Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents.
Identifieur interne : 000D20 ( PubMed/Corpus ); précédent : 000D19; suivant : 000D21Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents.
Auteurs : Ryan Ritterson ; Rocco CasagrandeSource :
- mSphere [ 2379-5042 ]
Abstract
Our firm conducted a risk/benefit assessment of "gain-of-function" research, as part of the deliberative process following a U.S. moratorium on the research (U.S. Department of Health and Human Services, U.S. Government Gain-of-Function Deliberative Process and Research Funding Pause on Selected Gain-of-Function Research Involving Influenza, MERS, and SARS Viruses, 2014). Due to significant missing but theoretically acquirable data, our biosafety assessment faced limitations, and we were forced to provide a relative, instead of absolute, measure of risk (Gryphon Scientific, LLC, Risk and Benefit Analysis of Gain of Function Research, 2016). Here, we argue that many of these types of missing data represent large and stunning gaps in our knowledge of biosafety and argue that these missing data, once acquired via primary research efforts, would improve biosafety risk assessments and could be incorporated into biosafety practices to reduce risk of accidents. Governments invest billions in biological research; at least a small fraction of this support is warranted to prevent biological accidents.
DOI: 10.1128/mSphere.00010-17
PubMed: 28405626
Links to Exploration step
pubmed:28405626Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents.</title><author><name sortKey="Ritterson, Ryan" sort="Ritterson, Ryan" uniqKey="Ritterson R" first="Ryan" last="Ritterson">Ryan Ritterson</name><affiliation><nlm:affiliation>Gryphon Scientific, LLC, Takoma Park, Maryland, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Casagrande, Rocco" sort="Casagrande, Rocco" uniqKey="Casagrande R" first="Rocco" last="Casagrande">Rocco Casagrande</name><affiliation><nlm:affiliation>Gryphon Scientific, LLC, Takoma Park, Maryland, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2017 Mar-Apr</MedlineDate></PubDate></date><idno type="RBID">pubmed:28405626</idno><idno type="pmid">28405626</idno><idno type="doi">10.1128/mSphere.00010-17</idno><idno type="wicri:Area/PubMed/Corpus">000D20</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D20</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents.</title><author><name sortKey="Ritterson, Ryan" sort="Ritterson, Ryan" uniqKey="Ritterson R" first="Ryan" last="Ritterson">Ryan Ritterson</name><affiliation><nlm:affiliation>Gryphon Scientific, LLC, Takoma Park, Maryland, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Casagrande, Rocco" sort="Casagrande, Rocco" uniqKey="Casagrande R" first="Rocco" last="Casagrande">Rocco Casagrande</name><affiliation><nlm:affiliation>Gryphon Scientific, LLC, Takoma Park, Maryland, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">mSphere</title><idno type="ISSN">2379-5042</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Our firm conducted a risk/benefit assessment of "gain-of-function" research, as part of the deliberative process following a U.S. moratorium on the research (U.S. Department of Health and Human Services, <i>U.S. Government Gain-of-Function Deliberative Process and Research Funding Pause on Selected Gain-of-Function Research Involving Influenza</i>, <i>MERS</i>, <i>and SARS Viruses</i>, 2014). Due to significant missing but theoretically acquirable data, our biosafety assessment faced limitations, and we were forced to provide a relative, instead of absolute, measure of risk (Gryphon Scientific, LLC, <i>Risk and Benefit Analysis of Gain of Function Research</i>, 2016). Here, we argue that many of these types of missing data represent large and stunning gaps in our knowledge of biosafety and argue that these missing data, once acquired via primary research efforts, would improve biosafety risk assessments and could be incorporated into biosafety practices to reduce risk of accidents. Governments invest billions in biological research; at least a small fraction of this support is warranted to prevent biological accidents.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">28405626</PMID><DateRevised><Year>2019</Year><Month>11</Month><Day>20</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Print">2379-5042</ISSN><JournalIssue CitedMedium="Print"><Volume>2</Volume><Issue>2</Issue><PubDate><MedlineDate>2017 Mar-Apr</MedlineDate></PubDate></JournalIssue><Title>mSphere</Title><ISOAbbreviation>mSphere</ISOAbbreviation></Journal><ArticleTitle>Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">e00010-17</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1128/mSphere.00010-17</ELocationID><Abstract><AbstractText>Our firm conducted a risk/benefit assessment of "gain-of-function" research, as part of the deliberative process following a U.S. moratorium on the research (U.S. Department of Health and Human Services, <i>U.S. Government Gain-of-Function Deliberative Process and Research Funding Pause on Selected Gain-of-Function Research Involving Influenza</i>, <i>MERS</i>, <i>and SARS Viruses</i>, 2014). Due to significant missing but theoretically acquirable data, our biosafety assessment faced limitations, and we were forced to provide a relative, instead of absolute, measure of risk (Gryphon Scientific, LLC, <i>Risk and Benefit Analysis of Gain of Function Research</i>, 2016). Here, we argue that many of these types of missing data represent large and stunning gaps in our knowledge of biosafety and argue that these missing data, once acquired via primary research efforts, would improve biosafety risk assessments and could be incorporated into biosafety practices to reduce risk of accidents. Governments invest billions in biological research; at least a small fraction of this support is warranted to prevent biological accidents.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ritterson</LastName><ForeName>Ryan</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Gryphon Scientific, LLC, Takoma Park, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Casagrande</LastName><ForeName>Rocco</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Gryphon Scientific, LLC, Takoma Park, Maryland, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>03</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>mSphere</MedlineTA><NlmUniqueID>101674533</NlmUniqueID><ISSNLinking>2379-5042</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">biosafety</Keyword><Keyword MajorTopicYN="N">conduct of research</Keyword><Keyword MajorTopicYN="N">gain of function</Keyword><Keyword MajorTopicYN="N">science policy</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>4</Month><Day>14</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28405626</ArticleId><ArticleId IdType="doi">10.1128/mSphere.00010-17</ArticleId><ArticleId IdType="pii">mSphere00010-17</ArticleId><ArticleId IdType="pmc">PMC5371692</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1975 Jun;72(6):1981-4</Citation><ArticleIdList><ArticleId IdType="pubmed">806076</ArticleId></ArticleIdList></Reference><Reference><Citation>J Am Vet Med Assoc. 2014 Aug 15;245(4):434-40</Citation><ArticleIdList><ArticleId IdType="pubmed">25075828</ArticleId></ArticleIdList></Reference><Reference><Citation>BMJ. 2000 Mar 18;320(7237):759-63</Citation><ArticleIdList><ArticleId IdType="pubmed">10720361</ArticleId></ArticleIdList></Reference><Reference><Citation>Risk Anal. 2003 Jun;23(3):445-59</Citation><ArticleIdList><ArticleId IdType="pubmed">12836838</ArticleId></ArticleIdList></Reference><Reference><Citation>BMJ. 2014 Jul 14;349:g4615</Citation><ArticleIdList><ArticleId IdType="pubmed">25022658</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D20 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000D20 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:28405626
|texte= Basic Scholarship in Biosafety Is Critically Needed To Reduce Risk of Laboratory Accidents.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:28405626" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |