Interactions of bovine serum albumin with aluminum polyoxocations and aluminum hydroxide.
Identifieur interne : 002119 ( PubMed/Checkpoint ); précédent : 002118; suivant : 002120Interactions of bovine serum albumin with aluminum polyoxocations and aluminum hydroxide.
Auteurs : Olivier Deschaume ; Kirill L. Shafran ; Carole C. PerrySource :
- Langmuir : the ACS journal of surfaces and colloids [ 0743-7463 ] ; 2006.
Descripteurs français
- KwdFr :
- Aluminium (), Animaux, Bovins, Cations (), Concentration en ions d'hydrogène, Conformation moléculaire, Diffraction des rayons X, Diffusion de rayonnements, Hydroxyde d'aluminium (), Hydroxydes (), Nanoparticules (), Relation dose-effet des médicaments, Spectroscopie par résonance magnétique, Sérumalbumine bovine (), Température.
- MESH :
- Aluminium, Animaux, Bovins, Cations, Concentration en ions d'hydrogène, Conformation moléculaire, Diffraction des rayons X, Diffusion de rayonnements, Hydroxyde d'aluminium, Hydroxydes, Nanoparticules, Relation dose-effet des médicaments, Spectroscopie par résonance magnétique, Sérumalbumine bovine, Température.
English descriptors
- KwdEn :
- Aluminum (chemistry), Aluminum Hydroxide (chemistry), Animals, Cations (chemistry), Cattle, Dose-Response Relationship, Drug, Hydrogen-Ion Concentration, Hydroxides (chemistry), Magnetic Resonance Spectroscopy, Molecular Conformation, Nanoparticles (chemistry), Scattering, Radiation, Serum Albumin, Bovine (chemistry), Temperature, X-Ray Diffraction.
- MESH :
- chemical , chemistry : Aluminum, Aluminum Hydroxide, Cations, Hydroxides, Serum Albumin, Bovine.
- chemistry : Nanoparticles.
- Animals, Cattle, Dose-Response Relationship, Drug, Hydrogen-Ion Concentration, Magnetic Resonance Spectroscopy, Molecular Conformation, Scattering, Radiation, Temperature, X-Ray Diffraction.
Abstract
Interactions of aqueous solutions of aluminum polyoxocations (Al13-mers and Al30-mers) and aluminum hydroxide suspensions of varying particle sizes (26, 55, and 82 nm) with a model protein, bovine serum albumin (BSA), have been investigated using potentiometry, conductometry, viscometry, 27Al solution NMR, UV-vis spectroscopy, dynamic light scattering, zeta-potential measurements, thermogravimetry, X-ray diffraction, and scanning electron microscopy. Increasing amounts of BSA partially convert Al13-mers and, to a larger extent, Al30-mers into amorphous Al hydroxide without gel formation. At the same time, BSA molecules can form unstable aggregates in the Al polyoxocation solutions which redisperse easily upon standing. In the case of Al hydroxide sols, BSA addition causes substantial gelation, the extent of which is proportional to the amount of BSA added and inversely related to the Al hydroxide particle size. Upon freeze-drying or centrifugation of Al species-BSA solutions, an interesting sheetlike morphology with 150-200 nm wide nanoribbons is observed for pure Al hydroxide nanoparticles and for solutions of Al polyoxocations with the highest amount of BSA studied. On the basis of the combined solution, colloidal and solid-state characterization of model Al species-BSA systems, a qualitative model of possible interactions in the Al polyoxocation-BSA and Al hydroxide-BSA systems is proposed wherein core-shell hybrid nanoparticles are formed from protein "core" and Al polyoxocation "shell" or Al hydroxide "core" and protein "shell".
