MersV1, PubMed, Corpus, bibRecord, 000943

Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: A Saudi Arabian multicenter retrospective study.

Identifieur interne : 000943 ( PubMed/Corpus ); précédent : 000942; suivant : 000944

Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: A Saudi Arabian multicenter retrospective study.

Auteurs : Anwar E. Ahmed ; Hamdan Al-Jahdali ; Mody Alaqeel ; Salma S. Siddiq ; Hanan A. Alsaab ; Ezzeldin A. Sakr ; Hamed A. Alyahya ; Munzir M. Alandonisi ; Alaa T. Subedar ; Yosra Z. Ali ; Hazza Al Otaibi ; Nouf M. Aloudah ; Salim Baharoon ; Sameera Al Johani ; Mohammed G. Alghamdi

Source :

Influenza and other respiratory viruses [ 1750-2659 ] ; 2018.

RBID : pubmed:29624866

English descriptors

KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Child, Child, Preschool, Coronavirus Infections (epidemiology), Coronavirus Infections (pathology), Female, Humans, Infant, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (isolation & purification), Real-Time Polymerase Chain Reaction, Remission, Spontaneous, Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction, Saudi Arabia (epidemiology), Time Factors, Young Adult.
MESH :
- geographic , epidemiology : Saudi Arabia.
- epidemiology : Coronavirus Infections.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- pathology : Coronavirus Infections.
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Child, Child, Preschool, Female, Humans, Infant, Male, Middle Aged, Real-Time Polymerase Chain Reaction, Remission, Spontaneous, Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, Young Adult.

Abstract

Research evidence exists that poor prognosis is common in Middle East respiratory syndrome coronavirus (MERS-CoV) patients.

DOI: 10.1111/irv.12560
PubMed: 29624866

Links to Exploration step

pubmed:29624866

Le document en format XML

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<author><name sortKey="Aloudah, Nouf M" sort="Aloudah, Nouf M" uniqKey="Aloudah N" first="Nouf M" last="Aloudah">Nouf M. Aloudah</name>
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</affiliation>
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<author><name sortKey="Al Johani, Sameera" sort="Al Johani, Sameera" uniqKey="Al Johani S" first="Sameera" last="Al Johani">Sameera Al Johani</name>
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<author><name sortKey="Alghamdi, Mohammed G" sort="Alghamdi, Mohammed G" uniqKey="Alghamdi M" first="Mohammed G" last="Alghamdi">Mohammed G. Alghamdi</name>
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</affiliation>
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<author><name sortKey="Alaqeel, Mody" sort="Alaqeel, Mody" uniqKey="Alaqeel M" first="Mody" last="Alaqeel">Mody Alaqeel</name>
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<author><name sortKey="Alyahya, Hamed A" sort="Alyahya, Hamed A" uniqKey="Alyahya H" first="Hamed A" last="Alyahya">Hamed A. Alyahya</name>
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<author><name sortKey="Alandonisi, Munzir M" sort="Alandonisi, Munzir M" uniqKey="Alandonisi M" first="Munzir M" last="Alandonisi">Munzir M. Alandonisi</name>
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<author><name sortKey="Subedar, Alaa T" sort="Subedar, Alaa T" uniqKey="Subedar A" first="Alaa T" last="Subedar">Alaa T. Subedar</name>
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<author><name sortKey="Ali, Yosra Z" sort="Ali, Yosra Z" uniqKey="Ali Y" first="Yosra Z" last="Ali">Yosra Z. Ali</name>
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</affiliation>
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<author><name sortKey="Al Otaibi, Hazza" sort="Al Otaibi, Hazza" uniqKey="Al Otaibi H" first="Hazza" last="Al Otaibi">Hazza Al Otaibi</name>
<affiliation><nlm:affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Aloudah, Nouf M" sort="Aloudah, Nouf M" uniqKey="Aloudah N" first="Nouf M" last="Aloudah">Nouf M. Aloudah</name>
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</affiliation>
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<author><name sortKey="Baharoon, Salim" sort="Baharoon, Salim" uniqKey="Baharoon S" first="Salim" last="Baharoon">Salim Baharoon</name>
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</affiliation>
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<author><name sortKey="Al Johani, Sameera" sort="Al Johani, Sameera" uniqKey="Al Johani S" first="Sameera" last="Al Johani">Sameera Al Johani</name>
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</affiliation>
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<author><name sortKey="Alghamdi, Mohammed G" sort="Alghamdi, Mohammed G" uniqKey="Alghamdi M" first="Mohammed G" last="Alghamdi">Mohammed G. Alghamdi</name>
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</affiliation>
</author>
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<series><title level="j">Influenza and other respiratory viruses</title>
<idno type="eISSN">1750-2659</idno>
<imprint><date when="2018" type="published">2018</date>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Animals</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (pathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Middle East Respiratory Syndrome Coronavirus (genetics)</term>
<term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term>
<term>Real-Time Polymerase Chain Reaction</term>
<term>Remission, Spontaneous</term>
<term>Retrospective Studies</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>Saudi Arabia (epidemiology)</term>
<term>Time Factors</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Saudi Arabia</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Animals</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Real-Time Polymerase Chain Reaction</term>
<term>Remission, Spontaneous</term>
<term>Retrospective Studies</term>
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<front><div type="abstract" xml:lang="en">Research evidence exists that poor prognosis is common in Middle East respiratory syndrome coronavirus (MERS-CoV) patients.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29624866</PMID>
<DateCompleted><Year>2019</Year>
<Month>11</Month>
<Day>07</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1750-2659</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>12</Volume>
<Issue>5</Issue>
<PubDate><Year>2018</Year>
<Month>09</Month>
</PubDate>
</JournalIssue>
<Title>Influenza and other respiratory viruses</Title>
<ISOAbbreviation>Influenza Other Respir Viruses</ISOAbbreviation>
</Journal>
<ArticleTitle>Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: A Saudi Arabian multicenter retrospective study.</ArticleTitle>
<Pagination><MedlinePgn>656-661</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/irv.12560</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Research evidence exists that poor prognosis is common in Middle East respiratory syndrome coronavirus (MERS-CoV) patients.</AbstractText>
<AbstractText Label="OBJECTIVES">This study estimates recovery delay intervals and identifies associated factors in a sample of Saudi Arabian patients admitted for suspected MERS-CoV and diagnosed by rRT-PCR assay.</AbstractText>
<AbstractText Label="METHODS">A multicenter retrospective study was conducted on 829 patients admitted between September 2012 and June 2016 and diagnosed by rRT-PCR procedures to have MERS-CoV and non-MERS-CoV infection in which 396 achieved recovery. Detailed medical charts were reviewed for each patient who achieved recovery. Time intervals in days were calculated from presentation to the initial rRT-PCR diagnosis (diagnosis delay) and from the initial rRT-PCR diagnosis to recovery (recovery delay).</AbstractText>
<AbstractText Label="RESULTS">The median recovery delay in our sample was 5 days. According to the multivariate negative binomial model, elderly (age ≥ 65), MERS-CoV infection, ICU admission, and abnormal radiology findings were associated with longer recovery delay (adjusted relative risk (aRR): 1.741, 2.138, 2.048, and 1.473, respectively). Camel contact and the presence of respiratory symptoms at presentation were associated with a shorter recovery delay (expedited recovery) (aRR: 0.267 and 0.537, respectively). Diagnosis delay is a positive predictor for recovery delay (r = .421; P = .001).</AbstractText>
<AbstractText Label="CONCLUSIONS">The study evidence supports that longer recovery delay was seen in patients of older age, MERS-CoV infection, ICU admission, and abnormal radiology findings. Shorter recovery delay was found in patients who had camel contact and respiratory symptoms at presentation. These findings may help us understand clinical decision making on directing hospital resources toward prompt screening, monitoring, and implementing clinical recovery and treatment strategies.</AbstractText>
<CopyrightInformation>© 2018 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ahmed</LastName>
<ForeName>Anwar E</ForeName>
<Initials>AE</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0001-8743-6007</Identifier>
<AffiliationInfo><Affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al-Jahdali</LastName>
<ForeName>Hamdan</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alaqeel</LastName>
<ForeName>Mody</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Siddiq</LastName>
<ForeName>Salma S</ForeName>
<Initials>SS</Initials>
<AffiliationInfo><Affiliation>King Fahad General Hospital - Jeddah, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alsaab</LastName>
<ForeName>Hanan A</ForeName>
<Initials>HA</Initials>
<AffiliationInfo><Affiliation>Medical Records Department, Ministry of Health, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sakr</LastName>
<ForeName>Ezzeldin A</ForeName>
<Initials>EA</Initials>
<AffiliationInfo><Affiliation>King Fahad General Hospital - Jeddah, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alyahya</LastName>
<ForeName>Hamed A</ForeName>
<Initials>HA</Initials>
<AffiliationInfo><Affiliation>King Fahad General Hospital - Jeddah, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alandonisi</LastName>
<ForeName>Munzir M</ForeName>
<Initials>MM</Initials>
<AffiliationInfo><Affiliation>King Fahad General Hospital - Jeddah, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Subedar</LastName>
<ForeName>Alaa T</ForeName>
<Initials>AT</Initials>
<AffiliationInfo><Affiliation>King Fahad General Hospital - Jeddah, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ali</LastName>
<ForeName>Yosra Z</ForeName>
<Initials>YZ</Initials>
<AffiliationInfo><Affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al Otaibi</LastName>
<ForeName>Hazza</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Aloudah</LastName>
<ForeName>Nouf M</ForeName>
<Initials>NM</Initials>
<AffiliationInfo><Affiliation>King Saud University, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baharoon</LastName>
<ForeName>Salim</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al Johani</LastName>
<ForeName>Sameera</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>King Abdullah International Medical Research Center (KAIMRC)/King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)/King Abdulaziz Medical City (KAMC), Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alghamdi</LastName>
<ForeName>Mohammed G</ForeName>
<Initials>MG</Initials>
<AffiliationInfo><Affiliation>King Fahad General Hospital - Jeddah, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>08-1</GrantID>
<Agency>King Abdulaziz City for Science and Technology</Agency>
<Country>International</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016448">Multicenter Study</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>04</Month>
<Day>25</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Influenza Other Respir Viruses</MedlineTA>
<NlmUniqueID>101304007</NlmUniqueID>
<ISSNLinking>1750-2640</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
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</MeshHeading>
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Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: A Saudi Arabian multicenter retrospective study.

Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: A Saudi Arabian multicenter retrospective study.

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