Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of corpus callosum in Chinese children.
Identifieur interne : 000F01 ( PubMed/Corpus ); précédent : 000F00; suivant : 000F02Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of corpus callosum in Chinese children.
Auteurs : Qiong Fang ; Lang Chen ; Qiaobin Chen ; Zhi Lin ; Fang YangSource :
- Brain & development [ 1872-7131 ] ; 2017.
English descriptors
- KwdEn :
- MESH :
- cerebrospinal fluid : Encephalitis.
- diagnostic imaging : Corpus Callosum, Encephalitis.
- drug therapy : Encephalitis.
- Child, Preschool, Female, Humans, Male, Prognosis, Treatment Outcome.
Abstract
To investigate the characteristics and etiology of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in Chinese children.
DOI: 10.1016/j.braindev.2016.10.009
PubMed: 27823946
Links to Exploration step
pubmed:27823946Le document en format XML
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<author><name sortKey="Fang, Qiong" sort="Fang, Qiong" uniqKey="Fang Q" first="Qiong" last="Fang">Qiong Fang</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: tiantian3618@163.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chen, Lang" sort="Chen, Lang" uniqKey="Chen L" first="Lang" last="Chen">Lang Chen</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: chenlang11@qq.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chen, Qiaobin" sort="Chen, Qiaobin" uniqKey="Chen Q" first="Qiaobin" last="Chen">Qiaobin Chen</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: chenqiaobin1973@sina.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lin, Zhi" sort="Lin, Zhi" uniqKey="Lin Z" first="Zhi" last="Lin">Zhi Lin</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: 874468512@qq.com.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Yang, Fang" sort="Yang, Fang" uniqKey="Yang F" first="Fang" last="Yang">Fang Yang</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: yangfang731023@sina.com.</nlm:affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of corpus callosum in Chinese children.</title>
<author><name sortKey="Fang, Qiong" sort="Fang, Qiong" uniqKey="Fang Q" first="Qiong" last="Fang">Qiong Fang</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: tiantian3618@163.com.</nlm:affiliation>
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<author><name sortKey="Chen, Lang" sort="Chen, Lang" uniqKey="Chen L" first="Lang" last="Chen">Lang Chen</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: chenlang11@qq.com.</nlm:affiliation>
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<author><name sortKey="Chen, Qiaobin" sort="Chen, Qiaobin" uniqKey="Chen Q" first="Qiaobin" last="Chen">Qiaobin Chen</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: chenqiaobin1973@sina.com.</nlm:affiliation>
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<author><name sortKey="Lin, Zhi" sort="Lin, Zhi" uniqKey="Lin Z" first="Zhi" last="Lin">Zhi Lin</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: 874468512@qq.com.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Yang, Fang" sort="Yang, Fang" uniqKey="Yang F" first="Fang" last="Yang">Fang Yang</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: yangfang731023@sina.com.</nlm:affiliation>
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<series><title level="j">Brain & development</title>
<idno type="eISSN">1872-7131</idno>
<imprint><date when="2017" type="published">2017</date>
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<term>Corpus Callosum (diagnostic imaging)</term>
<term>Encephalitis (cerebrospinal fluid)</term>
<term>Encephalitis (diagnostic imaging)</term>
<term>Encephalitis (drug therapy)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Prognosis</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" qualifier="cerebrospinal fluid" xml:lang="en"><term>Encephalitis</term>
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<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Corpus Callosum</term>
<term>Encephalitis</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Encephalitis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Prognosis</term>
<term>Treatment Outcome</term>
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<front><div type="abstract" xml:lang="en">To investigate the characteristics and etiology of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in Chinese children.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27823946</PMID>
<DateCompleted><Year>2017</Year>
<Month>03</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>03</Month>
<Day>30</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-7131</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>39</Volume>
<Issue>4</Issue>
<PubDate><Year>2017</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Brain & development</Title>
<ISOAbbreviation>Brain Dev.</ISOAbbreviation>
</Journal>
<ArticleTitle>Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of corpus callosum in Chinese children.</ArticleTitle>
<Pagination><MedlinePgn>321-326</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S0387-7604(16)30178-4</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.braindev.2016.10.009</ELocationID>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To investigate the characteristics and etiology of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in Chinese children.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We collected ten pediatric MERS patients from local hospital and enrolled another nineteen patients by reviewing the available literatures. The information of enrolled patients about clinical features, laboratory data, treatment strategies and prognoses were collected for further analysis.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 29 children, the median age of twenty-nine patients was (4.09±3.64) years old. The male-to-female ratio was 1.42:1.0. The major cause of MERS was viral infection. 18 patients had consciousness disturbance which was the most prominent syndrome. 18 patients had transient seizures and only one needed anticonvulsant treatment for long. 9 patients were observed serum sodium levels <135mEq/L. The cells and protein of cerebral spinal fluid (CSF) were increased in 3 patients. In all patients, brain MRI evaluation revealed typical lesion in splenium of the corpus callosum (SCC). 5 patients had additional lesions involving the periventricular white matter or bilateral centrum semiovale diagnosed. 3 patients were treated with antivirus treatment because of virus infection. 7 patients received corticosteroid. 2 patients received intravenous IVIG. As a result, all patients had fully recovered without neurological residual.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The result of present study suggests that Chinese children with MERS might have favorable prognosis, although there is still no guideline for treatment.</AbstractText>
<CopyrightInformation>Copyright © 2016 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Fang</LastName>
<ForeName>Qiong</ForeName>
<Initials>Q</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: tiantian3618@163.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Lang</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: chenlang11@qq.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Qiaobin</ForeName>
<Initials>Q</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: chenqiaobin1973@sina.com.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Lin</LastName>
<ForeName>Zhi</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: 874468512@qq.com.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Yang</LastName>
<ForeName>Fang</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Fujian Provincial Hospital, Provincial Clinical Medical College Affiliated to Fujian Medical University, 134 East Street, Fuzhou, Fujian 350001, PR China. Electronic address: yangfang731023@sina.com.</Affiliation>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
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<ArticleDate DateType="Electronic"><Year>2016</Year>
<Month>11</Month>
<Day>04</Day>
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<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>Brain Dev</MedlineTA>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName>
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<MeshHeading><DescriptorName UI="D003337" MajorTopicYN="N">Corpus Callosum</DescriptorName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
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<MeshHeading><DescriptorName UI="D004660" MajorTopicYN="N">Encephalitis</DescriptorName>
<QualifierName UI="Q000134" MajorTopicYN="N">cerebrospinal fluid</QualifierName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName>
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<MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Children</Keyword>
<Keyword MajorTopicYN="N">China</Keyword>
<Keyword MajorTopicYN="N">Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS)</Keyword>
<Keyword MajorTopicYN="N">Splenium of the corpus callosum (SCC)</Keyword>
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