MersV1, PubMed, Checkpoint, bibRecord, 002477

Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.

Identifieur interne : 002477 ( PubMed/Checkpoint ); précédent : 002476; suivant : 002478

Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.

Auteurs : J P Belk [États-Unis] ; F. He ; A. Jacobson

Source :

RNA (New York, N.Y.) [ 1355-8382 ] ; 1999.

RBID : pubmed:10445880

Descripteurs français

KwdFr :
- ARN messager (métabolisme), ARN ribosomique (génétique), ARN ribosomique (métabolisme), Biosynthèse des protéines, Clonage moléculaire, Division cellulaire (génétique), Données de séquences moléculaires, Facteurs temps, Galactose (pharmacologie), Gènes dominants, Inhibiteurs de la synthèse protéique (métabolisme), Modèles génétiques, Polyribosomes (métabolisme), Protéines de Saccharomyces cerevisiae, Protéines de liaison à l'ARN, Protéines fongiques (génétique), Protéines fongiques (métabolisme), Protéines fongiques (physiologie), RNA helicases (métabolisme), Régulation de l'expression des gènes fongiques, Saccharomyces cerevisiae (métabolisme), Similitude de séquences d'acides aminés, Séquence d'acides aminés, Technique de Northern.
MESH :
- génétique : ARN ribosomique, Division cellulaire, Protéines fongiques.
- métabolisme : ARN messager, ARN ribosomique, Inhibiteurs de la synthèse protéique, Polyribosomes, Protéines fongiques, RNA helicases, Saccharomyces cerevisiae.
- pharmacologie : Galactose.
- physiologie : Protéines fongiques.
- Biosynthèse des protéines, Clonage moléculaire, Données de séquences moléculaires, Facteurs temps, Gènes dominants, Modèles génétiques, Protéines de Saccharomyces cerevisiae, Protéines de liaison à l'ARN, Régulation de l'expression des gènes fongiques, Similitude de séquences d'acides aminés, Séquence d'acides aminés, Technique de Northern.

English descriptors

KwdEn :
- Amino Acid Sequence, Blotting, Northern, Cell Division (genetics), Cloning, Molecular, Fungal Proteins (genetics), Fungal Proteins (metabolism), Fungal Proteins (physiology), Galactose (pharmacology), Gene Expression Regulation, Fungal, Genes, Dominant, Models, Genetic, Molecular Sequence Data, Polyribosomes (metabolism), Protein Biosynthesis, Protein Synthesis Inhibitors (metabolism), RNA Helicases (metabolism), RNA, Messenger (metabolism), RNA, Ribosomal (genetics), RNA, Ribosomal (metabolism), RNA-Binding Proteins, Saccharomyces cerevisiae (metabolism), Saccharomyces cerevisiae Proteins, Sequence Homology, Amino Acid, Time Factors.
MESH :
- chemical , genetics : Fungal Proteins, RNA, Ribosomal.
- genetics : Cell Division.
- chemical , metabolism : Fungal Proteins, Polyribosomes, Protein Synthesis Inhibitors, RNA Helicases, RNA, Messenger, RNA, Ribosomal, Saccharomyces cerevisiae.
- chemical , pharmacology : Galactose.
- chemical , physiology : Fungal Proteins.
- Amino Acid Sequence, Blotting, Northern, Cloning, Molecular, Gene Expression Regulation, Fungal, Genes, Dominant, Models, Genetic, Molecular Sequence Data, Protein Biosynthesis, RNA-Binding Proteins, Saccharomyces cerevisiae Proteins, Sequence Homology, Amino Acid, Time Factors.

Abstract

The yeast NMD3 gene was identified in a two-hybrid screen using the nonsense-mediated mRNA decay factor, Upf1p, as bait. NMD3 was shown to encode an essential, highly conserved protein that associated principally with free 60S ribosomal subunits. Overexpression of a truncated form of Nmd3p, lacking 100 C-terminal amino acids and most of its Upf1p-interacting domain, had dominant-negative effects on both cell growth and protein synthesis and promoted the formation of polyribosome half-mers. These effects were eliminated by truncation of an additional 100 amino acids from Nmd3p. Overexpression of the nmd3delta100 allele also led to increased synthesis and destabilization of some ribosomal protein mRNAs, and increased synthesis and altered processing of 35S pre-rRNA. Our data suggest that Nmd3p has a role in the formation, function, or maintenance of the 60S ribosomal subunit and may provide a link for Upf1p to 80S monosomes.

