Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility.
Identifieur interne : 001B40 ( PubMed/Corpus ); précédent : 001B39; suivant : 001B41Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility.
Auteurs : Simon Cauchemez ; Christophe Fraser ; Maria D. Van Kerkhove ; Christl A. Donnelly ; Steven Riley ; Andrew Rambaut ; Vincent Enouf ; Sylvie Van Der Werf ; Neil M. FergusonSource :
- The Lancet. Infectious diseases [ 1474-4457 ] ; 2014.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Basic Reproduction Number, Child, Child, Preschool, Cluster Analysis, Coronavirus (classification), Coronavirus (genetics), Coronavirus (isolation & purification), Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Coronavirus Infections (virology), Epidemics, Epidemiological Monitoring, Female, Humans, Male, Middle Aged, Middle East (epidemiology), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (transmission), Respiratory Tract Infections (virology), Risk Assessment, Survival Analysis, Young Adult.
- MESH :
- geographic , epidemiology : Middle East.
- classification : Coronavirus.
- epidemiology : Coronavirus Infections, Respiratory Tract Infections.
- genetics : Coronavirus.
- isolation & purification : Coronavirus.
- transmission : Coronavirus Infections, Respiratory Tract Infections.
- virology : Coronavirus Infections, Respiratory Tract Infections.
- Adolescent, Adult, Aged, Aged, 80 and over, Basic Reproduction Number, Child, Child, Preschool, Cluster Analysis, Epidemics, Epidemiological Monitoring, Female, Humans, Male, Middle Aged, Risk Assessment, Survival Analysis, Young Adult.
Abstract
The novel Middle East respiratory syndrome coronavirus (MERS-CoV) had, as of Aug 8, 2013, caused 111 virologically confirmed or probable human cases of infection worldwide. We analysed epidemiological and genetic data to assess the extent of human infection, the performance of case detection, and the transmission potential of MERS-CoV with and without control measures.
DOI: 10.1016/S1473-3099(13)70304-9
PubMed: 24239323
Links to Exploration step
pubmed:24239323Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility.</title><author><name sortKey="Cauchemez, Simon" sort="Cauchemez, Simon" uniqKey="Cauchemez S" first="Simon" last="Cauchemez">Simon Cauchemez</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Fraser, Christophe" sort="Fraser, Christophe" uniqKey="Fraser C" first="Christophe" last="Fraser">Christophe Fraser</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Donnelly, Christl A" sort="Donnelly, Christl A" uniqKey="Donnelly C" first="Christl A" last="Donnelly">Christl A. Donnelly</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Riley, Steven" sort="Riley, Steven" uniqKey="Riley S" first="Steven" last="Riley">Steven Riley</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Rambaut, Andrew" sort="Rambaut, Andrew" uniqKey="Rambaut A" first="Andrew" last="Rambaut">Andrew Rambaut</name><affiliation><nlm:affiliation>Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Enouf, Vincent" sort="Enouf, Vincent" uniqKey="Enouf V" first="Vincent" last="Enouf">Vincent Enouf</name><affiliation><nlm:affiliation>Institut Pasteur, Unit of Molecular Genetics of RNA Viruses, UMR3569 CNRS, Université Paris Diderot Sorbonne Paris Cité, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Werf, Sylvie" sort="Van Der Werf, Sylvie" uniqKey="Van Der Werf S" first="Sylvie" last="Van Der Werf">Sylvie Van Der Werf</name><affiliation><nlm:affiliation>Institut Pasteur, Unit of Molecular Genetics of RNA Viruses, UMR3569 CNRS, Université Paris Diderot Sorbonne Paris Cité, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Ferguson, Neil M" sort="Ferguson, Neil M" uniqKey="Ferguson N" first="Neil M" last="Ferguson">Neil M. Ferguson</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK. Electronic address: neil.ferguson@imperial.ac.uk.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24239323</idno><idno type="pmid">24239323</idno><idno type="doi">10.1016/S1473-3099(13)70304-9</idno><idno type="wicri:Area/PubMed/Corpus">001B40</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001B40</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility.</title><author><name sortKey="Cauchemez, Simon" sort="Cauchemez, Simon" uniqKey="Cauchemez S" first="Simon" last="Cauchemez">Simon Cauchemez</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Fraser, Christophe" sort="Fraser, Christophe" uniqKey="Fraser C" first="Christophe" last="Fraser">Christophe Fraser</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Donnelly, Christl A" sort="Donnelly, Christl A" uniqKey="Donnelly C" first="Christl A" last="Donnelly">Christl A. Donnelly</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Riley, Steven" sort="Riley, Steven" uniqKey="Riley S" first="Steven" last="Riley">Steven Riley</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Rambaut, Andrew" sort="Rambaut, Andrew" uniqKey="Rambaut A" first="Andrew" last="Rambaut">Andrew Rambaut</name><affiliation><nlm:affiliation>Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Enouf, Vincent" sort="Enouf, Vincent" uniqKey="Enouf V" first="Vincent" last="Enouf">Vincent Enouf</name><affiliation><nlm:affiliation>Institut Pasteur, Unit of Molecular Genetics of RNA Viruses, UMR3569 CNRS, Université Paris Diderot Sorbonne Paris Cité, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Werf, Sylvie" sort="Van Der Werf, Sylvie" uniqKey="Van Der Werf S" first="Sylvie" last="Van Der Werf">Sylvie Van Der Werf</name><affiliation><nlm:affiliation>Institut Pasteur, Unit of Molecular Genetics of RNA Viruses, UMR3569 CNRS, Université Paris Diderot Sorbonne Paris Cité, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Ferguson, Neil M" sort="Ferguson, Neil M" uniqKey="Ferguson N" first="Neil M" last="Ferguson">Neil M. Ferguson</name><affiliation><nlm:affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK. Electronic address: neil.ferguson@imperial.ac.uk.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The Lancet. Infectious diseases</title><idno type="eISSN">1474-4457</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Basic Reproduction Number</term><term>Child</term><term>Child, Preschool</term><term>Cluster Analysis</term><term>Coronavirus (classification)</term><term>Coronavirus (genetics)</term><term>Coronavirus (isolation & purification)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (transmission)</term><term>Coronavirus Infections (virology)</term><term>Epidemics</term><term>Epidemiological Monitoring</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Middle East (epidemiology)</term><term>Respiratory Tract Infections (epidemiology)</term><term>Respiratory Tract Infections (transmission)</term><term>Respiratory Tract Infections (virology)</term><term>Risk Assessment</term><term>Survival Analysis</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Middle East</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Basic Reproduction Number</term><term>Child</term><term>Child, Preschool</term><term>Cluster Analysis</term><term>Epidemics</term><term>Epidemiological Monitoring</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Risk Assessment</term><term>Survival Analysis</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The novel Middle East respiratory syndrome coronavirus (MERS-CoV) had, as of Aug 8, 2013, caused 111 virologically confirmed or probable human cases of infection worldwide. We analysed epidemiological and genetic data to assess the extent of human infection, the performance of case detection, and the transmission potential of MERS-CoV with and without control measures.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24239323</PMID><DateCompleted><Year>2014</Year><Month>02</Month><Day>24</Day></DateCompleted><DateRevised><Year>2019</Year><Month>10</Month><Day>08</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1474-4457</ISSN><JournalIssue CitedMedium="Internet"><Volume>14</Volume><Issue>1</Issue><PubDate><Year>2014</Year><Month>Jan</Month></PubDate></JournalIssue><Title>The Lancet. Infectious diseases</Title><ISOAbbreviation>Lancet Infect Dis</ISOAbbreviation></Journal><ArticleTitle>Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility.</ArticleTitle><Pagination><MedlinePgn>50-56</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1473-3099(13)70304-9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/S1473-3099(13)70304-9</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The novel Middle East respiratory syndrome coronavirus (MERS-CoV) had, as of Aug 8, 2013, caused 111 virologically confirmed or probable human cases of infection worldwide. We analysed epidemiological and genetic data to assess the extent of human infection, the performance of case detection, and the transmission potential of MERS-CoV with and without control measures.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We assembled a comprehensive database of all confirmed and probable cases from public sources and estimated the incubation period and generation time from case cluster data. Using data of numbers of visitors to the Middle East and their duration of stay, we estimated the number of symptomatic cases in the Middle East. We did independent analyses, looking at the growth in incident clusters, the growth in viral population, the reproduction number of cluster index cases, and cluster sizes to characterise the dynamical properties of the epidemic and the transmission scenario.</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">The estimated number of symptomatic cases up to Aug 8, 2013, is 940 (95% CI 290-2200), indicating that at least 62% of human symptomatic cases have not been detected. We find that the case-fatality ratio of primary cases detected via routine surveillance (74%; 95% CI 49-91) is biased upwards because of detection bias; the case-fatality ratio of secondary cases was 20% (7-42). Detection of milder cases (or clinical management) seemed to have improved in recent months. Analysis of human clusters indicated that chains of transmission were not self-sustaining when infection control was implemented, but that R in the absence of controls was in the range 0·8-1·3. Three independent data sources provide evidence that R cannot be much above 1, with an upper bound of 1·2-1·5.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">By showing that a slowly growing epidemic is underway either in human beings or in an animal reservoir, quantification of uncertainty in transmissibility estimates, and provision of the first estimates of the scale of the epidemic and extent of case detection biases, we provide valuable information for more informed risk assessment.</AbstractText><AbstractText Label="FUNDING" NlmCategory="BACKGROUND">Medical Research Council, Bill & Melinda Gates Foundation, EU FP7, and National Institute of General Medical Sciences.</AbstractText><CopyrightInformation>Copyright © 2014 Cauchemez et al. Open Access article distributed under the terms of CC BY. Published by Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Cauchemez</LastName><ForeName>Simon</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fraser</LastName><ForeName>Christophe</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Van Kerkhove</LastName><ForeName>Maria D</ForeName><Initials>MD</Initials><AffiliationInfo><Affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Donnelly</LastName><ForeName>Christl A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Riley</LastName><ForeName>Steven</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rambaut</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Enouf</LastName><ForeName>Vincent</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Institut Pasteur, Unit of Molecular Genetics of RNA Viruses, UMR3569 CNRS, Université Paris Diderot Sorbonne Paris Cité, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Werf</LastName><ForeName>Sylvie</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institut Pasteur, Unit of Molecular Genetics of RNA Viruses, UMR3569 CNRS, Université Paris Diderot Sorbonne Paris Cité, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferguson</LastName><ForeName>Neil M</ForeName><Initials>NM</Initials><AffiliationInfo><Affiliation>MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK. Electronic address: neil.ferguson@imperial.ac.uk.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>095831</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>G0800596</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/J008761/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/K010174/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>11</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Lancet Infect Dis</MedlineTA><NlmUniqueID>101130150</NlmUniqueID><ISSNLinking>1473-3099</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Lancet Infect Dis. 2014 Jan;14(1):6-7</RefSource><PMID Version="1">24239325</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D050936" MajorTopicYN="N">Basic Reproduction Number</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016000" MajorTopicYN="N">Cluster Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017934" MajorTopicYN="N">Coronavirus</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000635" MajorTopicYN="Y">transmission</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058872" MajorTopicYN="Y">Epidemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062665" MajorTopicYN="N">Epidemiological Monitoring</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008877" MajorTopicYN="N" Type="Geographic">Middle East</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012141" MajorTopicYN="N">Respiratory Tract Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000635" MajorTopicYN="Y">transmission</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018570" MajorTopicYN="N">Risk Assessment</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016019" MajorTopicYN="N">Survival Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>11</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>11</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>2</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24239323</ArticleId><ArticleId IdType="pii">S1473-3099(13)70304-9</ArticleId><ArticleId IdType="doi">10.1016/S1473-3099(13)70304-9</ArticleId><ArticleId IdType="pmc">PMC3895322</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Am J Epidemiol. 2005 Sep 1;162(5):479-86</Citation><ArticleIdList><ArticleId IdType="pubmed">16076827</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2004 Sep;10(9):1653-6</Citation><ArticleIdList><ArticleId IdType="pubmed">15498170</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2009 Jun 19;324(5934):1557-61</Citation><ArticleIdList><ArticleId IdType="pubmed">19433588</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2012 Nov 8;367(19):1814-20</Citation><ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId></ArticleIdList></Reference><Reference><Citation>MBio. 2012;3(6). pii: e00473-12. doi: 10.1128/mBio.00473-12</Citation><ArticleIdList><ArticleId IdType="pubmed">23170002</ArticleId></ArticleIdList></Reference><Reference><Citation>Euro Surveill. 2013;18(24). pii: 20503</Citation><ArticleIdList><ArticleId IdType="pubmed">23787162</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2013 Jun 27;368(26):2487-94</Citation><ArticleIdList><ArticleId IdType="pubmed">23718156</ArticleId></ArticleIdList></Reference><Reference><Citation>East Mediterr Health J. 2013;19 Suppl 1:S12-8</Citation><ArticleIdList><ArticleId IdType="pubmed">23888790</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2003 Dec 11;426(6967):658-61</Citation><ArticleIdList><ArticleId IdType="pubmed">14668863</ArticleId></ArticleIdList></Reference><Reference><Citation>Epidemiol Infect. 2006 Apr;134(2):211-21</Citation><ArticleIdList><ArticleId IdType="pubmed">16490123</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Epidemiol. 2004 Sep 15;160(6):509-16</Citation><ArticleIdList><ArticleId IdType="pubmed">15353409</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Infect Dis. 2013 Sep;17(9):e668-72</Citation><ArticleIdList><ArticleId IdType="pubmed">23916548</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2013 Aug 24;382(9893):694-9</Citation><ArticleIdList><ArticleId IdType="pubmed">23831141</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2013 Oct;13(10):859-66</Citation><ArticleIdList><ArticleId IdType="pubmed">23933067</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2013 Dec 14;382(9909):1993-2002</Citation><ArticleIdList><ArticleId IdType="pubmed">24055451</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 Jun 20;300(5627):1966-70</Citation><ArticleIdList><ArticleId IdType="pubmed">12766207</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2013 Aug 1;369(5):407-16</Citation><ArticleIdList><ArticleId IdType="pubmed">23782161</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6146-51</Citation><ArticleIdList><ArticleId IdType="pubmed">15071187</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001B40 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 001B40 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:24239323
|texte= Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:24239323" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |