Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response.
Identifieur interne : 001043 ( PubMed/Checkpoint ); précédent : 001042; suivant : 001044Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response.
Auteurs : E. Kindler [Suisse] ; V. Thiel [Suisse] ; F. Weber [Allemagne]Source :
- Advances in virus research [ 1557-8399 ] ; 2016.
Descripteurs français
- KwdFr :
- ARN double brin (génétique), ARN double brin (immunologie), ARN viral (génétique), ARN viral (immunologie), Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Coronavirus du syndrome respiratoire du Moyen-Orient (pathogénicité), Facteurs de transcription STAT (génétique), Facteurs de transcription STAT (immunologie), Humains, Immunité innée, Infections à coronavirus (anatomopathologie), Infections à coronavirus (immunologie), Infections à coronavirus (virologie), Interféron alpha (génétique), Interféron alpha (immunologie), Interféron bêta (génétique), Interféron bêta (immunologie), Interféron gamma (génétique), Interféron gamma (immunologie), Janus kinase 1 (génétique), Janus kinase 1 (immunologie), Protéines virales (génétique), Protéines virales (immunologie), Régulation de l'expression des gènes, Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (immunologie), Syndrome respiratoire aigu sévère (virologie), Transduction du signal, Virus du SRAS (génétique), Virus du SRAS (immunologie), Virus du SRAS (pathogénicité), Échappement immunitaire.
- MESH :
- anatomopathologie : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- génétique : ARN double brin, ARN viral, Coronavirus du syndrome respiratoire du Moyen-Orient, Facteurs de transcription STAT, Interféron alpha, Interféron bêta, Interféron gamma, Janus kinase 1, Protéines virales, Virus du SRAS.
- immunologie : ARN double brin, ARN viral, Coronavirus du syndrome respiratoire du Moyen-Orient, Facteurs de transcription STAT, Infections à coronavirus, Interféron alpha, Interféron bêta, Interféron gamma, Janus kinase 1, Protéines virales, Syndrome respiratoire aigu sévère, Virus du SRAS.
- pathogénicité : Coronavirus du syndrome respiratoire du Moyen-Orient, Virus du SRAS.
- virologie : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- Humains, Immunité innée, Régulation de l'expression des gènes, Transduction du signal, Échappement immunitaire.
English descriptors
- KwdEn :
- Coronavirus Infections (immunology), Coronavirus Infections (pathology), Coronavirus Infections (virology), Gene Expression Regulation, Humans, Immune Evasion, Immunity, Innate, Interferon-alpha (genetics), Interferon-alpha (immunology), Interferon-beta (genetics), Interferon-beta (immunology), Interferon-gamma (genetics), Interferon-gamma (immunology), Janus Kinase 1 (genetics), Janus Kinase 1 (immunology), Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (immunology), Middle East Respiratory Syndrome Coronavirus (pathogenicity), RNA, Double-Stranded (genetics), RNA, Double-Stranded (immunology), RNA, Viral (genetics), RNA, Viral (immunology), SARS Virus (genetics), SARS Virus (immunology), SARS Virus (pathogenicity), STAT Transcription Factors (genetics), STAT Transcription Factors (immunology), Severe Acute Respiratory Syndrome (immunology), Severe Acute Respiratory Syndrome (pathology), Severe Acute Respiratory Syndrome (virology), Signal Transduction, Viral Proteins (genetics), Viral Proteins (immunology).
- MESH :
- chemical , genetics : Interferon-alpha, Interferon-beta, Interferon-gamma, Janus Kinase 1, RNA, Double-Stranded, RNA, Viral, STAT Transcription Factors, Viral Proteins.
- genetics : Middle East Respiratory Syndrome Coronavirus, SARS Virus.
- immunology : Coronavirus Infections, Interferon-alpha, Interferon-beta, Interferon-gamma, Janus Kinase 1, Middle East Respiratory Syndrome Coronavirus, RNA, Double-Stranded, RNA, Viral, SARS Virus, STAT Transcription Factors, Severe Acute Respiratory Syndrome, Viral Proteins.
- pathogenicity : Middle East Respiratory Syndrome Coronavirus, SARS Virus.
- pathology : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- virology : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- Gene Expression Regulation, Humans, Immune Evasion, Immunity, Innate, Signal Transduction.
