Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism.
Identifieur interne : 000666 ( PubMed/Curation ); précédent : 000665; suivant : 000667Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism.
Auteurs : Craig Schindewolf [États-Unis] ; Vineet D. Menachery [États-Unis]Source :
- Viruses [ 1999-4915 ] ; 2019.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (immunologie), Anticorps neutralisants (immunologie), Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Glycoprotéine de spicule des coronavirus (génétique), Glycoprotéine de spicule des coronavirus (immunologie), Humains, Infections à coronavirus (), Infections à coronavirus (immunologie), Modèles animaux de maladie humaine, Souris, Vaccination, Vaccins antiviraux (immunologie), Vaccins atténués (immunologie).
- MESH :
- génétique : Coronavirus du syndrome respiratoire du Moyen-Orient, Glycoprotéine de spicule des coronavirus.
- immunologie : Anticorps antiviraux, Anticorps neutralisants, Coronavirus du syndrome respiratoire du Moyen-Orient, Glycoprotéine de spicule des coronavirus, Infections à coronavirus, Vaccins antiviraux, Vaccins atténués.
- Animaux, Humains, Infections à coronavirus, Modèles animaux de maladie humaine, Souris, Vaccination.
English descriptors
- KwdEn :
- Animals, Antibodies, Neutralizing (immunology), Antibodies, Viral (immunology), Coronavirus Infections (immunology), Coronavirus Infections (prevention & control), Disease Models, Animal, Humans, Mice, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (immunology), Spike Glycoprotein, Coronavirus (genetics), Spike Glycoprotein, Coronavirus (immunology), Vaccination, Vaccines, Attenuated (immunology), Viral Vaccines (immunology).
- MESH :
- chemical , genetics : Spike Glycoprotein, Coronavirus.
- chemical , immunology : Antibodies, Neutralizing, Antibodies, Viral, Spike Glycoprotein, Coronavirus, Vaccines, Attenuated, Viral Vaccines.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- immunology : Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- prevention & control : Coronavirus Infections.
- Animals, Disease Models, Animal, Humans, Mice, Vaccination.
Abstract
Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines.
DOI: 10.3390/v11010074
PubMed: 30658390
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Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30658390</PMID><DateCompleted><Year>2019</Year><Month>06</Month><Day>06</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>09</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1999-4915</ISSN><JournalIssue CitedMedium="Internet"><Volume>11</Volume><Issue>1</Issue><PubDate><Year>2019</Year><Month>01</Month><Day>17</Day></PubDate></JournalIssue><Title>Viruses</Title><ISOAbbreviation>Viruses</ISOAbbreviation></Journal><ArticleTitle>Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E74</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/v11010074</ELocationID><Abstract><AbstractText>Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. 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