MersV1, PubMed, Corpus, bibRecord, 000730

Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.

Identifieur interne : 000730 ( PubMed/Corpus ); précédent : 000729; suivant : 000731

Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.

Auteurs : Sarah Shalhoub ; Fahad Al-Hameed ; Yasser Mandourah ; Hanan H. Balkhy ; Awad Al-Omari ; Ghaleb A. Al Mekhlafi ; Ayman Kharaba ; Basem Alraddadi ; Abdullah Almotairi ; Kasim Al Khatib ; Ahmed Abdulmomen ; Ismael Qushmaq ; Ahmed Mady ; Othman Solaiman ; Abdulsalam M. Al-Aithan ; Rajaa Al-Raddadi ; Ahmed Ragab ; Abdulrahman Al Harthy ; Eman Al Qasim ; Jesna Jose ; Ghassan Al-Ghamdi ; Laura Merson ; Robert Fowler ; Frederick G. Hayden ; Yaseen M. Arabi

Source :

PloS one [ 1932-6203 ] ; 2018.

RBID : pubmed:30439974

English descriptors

KwdEn :
- Adult, Comorbidity, Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (therapy), Coronavirus Infections (virology), Critical Illness (epidemiology), Critical Illness (therapy), Cross Infection (diagnosis), Cross Infection (epidemiology), Cross Infection (therapy), Cross Infection (virology), Disease Outbreaks, Extracorporeal Membrane Oxygenation (statistics & numerical data), Female, Health Personnel (statistics & numerical data), Hospital Mortality, Humans, Karnofsky Performance Status, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (isolation & purification), Occupational Diseases (diagnosis), Occupational Diseases (epidemiology), Occupational Diseases (therapy), Occupational Diseases (virology), Retrospective Studies, Saudi Arabia (epidemiology), Survival Rate.
MESH :
- geographic , epidemiology : Saudi Arabia.
- diagnosis : Coronavirus Infections, Cross Infection, Occupational Diseases.
- epidemiology : Coronavirus Infections, Critical Illness, Cross Infection, Occupational Diseases.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- statistics & numerical data : Extracorporeal Membrane Oxygenation, Health Personnel.
- therapy : Coronavirus Infections, Critical Illness, Cross Infection, Occupational Diseases.
- virology : Coronavirus Infections, Cross Infection, Occupational Diseases.
- Adult, Comorbidity, Disease Outbreaks, Female, Hospital Mortality, Humans, Karnofsky Performance Status, Male, Middle Aged, Retrospective Studies, Survival Rate.

Abstract

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) leads to healthcare-associated transmission to patients and healthcare workers with potentially fatal outcomes.

DOI: 10.1371/journal.pone.0206831
PubMed: 30439974

Links to Exploration step

pubmed:30439974

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.</title>
<author><name sortKey="Shalhoub, Sarah" sort="Shalhoub, Sarah" uniqKey="Shalhoub S" first="Sarah" last="Shalhoub">Sarah Shalhoub</name>
<affiliation><nlm:affiliation>Department of Medicine, Division of Infectious Diseases, University of Western Ontario, London, Canada, Department of Medicine, Division of Infectious Diseases, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Hameed, Fahad" sort="Al Hameed, Fahad" uniqKey="Al Hameed F" first="Fahad" last="Al-Hameed">Fahad Al-Hameed</name>
<affiliation><nlm:affiliation>Department of Intensive Care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mandourah, Yasser" sort="Mandourah, Yasser" uniqKey="Mandourah Y" first="Yasser" last="Mandourah">Yasser Mandourah</name>
<affiliation><nlm:affiliation>Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Balkhy, Hanan H" sort="Balkhy, Hanan H" uniqKey="Balkhy H" first="Hanan H" last="Balkhy">Hanan H. Balkhy</name>
<affiliation><nlm:affiliation>Department of Infection Prevention and Control, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Omari, Awad" sort="Al Omari, Awad" uniqKey="Al Omari A" first="Awad" last="Al-Omari">Awad Al-Omari</name>
<affiliation><nlm:affiliation>Department of Intensive Care, Alfaisal University, Dr Sulaiman Al-Habib Group Hospitals, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Mekhlafi, Ghaleb A" sort="Al Mekhlafi, Ghaleb A" uniqKey="Al Mekhlafi G" first="Ghaleb A" last="Al Mekhlafi">Ghaleb A. Al Mekhlafi</name>
<affiliation><nlm:affiliation>Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kharaba, Ayman" sort="Kharaba, Ayman" uniqKey="Kharaba A" first="Ayman" last="Kharaba">Ayman Kharaba</name>
<affiliation><nlm:affiliation>Department of Critical Care, King Fahad Hospital, Ohoud Hospital, Al-Madinah Al-Monawarah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Alraddadi, Basem" sort="Alraddadi, Basem" uniqKey="Alraddadi B" first="Basem" last="Alraddadi">Basem Alraddadi</name>
<affiliation><nlm:affiliation>Department of Medicine, Alfaisal University, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Almotairi, Abdullah" sort="Almotairi, Abdullah" uniqKey="Almotairi A" first="Abdullah" last="Almotairi">Abdullah Almotairi</name>
<affiliation><nlm:affiliation>Department of Critical Care Medicine, King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Khatib, Kasim" sort="Al Khatib, Kasim" uniqKey="Al Khatib K" first="Kasim" last="Al Khatib">Kasim Al Khatib</name>
<affiliation><nlm:affiliation>Intensive Care Department, Al-Noor Specialist Hospital, Makkah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Abdulmomen, Ahmed" sort="Abdulmomen, Ahmed" uniqKey="Abdulmomen A" first="Ahmed" last="Abdulmomen">Ahmed Abdulmomen</name>
<affiliation><nlm:affiliation>Department of Critical Care Medicine, King Saud University, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Qushmaq, Ismael" sort="Qushmaq, Ismael" uniqKey="Qushmaq I" first="Ismael" last="Qushmaq">Ismael Qushmaq</name>
<affiliation><nlm:affiliation>Department of Medicine, Alfaisal University, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mady, Ahmed" sort="Mady, Ahmed" uniqKey="Mady A" first="Ahmed" last="Mady">Ahmed Mady</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Solaiman, Othman" sort="Solaiman, Othman" uniqKey="Solaiman O" first="Othman" last="Solaiman">Othman Solaiman</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Aithan, Abdulsalam M" sort="Al Aithan, Abdulsalam M" uniqKey="Al Aithan A" first="Abdulsalam M" last="Al-Aithan">Abdulsalam M. Al-Aithan</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Abdulaziz Hospital, Al Ahsa, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Raddadi, Rajaa" sort="Al Raddadi, Rajaa" uniqKey="Al Raddadi R" first="Rajaa" last="Al-Raddadi">Rajaa Al-Raddadi</name>
<affiliation><nlm:affiliation>Department of Family and Community Medicine, King Abdulaziz University Hospital, Ministry of Health, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ragab, Ahmed" sort="Ragab, Ahmed" uniqKey="Ragab A" first="Ahmed" last="Ragab">Ahmed Ragab</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Fahd Hospital, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Harthy, Abdulrahman" sort="Al Harthy, Abdulrahman" uniqKey="Al Harthy A" first="Abdulrahman" last="Al Harthy">Abdulrahman Al Harthy</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Qasim, Eman" sort="Al Qasim, Eman" uniqKey="Al Qasim E" first="Eman" last="Al Qasim">Eman Al Qasim</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jose, Jesna" sort="Jose, Jesna" uniqKey="Jose J" first="Jesna" last="Jose">Jesna Jose</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Ghamdi, Ghassan" sort="Al Ghamdi, Ghassan" uniqKey="Al Ghamdi G" first="Ghassan" last="Al-Ghamdi">Ghassan Al-Ghamdi</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Merson, Laura" sort="Merson, Laura" uniqKey="Merson L" first="Laura" last="Merson">Laura Merson</name>
