Focus on Middle East respiratory syndrome coronavirus (MERS-CoV).
Identifieur interne : 000362 ( PubMed/Corpus ); précédent : 000361; suivant : 000363Focus on Middle East respiratory syndrome coronavirus (MERS-CoV).
Auteurs : A. Bleibtreu ; M. Bertine ; C. Bertin ; N. Houhou-Fidouh ; B. VisseauxSource :
- Medecine et maladies infectieuses [ 1769-6690 ] ; 2019.
Abstract
Since the first case of human infection by the Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia in June 2012, more than 2260 cases of confirmed MERS-CoV infection and 803 related deaths have been reported since the 16th of October 2018. The vast majority of these cases (71%) were reported in Saudi Arabia but the epidemic has now spread to 27 countries and has not ceased 6 years later, unlike SARS-CoV that disappeared a little less than 2 years after emerging. Due to the high fatality rate observed in MERS-CoV infected patients (36%), much effort has been put into understanding the origin and pathophysiology of this novel coronavirus to prevent it from becoming endemic in humans. This review focuses in particular on the origin, epidemiology and clinical manifestations of MERS-CoV, as well as the diagnosis and treatment of infected patients. The experience gained over recent years on how to manage the different risks related to this kind of epidemic will be key to being prepared for future outbreaks of communicable disease.
DOI: 10.1016/j.medmal.2019.10.004
PubMed: 31727466
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Bertin</name><affiliation><nlm:affiliation>Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Houhou Fidouh, N" sort="Houhou Fidouh, N" uniqKey="Houhou Fidouh N" first="N" last="Houhou-Fidouh">N. Houhou-Fidouh</name><affiliation><nlm:affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Visseaux, B" sort="Visseaux, B" uniqKey="Visseaux B" first="B" last="Visseaux">B. Visseaux</name><affiliation><nlm:affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France. Electronic address: benoit.visseaux@aphp.fr.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2019">2019</date><idno type="RBID">pubmed:31727466</idno><idno type="pmid">31727466</idno><idno type="doi">10.1016/j.medmal.2019.10.004</idno><idno type="wicri:Area/PubMed/Corpus">000362</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000362</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Focus on Middle East respiratory syndrome coronavirus (MERS-CoV).</title><author><name sortKey="Bleibtreu, A" sort="Bleibtreu, A" uniqKey="Bleibtreu A" first="A" last="Bleibtreu">A. Bleibtreu</name><affiliation><nlm:affiliation>Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Bertine, M" sort="Bertine, M" uniqKey="Bertine M" first="M" last="Bertine">M. Bertine</name><affiliation><nlm:affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Bertin, C" sort="Bertin, C" uniqKey="Bertin C" first="C" last="Bertin">C. Bertin</name><affiliation><nlm:affiliation>Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Houhou Fidouh, N" sort="Houhou Fidouh, N" uniqKey="Houhou Fidouh N" first="N" last="Houhou-Fidouh">N. Houhou-Fidouh</name><affiliation><nlm:affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Visseaux, B" sort="Visseaux, B" uniqKey="Visseaux B" first="B" last="Visseaux">B. Visseaux</name><affiliation><nlm:affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France. Electronic address: benoit.visseaux@aphp.fr.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Medecine et maladies infectieuses</title><idno type="eISSN">1769-6690</idno><imprint><date when="2019" type="published">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Since the first case of human infection by the Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia in June 2012, more than 2260 cases of confirmed MERS-CoV infection and 803 related deaths have been reported since the 16th of October 2018. The vast majority of these cases (71%) were reported in Saudi Arabia but the epidemic has now spread to 27 countries and has not ceased 6 years later, unlike SARS-CoV that disappeared a little less than 2 years after emerging. Due to the high fatality rate observed in MERS-CoV infected patients (36%), much effort has been put into understanding the origin and pathophysiology of this novel coronavirus to prevent it from becoming endemic in humans. This review focuses in particular on the origin, epidemiology and clinical manifestations of MERS-CoV, as well as the diagnosis and treatment of infected patients. The experience gained over recent years on how to manage the different risks related to this kind of epidemic will be key to being prepared for future outbreaks of communicable disease.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">31727466</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>09</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1769-6690</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2019</Year><Month>Nov</Month><Day>11</Day></PubDate></JournalIssue><Title>Medecine et maladies infectieuses</Title><ISOAbbreviation>Med Mal Infect</ISOAbbreviation></Journal><ArticleTitle>Focus on Middle East respiratory syndrome coronavirus (MERS-CoV).</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">S0399-077X(19)31054-6</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.medmal.2019.10.004</ELocationID><Abstract><AbstractText>Since the first case of human infection by the Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia in June 2012, more than 2260 cases of confirmed MERS-CoV infection and 803 related deaths have been reported since the 16th of October 2018. The vast majority of these cases (71%) were reported in Saudi Arabia but the epidemic has now spread to 27 countries and has not ceased 6 years later, unlike SARS-CoV that disappeared a little less than 2 years after emerging. Due to the high fatality rate observed in MERS-CoV infected patients (36%), much effort has been put into understanding the origin and pathophysiology of this novel coronavirus to prevent it from becoming endemic in humans. This review focuses in particular on the origin, epidemiology and clinical manifestations of MERS-CoV, as well as the diagnosis and treatment of infected patients. The experience gained over recent years on how to manage the different risks related to this kind of epidemic will be key to being prepared for future outbreaks of communicable disease.</AbstractText><CopyrightInformation>Copyright © 2019 Elsevier Masson SAS. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bleibtreu</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bertine</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bertin</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Houhou-Fidouh</LastName><ForeName>N</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Visseaux</LastName><ForeName>B</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP-HP, Paris, France. 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