DOI: 10.1021/la061285h
PubMed: 17107003
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:17107003Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Interactions of bovine serum albumin with aluminum polyoxocations and aluminum hydroxide.</title><author><name sortKey="Deschaume, Olivier" sort="Deschaume, Olivier" uniqKey="Deschaume O" first="Olivier" last="Deschaume">Olivier Deschaume</name><affiliation><nlm:affiliation>School of Biomedical and Natural Sciences, Nottingham Trent University, Clifton Lane, Clifton, Nottingham, The United Kingdom.</nlm:affiliation><wicri:noCountry code="subField">The United Kingdom</wicri:noCountry></affiliation></author><author><name sortKey="Shafran, Kirill L" sort="Shafran, Kirill L" uniqKey="Shafran K" first="Kirill L" last="Shafran">Kirill L. Shafran</name></author><author><name sortKey="Perry, Carole C" sort="Perry, Carole C" uniqKey="Perry C" first="Carole C" last="Perry">Carole C. Perry</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="RBID">pubmed:17107003</idno><idno type="pmid">17107003</idno><idno type="doi">10.1021/la061285h</idno><idno type="wicri:Area/PubMed/Corpus">002215</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002215</idno><idno type="wicri:Area/PubMed/Curation">002215</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002215</idno><idno type="wicri:Area/PubMed/Checkpoint">002119</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002119</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Interactions of bovine serum albumin with aluminum polyoxocations and aluminum hydroxide.</title><author><name sortKey="Deschaume, Olivier" sort="Deschaume, Olivier" uniqKey="Deschaume O" first="Olivier" last="Deschaume">Olivier Deschaume</name><affiliation><nlm:affiliation>School of Biomedical and Natural Sciences, Nottingham Trent University, Clifton Lane, Clifton, Nottingham, The United Kingdom.</nlm:affiliation><wicri:noCountry code="subField">The United Kingdom</wicri:noCountry></affiliation></author><author><name sortKey="Shafran, Kirill L" sort="Shafran, Kirill L" uniqKey="Shafran K" first="Kirill L" last="Shafran">Kirill L. Shafran</name></author><author><name sortKey="Perry, Carole C" sort="Perry, Carole C" uniqKey="Perry C" first="Carole C" last="Perry">Carole C. Perry</name></author></analytic><series><title level="j">Langmuir : the ACS journal of surfaces and colloids</title><idno type="ISSN">0743-7463</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aluminum (chemistry)</term><term>Aluminum Hydroxide (chemistry)</term><term>Animals</term><term>Cations (chemistry)</term><term>Cattle</term><term>Dose-Response Relationship, Drug</term><term>Hydrogen-Ion Concentration</term><term>Hydroxides (chemistry)</term><term>Magnetic Resonance Spectroscopy</term><term>Molecular Conformation</term><term>Nanoparticles (chemistry)</term><term>Scattering, Radiation</term><term>Serum Albumin, Bovine (chemistry)</term><term>Temperature</term><term>X-Ray Diffraction</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Aluminium ()</term><term>Animaux</term><term>Bovins</term><term>Cations ()</term><term>Concentration en ions d'hydrogène</term><term>Conformation moléculaire</term><term>Diffraction des rayons X</term><term>Diffusion de rayonnements</term><term>Hydroxyde d'aluminium ()</term><term>Hydroxydes ()</term><term>Nanoparticules ()</term><term>Relation dose-effet des médicaments</term><term>Spectroscopie par résonance magnétique</term><term>Sérumalbumine bovine ()</term><term>Température</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Aluminum</term><term>Aluminum Hydroxide</term><term>Cations</term><term>Hydroxides</term><term>Serum Albumin, Bovine</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nanoparticles</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cattle</term><term>Dose-Response Relationship, Drug</term><term>Hydrogen-Ion Concentration</term><term>Magnetic Resonance Spectroscopy</term><term>Molecular Conformation</term><term>Scattering, Radiation</term><term>Temperature</term><term>X-Ray Diffraction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Aluminium</term><term>Animaux</term><term>Bovins</term><term>Cations</term><term>Concentration en ions d'hydrogène</term><term>Conformation moléculaire</term><term>Diffraction des rayons X</term><term>Diffusion de rayonnements</term><term>Hydroxyde d'aluminium</term><term>Hydroxydes</term><term>Nanoparticules</term><term>Relation dose-effet des médicaments</term><term>Spectroscopie par résonance magnétique</term><term>Sérumalbumine bovine</term><term>Température</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Interactions of aqueous solutions of aluminum polyoxocations (Al13-mers and Al30-mers) and aluminum hydroxide suspensions of varying particle sizes (26, 55, and 82 nm) with a model protein, bovine serum albumin (BSA), have been investigated using potentiometry, conductometry, viscometry, 27Al solution NMR, UV-vis spectroscopy, dynamic light scattering, zeta-potential measurements, thermogravimetry, X-ray diffraction, and scanning electron microscopy. Increasing amounts of BSA partially convert Al13-mers and, to a larger extent, Al30-mers into amorphous Al hydroxide without gel formation. At the same time, BSA molecules can form unstable aggregates in the Al polyoxocation solutions which redisperse easily upon standing. In the case of Al hydroxide sols, BSA addition causes substantial gelation, the extent of which is proportional to the amount of BSA added and inversely related to the Al hydroxide particle size. Upon freeze-drying or centrifugation of Al species-BSA solutions, an interesting sheetlike morphology with 150-200 nm wide nanoribbons is observed for pure Al hydroxide nanoparticles and for solutions of Al polyoxocations with the highest amount of BSA studied. On the basis of the combined solution, colloidal and solid-state characterization of model Al species-BSA systems, a qualitative model of possible interactions in the Al polyoxocation-BSA and Al hydroxide-BSA systems is proposed wherein core-shell hybrid nanoparticles are formed from protein "core" and Al polyoxocation "shell" or Al hydroxide "core" and protein "shell".