Abstract
Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are the most severe coronavirus (CoV)-associated diseases in humans. The causative agents, SARS-CoV and MERS-CoV, are of zoonotic origin but may be transmitted to humans, causing severe and often fatal respiratory disease in their new host. The two coronaviruses are thought to encode an unusually large number of factors that allow them to thrive and replicate in the presence of efficient host defense mechanisms, especially the antiviral interferon system. Here, we review the recent progress in our understanding of the strategies that highly pathogenic coronaviruses employ to escape, dampen, or block the antiviral interferon response in human cells.
DOI: 10.1016/bs.aivir.2016.08.006
PubMed: 27712625
Affiliations:
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pubmed:27712625Le document en format XML
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type="abstract" xml:lang="en">Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are the most severe coronavirus (CoV)-associated diseases in humans. The causative agents, SARS-CoV and MERS-CoV, are of zoonotic origin but may be transmitted to humans, causing severe and often fatal respiratory disease in their new host. The two coronaviruses are thought to encode an unusually large number of factors that allow them to thrive and replicate in the presence of efficient host defense mechanisms, especially the antiviral interferon system. Here, we review the recent progress in our understanding of the strategies that highly pathogenic coronaviruses employ to escape, dampen, or block the antiviral interferon response in human cells.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27712625</PMID><DateCompleted><Year>2017</Year><Month>01</Month><Day>11</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>07</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1557-8399</ISSN><JournalIssue CitedMedium="Internet"><Volume>96</Volume><PubDate><Year>2016</Year></PubDate></JournalIssue><Title>Advances in virus research</Title><ISOAbbreviation>Adv. Virus Res.</ISOAbbreviation></Journal><ArticleTitle>Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response.</ArticleTitle><Pagination><MedlinePgn>219-243</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0065-3527(16)30045-8</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/bs.aivir.2016.08.006</ELocationID><Abstract><AbstractText>Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are the most severe coronavirus (CoV)-associated diseases in humans. The causative agents, SARS-CoV and MERS-CoV, are of zoonotic origin but may be transmitted to humans, causing severe and often fatal respiratory disease in their new host. The two coronaviruses are thought to encode an unusually large number of factors that allow them to thrive and replicate in the presence of efficient host defense mechanisms, especially the antiviral interferon system. Here, we review the recent progress in our understanding of the strategies that highly pathogenic coronaviruses employ to escape, dampen, or block the antiviral interferon response in human cells.</AbstractText><CopyrightInformation>© 2016 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kindler</LastName><ForeName>E</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>University of Bern, Bern, Switzerland; Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thiel</LastName><ForeName>V</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>University of Bern, Bern, Switzerland; Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weber</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Institute of Virology, Faculty of Veterinary Medicine, Justus Liebig University Giessen, Giessen, Germany. Electronic address: friedemann.weber@vetmed.uni-giessen.de.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>09</Month><Day>09</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Adv Virus Res</MedlineTA><NlmUniqueID>0370441</NlmUniqueID><ISSNLinking>0065-3527</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D016898">Interferon-alpha</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012330">RNA, Double-Stranded</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012367">RNA, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D050791">STAT Transcription Factors</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014764">Viral Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>77238-31-4</RegistryNumber><NameOfSubstance UI="D016899">Interferon-beta</NameOfSubstance></Chemical><Chemical><RegistryNumber>82115-62-6</RegistryNumber><NameOfSubstance UI="D007371">Interferon-gamma</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.7.10.2</RegistryNumber><NameOfSubstance UI="C507904">JAK1 protein, human</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.7.10.2</RegistryNumber><NameOfSubstance UI="D053613">Janus Kinase 1</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005786" MajorTopicYN="N">Gene Expression Regulation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D057131" MajorTopicYN="Y">Immune Evasion</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007113" MajorTopicYN="N">Immunity, Innate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016898" MajorTopicYN="N">Interferon-alpha</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016899" MajorTopicYN="N">Interferon-beta</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007371" MajorTopicYN="N">Interferon-gamma</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053613" MajorTopicYN="N">Janus Kinase 1</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D065207" MajorTopicYN="N">Middle East Respiratory Syndrome Coronavirus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012330" MajorTopicYN="N">RNA, Double-Stranded</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012367" MajorTopicYN="N">RNA, Viral</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D050791" MajorTopicYN="N">STAT Transcription Factors</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" 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last="Kindler">E. 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