A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes.
Identifieur interne : 000F04 ( PubMed/Corpus ); précédent : 000F03; suivant : 000F05A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes.
Auteurs : Musa A. Garbati ; Shamsudeen F. Fagbo ; Vicky J. Fang ; Leila Skakni ; Mercy Joseph ; Tariq A. Wani ; Benjamin J. Cowling ; Malik Peiris ; Ahmed HakawiSource :
- PloS one [ 1932-6203 ] ; 2016.
English descriptors
- KwdEn :
- Acute Disease, Adolescent, Adult, Aged, Child, Child, Preschool, Comorbidity, Coronavirus Infections (diagnosis), Coronavirus Infections (therapy), Female, Hospitalization, Humans, Infant, Infant, Newborn, Kaplan-Meier Estimate, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (physiology), Prognosis, Risk Factors, Young Adult.
- MESH :
- diagnosis : Coronavirus Infections.
- physiology : Middle East Respiratory Syndrome Coronavirus.
- therapy : Coronavirus Infections.
- Acute Disease, Adolescent, Adult, Aged, Child, Child, Preschool, Comorbidity, Female, Hospitalization, Humans, Infant, Infant, Newborn, Kaplan-Meier Estimate, Male, Middle Aged, Prognosis, Risk Factors, Young Adult.
Abstract
Middle East Respiratory syndrome (MERS) first emerged in Saudi Arabia in 2012 and remains a global health concern. The objective of this study was to compare the clinical features and risk factors for adverse outcome in patients with RT-PCR confirmed MERS and in those with acute respiratory disease who were MERS-CoV negative, presenting to the King Fahad Medical City (KFMC) in Riyadh between October 2012 and May 2014. The demographics, clinical and laboratory characteristics and clinical outcomes of patients with RT-PCR confirmed MERS-CoV infection was compared with those testing negative MERS-CoV PCR. Health care workers (HCW) with MERS were compared with MERS patients who were not health care workers. One hundred and fifty nine patients were eligible for inclusion. Forty eight tested positive for MERS CoV, 44 (92%) being hospital acquired infections and 23 were HCW. There were 111 MERS-CoV negative patients with acute respiratory illnesses included in this study as "negative controls". Patient with confirmed MERS-CoV infection were not clinically distinguishable from those with negative MERS-CoV RT-PCR results although diarrhoea was commoner in MERS patients. A high level of suspicion in initiating laboratory tests for MERS-CoV is therefore indicated. Variables associated with adverse outcome were older age and diabetes as a co-morbid illness. Interestingly, co-morbid illnesses other than diabetes were not significantly associated with poor outcome. Health care workers with MERS had a markedly better clinical outcome compared to non HCW MERS patients.
DOI: 10.1371/journal.pone.0165978
PubMed: 27812197
Links to Exploration step
pubmed:27812197Le document en format XML
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Fang</name><affiliation><nlm:affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</nlm:affiliation></affiliation></author><author><name sortKey="Skakni, Leila" sort="Skakni, Leila" uniqKey="Skakni L" first="Leila" last="Skakni">Leila Skakni</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Joseph, Mercy" sort="Joseph, Mercy" uniqKey="Joseph M" first="Mercy" last="Joseph">Mercy Joseph</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Wani, Tariq A" sort="Wani, Tariq A" uniqKey="Wani T" first="Tariq A" last="Wani">Tariq A. Wani</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Cowling, Benjamin J" sort="Cowling, Benjamin J" uniqKey="Cowling B" first="Benjamin J" last="Cowling">Benjamin J. Cowling</name><affiliation><nlm:affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</nlm:affiliation></affiliation></author><author><name sortKey="Peiris, Malik" sort="Peiris, Malik" uniqKey="Peiris M" first="Malik" last="Peiris">Malik Peiris</name><affiliation><nlm:affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</nlm:affiliation></affiliation></author><author><name sortKey="Hakawi, Ahmed" sort="Hakawi, Ahmed" uniqKey="Hakawi A" first="Ahmed" last="Hakawi">Ahmed Hakawi</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27812197</idno><idno type="pmid">27812197</idno><idno type="doi">10.1371/journal.pone.0165978</idno><idno type="wicri:Area/PubMed/Corpus">000F04</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000F04</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes.</title><author><name sortKey="Garbati, Musa A" sort="Garbati, Musa A" uniqKey="Garbati M" first="Musa A" last="Garbati">Musa A. Garbati</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Fagbo, Shamsudeen F" sort="Fagbo, Shamsudeen F" uniqKey="Fagbo S" first="Shamsudeen F" last="Fagbo">Shamsudeen F. Fagbo</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Fang, Vicky J" sort="Fang, Vicky J" uniqKey="Fang V" first="Vicky J" last="Fang">Vicky J. Fang</name><affiliation><nlm:affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</nlm:affiliation></affiliation></author><author><name sortKey="Skakni, Leila" sort="Skakni, Leila" uniqKey="Skakni L" first="Leila" last="Skakni">Leila Skakni</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Joseph, Mercy" sort="Joseph, Mercy" uniqKey="Joseph M" first="Mercy" last="Joseph">Mercy Joseph</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Wani, Tariq A" sort="Wani, Tariq A" uniqKey="Wani T" first="Tariq A" last="Wani">Tariq A. Wani</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Cowling, Benjamin J" sort="Cowling, Benjamin J" uniqKey="Cowling B" first="Benjamin J" last="Cowling">Benjamin J. Cowling</name><affiliation><nlm:affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</nlm:affiliation></affiliation></author><author><name sortKey="Peiris, Malik" sort="Peiris, Malik" uniqKey="Peiris M" first="Malik" last="Peiris">Malik Peiris</name><affiliation><nlm:affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</nlm:affiliation></affiliation></author><author><name sortKey="Hakawi, Ahmed" sort="Hakawi, Ahmed" uniqKey="Hakawi A" first="Ahmed" last="Hakawi">Ahmed Hakawi</name><affiliation><nlm:affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute Disease</term><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Child</term><term>Child, Preschool</term><term>Comorbidity</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (therapy)</term><term>Female</term><term>Hospitalization</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Middle East Respiratory Syndrome Coronavirus (physiology)</term><term>Prognosis</term><term>Risk Factors</term><term>Young Adult</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Acute Disease</term><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Child</term><term>Child, Preschool</term><term>Comorbidity</term><term>Female</term><term>Hospitalization</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Prognosis</term><term>Risk Factors</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Middle East Respiratory syndrome (MERS) first emerged in Saudi Arabia in 2012 and remains a global health concern. The objective of this study was to compare the clinical features and risk factors for adverse outcome in patients with RT-PCR confirmed MERS and in those with acute respiratory disease who were MERS-CoV negative, presenting to the King Fahad Medical City (KFMC) in Riyadh between October 2012 and May 2014. The demographics, clinical and laboratory characteristics and clinical outcomes of patients with RT-PCR confirmed MERS-CoV infection was compared with those testing negative MERS-CoV PCR. Health care workers (HCW) with MERS were compared with MERS patients who were not health care workers. One hundred and fifty nine patients were eligible for inclusion. Forty eight tested positive for MERS CoV, 44 (92%) being hospital acquired infections and 23 were HCW. There were 111 MERS-CoV negative patients with acute respiratory illnesses included in this study as "negative controls". Patient with confirmed MERS-CoV infection were not clinically distinguishable from those with negative MERS-CoV RT-PCR results although diarrhoea was commoner in MERS patients. A high level of suspicion in initiating laboratory tests for MERS-CoV is therefore indicated. Variables associated with adverse outcome were older age and diabetes as a co-morbid illness. Interestingly, co-morbid illnesses other than diabetes were not significantly associated with poor outcome. Health care workers with MERS had a markedly better clinical outcome compared to non HCW MERS patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27812197</PMID><DateCompleted><Year>2017</Year><Month>06</Month><Day>28</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN><JournalIssue CitedMedium="Internet"><Volume>11</Volume><Issue>11</Issue><PubDate><Year>2016</Year></PubDate></JournalIssue><Title>PloS one</Title><ISOAbbreviation>PLoS ONE</ISOAbbreviation></Journal><ArticleTitle>A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes.</ArticleTitle><Pagination><MedlinePgn>e0165978</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0165978</ELocationID><Abstract><AbstractText>Middle East Respiratory syndrome (MERS) first emerged in Saudi Arabia in 2012 and remains a global health concern. The objective of this study was to compare the clinical features and risk factors for adverse outcome in patients with RT-PCR confirmed MERS and in those with acute respiratory disease who were MERS-CoV negative, presenting to the King Fahad Medical City (KFMC) in Riyadh between October 2012 and May 2014. The demographics, clinical and laboratory characteristics and clinical outcomes of patients with RT-PCR confirmed MERS-CoV infection was compared with those testing negative MERS-CoV PCR. Health care workers (HCW) with MERS were compared with MERS patients who were not health care workers. One hundred and fifty nine patients were eligible for inclusion. Forty eight tested positive for MERS CoV, 44 (92%) being hospital acquired infections and 23 were HCW. There were 111 MERS-CoV negative patients with acute respiratory illnesses included in this study as "negative controls". Patient with confirmed MERS-CoV infection were not clinically distinguishable from those with negative MERS-CoV RT-PCR results although diarrhoea was commoner in MERS patients. A high level of suspicion in initiating laboratory tests for MERS-CoV is therefore indicated. Variables associated with adverse outcome were older age and diabetes as a co-morbid illness. Interestingly, co-morbid illnesses other than diabetes were not significantly associated with poor outcome. Health care workers with MERS had a markedly better clinical outcome compared to non HCW MERS patients.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Garbati</LastName><ForeName>Musa A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fagbo</LastName><ForeName>Shamsudeen F</ForeName><Initials>SF</Initials><AffiliationInfo><Affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fang</LastName><ForeName>Vicky J</ForeName><Initials>VJ</Initials><AffiliationInfo><Affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Skakni</LastName><ForeName>Leila</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Joseph</LastName><ForeName>Mercy</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wani</LastName><ForeName>Tariq A</ForeName><Initials>TA</Initials><AffiliationInfo><Affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cowling</LastName><ForeName>Benjamin J</ForeName><Initials>BJ</Initials><AffiliationInfo><Affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peiris</LastName><ForeName>Malik</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>School of Public Health, The University of Hong Kong, Hong Kong SAR.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hakawi</LastName><ForeName>Ahmed</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>King Fahad Medical City, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>HHSN272201400006C</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>11</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>PLoS One</MedlineTA><NlmUniqueID>101285081</NlmUniqueID><ISSNLinking>1932-6203</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000208" MajorTopicYN="N">Acute Disease</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015897" MajorTopicYN="N">Comorbidity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="Y">Hospitalization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053208" MajorTopicYN="N">Kaplan-Meier Estimate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065207" MajorTopicYN="N">Middle East Respiratory Syndrome Coronavirus</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><CoiStatement>The authors have declared that no competing interests exist.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>08</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>10</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>11</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>6</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>11</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27812197</ArticleId><ArticleId IdType="doi">10.1371/journal.pone.0165978</ArticleId><ArticleId IdType="pii">PONE-D-16-32266</ArticleId><ArticleId IdType="pmc">PMC5094725</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Ann Thorac Med. 2016 Apr-Jun;11(2):128-31</Citation><ArticleIdList><ArticleId IdType="pubmed">27168861</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2016 May;22(5):794-801</Citation><ArticleIdList><ArticleId IdType="pubmed">27089550</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2012 Nov 8;367 (19):1814-20</Citation><ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2015 Nov;21(11):1981-8</Citation><ArticleIdList><ArticleId IdType="pubmed">26484549</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2013 Jun 29;381(9885):2265-72</Citation><ArticleIdList><ArticleId IdType="pubmed">23727167</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2015 Feb 26;372(9):846-54</Citation><ArticleIdList><ArticleId IdType="pubmed">25714162</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2014 Jun 26;370(26):2499-505</Citation><ArticleIdList><ArticleId IdType="pubmed">24896817</ArticleId></ArticleIdList></Reference><Reference><Citation>Osong Public Health Res Perspect. 2015 Aug;6(4):269-78</Citation><ArticleIdList><ArticleId IdType="pubmed">26473095</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2013 Aug 29;369(9):884-6</Citation><ArticleIdList><ArticleId IdType="pubmed">23923992</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Infect Dis. 2014 Jul 15;59(2):160-5</Citation><ArticleIdList><ArticleId IdType="pubmed">24723278</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2016 Jan;22(1):49-55</Citation><ArticleIdList><ArticleId IdType="pubmed">26692185</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Intern Med. 2014 Mar 18;160(6):389-97</Citation><ArticleIdList><ArticleId IdType="pubmed">24474051</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2013 Sep;13(9):752-61</Citation><ArticleIdList><ArticleId IdType="pubmed">23891402</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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