Viral, Vaccines, Synthetic, Viral Vaccines.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- immunology : Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- prevention & control : Coronavirus Infections.
- virology : Coronavirus Infections.
- Animals, Humans.
Abstract
Respiratory syndrome coronavirus in the Middle East (MERS-Co V) has caused wide attention since it was discovered, and the design of effective vaccines for MERS-Co V becomes a hot area at present. Therefore, this review is aimed at novel research progress of the recombinant vaccine for MERS-Co V, including selection and improvement of animal model for vaccine test,construction and optimization of recombinant subunit vaccine, attempts at recombinant live vector vaccine based on varies of vectors, as well as the advantages of pseudovirus. In conclusion, we make a summary about the novel research progress of the recombinant vaccine for MERS-Co V and a promising prospect of its development in terms of both safety and effectiveness verification in the future will be demonstrated.
PubMed: 29995374
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xml:lang="en">Respiratory syndrome coronavirus in the Middle East (MERS-Co V) has caused wide attention since it was discovered, and the design of effective vaccines for MERS-Co V becomes a hot area at present. Therefore, this review is aimed at novel research progress of the recombinant vaccine for MERS-Co V, including selection and improvement of animal model for vaccine test,construction and optimization of recombinant subunit vaccine, attempts at recombinant live vector vaccine based on varies of vectors, as well as the advantages of pseudovirus. In conclusion, we make a summary about the novel research progress of the recombinant vaccine for MERS-Co V and a promising prospect of its development in terms of both safety and effectiveness verification in the future will be demonstrated.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29995374</PMID><DateCompleted><Year>2018</Year><Month>07</Month><Day>31</Day></DateCompleted><DateRevised><Year>2018</Year><Month>07</Month><Day>31</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1000-8721</ISSN><JournalIssue CitedMedium="Print"><Volume>32</Volume><Issue>4</Issue><PubDate><Year>2016</Year><Month>07</Month></PubDate></JournalIssue><Title>Bing du xue bao = Chinese journal of virology</Title><ISOAbbreviation>Bing Du Xue Bao</ISOAbbreviation></Journal><ArticleTitle>[Novel Research Progress of the Recombinant Vaccine for MERS-CoV].</ArticleTitle><Pagination><MedlinePgn>495-500</MedlinePgn></Pagination><Abstract><AbstractText>Respiratory syndrome coronavirus in the Middle East (MERS-Co V) has caused wide attention since it was discovered, and the design of effective vaccines for MERS-Co V becomes a hot area at present. 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