Severe acute respiratory syndrome vs. the Middle East respiratory syndrome.
Identifieur interne : 001742 ( PubMed/Checkpoint ); précédent : 001741; suivant : 001743Severe acute respiratory syndrome vs. the Middle East respiratory syndrome.
Auteurs : David S. Hui [Royaume-Uni] ; Ziad A. Memish ; Alimuddin ZumlaSource :
- Current opinion in pulmonary medicine [ 1531-6971 ] ; 2014.
Descripteurs français
- KwdFr :
- Acide mycophénolique (usage thérapeutique), Animaux, Antiviraux (usage thérapeutique), Chameaux, Charge virale, Chiroptera, Coronavirus (immunologie), Coronavirus (isolement et purification), Coronavirus (pathogénicité), Diagnostic différentiel, Femelle, Humains, Immunité innée, Infection croisée (), Infection croisée (diagnostic), Infections à coronavirus (), Infections à coronavirus (diagnostic), Interférons (usage thérapeutique), Moyen Orient, Mâle, Poumon (imagerie diagnostique), Poumon (virologie), Période d'incubation de maladie infectieuse, Radiographie, Ribavirine (usage thérapeutique), Réaction de polymérisation en chaine en temps réel, Répartition par sexe, Répartition par âge, Santé publique, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (épidémiologie), Évolution de la maladie.
- MESH :
- diagnostic : Infection croisée, Infections à coronavirus, Syndrome respiratoire aigu sévère.
- imagerie diagnostique : Poumon.
- immunologie : Coronavirus.
- isolement et purification : Coronavirus.
- pathogénicité : Coronavirus.
- usage thérapeutique : Acide mycophénolique, Antiviraux, Interférons, Ribavirine.
- virologie : Poumon.
- épidémiologie : Syndrome respiratoire aigu sévère.
- Animaux, Chameaux, Charge virale, Chiroptera, Diagnostic différentiel, Femelle, Humains, Immunité innée, Infection croisée, Infections à coronavirus, Moyen Orient, Mâle, Période d'incubation de maladie infectieuse, Radiographie, Réaction de polymérisation en chaine en temps réel, Répartition par sexe, Répartition par âge, Santé publique, Syndrome respiratoire aigu sévère, Évolution de la maladie.
English descriptors
- KwdEn :
- Age Distribution, Animals, Antiviral Agents (therapeutic use), Camelus, Chiroptera, Coronavirus (immunology), Coronavirus (isolation & purification), Coronavirus (pathogenicity), Coronavirus Infections (diagnosis), Coronavirus Infections (therapy), Cross Infection (diagnosis), Cross Infection (therapy), Diagnosis, Differential, Disease Progression, Female, Humans, Immunity, Innate, Infectious Disease Incubation Period, Interferons (therapeutic use), Lung (diagnostic imaging), Lung (virology), Male, Middle East, Mycophenolic Acid (therapeutic use), Public Health, Radiography, Real-Time Polymerase Chain Reaction, Ribavirin (therapeutic use), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (therapy), Sex Distribution, Viral Load.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Interferons, Mycophenolic Acid, Ribavirin.
- diagnosis : Coronavirus Infections, Cross Infection, Severe Acute Respiratory Syndrome.
- diagnostic imaging : Lung.
- epidemiology : Severe Acute Respiratory Syndrome.
- immunology : Coronavirus.
- isolation & purification : Coronavirus.
- pathogenicity : Coronavirus.
- therapy : Coronavirus Infections, Cross Infection, Severe Acute Respiratory Syndrome.
- virology : Lung.
- Age Distribution, Animals, Camelus, Chiroptera, Diagnosis, Differential, Disease Progression, Female, Humans, Immunity, Innate, Infectious Disease Incubation Period, Male, Middle East, Public Health, Radiography, Real-Time Polymerase Chain Reaction, Sex Distribution, Viral Load.
Abstract
This review compares the clinical features, laboratory aspects and treatment options of severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS).
DOI: 10.1097/MCP.0000000000000046
PubMed: 24626235
Affiliations:
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innée</term><term>Infection croisée</term><term>Infections à coronavirus</term><term>Moyen Orient</term><term>Mâle</term><term>Période d'incubation de maladie infectieuse</term><term>Radiographie</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Répartition par sexe</term><term>Répartition par âge</term><term>Santé publique</term><term>Syndrome respiratoire aigu sévère</term><term>Évolution de la maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This review compares the clinical features, laboratory aspects and treatment options of severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24626235</PMID><DateCompleted><Year>2015</Year><Month>01</Month><Day>09</Day></DateCompleted><DateRevised><Year>2016</Year><Month>11</Month><Day>25</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-6971</ISSN><JournalIssue CitedMedium="Internet"><Volume>20</Volume><Issue>3</Issue><PubDate><Year>2014</Year><Month>May</Month></PubDate></JournalIssue><Title>Current opinion in pulmonary medicine</Title><ISOAbbreviation>Curr Opin Pulm Med</ISOAbbreviation></Journal><ArticleTitle>Severe acute respiratory syndrome vs. the Middle East respiratory syndrome.</ArticleTitle><Pagination><MedlinePgn>233-41</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/MCP.0000000000000046</ELocationID><Abstract><AbstractText Label="PURPOSE OF REVIEW" NlmCategory="OBJECTIVE">This review compares the clinical features, laboratory aspects and treatment options of severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS).</AbstractText><AbstractText Label="RECENT FINDINGS" NlmCategory="RESULTS">Bats are the natural reservoirs of SARS-like coronaviruses (CoVs) and are likely the reservoir of MERS coronavirus (MERS-CoV). Although a small number of camels have been found to have positive nasal swabs by real-time polymerase chain reaction and to carry antibody against MERS-CoV, the transmission route and the intermediary animal source remain uncertain amongst the sporadic primary cases. Both SARS-CoV and MERS-CoV may cause severe respiratory failure and extrapulmonary features such as diarrhoea, whereas mild or asymptomatic cases also occur in both conditions. In comparison with SARS, patients with MERS are older with male predominance, more comorbid illness and relatively lower human-to-human transmission potential. Although the viral kinetics of MERS-CoV remain unknown, nosocomial infections of MERS occur early within the first week of illness of the index case, whereas those of SARS occurred mainly in the second week of illness when the patient's upper airway viral load peaks on day 10 of illness. In-vitro data suggest that interferon (IFN) with or without ribavirin and mycophenolic acid may inhibit MERS-CoV, whereas protease inhibitors and IFN have inhibitory activity against SARS-CoV.</AbstractText><AbstractText Label="SUMMARY" NlmCategory="CONCLUSIONS">Although there are some similarities in the clinical features, MERS progresses to respiratory failure much more rapidly than SARS. The higher case fatality rate of MERS is likely related to older age and comorbid illness. More studies are needed to understand MERS-CoV in order to guide public health infection control measures and treatment.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hui</LastName><ForeName>David S</ForeName><Initials>DS</Initials><AffiliationInfo><Affiliation>aDepartment of Medicine & Therapeutics, Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong bMinistry of Health, Al-Faisal University, Riyadh, Kingdom of Saudi Arabia cDivision of Infection and Immunity, Department of Infection, Centre for Clinical Microbiology, University College London dNIHR Biomedical Research Centre, University College London Hospitals, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Memish</LastName><ForeName>Ziad A</ForeName><Initials>ZA</Initials></Author><Author ValidYN="Y"><LastName>Zumla</LastName><ForeName>Alimuddin</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Curr Opin Pulm Med</MedlineTA><NlmUniqueID>9503765</NlmUniqueID><ISSNLinking>1070-5287</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>49717AWG6K</RegistryNumber><NameOfSubstance UI="D012254">Ribavirin</NameOfSubstance></Chemical><Chemical><RegistryNumber>9008-11-1</RegistryNumber><NameOfSubstance UI="D007372">Interferons</NameOfSubstance></Chemical><Chemical><RegistryNumber>HU9DX48N0T</RegistryNumber><NameOfSubstance UI="D009173">Mycophenolic Acid</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D017677" MajorTopicYN="N">Age Distribution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002162" MajorTopicYN="N">Camelus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002685" MajorTopicYN="N">Chiroptera</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017934" MajorTopicYN="N">Coronavirus</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName><QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003428" MajorTopicYN="N">Cross Infection</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018450" MajorTopicYN="N">Disease Progression</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007113" MajorTopicYN="N">Immunity, Innate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055256" MajorTopicYN="N">Infectious Disease Incubation Period</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007372" MajorTopicYN="N">Interferons</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008877" MajorTopicYN="N">Middle East</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009173" MajorTopicYN="N">Mycophenolic Acid</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011634" MajorTopicYN="N">Public Health</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011859" MajorTopicYN="N">Radiography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D060888" MajorTopicYN="N">Real-Time Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012254" MajorTopicYN="N">Ribavirin</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017678" MajorTopicYN="N">Sex Distribution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019562" MajorTopicYN="N">Viral Load</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>3</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>3</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>1</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24626235</ArticleId><ArticleId IdType="doi">10.1097/MCP.0000000000000046</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><noCountry><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A" last="Memish">Ziad A. Memish</name><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name></noCountry><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Hui, David S" sort="Hui, David S" uniqKey="Hui D" first="David S" last="Hui">David S. Hui</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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