MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018.
Identifieur interne : 000546 ( PubMed/Corpus ); précédent : 000545; suivant : 000547MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018.
Auteurs : Amgad A. Elkholy ; Rebecca Grant ; Abdullah Assiri ; Mohamed Elhakim ; Mamunur R. Malik ; Maria D. Van KerkhoveSource :
- Journal of infection and public health [ 1876-035X ] ; 2020.
Abstract
Approximately half of the reported laboratory-confirmed infections of Middle East respiratory syndrome coronavirus (MERS-CoV) have occurred in healthcare settings, and healthcare workers constitute over one third of all secondary infections. This study aimed to describe secondary cases of MERS-CoV infection among healthcare workers and to identify risk factors for death.
DOI: 10.1016/j.jiph.2019.04.011
PubMed: 31056437
Links to Exploration step
pubmed:31056437Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018.</title><author><name sortKey="Elkholy, Amgad A" sort="Elkholy, Amgad A" uniqKey="Elkholy A" first="Amgad A" last="Elkholy">Amgad A. Elkholy</name><affiliation><nlm:affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Grant, Rebecca" sort="Grant, Rebecca" uniqKey="Grant R" first="Rebecca" last="Grant">Rebecca Grant</name><affiliation><nlm:affiliation>Centre for Global Health, Institut Pasteur, Paris, France; Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Assiri, Abdullah" sort="Assiri, Abdullah" uniqKey="Assiri A" first="Abdullah" last="Assiri">Abdullah Assiri</name><affiliation><nlm:affiliation>Ministry of Health, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Elhakim, Mohamed" sort="Elhakim, Mohamed" uniqKey="Elhakim M" first="Mohamed" last="Elhakim">Mohamed Elhakim</name><affiliation><nlm:affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Malik, Mamunur R" sort="Malik, Mamunur R" uniqKey="Malik M" first="Mamunur R" last="Malik">Mamunur R. Malik</name><affiliation><nlm:affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name><affiliation><nlm:affiliation>Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland. Electronic address: vankerkhovem@who.int.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:31056437</idno><idno type="pmid">31056437</idno><idno type="doi">10.1016/j.jiph.2019.04.011</idno><idno type="wicri:Area/PubMed/Corpus">000546</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000546</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018.</title><author><name sortKey="Elkholy, Amgad A" sort="Elkholy, Amgad A" uniqKey="Elkholy A" first="Amgad A" last="Elkholy">Amgad A. Elkholy</name><affiliation><nlm:affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Grant, Rebecca" sort="Grant, Rebecca" uniqKey="Grant R" first="Rebecca" last="Grant">Rebecca Grant</name><affiliation><nlm:affiliation>Centre for Global Health, Institut Pasteur, Paris, France; Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Assiri, Abdullah" sort="Assiri, Abdullah" uniqKey="Assiri A" first="Abdullah" last="Assiri">Abdullah Assiri</name><affiliation><nlm:affiliation>Ministry of Health, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Elhakim, Mohamed" sort="Elhakim, Mohamed" uniqKey="Elhakim M" first="Mohamed" last="Elhakim">Mohamed Elhakim</name><affiliation><nlm:affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Malik, Mamunur R" sort="Malik, Mamunur R" uniqKey="Malik M" first="Mamunur R" last="Malik">Mamunur R. Malik</name><affiliation><nlm:affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name><affiliation><nlm:affiliation>Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland. Electronic address: vankerkhovem@who.int.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of infection and public health</title><idno type="eISSN">1876-035X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Approximately half of the reported laboratory-confirmed infections of Middle East respiratory syndrome coronavirus (MERS-CoV) have occurred in healthcare settings, and healthcare workers constitute over one third of all secondary infections. This study aimed to describe secondary cases of MERS-CoV infection among healthcare workers and to identify risk factors for death.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">31056437</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1876-035X</ISSN><JournalIssue CitedMedium="Internet"><Volume>13</Volume><Issue>3</Issue><PubDate><Year>2020</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Journal of infection and public health</Title><ISOAbbreviation>J Infect Public Health</ISOAbbreviation></Journal><ArticleTitle>MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018.</ArticleTitle><Pagination><MedlinePgn>418-422</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1876-0341(19)30144-3</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jiph.2019.04.011</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Approximately half of the reported laboratory-confirmed infections of Middle East respiratory syndrome coronavirus (MERS-CoV) have occurred in healthcare settings, and healthcare workers constitute over one third of all secondary infections. This study aimed to describe secondary cases of MERS-CoV infection among healthcare workers and to identify risk factors for death.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A retrospective analysis was conducted on epidemiological data of laboratory-confirmed MERS-CoV cases reported to the World Health Organization from September 2012 to 2 June 2018. We compared all secondary cases among healthcare workers with secondary cases among non-healthcare workers. Multivariable logistic regression identified risk factors for death.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Of the 2223 laboratory-confirmed MERS-CoV cases reported to WHO, 415 were healthcare workers and 1783 were non-healthcare workers. Compared with non-healthcare workers cases, healthcare workers cases were younger (P < 0.001), more likely to be female (P < 0.001), non-nationals (P < 0.001) and asymptomatic (P < 0.001), and have fewer comorbidities (P < 0.001) and higher rates of survival (P < 0.001). Year of infection (2013-2018) and having no comorbidities were independent protective factors against death among secondary healthcare workers cases.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Being able to protect healthcare workers from high threat respiratory pathogens, such as MERS-CoV is important for being able to reduce secondary transmission of MERS-CoV in healthcare-associated outbreaks. By extension, reducing infection in healthcare workers improves continuity of care for all patients within healthcare facilities.</AbstractText><CopyrightInformation>Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Elkholy</LastName><ForeName>Amgad A</ForeName><Initials>AA</Initials><AffiliationInfo><Affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grant</LastName><ForeName>Rebecca</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Centre for Global Health, Institut Pasteur, Paris, France; Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Assiri</LastName><ForeName>Abdullah</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Ministry of Health, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Elhakim</LastName><ForeName>Mohamed</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Malik</LastName><ForeName>Mamunur R</ForeName><Initials>MR</Initials><AffiliationInfo><Affiliation>Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Van Kerkhove</LastName><ForeName>Maria D</ForeName><Initials>MD</Initials><AffiliationInfo><Affiliation>Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland. Electronic address: vankerkhovem@who.int.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>001</GrantID><Acronym>WHO_</Acronym><Agency>World Health Organization</Agency><Country>International</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>05</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Infect Public Health</MedlineTA><NlmUniqueID>101487384</NlmUniqueID><ISSNLinking>1876-0341</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Infection prevention and control</Keyword><Keyword MajorTopicYN="N">MERS-CoV</Keyword><Keyword MajorTopicYN="N">Nosocomial infection</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>08</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>04</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>04</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>5</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>5</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>5</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31056437</ArticleId><ArticleId IdType="pii">S1876-0341(19)30144-3</ArticleId><ArticleId IdType="doi">10.1016/j.jiph.2019.04.011</ArticleId><ArticleId IdType="pmc">PMC7102841</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Int J Occup Environ Health. 2004 Oct-Dec;10(4):421-7</Citation><ArticleIdList><ArticleId IdType="pubmed">15702757</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Clin Infect Dis. 2017 May 15;64(10):1457-1458</Citation><ArticleIdList><ArticleId IdType="pubmed">28444154</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Epidemiol Health. 2015 Jul 21;37:e2015033</Citation><ArticleIdList><ArticleId IdType="pubmed">26212508</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Lancet. 2013 Jun 29;381(9885):2265-72</Citation><ArticleIdList><ArticleId IdType="pubmed">23727167</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Int J Infect Dis. 2014 Dec;29:307-8</Citation><ArticleIdList><ArticleId IdType="pubmed">25448335</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Clin Infect Dis. 2015 Feb 1;60(3):369-77</Citation><ArticleIdList><ArticleId IdType="pubmed">25323704</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>East Mediterr Health J. 2013;19 Suppl 1:S12-8</Citation><ArticleIdList><ArticleId IdType="pubmed">23888790</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Crit Care Med. 2017 Oct;45(10):1683-1695</Citation><ArticleIdList><ArticleId IdType="pubmed">28787295</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Emerg Infect Dis. 2015 Nov;21(11):1981-8</Citation><ArticleIdList><ArticleId IdType="pubmed">26484549</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>PLoS Curr. 2013 Nov 12;5:</Citation><ArticleIdList><ArticleId IdType="pubmed">24270606</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Am J Infect Control. 2018 Feb;46(2):165-168</Citation><ArticleIdList><ArticleId IdType="pubmed">28958446</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Clin Infect Dis. 2016 Aug 1;63(3):363-9</Citation><ArticleIdList><ArticleId IdType="pubmed">27090992</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Emerg Infect Dis. 2016 Jul;22(7):1162-8</Citation><ArticleIdList><ArticleId IdType="pubmed">27314227</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2012 Nov 8;367(19):1814-20</Citation><ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2017 Feb 9;376(6):584-594</Citation><ArticleIdList><ArticleId IdType="pubmed">28177862</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Euro Surveill. 2015 Jun 25;20(25):1-6</Citation><ArticleIdList><ArticleId IdType="pubmed">26132766</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Euro Surveill. 2013 Sep 19;18(38):</Citation><ArticleIdList><ArticleId IdType="pubmed">24084338</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Int J Infect Dis. 2013 Sep;17(9):e668-72</Citation><ArticleIdList><ArticleId IdType="pubmed">23916548</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Clin Infect Dis. 2015 Mar 15;60(6):973-4</Citation><ArticleIdList><ArticleId IdType="pubmed">25516193</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2013 Aug 1;369(5):407-16</Citation><ArticleIdList><ArticleId IdType="pubmed">23782161</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Clin Infect Dis. 2014 Nov 1;59(9):1225-33</Citation><ArticleIdList><ArticleId IdType="pubmed">24829216</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Infect. 2017 Oct;75(4):378-379</Citation><ArticleIdList><ArticleId IdType="pubmed">28606432</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Clin Infect Dis. 2016 Mar 15;62(6):755-60</Citation><ArticleIdList><ArticleId IdType="pubmed">26679623</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000546 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000546 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:31056437
|texte= MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:31056437" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |