Estimating the risk of Middle East respiratory syndrome (MERS) death during the course of the outbreak in the Republic of Korea, 2015.
Identifieur interne : 001558 ( PubMed/Checkpoint ); précédent : 001557; suivant : 001559Estimating the risk of Middle East respiratory syndrome (MERS) death during the course of the outbreak in the Republic of Korea, 2015.
Auteurs : Kenji Mizumoto [Japon] ; Masaya Saitoh [Japon] ; Gerardo Chowell [États-Unis] ; Yuichiro Miyamatsu [Japon] ; Hiroshi Nishiura [Japon]Source :
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [ 1878-3511 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- mortalité : Infections à coronavirus.
- épidémiologie : Infections à coronavirus, République de Corée.
- Adulte d'âge moyen, Flambées de maladies, Humains, Risque.
English descriptors
- KwdEn :
- MESH :
- epidemiology : Coronavirus Infections, Republic of Korea.
- mortality : Coronavirus Infections.
- Disease Outbreaks, Humans, Middle Aged, Risk.
Abstract
A large cluster of the Middle East respiratory syndrome (MERS) linked to healthcare setting occurred from May to July 2015 in the Republic of Korea. The present study aimed to estimate the case fatality ratio (CFR) by appropriately taking into account the time delay from illness onset to death. We then compare our estimate against previously published values of the CFR for MERS, i.e., 20% and 40%.
DOI: 10.1016/j.ijid.2015.08.005
PubMed: 26275845
Affiliations:
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pubmed:26275845Le document en format XML
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<front><div type="abstract" xml:lang="en">A large cluster of the Middle East respiratory syndrome (MERS) linked to healthcare setting occurred from May to July 2015 in the Republic of Korea. The present study aimed to estimate the case fatality ratio (CFR) by appropriately taking into account the time delay from illness onset to death. We then compare our estimate against previously published values of the CFR for MERS, i.e., 20% and 40%.</div>
</front>
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<DateCompleted><Year>2016</Year>
<Month>09</Month>
<Day>16</Day>
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<Month>04</Month>
<Day>07</Day>
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<Title>International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases</Title>
<ISOAbbreviation>Int. J. Infect. Dis.</ISOAbbreviation>
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<ArticleTitle>Estimating the risk of Middle East respiratory syndrome (MERS) death during the course of the outbreak in the Republic of Korea, 2015.</ArticleTitle>
<Pagination><MedlinePgn>7-9</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ijid.2015.08.005</ELocationID>
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<Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">A large cluster of the Middle East respiratory syndrome (MERS) linked to healthcare setting occurred from May to July 2015 in the Republic of Korea. The present study aimed to estimate the case fatality ratio (CFR) by appropriately taking into account the time delay from illness onset to death. We then compare our estimate against previously published values of the CFR for MERS, i.e., 20% and 40%.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Dates of illness onset and death of the MERS outbreak in the Republic of Korea were extracted from secondary data sources. Using the known distribution of time from illness onset to death and an integral equation model, we estimated the delay-adjusted risk of MERS death for the South Korean cluster.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Our most up-to-date estimate of CFR for the MERS outbreak in South Korea was estimated at 20.0% (95% confidence intervals (CI): 14.6, 26.2). During the course of the outbreak, estimate of the CFR in real time appeared to have decreased and become significantly lower than 40%.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The risk of MERS death in Korea was consistent with published CFR. The estimate decreased with time perhaps due to time-dependent increase in case ascertainment. Crude ratio of cumulative deaths to cases underestimates the actual risk of MERS death because of time delay from illness onset to death.</AbstractText>
<CopyrightInformation>Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.</CopyrightInformation>
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<ForeName>Kenji</ForeName>
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<AffiliationInfo><Affiliation>Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 1538902, Japan.</Affiliation>
</AffiliationInfo>
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<ForeName>Masaya</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan; CREST, Japan Science and Technology Agency, Honcho 4-1-8, Kawaguchi, Saitama, 332-0012 Japan.</Affiliation>
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<Author ValidYN="Y"><LastName>Chowell</LastName>
<ForeName>Gerardo</ForeName>
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<AffiliationInfo><Affiliation>School of Public Health, Georgia State University, Atlanta, Georgia, USA.</Affiliation>
</AffiliationInfo>
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<ForeName>Yuichiro</ForeName>
<Initials>Y</Initials>
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<tree><country name="Japon"><region name="Région de Kantō"><name sortKey="Mizumoto, Kenji" sort="Mizumoto, Kenji" uniqKey="Mizumoto K" first="Kenji" last="Mizumoto">Kenji Mizumoto</name>
</region>
<name sortKey="Miyamatsu, Yuichiro" sort="Miyamatsu, Yuichiro" uniqKey="Miyamatsu Y" first="Yuichiro" last="Miyamatsu">Yuichiro Miyamatsu</name>
<name sortKey="Nishiura, Hiroshi" sort="Nishiura, Hiroshi" uniqKey="Nishiura H" first="Hiroshi" last="Nishiura">Hiroshi Nishiura</name>
<name sortKey="Saitoh, Masaya" sort="Saitoh, Masaya" uniqKey="Saitoh M" first="Masaya" last="Saitoh">Masaya Saitoh</name>
</country>
<country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Chowell, Gerardo" sort="Chowell, Gerardo" uniqKey="Chowell G" first="Gerardo" last="Chowell">Gerardo Chowell</name>
</region>
</country>
</tree>
</affiliations>
</record>
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