MersV1, PubMed, Checkpoint, bibRecord, 002171

The discovery, positioning and verification of a set of transcription-associated motifs in vertebrates.

Identifieur interne : 002171 ( PubMed/Checkpoint ); précédent : 002170; suivant : 002172

The discovery, positioning and verification of a set of transcription-associated motifs in vertebrates.

Auteurs : Laurence Ettwiller [Royaume-Uni] ; Benedict Paten ; Marcel Souren ; Felix Loosli ; Jochen Wittbrodt ; Ewan Birney

Source :

Genome biology [ 1474-760X ] ; 2005.

RBID : pubmed:16356267

Descripteurs français

English descriptors

KwdEn :
- Animals, Conserved Sequence, Embryo, Nonmammalian (cytology), Evolution, Molecular, Humans, Promoter Regions, Genetic (genetics), Regulatory Sequences, Nucleic Acid (genetics), Reproducibility of Results, SELEX Aptamer Technique, Sequence Deletion (genetics), Takifugu (genetics), Transcription, Genetic (genetics), Transgenes, Vertebrates (genetics).
MESH :
- cytology : Embryo, Nonmammalian.
- genetics : Promoter Regions, Genetic, Regulatory Sequences, Nucleic Acid, Sequence Deletion, Takifugu, Transcription, Genetic, Vertebrates.
- Animals, Conserved Sequence, Evolution, Molecular, Humans, Reproducibility of Results, SELEX Aptamer Technique, Transgenes.

Abstract

We have developed several new methods to investigate transcriptional motifs in vertebrates. We developed a specific alignment tool appropriate for regions involved in transcription control, and exhaustively enumerated all possible 12-mers for involvement in transcription by virtue of their mammalian conservation. We then used deeper comparative analysis across vertebrates to identify the active instances of these motifs. We have shown experimentally in Medaka fish that a subset of these predictions is involved in transcription.

DOI: 10.1186/gb-2005-6-12-r104
PubMed: 16356267

Affiliations:

Royaume-Uni

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 002293
to stream PubMed, to step Curation: 002293

Links to Exploration step

pubmed:16356267

Le document en format XML

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<front><div type="abstract" xml:lang="en">We have developed several new methods to investigate transcriptional motifs in vertebrates. We developed a specific alignment tool appropriate for regions involved in transcription control, and exhaustively enumerated all possible 12-mers for involvement in transcription by virtue of their mammalian conservation. We then used deeper comparative analysis across vertebrates to identify the active instances of these motifs. We have shown experimentally in Medaka fish that a subset of these predictions is involved in transcription.</div>
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<name sortKey="Paten, Benedict" sort="Paten, Benedict" uniqKey="Paten B" first="Benedict" last="Paten">Benedict Paten</name>
<name sortKey="Souren, Marcel" sort="Souren, Marcel" uniqKey="Souren M" first="Marcel" last="Souren">Marcel Souren</name>
<name sortKey="Wittbrodt, Jochen" sort="Wittbrodt, Jochen" uniqKey="Wittbrodt J" first="Jochen" last="Wittbrodt">Jochen Wittbrodt</name>
</noCountry>
<country name="Royaume-Uni"><noRegion><name sortKey="Ettwiller, Laurence" sort="Ettwiller, Laurence" uniqKey="Ettwiller L" first="Laurence" last="Ettwiller">Laurence Ettwiller</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002171 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 002171 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:16356267
   |texte=   The discovery, positioning and verification of a set of transcription-associated motifs in vertebrates.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:16356267" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a MersV1

This area was generated with Dilib version V0.6.33.
Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021

	Serveur d'exploration MERS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration MERS

The discovery, positioning and verification of a set of transcription-associated motifs in vertebrates.

The discovery, positioning and verification of a set of transcription-associated motifs in vertebrates.

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English descriptors

Abstract

Links toward previous steps (curation, corpus...)

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Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki