A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case.
Identifieur interne : 001C16 ( PubMed/Checkpoint ); précédent : 001C15; suivant : 001C17A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case.
Auteurs : Ali S. Omrani [Arabie saoudite] ; Mohammad Abdul Matin ; Qais Haddad ; Daifullah Al-Nakhli ; Ziad A. Memish ; Ali M. AlbarrakSource :
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [ 1878-3511 ] ; 2013.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Coronavirus (), Coronavirus (génétique), Coronavirus (isolement et purification), Humains, Infections de l'appareil respiratoire (diagnostic), Infections de l'appareil respiratoire (transmission), Infections de l'appareil respiratoire (épidémiologie), Infections à coronavirus (diagnostic), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Issue fatale, Maladies transmissibles émergentes (diagnostic), Maladies transmissibles émergentes (épidémiologie), Moyen Orient, Mâle, Poumon (anatomopathologie), Poumon (imagerie diagnostique), Surveillance sentinelle, Syndrome, Tomodensitométrie.
- MESH :
- anatomopathologie : Poumon.
- diagnostic : Infections de l'appareil respiratoire, Infections à coronavirus, Maladies transmissibles émergentes.
- génétique : Coronavirus.
- imagerie diagnostique : Poumon.
- isolement et purification : Coronavirus.
- épidémiologie : Infections de l'appareil respiratoire, Infections à coronavirus, Maladies transmissibles émergentes.
- Adulte, Adulte d'âge moyen, Coronavirus, Humains, Issue fatale, Moyen Orient, Mâle, Surveillance sentinelle, Syndrome, Tomodensitométrie.
English descriptors
- KwdEn :
- Adult, Communicable Diseases, Emerging (diagnosis), Communicable Diseases, Emerging (epidemiology), Coronavirus (classification), Coronavirus (genetics), Coronavirus (isolation & purification), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Fatal Outcome, Humans, Lung (diagnostic imaging), Lung (pathology), Male, Middle Aged, Middle East, Respiratory Tract Infections (diagnosis), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (transmission), Sentinel Surveillance, Syndrome, Tomography, X-Ray Computed.
- MESH :
- classification : Coronavirus.
- diagnosis : Communicable Diseases, Emerging, Coronavirus Infections, Respiratory Tract Infections.
- diagnostic imaging : Lung.
- epidemiology : Communicable Diseases, Emerging, Coronavirus Infections, Respiratory Tract Infections.
- genetics : Coronavirus.
- isolation & purification : Coronavirus.
- pathology : Lung.
- transmission : Coronavirus Infections, Respiratory Tract Infections.
- Adult, Fatal Outcome, Humans, Male, Middle Aged, Middle East, Sentinel Surveillance, Syndrome, Tomography, X-Ray Computed.
Abstract
Ninety confirmed cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been reported to the World Health Organization. We report the details of a second family cluster of MERS-CoV infections from Riyadh, Saudi Arabia.
DOI: 10.1016/j.ijid.2013.07.001
PubMed: 23916548
Affiliations:
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pubmed:23916548Le document en format XML
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<front><div type="abstract" xml:lang="en">Ninety confirmed cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been reported to the World Health Organization. We report the details of a second family cluster of MERS-CoV infections from Riyadh, Saudi Arabia.</div>
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<Title>International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases</Title>
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<ArticleTitle>A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Ninety confirmed cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been reported to the World Health Organization. We report the details of a second family cluster of MERS-CoV infections from Riyadh, Saudi Arabia.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We present the clinical, laboratory and epidemiological details of 3 patients from a family cluster of MERS-CoV infections.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The first patient developed respiratory symptoms and fever 14 days after admission to hospital for an unrelated reason. He died 11 days later with multi-organ failure. Two of his brothers presented later to another hospital with respiratory symptoms and fever. MERS-CoV infection in the latter 2 patients was confirmed by reverse transcriptase polymerase chain reaction testing. All 3 patients had fever, cough, shortness of breath, bilateral infiltrates on chest x-ray, thrombocytopenia, lymphopenia and rises in serum creatinine kinase and alanine transaminase. No hospital or other social contacts are known to have acquired the infection. It appears that the index patient in this cluster acquired MERS-CoV infection whilst in hospital from an unrecognized mild or asymptomatic case.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">MERS-CoV acquisition from unrecognized mild or asymptomatic cases may be a more important contributor to ongoing transmission than previously appreciated.</AbstractText>
<CopyrightInformation>Copyright © 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.</CopyrightInformation>
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<ForeName>Ali S</ForeName>
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<tree><noCountry><name sortKey="Al Nakhli, Daifullah" sort="Al Nakhli, Daifullah" uniqKey="Al Nakhli D" first="Daifullah" last="Al-Nakhli">Daifullah Al-Nakhli</name>
<name sortKey="Albarrak, Ali M" sort="Albarrak, Ali M" uniqKey="Albarrak A" first="Ali M" last="Albarrak">Ali M. Albarrak</name>
<name sortKey="Haddad, Qais" sort="Haddad, Qais" uniqKey="Haddad Q" first="Qais" last="Haddad">Qais Haddad</name>
<name sortKey="Matin, Mohammad Abdul" sort="Matin, Mohammad Abdul" uniqKey="Matin M" first="Mohammad Abdul" last="Matin">Mohammad Abdul Matin</name>
<name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A" last="Memish">Ziad A. Memish</name>
</noCountry>
<country name="Arabie saoudite"><noRegion><name sortKey="Omrani, Ali S" sort="Omrani, Ali S" uniqKey="Omrani A" first="Ali S" last="Omrani">Ali S. Omrani</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
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