MersV1, PubMed, Checkpoint, bibRecord, 000041

Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses.

Identifieur interne : 000041 ( PubMed/Checkpoint ); précédent : 000040; suivant : 000042

Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses.

Auteurs : Sean Ekins [Oman] ; Peter B. Madrid [États-Unis]

Source :

Antimicrobial agents and chemotherapy [ 1098-6596 ] ; 2020.

RBID : pubmed:32205350

Abstract

Tilorone is a 50-year-old synthetic small-molecule compound with antiviral activity that is proposed to induce interferon after oral administration. This drug is used as a broad-spectrum antiviral in several countries of the Russian Federation. We have recently described activity in vitro and in vivo against the Ebola Virus. After a broad screening of additional viruses, we now describe in vitro activity against Chikungunya virus (CHIK) and Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).

DOI: 10.1128/AAC.00440-20
PubMed: 32205350

Affiliations:

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pubmed:32205350

Le document en format XML

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<front><div type="abstract" xml:lang="en">Tilorone is a 50-year-old synthetic small-molecule compound with antiviral activity that is proposed to induce interferon after oral administration. This drug is used as a broad-spectrum antiviral in several countries of the Russian Federation. We have recently described activity <i>in vitro</i>
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 activity against Chikungunya virus (CHIK) and Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).</div>
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 and <i>in vivo</i>
 against the Ebola Virus. After a broad screening of additional viruses, we now describe <i>in vitro</i>
 activity against Chikungunya virus (CHIK) and Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).</AbstractText>
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Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses.

Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

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Pour générer des pages wiki