MersV1, PubMed, Corpus, bibRecord, 000626

An updated roadmap for MERS-CoV research and product development: focus on diagnostics.

Identifieur interne : 000626 ( PubMed/Corpus ); précédent : 000625; suivant : 000627

An updated roadmap for MERS-CoV research and product development: focus on diagnostics.

Auteurs : Cassandra Kelly-Cirino ; Laura T. Mazzola ; Arlene Chua ; Christopher J. Oxenford ; Maria D. Van Kerkhove

Source :

BMJ global health [ 2059-7908 ] ; 2019.

RBID : pubmed:30815285

Abstract

Diagnostics play a central role in the early detection and control of outbreaks and can enable a more nuanced understanding of the disease kinetics and risk factors for the Middle East respiratory syndrome-coronavirus (MERS-CoV), one of the high-priority pathogens identified by the WHO. In this review we identified sources for molecular and serological diagnostic tests used in MERS-CoV detection, case management and outbreak investigations, as well as surveillance for humans and animals (camels), and summarised the performance of currently available tests, diagnostic needs, and associated challenges for diagnostic test development and implementation. A more detailed understanding of the kinetics of infection of MERS-CoV is needed in order to optimise the use of existing assays. Notably, MERS-CoV point-of-care tests are needed in order to optimise supportive care and to minimise transmission risk. However, for new test development, sourcing clinical material continues to be a major challenge to achieving assay validation. Harmonisation and standardisation of laboratory methods are essential for surveillance and for a rapid and effective international response to emerging diseases. Routine external quality assessment, along with well-characterised and up-to-date proficiency panels, would provide insight into MERS-CoV diagnostic performance worldwide. A defined set of Target Product Profiles for diagnostic technologies will be developed by WHO to address these gaps in MERS-CoV outbreak management.

