MersV1, PubMed, Corpus, bibRecord, 001033

Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015.

Identifieur interne : 001033 ( PubMed/Corpus ); précédent : 001032; suivant : 001034

Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015.

Auteurs : Sun Hee Park ; Woo Joo Kim ; Jin-Hong Yoo ; Jung-Hyun Choi

Source :

Infection & chemotherapy [ 2093-2340 ] ; 2016.

RBID : pubmed:27433381

Abstract

Epidemiologic parameters are important in planning infection control policies during the outbreak of emerging infections. Korea experienced an outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infection in 2015, which was characterized by superspreading events in healthcare settings. We aimed to estimate the epidemiologic parameters over time during the outbreak to assess the effectiveness of countermeasures.

DOI: 10.3947/ic.2016.48.2.108
PubMed: 27433381

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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015.</title>
<author><name sortKey="Park, Sun Hee" sort="Park, Sun Hee" uniqKey="Park S" first="Sun Hee" last="Park">Sun Hee Park</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kim, Woo Joo" sort="Kim, Woo Joo" uniqKey="Kim W" first="Woo Joo" last="Kim">Woo Joo Kim</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine, Seoul, Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Yoo, Jin Hong" sort="Yoo, Jin Hong" uniqKey="Yoo J" first="Jin-Hong" last="Yoo">Jin-Hong Yoo</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Choi, Jung Hyun" sort="Choi, Jung Hyun" uniqKey="Choi J" first="Jung-Hyun" last="Choi">Jung-Hyun Choi</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</nlm:affiliation>
</affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015.</title>
<author><name sortKey="Park, Sun Hee" sort="Park, Sun Hee" uniqKey="Park S" first="Sun Hee" last="Park">Sun Hee Park</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kim, Woo Joo" sort="Kim, Woo Joo" uniqKey="Kim W" first="Woo Joo" last="Kim">Woo Joo Kim</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine, Seoul, Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Yoo, Jin Hong" sort="Yoo, Jin Hong" uniqKey="Yoo J" first="Jin-Hong" last="Yoo">Jin-Hong Yoo</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Choi, Jung Hyun" sort="Choi, Jung Hyun" uniqKey="Choi J" first="Jung-Hyun" last="Choi">Jung-Hyun Choi</name>
<affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</nlm:affiliation>
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<series><title level="j">Infection & chemotherapy</title>
<idno type="ISSN">2093-2340</idno>
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<front><div type="abstract" xml:lang="en">Epidemiologic parameters are important in planning infection control policies during the outbreak of emerging infections. Korea experienced an outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infection in 2015, which was characterized by superspreading events in healthcare settings. We aimed to estimate the epidemiologic parameters over time during the outbreak to assess the effectiveness of countermeasures.</div>
</front>
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<pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">27433381</PMID>
<DateCompleted><Year>2016</Year>
<Month>07</Month>
<Day>19</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">2093-2340</ISSN>
<JournalIssue CitedMedium="Print"><Volume>48</Volume>
<Issue>2</Issue>
<PubDate><Year>2016</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Infection & chemotherapy</Title>
<ISOAbbreviation>Infect Chemother</ISOAbbreviation>
</Journal>
<ArticleTitle>Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015.</ArticleTitle>
<Pagination><MedlinePgn>108-17</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.3947/ic.2016.48.2.108</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Epidemiologic parameters are important in planning infection control policies during the outbreak of emerging infections. Korea experienced an outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infection in 2015, which was characterized by superspreading events in healthcare settings. We aimed to estimate the epidemiologic parameters over time during the outbreak to assess the effectiveness of countermeasures.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Publicly available data pertaining to the MERS outbreak in Korea were collected. We estimated the incubation periods of 162 cases whose sources of exposure were identified and the temporal trend was evaluated. Factors influencing incubation duration were analyzed. The generational reproduction number (Rg ) and case reproduction number (R(c) ) were estimated over time.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The estimated median incubation period was 7.4 days (95% CI, 6.9-8.0). Median incubation periods tended to be longer over time as the disease generation progressed: 6.16 days (95% CI, 5.38-6.97), 7.68 days (95% CI, 7.04-8.44), and 7.95 days (95% CI, 6.25-9.88) in the first, second, and third generations, respectively. The number of days of illness in the source cases at the time of exposure inversely correlated with the incubation periods in the receiving cases (HR 0.91 [95% CI, 0.84-0.99] per one illness day increase; P=0.026). This relationship was consistent (HR 0.83 [95% CI, 0.74-0.93] per one illness day increase) in the multivariable analysis incorporating clinical characteristics, the order of generation, and a link to superspreaders. Because the third generation cases were exposed to their source cases in the early stage (median one day) compared to the second generation cases (median 6 days), the temporal trend of incubation periods appears to be influenced by early isolation of symptomatic cases and reduction of potential exposure to source cases in the later stage. Rg declined rapidly from 28 to 0.23 in two generations. R(c) dropped below the epidemic threshold at one on May 31, 2015, which approximately coincided with the initiation of the stringent countermeasures.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Despite the initial delay, the stringent countermeasures targeted towards second generation cases appeared to effectively contain the MERS outbreak in Korea as suggested by the decline of R(c) shortly after implementation. Except for superspreading events, the transmission potential for MERS-CoV seems to be low. Further research should be focused on characterizing superspreaders in comparison to non-transmitting cases with regard to environmental, behavioral, and virologic and host genetic factors in order to better prepare for future outbreaks of MERS-CoV.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Park</LastName>
<ForeName>Sun Hee</ForeName>
<Initials>SH</Initials>
<Identifier Source="ORCID">0000-0001-5648-9237</Identifier>
<AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kim</LastName>
<ForeName>Woo Joo</ForeName>
<Initials>WJ</Initials>
<Identifier Source="ORCID">0000-0002-4546-3880</Identifier>
<AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine, Seoul, Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yoo</LastName>
<ForeName>Jin-Hong</ForeName>
<Initials>JH</Initials>
<AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Choi</LastName>
<ForeName>Jung-Hyun</ForeName>
<Initials>JH</Initials>
<AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.</Affiliation>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2016</Year>
<Month>06</Month>
<Day>30</Day>
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<MedlineJournalInfo><Country>Korea (South)</Country>
<MedlineTA>Infect Chemother</MedlineTA>
<NlmUniqueID>101531537</NlmUniqueID>
<ISSNLinking>1598-8112</ISSNLinking>
</MedlineJournalInfo>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Countermeasures</Keyword>
<Keyword MajorTopicYN="N">Incubation period</Keyword>
<Keyword MajorTopicYN="N">Korea</Keyword>
<Keyword MajorTopicYN="N">Middle East Respiratory Syndrome</Keyword>
<Keyword MajorTopicYN="N">Reproduction number</Keyword>
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<Month>04</Month>
<Day>23</Day>
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<PubMedPubDate PubStatus="revised"><Year>2016</Year>
<Month>06</Month>
<Day>04</Day>
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<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>06</Month>
<Day>07</Day>
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<ReferenceList><Reference><Citation>Infect Chemother. 2016 Mar;48(1):61-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27104019</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Epidemiol. 2013 Nov 1;178(9):1505-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24043437</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2015 Jun 25;20(25):1-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26132766</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Stat Med. 2009 Sep 30;28(22):2769-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19598148</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Epidemiol. 2004 Sep 15;160(6):509-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15353409</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Themes Epidemiol. 2007 May 11;4:2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17466070</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Med. 2015 Sep 03;13:210</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26336062</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Osong Public Health Res Perspect. 2015 Aug;6(4):269-78</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26473095</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2014 Jan;59(1):4-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24286807</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2014 Jan 18;383(9913):189-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24439726</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2016 Feb 15;62(4):477-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26565003</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2013 Aug 24;382(9893):694-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23831141</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiol Health. 2015 Jul 21;37:e2015033</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26212508</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMJ Open. 2016 Feb 23;6(2):e009936</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26908522</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Chemother. 2015 Dec;47(4):247-51</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26788408</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiol Health. 2015 Sep 17;37:e2015041</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26725225</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiol Health. 2015 Aug 15;37:e2015036</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26493651</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Epidemiol. 2003 Dec 1;158(11):1039-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14630599</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2007 Aug 22;2(8):e758</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17712406</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiol Health. 2015 Sep 16;37:e2015040</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26493654</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiol Health. 2015 Dec 10;:null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26971695</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Korean Med Sci. 2015 Nov;30(11):1701-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26539018</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2015 Jun 25;20(25):7-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26132767</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2005 Nov 17;438(7066):355-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16292310</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

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Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015.

Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015.

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