DOI: 10.1017/s1355838299990027
PubMed: 10445880

Affiliations:

États-Unis

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 002623
to stream PubMed, to step Curation: 002623

Links to Exploration step

pubmed:10445880

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.</title>
<author><name sortKey="Belk, J P" sort="Belk, J P" uniqKey="Belk J" first="J P" last="Belk">J P Belk</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655-0122, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655-0122</wicri:regionArea>
<wicri:noRegion>Worcester 01655-0122</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="He, F" sort="He, F" uniqKey="He F" first="F" last="He">F. He</name>
</author>
<author><name sortKey="Jacobson, A" sort="Jacobson, A" uniqKey="Jacobson A" first="A" last="Jacobson">A. Jacobson</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1999">1999</date>
<idno type="RBID">pubmed:10445880</idno>
<idno type="pmid">10445880</idno>
<idno type="doi">10.1017/s1355838299990027</idno>
<idno type="wicri:Area/PubMed/Corpus">002623</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002623</idno>
<idno type="wicri:Area/PubMed/Curation">002623</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002623</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002477</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002477</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.</title>
<author><name sortKey="Belk, J P" sort="Belk, J P" uniqKey="Belk J" first="J P" last="Belk">J P Belk</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655-0122, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655-0122</wicri:regionArea>
<wicri:noRegion>Worcester 01655-0122</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="He, F" sort="He, F" uniqKey="He F" first="F" last="He">F. He</name>
</author>
<author><name sortKey="Jacobson, A" sort="Jacobson, A" uniqKey="Jacobson A" first="A" last="Jacobson">A. Jacobson</name>
</author>
</analytic>
<series><title level="j">RNA (New York, N.Y.)</title>
<idno type="ISSN">1355-8382</idno>
<imprint><date when="1999" type="published">1999</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence</term>
<term>Blotting, Northern</term>
<term>Cell Division (genetics)</term>
<term>Cloning, Molecular</term>
<term>Fungal Proteins (genetics)</term>
<term>Fungal Proteins (metabolism)</term>
<term>Fungal Proteins (physiology)</term>
<term>Galactose (pharmacology)</term>
<term>Gene Expression Regulation, Fungal</term>
<term>Genes, Dominant</term>
<term>Models, Genetic</term>
<term>Molecular Sequence Data</term>
<term>Polyribosomes (metabolism)</term>
<term>Protein Biosynthesis</term>
<term>Protein Synthesis Inhibitors (metabolism)</term>
<term>RNA Helicases (metabolism)</term>
<term>RNA, Messenger (metabolism)</term>
<term>RNA, Ribosomal (genetics)</term>
<term>RNA, Ribosomal (metabolism)</term>
<term>RNA-Binding Proteins</term>
<term>Saccharomyces cerevisiae (metabolism)</term>
<term>Saccharomyces cerevisiae Proteins</term>
<term>Sequence Homology, Amino Acid</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>ARN messager (métabolisme)</term>
<term>ARN ribosomique (génétique)</term>
<term>ARN ribosomique (métabolisme)</term>
<term>Biosynthèse des protéines</term>
<term>Clonage moléculaire</term>
<term>Division cellulaire (génétique)</term>
<term>Données de séquences moléculaires</term>
<term>Facteurs temps</term>
<term>Galactose (pharmacologie)</term>
<term>Gènes dominants</term>
<term>Inhibiteurs de la synthèse protéique (métabolisme)</term>
<term>Modèles génétiques</term>
<term>Polyribosomes (métabolisme)</term>
<term>Protéines de Saccharomyces cerevisiae</term>
<term>Protéines de liaison à l'ARN</term>
<term>Protéines fongiques (génétique)</term>
<term>Protéines fongiques (métabolisme)</term>
<term>Protéines fongiques (physiologie)</term>
<term>RNA helicases (métabolisme)</term>
<term>Régulation de l'expression des gènes fongiques</term>
<term>Saccharomyces cerevisiae (métabolisme)</term>
<term>Similitude de séquences d'acides aminés</term>
<term>Séquence d'acides aminés</term>
<term>Technique de Northern</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Fungal Proteins</term>
<term>RNA, Ribosomal</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Cell Division</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ARN ribosomique</term>
<term>Division cellulaire</term>
<term>Protéines fongiques</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Fungal Proteins</term>
<term>Polyribosomes</term>
<term>Protein Synthesis Inhibitors</term>
<term>RNA Helicases</term>
<term>RNA, Messenger</term>
<term>RNA, Ribosomal</term>
<term>Saccharomyces cerevisiae</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>ARN messager</term>
<term>ARN ribosomique</term>
<term>Inhibiteurs de la synthèse protéique</term>
<term>Polyribosomes</term>
<term>Protéines fongiques</term>
<term>RNA helicases</term>
<term>Saccharomyces cerevisiae</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Galactose</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Galactose</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Protéines fongiques</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Fungal Proteins</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term>
<term>Blotting, Northern</term>
<term>Cloning, Molecular</term>
<term>Gene Expression Regulation, Fungal</term>
<term>Genes, Dominant</term>
<term>Models, Genetic</term>
<term>Molecular Sequence Data</term>
<term>Protein Biosynthesis</term>
<term>RNA-Binding Proteins</term>
<term>Saccharomyces cerevisiae Proteins</term>
<term>Sequence Homology, Amino Acid</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Biosynthèse des protéines</term>
<term>Clonage moléculaire</term>
<term>Données de séquences moléculaires</term>
<term>Facteurs temps</term>
<term>Gènes dominants</term>
<term>Modèles génétiques</term>
<term>Protéines de Saccharomyces cerevisiae</term>
<term>Protéines de liaison à l'ARN</term>
<term>Régulation de l'expression des gènes fongiques</term>
<term>Similitude de séquences d'acides aminés</term>
<term>Séquence d'acides aminés</term>
<term>Technique de Northern</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The yeast NMD3 gene was identified in a two-hybrid screen using the nonsense-mediated mRNA decay factor, Upf1p, as bait. NMD3 was shown to encode an essential, highly conserved protein that associated principally with free 60S ribosomal subunits. Overexpression of a truncated form of Nmd3p, lacking 100 C-terminal amino acids and most of its Upf1p-interacting domain, had dominant-negative effects on both cell growth and protein synthesis and promoted the formation of polyribosome half-mers. These effects were eliminated by truncation of an additional 100 amino acids from Nmd3p. Overexpression of the nmd3delta100 allele also led to increased synthesis and destabilization of some ribosomal protein mRNAs, and increased synthesis and altered processing of 35S pre-rRNA. Our data suggest that Nmd3p has a role in the formation, function, or maintenance of the 60S ribosomal subunit and may provide a link for Upf1p to 80S monosomes.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">10445880</PMID>
