Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity.
Identifieur interne : 001932 ( PubMed/Corpus ); précédent : 001931; suivant : 001933Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity.
Auteurs : M G Hemida ; R A Perera ; R A Al Jassim ; G. Kayali ; L Y Siu ; P. Wang ; K W Chu ; S. Perlman ; M A Ali ; A. Alnaeem ; Y. Guan ; L L Poon ; L. Saif ; M. PeirisSource :
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [ 1560-7917 ] ; 2014.
English descriptors
- KwdEn :
- Animals, Antibodies, Neutralizing (blood), Antibodies, Viral (blood), Australia (epidemiology), Camelus (blood), Cattle (blood), Coronavirus (immunology), Coronavirus (isolation & purification), Coronavirus Infections (blood), Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Humans, Immunoglobulin G (blood), Neutralization Tests (methods), Prevalence, Respiratory Tract Infections (blood), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (virology), Saudi Arabia (epidemiology), Seroepidemiologic Studies.
- MESH :
- chemical , blood : Antibodies, Neutralizing, Antibodies, Viral, Immunoglobulin G.
- blood : Camelus, Cattle, Coronavirus Infections, Respiratory Tract Infections.
- epidemiology : Australia, Coronavirus Infections, Respiratory Tract Infections, Saudi Arabia.
- immunology : Coronavirus.
- isolation & purification : Coronavirus.
- methods : Neutralization Tests.
- virology : Coronavirus Infections, Respiratory Tract Infections.
- Animals, Humans, Prevalence, Seroepidemiologic Studies.
Abstract
The pseudoparticle virus neutralisation test (ppNT) and a conventional microneutralisation (MN) assay are specific for detecting antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV) when used in seroepidemiological studies in animals. Genetically diverse MERS-CoV appear antigenically similar in MN tests. We confirm that MERS-CoV was circulating in dromedaries in Saudi Arabia in 1993. Preliminary data suggest that feral Australian dromedaries may be free of MERS-CoV but larger confirmatory studies are needed.
DOI: 10.2807/1560-7917.es2014.19.23.20828
PubMed: 24957744
Links to Exploration step
pubmed:24957744Le document en format XML
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<front><div type="abstract" xml:lang="en">The pseudoparticle virus neutralisation test (ppNT) and a conventional microneutralisation (MN) assay are specific for detecting antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV) when used in seroepidemiological studies in animals. Genetically diverse MERS-CoV appear antigenically similar in MN tests. We confirm that MERS-CoV was circulating in dromedaries in Saudi Arabia in 1993. Preliminary data suggest that feral Australian dromedaries may be free of MERS-CoV but larger confirmatory studies are needed.</div>
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