<affiliation><nlm:affiliation>Infectious Diseases Data Observatory, Oxford University, Headiington, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fowler, Robert" sort="Fowler, Robert" uniqKey="Fowler R" first="Robert" last="Fowler">Robert Fowler</name>
<affiliation><nlm:affiliation>Department of Critical Care Medicine and Department of Medicine, Sunnybrook Hospital, Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hayden, Frederick G" sort="Hayden, Frederick G" uniqKey="Hayden F" first="Frederick G" last="Hayden">Frederick G. Hayden</name>
<affiliation><nlm:affiliation>Department of Medicine, Division of Infectious Diseases and International Health University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Arabi, Yaseen M" sort="Arabi, Yaseen M" uniqKey="Arabi Y" first="Yaseen M" last="Arabi">Yaseen M. Arabi</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
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<date when="2018">2018</date>
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<idno type="pmid">30439974</idno>
<idno type="doi">10.1371/journal.pone.0206831</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.</title>
<author><name sortKey="Shalhoub, Sarah" sort="Shalhoub, Sarah" uniqKey="Shalhoub S" first="Sarah" last="Shalhoub">Sarah Shalhoub</name>
<affiliation><nlm:affiliation>Department of Medicine, Division of Infectious Diseases, University of Western Ontario, London, Canada, Department of Medicine, Division of Infectious Diseases, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Hameed, Fahad" sort="Al Hameed, Fahad" uniqKey="Al Hameed F" first="Fahad" last="Al-Hameed">Fahad Al-Hameed</name>
<affiliation><nlm:affiliation>Department of Intensive Care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mandourah, Yasser" sort="Mandourah, Yasser" uniqKey="Mandourah Y" first="Yasser" last="Mandourah">Yasser Mandourah</name>
<affiliation><nlm:affiliation>Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Balkhy, Hanan H" sort="Balkhy, Hanan H" uniqKey="Balkhy H" first="Hanan H" last="Balkhy">Hanan H. Balkhy</name>
<affiliation><nlm:affiliation>Department of Infection Prevention and Control, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Omari, Awad" sort="Al Omari, Awad" uniqKey="Al Omari A" first="Awad" last="Al-Omari">Awad Al-Omari</name>
<affiliation><nlm:affiliation>Department of Intensive Care, Alfaisal University, Dr Sulaiman Al-Habib Group Hospitals, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Mekhlafi, Ghaleb A" sort="Al Mekhlafi, Ghaleb A" uniqKey="Al Mekhlafi G" first="Ghaleb A" last="Al Mekhlafi">Ghaleb A. Al Mekhlafi</name>
<affiliation><nlm:affiliation>Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kharaba, Ayman" sort="Kharaba, Ayman" uniqKey="Kharaba A" first="Ayman" last="Kharaba">Ayman Kharaba</name>
<affiliation><nlm:affiliation>Department of Critical Care, King Fahad Hospital, Ohoud Hospital, Al-Madinah Al-Monawarah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Alraddadi, Basem" sort="Alraddadi, Basem" uniqKey="Alraddadi B" first="Basem" last="Alraddadi">Basem Alraddadi</name>
<affiliation><nlm:affiliation>Department of Medicine, Alfaisal University, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Almotairi, Abdullah" sort="Almotairi, Abdullah" uniqKey="Almotairi A" first="Abdullah" last="Almotairi">Abdullah Almotairi</name>
<affiliation><nlm:affiliation>Department of Critical Care Medicine, King Fahad Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Khatib, Kasim" sort="Al Khatib, Kasim" uniqKey="Al Khatib K" first="Kasim" last="Al Khatib">Kasim Al Khatib</name>
<affiliation><nlm:affiliation>Intensive Care Department, Al-Noor Specialist Hospital, Makkah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Abdulmomen, Ahmed" sort="Abdulmomen, Ahmed" uniqKey="Abdulmomen A" first="Ahmed" last="Abdulmomen">Ahmed Abdulmomen</name>
<affiliation><nlm:affiliation>Department of Critical Care Medicine, King Saud University, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Qushmaq, Ismael" sort="Qushmaq, Ismael" uniqKey="Qushmaq I" first="Ismael" last="Qushmaq">Ismael Qushmaq</name>
<affiliation><nlm:affiliation>Department of Medicine, Alfaisal University, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mady, Ahmed" sort="Mady, Ahmed" uniqKey="Mady A" first="Ahmed" last="Mady">Ahmed Mady</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Solaiman, Othman" sort="Solaiman, Othman" uniqKey="Solaiman O" first="Othman" last="Solaiman">Othman Solaiman</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Aithan, Abdulsalam M" sort="Al Aithan, Abdulsalam M" uniqKey="Al Aithan A" first="Abdulsalam M" last="Al-Aithan">Abdulsalam M. Al-Aithan</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Abdulaziz Hospital, Al Ahsa, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Raddadi, Rajaa" sort="Al Raddadi, Rajaa" uniqKey="Al Raddadi R" first="Rajaa" last="Al-Raddadi">Rajaa Al-Raddadi</name>
<affiliation><nlm:affiliation>Department of Family and Community Medicine, King Abdulaziz University Hospital, Ministry of Health, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ragab, Ahmed" sort="Ragab, Ahmed" uniqKey="Ragab A" first="Ahmed" last="Ragab">Ahmed Ragab</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Fahd Hospital, Jeddah, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Harthy, Abdulrahman" sort="Al Harthy, Abdulrahman" uniqKey="Al Harthy A" first="Abdulrahman" last="Al Harthy">Abdulrahman Al Harthy</name>
<affiliation><nlm:affiliation>Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Qasim, Eman" sort="Al Qasim, Eman" uniqKey="Al Qasim E" first="Eman" last="Al Qasim">Eman Al Qasim</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jose, Jesna" sort="Jose, Jesna" uniqKey="Jose J" first="Jesna" last="Jose">Jesna Jose</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Ghamdi, Ghassan" sort="Al Ghamdi, Ghassan" uniqKey="Al Ghamdi G" first="Ghassan" last="Al-Ghamdi">Ghassan Al-Ghamdi</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Merson, Laura" sort="Merson, Laura" uniqKey="Merson L" first="Laura" last="Merson">Laura Merson</name>
<affiliation><nlm:affiliation>Infectious Diseases Data Observatory, Oxford University, Headiington, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fowler, Robert" sort="Fowler, Robert" uniqKey="Fowler R" first="Robert" last="Fowler">Robert Fowler</name>
<affiliation><nlm:affiliation>Department of Critical Care Medicine and Department of Medicine, Sunnybrook Hospital, Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hayden, Frederick G" sort="Hayden, Frederick G" uniqKey="Hayden F" first="Frederick G" last="Hayden">Frederick G. Hayden</name>
<affiliation><nlm:affiliation>Department of Medicine, Division of Infectious Diseases and International Health University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Arabi, Yaseen M" sort="Arabi, Yaseen M" uniqKey="Arabi Y" first="Yaseen M" last="Arabi">Yaseen M. Arabi</name>
<affiliation><nlm:affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
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<term>Comorbidity</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (therapy)</term>
<term>Coronavirus Infections (virology)</term>
<term>Critical Illness (epidemiology)</term>
<term>Critical Illness (therapy)</term>
<term>Cross Infection (diagnosis)</term>
<term>Cross Infection (epidemiology)</term>
<term>Cross Infection (therapy)</term>
<term>Cross Infection (virology)</term>
<term>Disease Outbreaks</term>
<term>Extracorporeal Membrane Oxygenation (statistics & numerical data)</term>
<term>Female</term>
<term>Health Personnel (statistics & numerical data)</term>
<term>Hospital Mortality</term>
<term>Humans</term>
<term>Karnofsky Performance Status</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term>
<term>Occupational Diseases (diagnosis)</term>
<term>Occupational Diseases (epidemiology)</term>
<term>Occupational Diseases (therapy)</term>
<term>Occupational Diseases (virology)</term>
<term>Retrospective Studies</term>
<term>Saudi Arabia (epidemiology)</term>
<term>Survival Rate</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Saudi Arabia</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term>
<term>Cross Infection</term>
<term>Occupational Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Critical Illness</term>
<term>Cross Infection</term>
<term>Occupational Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
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<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Extracorporeal Membrane Oxygenation</term>
<term>Health Personnel</term>
</keywords>
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<term>Critical Illness</term>
<term>Cross Infection</term>
<term>Occupational Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Cross Infection</term>
<term>Occupational Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Comorbidity</term>
<term>Disease Outbreaks</term>
<term>Female</term>
<term>Hospital Mortality</term>
<term>Humans</term>
<term>Karnofsky Performance Status</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
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<front><div type="abstract" xml:lang="en">Middle East Respiratory Syndrome Coronavirus (MERS-CoV) leads to healthcare-associated transmission to patients and healthcare workers with potentially fatal outcomes.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30439974</PMID>
<DateCompleted><Year>2019</Year>
<Month>04</Month>
<Day>15</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>04</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>13</Volume>
<Issue>11</Issue>
<PubDate><Year>2018</Year>
</PubDate>
</JournalIssue>
<Title>PloS one</Title>
<ISOAbbreviation>PLoS ONE</ISOAbbreviation>
</Journal>
<ArticleTitle>Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.</ArticleTitle>
<Pagination><MedlinePgn>e0206831</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0206831</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Middle East Respiratory Syndrome Coronavirus (MERS-CoV) leads to healthcare-associated transmission to patients and healthcare workers with potentially fatal outcomes.</AbstractText>
<AbstractText Label="AIM">We aimed to describe the clinical course and functional outcomes of critically ill healthcare workers (HCWs) with MERS.</AbstractText>
<AbstractText Label="METHODS">Data on HCWs was extracted from a multi-center retrospective cohort study on 330 critically ill patients with MERS admitted between (9/2012-9/2015). Baseline demographics, interventions and outcomes were recorded and compared between survivors and non-survivors. Survivors were approached with questionnaires to elucidate their functional outcomes using Karnofsky Performance Status Scale.</AbstractText>
<AbstractText Label="FINDINGS">Thirty-Two HCWs met the inclusion criteria. Comorbidities were recorded in 34% (11/32) HCW. Death resulted in 8/32 (25%) HCWs including all 5 HCWs with chronic renal impairment at baseline. Non-surviving HCW had lower PaO2/FiO2 ratios 63.5 (57, 116.2) vs 148 (84, 194.3), p = 0.043, and received more ECMO therapy compared to survivors, 9/32 (28%) vs 4/24 (16.7%) respectively (p = 0.02).Thirteen of the surviving (13/24) HCWs responded to the questionnaire. Two HCWs confirmed functional limitations. Median number of days from hospital discharge until the questionnaires were filled was 580 (95% CI 568, 723.5) days.</AbstractText>
<AbstractText Label="CONCLUSION">Approximately 10% of critically ill patients with MERS were HCWs. Hospital mortality rate was substantial (25%). Patients with chronic renal impairment represented a particularly high-risk group that should receive extra caution during suspected or confirmed MERS cases clinical care assignment and during outbreaks. Long-term repercussions of critical illness due to MERS on HCWs in particular, and patients in general, remain unknown and should be investigated in larger studies.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Shalhoub</LastName>
<ForeName>Sarah</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Division of Infectious Diseases, University of Western Ontario, London, Canada, Department of Medicine, Division of Infectious Diseases, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al-Hameed</LastName>
<ForeName>Fahad</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Intensive Care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mandourah</LastName>
<ForeName>Yasser</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Balkhy</LastName>
<ForeName>Hanan H</ForeName>
<Initials>HH</Initials>
<AffiliationInfo><Affiliation>Department of Infection Prevention and Control, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al-Omari</LastName>
<ForeName>Awad</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Intensive Care, Alfaisal University, Dr Sulaiman Al-Habib Group Hospitals, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al Mekhlafi</LastName>
<ForeName>Ghaleb A</ForeName>
<Initials>GA</Initials>
<AffiliationInfo><Affiliation>Department of Intensive Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kharaba</LastName>
<ForeName>Ayman</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Critical Care, King Fahad Hospital, Ohoud Hospital, Al-Madinah Al-Monawarah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alraddadi</LastName>
<ForeName>Basem</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Alfaisal University, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Almotairi</LastName>
<ForeName>Abdullah</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Critical Care Medicine, King Fahad Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al Khatib</LastName>