<DateCompleted><Year>1999</Year>
<Month>08</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>06</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">1355-8382</ISSN>
<JournalIssue CitedMedium="Print"><Volume>5</Volume>
<Issue>8</Issue>
<PubDate><Year>1999</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>RNA (New York, N.Y.)</Title>
<ISOAbbreviation>RNA</ISOAbbreviation>
</Journal>
<ArticleTitle>Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.</ArticleTitle>
<Pagination><MedlinePgn>1055-70</MedlinePgn>
</Pagination>
<Abstract><AbstractText>The yeast NMD3 gene was identified in a two-hybrid screen using the nonsense-mediated mRNA decay factor, Upf1p, as bait. NMD3 was shown to encode an essential, highly conserved protein that associated principally with free 60S ribosomal subunits. Overexpression of a truncated form of Nmd3p, lacking 100 C-terminal amino acids and most of its Upf1p-interacting domain, had dominant-negative effects on both cell growth and protein synthesis and promoted the formation of polyribosome half-mers. These effects were eliminated by truncation of an additional 100 amino acids from Nmd3p. Overexpression of the nmd3delta100 allele also led to increased synthesis and destabilization of some ribosomal protein mRNAs, and increased synthesis and altered processing of 35S pre-rRNA. Our data suggest that Nmd3p has a role in the formation, function, or maintenance of the 60S ribosomal subunit and may provide a link for Upf1p to 80S monosomes.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Belk</LastName>
<ForeName>J P</ForeName>
<Initials>JP</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655-0122, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>He</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Jacobson</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>R01 GM027757</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>GM27757</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
<PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>RNA</MedlineTA>
<NlmUniqueID>9509184</NlmUniqueID>
<ISSNLinking>1355-8382</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D005656">Fungal Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C117894">NMD3 protein, S cerevisiae</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D011500">Protein Synthesis Inhibitors</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012333">RNA, Messenger</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012335">RNA, Ribosomal</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D016601">RNA-Binding Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D029701">Saccharomyces cerevisiae Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.6.1.-</RegistryNumber>
<NameOfSubstance UI="C074151">NAM7 protein, S cerevisiae</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.6.4.13</RegistryNumber>
<NameOfSubstance UI="D020365">RNA Helicases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>X2RN3Q8DNE</RegistryNumber>
<NameOfSubstance UI="D005690">Galactose</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000595" MajorTopicYN="N">Amino Acid Sequence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015152" MajorTopicYN="N">Blotting, Northern</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002455" MajorTopicYN="N">Cell Division</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003001" MajorTopicYN="N">Cloning, Molecular</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005656" MajorTopicYN="N">Fungal Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005690" MajorTopicYN="N">Galactose</DescriptorName>
<QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015966" MajorTopicYN="N">Gene Expression Regulation, Fungal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005799" MajorTopicYN="N">Genes, Dominant</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008957" MajorTopicYN="N">Models, Genetic</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011132" MajorTopicYN="N">Polyribosomes</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014176" MajorTopicYN="N">Protein Biosynthesis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011500" MajorTopicYN="N">Protein Synthesis Inhibitors</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020365" MajorTopicYN="N">RNA Helicases</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012333" MajorTopicYN="N">RNA, Messenger</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012335" MajorTopicYN="N">RNA, Ribosomal</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016601" MajorTopicYN="Y">RNA-Binding Proteins</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012441" MajorTopicYN="N">Saccharomyces cerevisiae</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D029701" MajorTopicYN="Y">Saccharomyces cerevisiae Proteins</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017386" MajorTopicYN="N">Sequence Homology, Amino Acid</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1999</Year>
<Month>8</Month>
<Day>13</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1999</Year>
<Month>8</Month>
<Day>13</Day>
<Hour>0</Hour>
<Minute>1</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>1999</Year>
<Month>8</Month>
<Day>13</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">10445880</ArticleId>
<ArticleId IdType="pmc">PMC1369829</ArticleId>
<ArticleId IdType="doi">10.1017/s1355838299990027</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Mol Cell Biol. 1995 Apr;15(4):2145-56</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7891709</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1995 May;15(5):2772-81</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7739558</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 1995 May;6(5):611-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7545033</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10354-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7479783</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>RNA. 1995 Aug;1(6):610-23</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7489520</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>RNA. 1996 Feb;2(2):153-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8601282</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1996 Aug 15;382(6592):642-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8757137</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Biochem. 1996;65:693-739</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8811193</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1996 Oct;16(10):5491-506</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8816462</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1996 Oct 15;15(20):5701-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8896463</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1997 Mar;17(3):1580-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9032286</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1997 May 16;272(20):13372-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9148960</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nucleic Acids Res. 1997 Sep 1;25(17):3389-402</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9254694</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1997 Aug 29;272(35):22163-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9268361</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1997 Sep;17(9):5136-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9271391</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nucleic Acids Res. 1997 Dec 15;25(24):4872-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9396790</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nucleic Acids Res. 1998 Feb 15;26(4):1063-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9461469</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1998 Mar 2;17(5):1487-96</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9482745</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nucleic Acids Res. 1998 May 15;26(10):2442-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9580698</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1998 May 15;17(10):2914-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9582285</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1998 Jun 1;12(11):1665-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9620853</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10009-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9707591</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nucleic Acids Res. 1999 Jan 1;27(1):69-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9847145</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1999 Mar;19(3):2389-99</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10022925</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods. 1999 Jan;17(1):28-37</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10075880</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1995 Feb 15;9(4):437-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7883168</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochemistry. 1977 May 31;16(11):2343-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">558799</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">271968</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Anal Biochem. 1983 Jul 1;132(1):6-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6312838</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1985 Jan;5(1):99-108</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3885011</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1986 May;6(5):1535-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3537704</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1987 Aug 25;262(24):11501-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3624224</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1981 Jan;1(1):51-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6765595</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Gene. 1987;60(2-3):237-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3327750</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1988 Feb;2(2):160-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3282992</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1988 May;8(5):2005-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2838740</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 1989 Feb 24;56(4):619-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2645056</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1989 Jul 20;340(6230):245-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2547163</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Genet. 1989 Jun;5(6):185-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2672459</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Genet. 1989 Dec;16(5-6):339-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2692852</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods Enzymol. 1989;180:347-69</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2482424</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1990 May;10(5):2269-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2183028</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods Enzymol. 1991;194:281-301</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2005793</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1991 May;11(5):2723-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2017175</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1991 Nov;11(11):5681-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1922070</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Gen Genet. 1991 Nov;230(1-2):129-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1745225</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1991 Dec;5(12A):2303-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1748286</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1992 May;12(5):2165-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1569946</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1993 Aug;13(8):4826-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8336719</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1993 Aug;7(8):1632-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8393418</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7034-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8346213</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1993 Sep;7(9):1737-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8370523</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1994 Aug 18;370(6490):578-81</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8052314</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1994 Apr 1;8(7):855-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7926773</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Biochem Sci. 1994 Aug;19(8):336-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7940679</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1995 Feb 15;9(4):423-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7883167</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>États-Unis</li>
</country>
</list>
<tree><noCountry><name sortKey="He, F" sort="He, F" uniqKey="He F" first="F" last="He">F. He</name>
<name sortKey="Jacobson, A" sort="Jacobson, A" uniqKey="Jacobson A" first="A" last="Jacobson">A. Jacobson</name>
</noCountry>
<country name="États-Unis"><noRegion><name sortKey="Belk, J P" sort="Belk, J P" uniqKey="Belk J" first="J P" last="Belk">J P Belk</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002477 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 002477 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:10445880
   |texte=   Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:10445880" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a MersV1

This area was generated with Dilib version V0.6.33.
Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021

	Serveur d'exploration MERS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration MERS

Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.

Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki