Asymptomatic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection: Extent and implications for infection control: A systematic review.
Identifieur interne : 002986 ( PubMed/Checkpoint ); précédent : 002985; suivant : 002987Asymptomatic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection: Extent and implications for infection control: A systematic review.
Auteurs : Jaffar A. Al-Tawfiq [États-Unis] ; Philippe Gautret [France]Source :
- Travel medicine and infectious disease [ 1873-0442 ]
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- epidemiology : Asymptomatic Infections, Coronavirus Infections, Cross Infection.
- transmission : Coronavirus Infections.
- Animals, Disease Outbreaks, Humans, Infection Control, Middle East Respiratory Syndrome Coronavirus, Travel.
Abstract
The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) emerged in 2012 and attracted an international attention as the virus caused multiple healthcare associated outbreaks. There are reports of the role of asymptomatic individuals in the transmission of MERS-CoV, however, the exact role is not known.
DOI: 10.1016/j.tmaid.2018.12.003
PubMed: 30550839
Affiliations:
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There are reports of the role of asymptomatic individuals in the transmission of MERS-CoV, however, the exact role is not known.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30550839</PMID><DateCompleted><Year>2019</Year><Month>04</Month><Day>16</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-0442</ISSN><JournalIssue CitedMedium="Internet"><Volume>27</Volume><PubDate><MedlineDate>2019 Jan - Feb</MedlineDate></PubDate></JournalIssue><Title>Travel medicine and infectious disease</Title><ISOAbbreviation>Travel Med Infect Dis</ISOAbbreviation></Journal><ArticleTitle>Asymptomatic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection: Extent and implications for infection control: A systematic review.</ArticleTitle><Pagination><MedlinePgn>27-32</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1477-8939(18)30343-0</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.tmaid.2018.12.003</ELocationID><Abstract><AbstractText Label="BACKGROUND">The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) emerged in 2012 and attracted an international attention as the virus caused multiple healthcare associated outbreaks. There are reports of the role of asymptomatic individuals in the transmission of MERS-CoV, however, the exact role is not known.</AbstractText><AbstractText Label="METHOD">The MEDLINE/PubMed and Scopus databases were searched for relevant papers published till August 2018 describing asymptomatic MERS-CoV infection.</AbstractText><AbstractText Label="RESULTS">A total of 10 papers were retrieved and included in the final analysis and review. The extent of asymptomatic MERS infection had increased with change in the policy of testing asymptomatic contacts. In early cases in April 2012-October 2013, 12.5% were asymptomatic among 144 PCR laboratory-confirmed MERS-CoV cases while in 2014 the proportion rose to 25.1% among 255 confirmed cases. The proportion of asymptomatic cases reported among pediatric confirmed MERS-CoV cases were higher (41.9%-81.8%). Overall, the detection rate of MERS infection among asymptomatic contacts was 1-3.9% in studies included in this review. Asymptomatic individuals were less likely to have underlying condition compared to fatal cases. Of particular interest is that most of the identified pediatric cases were asymptomatic with no clear explanation.</AbstractText><AbstractText Label="CONCLUSIONS">The proportion of asymptomatic MERS cases were detected with increasing frequency as the disease progressed overtime. Those patients were less likely to have comorbid disease and may contribute to the transmission of the virus.</AbstractText><CopyrightInformation>Copyright © 2018 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Al-Tawfiq</LastName><ForeName>Jaffar A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Specialty Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; Indiana University School of Medicine, Indianapolis, IN, USA; Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: jaffar.tawfiq@jhah.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gautret</LastName><ForeName>Philippe</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Aix Marseille Univ, Institut de Recherche pour le Développement (IRD), Assistance Publique-Hôpitaux de Marseille (AP-HM), Service de Santé des Armées (SSA), Microbes Vecteurs Infections Tropicales et Méditerranéennes (VITROME), Institut Hospitalo-Universitaire-Méditerranée Infection (IHU-Méditerranée Infection), Marseille, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D000078182">Systematic Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>12</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Travel Med Infect 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Al-Tawfiq</name></region></country><country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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