<ForeName>Kasim</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Intensive Care Department, Al-Noor Specialist Hospital, Makkah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Abdulmomen</LastName>
<ForeName>Ahmed</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Critical Care Medicine, King Saud University, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Qushmaq</LastName>
<ForeName>Ismael</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Alfaisal University, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mady</LastName>
<ForeName>Ahmed</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Solaiman</LastName>
<ForeName>Othman</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Intensive Care Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al-Aithan</LastName>
<ForeName>Abdulsalam M</ForeName>
<Initials>AM</Initials>
<Identifier Source="ORCID">0000-0003-2414-4001</Identifier>
<AffiliationInfo><Affiliation>Intensive Care Department, King Abdulaziz Hospital, Al Ahsa, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al-Raddadi</LastName>
<ForeName>Rajaa</ForeName>
<Initials>R</Initials>
<Identifier Source="ORCID">0000-0002-8921-9628</Identifier>
<AffiliationInfo><Affiliation>Department of Family and Community Medicine, King Abdulaziz University Hospital, Ministry of Health, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ragab</LastName>
<ForeName>Ahmed</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Intensive Care Department, King Fahd Hospital, Jeddah, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al Harthy</LastName>
<ForeName>Abdulrahman</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al Qasim</LastName>
<ForeName>Eman</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jose</LastName>
<ForeName>Jesna</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al-Ghamdi</LastName>
<ForeName>Ghassan</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Merson</LastName>
<ForeName>Laura</ForeName>
<Initials>L</Initials>
<Identifier Source="ORCID">0000-0002-4168-1960</Identifier>
<AffiliationInfo><Affiliation>Infectious Diseases Data Observatory, Oxford University, Headiington, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fowler</LastName>
<ForeName>Robert</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Critical Care Medicine and Department of Medicine, Sunnybrook Hospital, Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hayden</LastName>
<ForeName>Frederick G</ForeName>
<Initials>FG</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Division of Infectious Diseases and International Health University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Arabi</LastName>
<ForeName>Yaseen M</ForeName>
<Initials>YM</Initials>
<Identifier Source="ORCID">0000-0001-5735-6241</Identifier>
<AffiliationInfo><Affiliation>Department of intensive care, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016448">Multicenter Study</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>11</Month>
<Day>15</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS One</MedlineTA>
<NlmUniqueID>101285081</NlmUniqueID>
<ISSNLinking>1932-6203</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015897" MajorTopicYN="N">Comorbidity</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016638" MajorTopicYN="N">Critical Illness</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003428" MajorTopicYN="N">Cross Infection</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015199" MajorTopicYN="N">Extracorporeal Membrane Oxygenation</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006282" MajorTopicYN="N">Health Personnel</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017052" MajorTopicYN="N">Hospital Mortality</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017567" MajorTopicYN="N">Karnofsky Performance Status</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D065207" MajorTopicYN="N">Middle East Respiratory Syndrome Coronavirus</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009784" MajorTopicYN="N">Occupational Diseases</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012529" MajorTopicYN="N" Type="Geographic">Saudi Arabia</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015996" MajorTopicYN="N">Survival Rate</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<CoiStatement>The authors have declared that no competing interests exist.</CoiStatement>
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<Day>17</Day>
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Serveur d'exploration MERS

Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.

Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.

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