DOI: 10.1136/bmjgh-2018-001105
PubMed: 30815285

Links to Exploration step

pubmed:30815285

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">An updated roadmap for MERS-CoV research and product development: focus on diagnostics.</title>
<author><name sortKey="Kelly Cirino, Cassandra" sort="Kelly Cirino, Cassandra" uniqKey="Kelly Cirino C" first="Cassandra" last="Kelly-Cirino">Cassandra Kelly-Cirino</name>
<affiliation><nlm:affiliation>Emerging Threats Programme, FIND, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mazzola, Laura T" sort="Mazzola, Laura T" uniqKey="Mazzola L" first="Laura T" last="Mazzola">Laura T. Mazzola</name>
<affiliation><nlm:affiliation>Emerging Threats Programme, FIND, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chua, Arlene" sort="Chua, Arlene" uniqKey="Chua A" first="Arlene" last="Chua">Arlene Chua</name>
<affiliation><nlm:affiliation>Department of Information, Evidence and Research, WHO, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Oxenford, Christopher J" sort="Oxenford, Christopher J" uniqKey="Oxenford C" first="Christopher J" last="Oxenford">Christopher J. Oxenford</name>
<affiliation><nlm:affiliation>Health Emergencies Programme, WHO, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name>
<affiliation><nlm:affiliation>Health Emergencies Programme, WHO, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2019">2019</date>
<idno type="RBID">pubmed:30815285</idno>
<idno type="pmid">30815285</idno>
<idno type="doi">10.1136/bmjgh-2018-001105</idno>
<idno type="wicri:Area/PubMed/Corpus">000626</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000626</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">An updated roadmap for MERS-CoV research and product development: focus on diagnostics.</title>
<author><name sortKey="Kelly Cirino, Cassandra" sort="Kelly Cirino, Cassandra" uniqKey="Kelly Cirino C" first="Cassandra" last="Kelly-Cirino">Cassandra Kelly-Cirino</name>
<affiliation><nlm:affiliation>Emerging Threats Programme, FIND, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mazzola, Laura T" sort="Mazzola, Laura T" uniqKey="Mazzola L" first="Laura T" last="Mazzola">Laura T. Mazzola</name>
<affiliation><nlm:affiliation>Emerging Threats Programme, FIND, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chua, Arlene" sort="Chua, Arlene" uniqKey="Chua A" first="Arlene" last="Chua">Arlene Chua</name>
<affiliation><nlm:affiliation>Department of Information, Evidence and Research, WHO, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Oxenford, Christopher J" sort="Oxenford, Christopher J" uniqKey="Oxenford C" first="Christopher J" last="Oxenford">Christopher J. Oxenford</name>
<affiliation><nlm:affiliation>Health Emergencies Programme, WHO, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name>
<affiliation><nlm:affiliation>Health Emergencies Programme, WHO, Geneva, Switzerland.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">BMJ global health</title>
<idno type="ISSN">2059-7908</idno>
<imprint><date when="2019" type="published">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Diagnostics play a central role in the early detection and control of outbreaks and can enable a more nuanced understanding of the disease kinetics and risk factors for the Middle East respiratory syndrome-coronavirus (MERS-CoV), one of the high-priority pathogens identified by the WHO. In this review we identified sources for molecular and serological diagnostic tests used in MERS-CoV detection, case management and outbreak investigations, as well as surveillance for humans and animals (camels), and summarised the performance of currently available tests, diagnostic needs, and associated challenges for diagnostic test development and implementation. A more detailed understanding of the kinetics of infection of MERS-CoV is needed in order to optimise the use of existing assays. Notably, MERS-CoV point-of-care tests are needed in order to optimise supportive care and to minimise transmission risk. However, for new test development, sourcing clinical material continues to be a major challenge to achieving assay validation. Harmonisation and standardisation of laboratory methods are essential for surveillance and for a rapid and effective international response to emerging diseases. Routine external quality assessment, along with well-characterised and up-to-date proficiency panels, would provide insight into MERS-CoV diagnostic performance worldwide. A defined set of Target Product Profiles for diagnostic technologies will be developed by WHO to address these gaps in MERS-CoV outbreak management.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">30815285</PMID>
<DateRevised><Year>2020</Year>
<Month>02</Month>
<Day>25</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Print">2059-7908</ISSN>
<JournalIssue CitedMedium="Print"><Volume>4</Volume>
<Issue>Suppl 2</Issue>
<PubDate><Year>2019</Year>
</PubDate>
</JournalIssue>
<Title>BMJ global health</Title>
<ISOAbbreviation>BMJ Glob Health</ISOAbbreviation>
</Journal>
<ArticleTitle>An updated roadmap for MERS-CoV research and product development: focus on diagnostics.</ArticleTitle>
<Pagination><MedlinePgn>e001105</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1136/bmjgh-2018-001105</ELocationID>
<Abstract><AbstractText>Diagnostics play a central role in the early detection and control of outbreaks and can enable a more nuanced understanding of the disease kinetics and risk factors for the Middle East respiratory syndrome-coronavirus (MERS-CoV), one of the high-priority pathogens identified by the WHO. In this review we identified sources for molecular and serological diagnostic tests used in MERS-CoV detection, case management and outbreak investigations, as well as surveillance for humans and animals (camels), and summarised the performance of currently available tests, diagnostic needs, and associated challenges for diagnostic test development and implementation. A more detailed understanding of the kinetics of infection of MERS-CoV is needed in order to optimise the use of existing assays. Notably, MERS-CoV point-of-care tests are needed in order to optimise supportive care and to minimise transmission risk. However, for new test development, sourcing clinical material continues to be a major challenge to achieving assay validation. Harmonisation and standardisation of laboratory methods are essential for surveillance and for a rapid and effective international response to emerging diseases. Routine external quality assessment, along with well-characterised and up-to-date proficiency panels, would provide insight into MERS-CoV diagnostic performance worldwide. A defined set of Target Product Profiles for diagnostic technologies will be developed by WHO to address these gaps in MERS-CoV outbreak management.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kelly-Cirino</LastName>
<ForeName>Cassandra</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Emerging Threats Programme, FIND, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mazzola</LastName>
<ForeName>Laura T</ForeName>
<Initials>LT</Initials>
<AffiliationInfo><Affiliation>Emerging Threats Programme, FIND, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chua</LastName>
<ForeName>Arlene</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Information, Evidence and Research, WHO, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Medecins Sans Frontières, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Oxenford</LastName>
<ForeName>Christopher J</ForeName>
<Initials>CJ</Initials>
<AffiliationInfo><Affiliation>Health Emergencies Programme, WHO, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Van Kerkhove</LastName>
<ForeName>Maria D</ForeName>
<Initials>MD</Initials>
<AffiliationInfo><Affiliation>Health Emergencies Programme, WHO, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>001</GrantID>
<Agency>World Health Organization</Agency>
<Country>International</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2019</Year>
<Month>02</Month>
<Day>01</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>BMJ Glob Health</MedlineTA>
<NlmUniqueID>101685275</NlmUniqueID>
<ISSNLinking>2059-7908</ISSNLinking>
</MedlineJournalInfo>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">MERS-CoV</Keyword>
<Keyword MajorTopicYN="N">in vitro diagnostics</Keyword>
<Keyword MajorTopicYN="N">middle east respiratory syndrome-coronavirus</Keyword>
<Keyword MajorTopicYN="N">outbreak</Keyword>
</KeywordList>
<CoiStatement>Competing interests: None declared.</CoiStatement>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>08</Month>
<Day>10</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2018</Year>
<Month>10</Month>
<Day>13</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>10</Month>
<Day>23</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2019</Year>
<Month>3</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>3</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>3</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>1</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">30815285</ArticleId>
<ArticleId IdType="doi">10.1136/bmjgh-2018-001105</ArticleId>
<ArticleId IdType="pii">bmjgh-2018-001105</ArticleId>
<ArticleId IdType="pmc">PMC6361340</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Mol Diagn. 2001 Dec;6(4):323-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11774197</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Microbiol. 2004 Jun;12(6):259-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15165603</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2007 Sep;45(9):2965-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17596360</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2009 Sep;47(9):2812-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19571025</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Expert Rev Anti Infect Ther. 2011 Aug;9(8):615-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21819328</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Med. 2012;9(9):e1001306</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22973183</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2012 Sep 27;17(39):null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23041020</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2012 Nov 8;367(19):1814-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Int AIDS Soc. 2012 Oct 09;15(2):17324</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23078767</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2013 Sep;13(9):745-51</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23782859</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2013 Oct;13(10):859-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23933067</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2013 Sep 05;18(36):pii=20574</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24079378</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2014 Jan;52(1):67-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24153118</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2014 Jan;59(1):4-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24286807</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Med. 2013 Nov;10(11):e1001558</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24302890</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2014 Mar;14(3):239-49</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24332389</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2013 Dec 12;18(50):20662</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24342516</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2013 Dec 12;18(50):20659</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24342517</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2014 Feb;14(2):140-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24355866</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Transbound Emerg Dis. 2014 Apr;61(2):105-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24456414</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Vet Diagn Invest. 2014 Mar;26(2):203-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24557752</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2014 Feb 25;5(2):e00884-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24570370</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2014 Jun;60(2):168-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24726679</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pediatr Infect Dis J. 2014 Sep;33(9):904-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24763193</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2014 Apr 29;5(3):e01146-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24781747</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2014 Apr 24;19(16):20781</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24786259</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2014 Nov 1;59(9):1225-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24829216</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Jun;20(6):1049-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24856660</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Jun;20(6):1012-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24857749</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2014 Jun 26;370(26):2499-505</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24896817</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2014 Jun 12;19(23):null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24957744</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Jul;20(7):1231-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24964193</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Aug;20(8):1370-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25062254</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2014 Oct;61(2):275-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25073585</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Aug;20(8):1319-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25075637</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Pathol Lab Med. 2015 May;139(5):636-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25152311</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2014 Aug 28;371(9):828-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25162889</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2015 Feb 1;60(3):369-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25323704</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Dec;20(12):2093-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25425139</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Zoonoses Public Health. 2016 Feb;63(1):1-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25545147</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2015 Apr;53(4):1178-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25631809</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2015 Feb 26;518(7540):477-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25719649</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2015 Oct;53(10):3110-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25762770</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2015 Apr;21(4):699-701</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25811546</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2015 Aug;21(8):1422-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26196891</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2015 Aug;69:81-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26209385</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Microbes Infect. 2015 Apr;4(4):e26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26421268</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2015 Oct 14;18(4):398-401</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26468744</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2015 Oct 16;10(10):e0140125</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26473733</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2016 Feb 15;62(4):477-483</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26565003</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2015 Dec;21(12):2186-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26583829</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2015;20(49):null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26676406</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2016 Jan 1;351(6268):77-81</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26678878</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2016 Feb;75:5-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26702992</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Expert Rev Mol Diagn. 2016;16(4):449-59</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26777725</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Feb;22(2):327-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26814649</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol Sin. 2016 Feb;31(1):85-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26826078</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Drug Discov. 2016 May;15(5):327-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26868298</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Mar;22(3):555-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26889787</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Ann Lab Med. 2016 May;36(3):230-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26915611</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2016 Mar 01;7(2):e00019</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26933050</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Infect Dis. 2016 Jun;47:23-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27062985</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Public Health. 2016 May-Jun;9(3):227-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27095301</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Public Health. 2016 May-Jun;9(3):216-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27106390</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect. 2016 Jul;73(1):82-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27144915</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Microbiol. 2016 Apr 20;7:509</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27148198</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Jul;22(7):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27191188</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2016 Aug;54(8):2104-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27252459</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2016 Jun 03;13:87</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27255185</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Saudi J Biol Sci. 2016 Jul;23(4):507-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27298584</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Jul;22(7):1162-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27314227</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Stud Health Technol Inform. 2016;226:213-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27350507</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Genes. 2016 Dec;52(6):848-854</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27357298</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Essays Biochem. 2016 Jun 30;60(1):111-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27365041</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2016 Jul 7;22(7):701-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27387881</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2016 Sep 3;388(10048):994-1001</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27402381</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2016 Sep 3;388(10048):942-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27402382</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2016 Sep 29;375(13):1303-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27682053</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2016 Oct 3;13(1):163</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27716429</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2016 Dec;54(12):3050-3055</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27733636</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Jundishapur J Microbiol. 2016 Aug 22;9(9):e39132</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27800148</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>World J Clin Pediatr. 2016 Nov 8;5(4):391-396</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27872828</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biosens Bioelectron. 2017 Apr 15;90:187-194</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27894035</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Microbiology. 2017 Mar;163(3):289-296</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28086069</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Diagn Microbiol Infect Dis. 2017 Apr;87(4):320-324</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28104327</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Microbiol. 2017 Jan 09;7:2166</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28119682</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Environ Sci Policy. 2016 Jan;55:1-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28149197</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect. 2017 May;74(5):521-523</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28189714</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet J. 2017 Feb;220:75-79</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28190501</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Iran Red Crescent Med J. 2016 Jun 21;18(11):e23874</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28191331</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2017 Oct 4;35(41):5437-5443</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28216184</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2017 Mar;23(3):550-551</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28221127</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Microbiol. 2017 Mar;55(3):172-182</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28243939</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2017 Mar 2;:null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28262332</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol Methods. 2017 Jun;244:39-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28274744</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2017 Apr;23(4):682-685</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28322710</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2017 Mar 16;22(11):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28333616</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2017 Mar 30;22(13):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28382915</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2017 Jun 1;215(11):1702-1705</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28387845</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Anal Chem. 2017 May 16;89(10):5428-5435</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28394582</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4055-4059</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28396438</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2017 Jun;55(6):1938-1945</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28404682</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Virol. 2017 Apr;23:49-58</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28412285</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bull World Health Organ. 2017 Apr 1;95(4):243</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28479616</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2017 Aug 16;35(35 Pt A):4461-4464</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28576573</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2017 Jun 27;35(30):3780-3788</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28579232</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>One Health. 2017 Mar 10;3:41-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28616502</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Microbes Infect. 2017 Jun 21;6(6):e56</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28634355</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Microbes Infect. 2017 Jun 28;6(6):e60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28655936</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Sci Transl Med. 2017 Jun 28;9(396):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28659436</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antiviral Res. 2017 Aug;144:330-339</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28676301</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thorax. 2018 Mar;73(3):286-289</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28724637</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2017 Sep 13;12(9):e0184718</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28902913</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Public Health. 2018 May - Jun;11(3):331-338</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28993171</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Oncotarget. 2017 Jun 17;8(57):96913-96923</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29228581</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2018 Dec;90(12):1827-1833</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30016543</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antiviral Res. 2018 Nov;159:35-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30236531</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000626 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000626 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    PubMed
   |étape=   Corpus
   |type=    RBID
   |clé=     pubmed:30815285
   |texte=   An updated roadmap for MERS-CoV research and product development: focus on diagnostics.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i   -Sk "pubmed:30815285" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd   \
       | NlmPubMed2Wicri -a MersV1

This area was generated with Dilib version V0.6.33.
Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021

	Serveur d'exploration MERS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration MERS

An updated roadmap for MERS-CoV research and product development: focus on diagnostics.

An updated roadmap for MERS-CoV research and product development: focus on diagnostics.

Source :

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki