MersV1, PubMed, Curation, bibRecord, 000B13

Nosocomial amplification of MERS-coronavirus in South Korea, 2015.

Identifieur interne : 000B13 ( PubMed/Curation ); précédent : 000B12; suivant : 000B14

Nosocomial amplification of MERS-coronavirus in South Korea, 2015.

Auteurs : Maimuna S. Majumder [États-Unis] ; John S. Brownstein [États-Unis] ; Stan N. Finkelstein [États-Unis] ; Richard C. Larson [États-Unis] ; Lydia Bourouiba [États-Unis]

Source :

Transactions of the Royal Society of Tropical Medicine and Hygiene [ 1878-3503 ] ; 2017.

RBID : pubmed:29044371

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Co-infection (transmission), Co-infection (virologie), Co-infection (étiologie), Coronavirus du syndrome respiratoire du Moyen-Orient, Environnement, Femelle, Flambées de maladies, Humains, Hôpitaux, Infection croisée (virologie), Infections à coronavirus (mortalité), Infections à coronavirus (transmission), Infections à coronavirus (virologie), Infections à coronavirus (étiologie), Mâle, République de Corée (épidémiologie), Sujet âgé, Ventilation.
MESH :
- mortalité : Infections à coronavirus.
- virologie : Co-infection, Infection croisée, Infections à coronavirus.
- épidémiologie : Co-infection, Infections à coronavirus, République de Corée.
- étiologie : Co-infection, Infections à coronavirus.
- Adulte, Adulte d'âge moyen, Coronavirus du syndrome respiratoire du Moyen-Orient, Environnement, Femelle, Flambées de maladies, Humains, Hôpitaux, Mâle, Sujet âgé, Ventilation.

English descriptors

KwdEn :
- Adult, Aged, Coinfection (etiology), Coinfection (transmission), Coinfection (virology), Coronavirus Infections (etiology), Coronavirus Infections (mortality), Coronavirus Infections (transmission), Coronavirus Infections (virology), Cross Infection (virology), Disease Outbreaks, Environment, Female, Hospitals, Humans, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus, Republic of Korea (epidemiology), Ventilation.
MESH :
- epidemiology : Republic of Korea.
- etiology : Coinfection, Coronavirus Infections.
- mortality : Coronavirus Infections.
- transmission : Coinfection, Coronavirus Infections.
- virology : Coinfection, Coronavirus Infections, Cross Infection.
- Adult, Aged, Disease Outbreaks, Environment, Female, Hospitals, Humans, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus, Ventilation.

Abstract

Nosocomial amplification resulted in nearly 200 cases of Middle East respiratory syndrome (MERS) during the 2015 South Korean MERS-coronavirus outbreak. It remains unclear whether certain types of cases were more likely to cause secondary infections than others, and if so, why.

DOI: 10.1093/trstmh/trx046
PubMed: 29044371

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Nosocomial amplification resulted in nearly 200 cases of Middle East respiratory syndrome (MERS) during the 2015 South Korean MERS-coronavirus outbreak. It remains unclear whether certain types of cases were more likely to cause secondary infections than others, and if so, why.</div>
</front>
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<DateCompleted><Year>2018</Year>
<Month>06</Month>
<Day>11</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>03</Day>
</DateRevised>
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<JournalIssue CitedMedium="Internet"><Volume>111</Volume>
<Issue>6</Issue>
<PubDate><Year>2017</Year>
<Month>06</Month>
<Day>01</Day>
</PubDate>
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<Title>Transactions of the Royal Society of Tropical Medicine and Hygiene</Title>
<ISOAbbreviation>Trans. R. Soc. Trop. Med. Hyg.</ISOAbbreviation>
</Journal>
<ArticleTitle>Nosocomial amplification of MERS-coronavirus in South Korea, 2015.</ArticleTitle>
<Pagination><MedlinePgn>261-269</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1093/trstmh/trx046</ELocationID>
<Abstract><AbstractText Label="Background">Nosocomial amplification resulted in nearly 200 cases of Middle East respiratory syndrome (MERS) during the 2015 South Korean MERS-coronavirus outbreak. It remains unclear whether certain types of cases were more likely to cause secondary infections than others, and if so, why.</AbstractText>
<AbstractText Label="Methods">Publicly available demographic and transmission network data for all cases were collected from the Ministry of Health and Welfare. Statistical analyses were conducted to determine the relationship between demographic characteristics and the likelihood of human-to-human transmission. Findings from the statistical analyses were used to inform a hypothesis-directed literature review, through which mechanistic explanations for nosocomial amplification were developed.</AbstractText>
<AbstractText Label="Results">Cases that failed to recover from MERS were more likely to cause secondary infections than those that did. Increased probability of direct, human-to-human transmission due to clinical manifestations associated with death, as well as indirect transmission via environmental contamination (e.g., fomites and indoor ventilation systems), may serve as mechanistic explanations for nosocomial amplification of MERS-coronavirus in South Korea.</AbstractText>
<AbstractText Label="Conclusions">In addition to closely monitoring contacts of MERS cases that fail to recover during future nosocomial outbreaks, potential fomites with which they may have had contact should be sanitized. Furthermore, indoor ventilation systems that minimize recirculation of pathogen-bearing droplets should be implemented whenever possible.</AbstractText>
<CopyrightInformation>© The Author 2017. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Majumder</LastName>
<ForeName>Maimuna S</ForeName>
<Initials>MS</Initials>
<AffiliationInfo><Affiliation>Institute for Data, Systems, and Society, Massachusetts Institute of Technology, Cambridge, MA, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Computational Epidemiology Group, Boston Children's Hospital, Boston, MA, USA.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Brownstein</LastName>
<ForeName>John S</ForeName>
<Initials>JS</Initials>
<AffiliationInfo><Affiliation>Computational Epidemiology Group, Boston Children's Hospital, Boston, MA, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Pediatrics, Harvard Medical School, Boston, MA, USA.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Finkelstein</LastName>
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<Initials>SN</Initials>
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</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Health Care Policy, Harvard Medical School, Boston, MA, USA.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Larson</LastName>
<ForeName>Richard C</ForeName>
<Initials>RC</Initials>
<AffiliationInfo><Affiliation>Institute for Data, Systems, and Society, Massachusetts Institute of Technology, Cambridge, MA, USA.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Bourouiba</LastName>
<ForeName>Lydia</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>The Fluid Dynamics of Disease Transmission Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.</Affiliation>
</AffiliationInfo>
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<Acronym>LM</Acronym>
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Nosocomial amplification of MERS-coronavirus in South Korea, 2015.

Nosocomial amplification of MERS-coronavirus in South Korea, 2015.

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