</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">17107003</PMID><DateCompleted><Year>2007</Year><Month>03</Month><Day>13</Day></DateCompleted><DateRevised><Year>2017</Year><Month>11</Month><Day>16</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0743-7463</ISSN><JournalIssue CitedMedium="Print"><Volume>22</Volume><Issue>24</Issue><PubDate><Year>2006</Year><Month>Nov</Month><Day>21</Day></PubDate></JournalIssue><Title>Langmuir : the ACS journal of surfaces and colloids</Title><ISOAbbreviation>Langmuir</ISOAbbreviation></Journal><ArticleTitle>Interactions of bovine serum albumin with aluminum polyoxocations and aluminum hydroxide.</ArticleTitle><Pagination><MedlinePgn>10078-88</MedlinePgn></Pagination><Abstract><AbstractText>Interactions of aqueous solutions of aluminum polyoxocations (Al13-mers and Al30-mers) and aluminum hydroxide suspensions of varying particle sizes (26, 55, and 82 nm) with a model protein, bovine serum albumin (BSA), have been investigated using potentiometry, conductometry, viscometry, 27Al solution NMR, UV-vis spectroscopy, dynamic light scattering, zeta-potential measurements, thermogravimetry, X-ray diffraction, and scanning electron microscopy. Increasing amounts of BSA partially convert Al13-mers and, to a larger extent, Al30-mers into amorphous Al hydroxide without gel formation. At the same time, BSA molecules can form unstable aggregates in the Al polyoxocation solutions which redisperse easily upon standing. In the case of Al hydroxide sols, BSA addition causes substantial gelation, the extent of which is proportional to the amount of BSA added and inversely related to the Al hydroxide particle size. Upon freeze-drying or centrifugation of Al species-BSA solutions, an interesting sheetlike morphology with 150-200 nm wide nanoribbons is observed for pure Al hydroxide nanoparticles and for solutions of Al polyoxocations with the highest amount of BSA studied. On the basis of the combined solution, colloidal and solid-state characterization of model Al species-BSA systems, a qualitative model of possible interactions in the Al polyoxocation-BSA and Al hydroxide-BSA systems is proposed wherein core-shell hybrid nanoparticles are formed from protein "core" and Al polyoxocation "shell" or Al hydroxide "core" and protein "shell".</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Deschaume</LastName><ForeName>Olivier</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>School of Biomedical and Natural Sciences, Nottingham Trent University, Clifton Lane, Clifton, Nottingham, The United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shafran</LastName><ForeName>Kirill L</ForeName><Initials>KL</Initials></Author><Author ValidYN="Y"><LastName>Perry</LastName><ForeName>Carole C</ForeName><Initials>CC</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Langmuir</MedlineTA><NlmUniqueID>9882736</NlmUniqueID><ISSNLinking>0743-7463</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002412">Cations</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006878">Hydroxides</NameOfSubstance></Chemical><Chemical><RegistryNumber>27432CM55Q</RegistryNumber><NameOfSubstance UI="D012710">Serum Albumin, Bovine</NameOfSubstance></Chemical><Chemical><RegistryNumber>5QB0T2IUN0</RegistryNumber><NameOfSubstance UI="D000536">Aluminum Hydroxide</NameOfSubstance></Chemical><Chemical><RegistryNumber>CPD4NFA903</RegistryNumber><NameOfSubstance UI="D000535">Aluminum</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000535" MajorTopicYN="N">Aluminum</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000536" MajorTopicYN="N">Aluminum Hydroxide</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002412" MajorTopicYN="N">Cations</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002417" MajorTopicYN="N">Cattle</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004305" MajorTopicYN="N">Dose-Response Relationship, Drug</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006863" MajorTopicYN="N">Hydrogen-Ion Concentration</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006878" MajorTopicYN="N">Hydroxides</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009682" MajorTopicYN="N">Magnetic Resonance Spectroscopy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008968" MajorTopicYN="N">Molecular Conformation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053758" MajorTopicYN="N">Nanoparticles</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012542" MajorTopicYN="N">Scattering, Radiation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012710" MajorTopicYN="N">Serum Albumin, Bovine</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013696" MajorTopicYN="N">Temperature</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014961" MajorTopicYN="N">X-Ray Diffraction</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2006</Year><Month>11</Month><Day>17</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>3</Month><Day>14</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2006</Year><Month>11</Month><Day>17</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">17107003</ArticleId><ArticleId IdType="doi">10.1021/la061285h</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Deschaume, Olivier" sort="Deschaume, Olivier" uniqKey="Deschaume O" first="Olivier" last="Deschaume">Olivier Deschaume</name><name sortKey="Perry, Carole C" sort="Perry, Carole C" uniqKey="Perry C" first="Carole C" last="Perry">Carole C. Perry</name><name sortKey="Shafran, Kirill L" sort="Shafran, Kirill L" uniqKey="Shafran K" first="Kirill L" last="Shafran">Kirill L. Shafran</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002119 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 002119 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:17107003
|texte= Interactions of bovine serum albumin with aluminum polyoxocations and aluminum hydroxide.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:17107003" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |