Emerging Developments on Pathogenicity, Molecular Virulence, Epidemiology and Clinical Symptoms of Current Middle East Respiratory Syndrome Coronavirus (MERS-CoV).
Identifieur interne : 000D38 ( PubMed/Corpus ); précédent : 000D37; suivant : 000D39Emerging Developments on Pathogenicity, Molecular Virulence, Epidemiology and Clinical Symptoms of Current Middle East Respiratory Syndrome Coronavirus (MERS-CoV).
Auteurs : Kannan Subbaram ; Hemalatha Kannan ; Mansour Khalil GatashehSource :
- Hayati : journal of biosciences [ 1978-3019 ] ; 2017.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently reported virus that is associated with severe, life threatening and rapidly spreading primarily respiratory illness called the Middle East respiratory syndrome. MERS-CoV possesses a unique positive-sense single-stranded RNA and can undergo rapid mutation in the viral genome. This results in antigenic switching and genetic variation, finally leading to the emergence of novel and new MERS-CoV subtypes which are uncontrollable by vaccines. Researchers are also finding difficulties to sort out therapeutic intervention strategies for MERS-CoV. This virus can spread from human to human, but transmission from dromedary camels to humans plays a crucial epidemiological significance. Dromedary camel acts as "gene mixing vessels" for MERS-CoV and these virus particles undergo rapid change in them. Viral receptors called dipeptidyl peptidase-4 are important receptors for attachment and spread of MERS-CoV in humans. The current method of laboratory confirmation is through real-time polymerase chain reaction on bronchoalveolar lavage, sputum and tracheal aspirates. Unfortunately, till today there are no definite anti-viral drugs available for MERS-CoV.
DOI: 10.1016/j.hjb.2017.08.001
PubMed: 32288937
Links to Exploration step
pubmed:32288937Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Emerging Developments on Pathogenicity, Molecular Virulence, Epidemiology and Clinical Symptoms of Current Middle East Respiratory Syndrome Coronavirus (MERS-CoV).</title>
<author><name sortKey="Subbaram, Kannan" sort="Subbaram, Kannan" uniqKey="Subbaram K" first="Kannan" last="Subbaram">Kannan Subbaram</name>
<affiliation><nlm:affiliation>Department of Preparatory (Biology), Al-Ghad International Colleges for Applied Medical Sciences, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kannan, Hemalatha" sort="Kannan, Hemalatha" uniqKey="Kannan H" first="Hemalatha" last="Kannan">Hemalatha Kannan</name>
<affiliation><nlm:affiliation>Department of Laboratory Sciences & Pathology, Jimma University, Ethiopia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Khalil Gatasheh, Mansour" sort="Khalil Gatasheh, Mansour" uniqKey="Khalil Gatasheh M" first="Mansour" last="Khalil Gatasheh">Mansour Khalil Gatasheh</name>
<affiliation><nlm:affiliation>Department of Clinical Laboratory Sciences, Al-Ghad International Colleges for Applied Medical Sciences, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:32288937</idno>
<idno type="pmid">32288937</idno>
<idno type="doi">10.1016/j.hjb.2017.08.001</idno>
<idno type="wicri:Area/PubMed/Corpus">000D38</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D38</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Emerging Developments on Pathogenicity, Molecular Virulence, Epidemiology and Clinical Symptoms of Current Middle East Respiratory Syndrome Coronavirus (MERS-CoV).</title>
<author><name sortKey="Subbaram, Kannan" sort="Subbaram, Kannan" uniqKey="Subbaram K" first="Kannan" last="Subbaram">Kannan Subbaram</name>
<affiliation><nlm:affiliation>Department of Preparatory (Biology), Al-Ghad International Colleges for Applied Medical Sciences, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kannan, Hemalatha" sort="Kannan, Hemalatha" uniqKey="Kannan H" first="Hemalatha" last="Kannan">Hemalatha Kannan</name>
<affiliation><nlm:affiliation>Department of Laboratory Sciences & Pathology, Jimma University, Ethiopia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Khalil Gatasheh, Mansour" sort="Khalil Gatasheh, Mansour" uniqKey="Khalil Gatasheh M" first="Mansour" last="Khalil Gatasheh">Mansour Khalil Gatasheh</name>
<affiliation><nlm:affiliation>Department of Clinical Laboratory Sciences, Al-Ghad International Colleges for Applied Medical Sciences, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">Hayati : journal of biosciences</title>
<idno type="ISSN">1978-3019</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently reported virus that is associated with severe, life threatening and rapidly spreading primarily respiratory illness called the Middle East respiratory syndrome. MERS-CoV possesses a unique positive-sense single-stranded RNA and can undergo rapid mutation in the viral genome. This results in antigenic switching and genetic variation, finally leading to the emergence of novel and new MERS-CoV subtypes which are uncontrollable by vaccines. Researchers are also finding difficulties to sort out therapeutic intervention strategies for MERS-CoV. This virus can spread from human to human, but transmission from dromedary camels to humans plays a crucial epidemiological significance. Dromedary camel acts as "gene mixing vessels" for MERS-CoV and these virus particles undergo rapid change in them. Viral receptors called dipeptidyl peptidase-4 are important receptors for attachment and spread of MERS-CoV in humans. The current method of laboratory confirmation is through real-time polymerase chain reaction on bronchoalveolar lavage, sputum and tracheal aspirates. Unfortunately, till today there are no definite anti-viral drugs available for MERS-CoV.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32288937</PMID>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>18</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">1978-3019</ISSN>
<JournalIssue CitedMedium="Print"><Volume>24</Volume>
<Issue>2</Issue>
<PubDate><Year>2017</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Hayati : journal of biosciences</Title>
<ISOAbbreviation>Hayati</ISOAbbreviation>
</Journal>
<ArticleTitle>Emerging Developments on Pathogenicity, Molecular Virulence, Epidemiology and Clinical Symptoms of Current Middle East Respiratory Syndrome Coronavirus (MERS-CoV).</ArticleTitle>
<Pagination><MedlinePgn>53-56</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.hjb.2017.08.001</ELocationID>
<Abstract><AbstractText>Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently reported virus that is associated with severe, life threatening and rapidly spreading primarily respiratory illness called the Middle East respiratory syndrome. MERS-CoV possesses a unique positive-sense single-stranded RNA and can undergo rapid mutation in the viral genome. This results in antigenic switching and genetic variation, finally leading to the emergence of novel and new MERS-CoV subtypes which are uncontrollable by vaccines. Researchers are also finding difficulties to sort out therapeutic intervention strategies for MERS-CoV. This virus can spread from human to human, but transmission from dromedary camels to humans plays a crucial epidemiological significance. Dromedary camel acts as "gene mixing vessels" for MERS-CoV and these virus particles undergo rapid change in them. Viral receptors called dipeptidyl peptidase-4 are important receptors for attachment and spread of MERS-CoV in humans. The current method of laboratory confirmation is through real-time polymerase chain reaction on bronchoalveolar lavage, sputum and tracheal aspirates. Unfortunately, till today there are no definite anti-viral drugs available for MERS-CoV.</AbstractText>
<CopyrightInformation>© 2017 Institut Pertanian Bogor. Production and hosting by Elsevier B.V.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Subbaram</LastName>
<ForeName>Kannan</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Preparatory (Biology), Al-Ghad International Colleges for Applied Medical Sciences, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kannan</LastName>
<ForeName>Hemalatha</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Laboratory Sciences & Pathology, Jimma University, Ethiopia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Khalil Gatasheh</LastName>
<ForeName>Mansour</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Laboratory Sciences, Al-Ghad International Colleges for Applied Medical Sciences, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>09</Month>
<Day>14</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Indonesia</Country>
<MedlineTA>Hayati</MedlineTA>
<NlmUniqueID>101514774</NlmUniqueID>
<ISSNLinking>1978-3019</ISSNLinking>
</MedlineJournalInfo>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">+ssRNA</Keyword>
<Keyword MajorTopicYN="N">MERS-CoV</Keyword>
<Keyword MajorTopicYN="N">RT-PCR</Keyword>
<Keyword MajorTopicYN="N">genetic rearrangement</Keyword>
<Keyword MajorTopicYN="N">virulence</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year>
<Month>03</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2017</Year>
<Month>07</Month>
<Day>28</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>08</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>4</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>4</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>4</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>1</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32288937</ArticleId>
<ArticleId IdType="doi">10.1016/j.hjb.2017.08.001</ArticleId>
<ArticleId IdType="pii">S1978-3019(17)30115-8</ArticleId>
<ArticleId IdType="pmc">PMC7104923</ArticleId>
</ArticleIdList>
<pmc-dir>pmcsd</pmc-dir>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16598-603</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24062443</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Euro Surveill. 2014 Jun 12;19(23):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24957745</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 2012 Jul;93(Pt 7):1385-1409</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22535777</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lancet Infect Dis. 2014 Feb;14(2):140-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24355866</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 2014 Feb;95(Pt 2):408-412</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24197535</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2014 Nov;88(21):12511-27</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25142582</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2014 Jan;88(1):717-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24131722</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>mBio. 2012 Nov 20;3(6):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23170002</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Antiviral Res. 2014 Sep;109:72-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24992731</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 2013 Dec;94(Pt 12):2679-2690</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24077366</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2013 Nov;87(21):11950-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23986586</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Biomed Sci. 2014 Jun 04;21:54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24898546</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Open Forum Infect Dis. 2016 Aug 03;3(3):ofw165</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27704019</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2012 Nov 8;367(19):1814-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2014 Feb;450-451:64-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24503068</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2013 Nov;87(21):11955-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23986593</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2014 Apr;454-455:197-205</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24725946</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>PLoS One. 2013 Jul 02;8(7):e69127</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23844250</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2014 Jun 26;370(26):2499-505</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24896817</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D38 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000D38 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:32288937 |texte= Emerging Developments on Pathogenicity, Molecular Virulence, Epidemiology and Clinical Symptoms of Current Middle East Respiratory Syndrome Coronavirus (MERS-CoV). }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:32288937" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |