[Synthesis of modified oligodeoxyribonucleotides containing 9-(2'-amino-2'-deoxy-beta-D-arabinofuranosyl)adenine].
Identifieur interne : 002560 ( PubMed/Checkpoint ); précédent : 002559; suivant : 002561[Synthesis of modified oligodeoxyribonucleotides containing 9-(2'-amino-2'-deoxy-beta-D-arabinofuranosyl)adenine].
Auteurs : E M Zubin ; S I Antsypovich ; T S Oretskaya ; E A Romanova ; E M Volkov ; V N Tashlitski ; Z A ShabarovaSource :
- Bioorganicheskaia khimiia [ 0132-3423 ] ; 1997.
Descripteurs français
- KwdFr :
- MESH :
- synthèse chimique : Oligodésoxyribonucléotides.
- ADN, Acylation, Amines, Anhydrides, Oligodésoxyribonucléotides, Vidarabine.
English descriptors
- KwdEn :
- MESH :
- chemical , chemical synthesis : Oligodeoxyribonucleotides.
- chemical , chemistry : Amines, Anhydrides, DNA, Oligodeoxyribonucleotides, Vidarabine.
- Acylation.
Abstract
A method for preparing a modified derivative of 2'-amino-2'-deoxy-arabino-adenosine ready for directed insertion into an oligonucleotide chain during solid-phase synthesis was elaborated. A series of the title oligonucleotides (6-25-mers) containing a 2'-amino-2'-deoxy-arabino-adenosine fragment were prepared. A high reactivity of the 2'-amino group during the acylation with carboxylic acid anhydrides was demonstrated. It was shown that the insertion of the modified fragments into oligonucleotides did not inhibit the formation of the DNA duplex.
PubMed: 9490617
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:9490617Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Synthesis of modified oligodeoxyribonucleotides containing 9-(2'-amino-2'-deoxy-beta-D-arabinofuranosyl)adenine].</title><author><name sortKey="Zubin, E M" sort="Zubin, E M" uniqKey="Zubin E" first="E M" last="Zubin">E M Zubin</name></author><author><name sortKey="Antsypovich, S I" sort="Antsypovich, S I" uniqKey="Antsypovich S" first="S I" last="Antsypovich">S I Antsypovich</name></author><author><name sortKey="Oretskaya, T S" sort="Oretskaya, T S" uniqKey="Oretskaya T" first="T S" last="Oretskaya">T S Oretskaya</name></author><author><name sortKey="Romanova, E A" sort="Romanova, E A" uniqKey="Romanova E" first="E A" last="Romanova">E A Romanova</name></author><author><name sortKey="Volkov, E M" sort="Volkov, E M" uniqKey="Volkov E" first="E M" last="Volkov">E M Volkov</name></author><author><name sortKey="Tashlitski, V N" sort="Tashlitski, V N" uniqKey="Tashlitski V" first="V N" last="Tashlitski">V N Tashlitski</name></author><author><name sortKey="Shabarova, Z A" sort="Shabarova, Z A" uniqKey="Shabarova Z" first="Z A" last="Shabarova">Z A Shabarova</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1997">1997</date><idno type="RBID">pubmed:9490617</idno><idno type="pmid">9490617</idno><idno type="wicri:Area/PubMed/Corpus">002702</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002702</idno><idno type="wicri:Area/PubMed/Curation">002702</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002702</idno><idno type="wicri:Area/PubMed/Checkpoint">002560</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002560</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Synthesis of modified oligodeoxyribonucleotides containing 9-(2'-amino-2'-deoxy-beta-D-arabinofuranosyl)adenine].</title><author><name sortKey="Zubin, E M" sort="Zubin, E M" uniqKey="Zubin E" first="E M" last="Zubin">E M Zubin</name></author><author><name sortKey="Antsypovich, S I" sort="Antsypovich, S I" uniqKey="Antsypovich S" first="S I" last="Antsypovich">S I Antsypovich</name></author><author><name sortKey="Oretskaya, T S" sort="Oretskaya, T S" uniqKey="Oretskaya T" first="T S" last="Oretskaya">T S Oretskaya</name></author><author><name sortKey="Romanova, E A" sort="Romanova, E A" uniqKey="Romanova E" first="E A" last="Romanova">E A Romanova</name></author><author><name sortKey="Volkov, E M" sort="Volkov, E M" uniqKey="Volkov E" first="E M" last="Volkov">E M Volkov</name></author><author><name sortKey="Tashlitski, V N" sort="Tashlitski, V N" uniqKey="Tashlitski V" first="V N" last="Tashlitski">V N Tashlitski</name></author><author><name sortKey="Shabarova, Z A" sort="Shabarova, Z A" uniqKey="Shabarova Z" first="Z A" last="Shabarova">Z A Shabarova</name></author></analytic><series><title level="j">Bioorganicheskaia khimiia</title><idno type="ISSN">0132-3423</idno><imprint><date when="1997" type="published">1997</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acylation</term><term>Amines (chemistry)</term><term>Anhydrides (chemistry)</term><term>DNA (chemistry)</term><term>Oligodeoxyribonucleotides (chemical synthesis)</term><term>Oligodeoxyribonucleotides (chemistry)</term><term>Vidarabine (chemistry)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ADN ()</term><term>Acylation</term><term>Amines ()</term><term>Anhydrides ()</term><term>Oligodésoxyribonucléotides ()</term><term>Oligodésoxyribonucléotides (synthèse chimique)</term><term>Vidarabine ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemical synthesis" xml:lang="en"><term>Oligodeoxyribonucleotides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Amines</term><term>Anhydrides</term><term>DNA</term><term>Oligodeoxyribonucleotides</term><term>Vidarabine</term></keywords><keywords scheme="MESH" qualifier="synthèse chimique" xml:lang="fr"><term>Oligodésoxyribonucléotides</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Acylation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>ADN</term><term>Acylation</term><term>Amines</term><term>Anhydrides</term><term>Oligodésoxyribonucléotides</term><term>Vidarabine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A method for preparing a modified derivative of 2'-amino-2'-deoxy-arabino-adenosine ready for directed insertion into an oligonucleotide chain during solid-phase synthesis was elaborated. A series of the title oligonucleotides (6-25-mers) containing a 2'-amino-2'-deoxy-arabino-adenosine fragment were prepared. A high reactivity of the 2'-amino group during the acylation with carboxylic acid anhydrides was demonstrated. It was shown that the insertion of the modified fragments into oligonucleotides did not inhibit the formation of the DNA duplex.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">9490617</PMID><DateCompleted><Year>1998</Year><Month>03</Month><Day>03</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0132-3423</ISSN><JournalIssue CitedMedium="Print"><Volume>23</Volume><Issue>10</Issue><PubDate><Year>1997</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Bioorganicheskaia khimiia</Title><ISOAbbreviation>Bioorg. Khim.</ISOAbbreviation></Journal><ArticleTitle>[Synthesis of modified oligodeoxyribonucleotides containing 9-(2'-amino-2'-deoxy-beta-D-arabinofuranosyl)adenine].</ArticleTitle><Pagination><MedlinePgn>809-16</MedlinePgn></Pagination><Abstract><AbstractText>A method for preparing a modified derivative of 2'-amino-2'-deoxy-arabino-adenosine ready for directed insertion into an oligonucleotide chain during solid-phase synthesis was elaborated. A series of the title oligonucleotides (6-25-mers) containing a 2'-amino-2'-deoxy-arabino-adenosine fragment were prepared. A high reactivity of the 2'-amino group during the acylation with carboxylic acid anhydrides was demonstrated. It was shown that the insertion of the modified fragments into oligonucleotides did not inhibit the formation of the DNA duplex.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zubin</LastName><ForeName>E M</ForeName><Initials>EM</Initials></Author><Author ValidYN="Y"><LastName>Antsypovich</LastName><ForeName>S I</ForeName><Initials>SI</Initials></Author><Author ValidYN="Y"><LastName>Oretskaya</LastName><ForeName>T S</ForeName><Initials>TS</Initials></Author><Author ValidYN="Y"><LastName>Romanova</LastName><ForeName>E A</ForeName><Initials>EA</Initials></Author><Author ValidYN="Y"><LastName>Volkov</LastName><ForeName>E M</ForeName><Initials>EM</Initials></Author><Author ValidYN="Y"><LastName>Tashlitskiĭ</LastName><ForeName>V N</ForeName><Initials>VN</Initials></Author><Author ValidYN="Y"><LastName>Shabarova</LastName><ForeName>Z A</ForeName><Initials>ZA</Initials></Author></AuthorList><Language>rus</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Sintez modifitsirovannykh oligodezoksiribonukleotidov, soderzhashchikh 9-(2'-amino-2'-dezoksi-beta-D-arabinofuranozil)adenin.</VernacularTitle></Article><MedlineJournalInfo><Country>Russia (Federation)</Country><MedlineTA>Bioorg Khim</MedlineTA><NlmUniqueID>7804941</NlmUniqueID><ISSNLinking>0132-3423</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000588">Amines</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000812">Anhydrides</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009838">Oligodeoxyribonucleotides</NameOfSubstance></Chemical><Chemical><RegistryNumber>9007-49-2</RegistryNumber><NameOfSubstance UI="D004247">DNA</NameOfSubstance></Chemical><Chemical><RegistryNumber>FA2DM6879K</RegistryNumber><NameOfSubstance UI="D014740">Vidarabine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000215" MajorTopicYN="N">Acylation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000588" MajorTopicYN="N">Amines</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000812" MajorTopicYN="N">Anhydrides</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004247" MajorTopicYN="N">DNA</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009838" MajorTopicYN="N">Oligodeoxyribonucleotides</DescriptorName><QualifierName UI="Q000138" MajorTopicYN="Y">chemical synthesis</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014740" MajorTopicYN="N">Vidarabine</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1998</Year><Month>3</Month><Day>7</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1998</Year><Month>3</Month><Day>7</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1998</Year><Month>3</Month><Day>7</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">9490617</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Antsypovich, S I" sort="Antsypovich, S I" uniqKey="Antsypovich S" first="S I" last="Antsypovich">S I Antsypovich</name><name sortKey="Oretskaya, T S" sort="Oretskaya, T S" uniqKey="Oretskaya T" first="T S" last="Oretskaya">T S Oretskaya</name><name sortKey="Romanova, E A" sort="Romanova, E A" uniqKey="Romanova E" first="E A" last="Romanova">E A Romanova</name><name sortKey="Shabarova, Z A" sort="Shabarova, Z A" uniqKey="Shabarova Z" first="Z A" last="Shabarova">Z A Shabarova</name><name sortKey="Tashlitski, V N" sort="Tashlitski, V N" uniqKey="Tashlitski V" first="V N" last="Tashlitski">V N Tashlitski</name><name sortKey="Volkov, E M" sort="Volkov, E M" uniqKey="Volkov E" first="E M" last="Volkov">E M Volkov</name><name sortKey="Zubin, E M" sort="Zubin, E M" uniqKey="Zubin E" first="E M" last="Zubin">E M Zubin</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002560 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 002560 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:9490617
|texte= [Synthesis of modified oligodeoxyribonucleotides containing 9-(2'-amino-2'-deoxy-beta-D-arabinofuranosyl)adenine].
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:9490617" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |