Overview of the CSIRO Australian Animal Health Laboratory
Identifieur interne : 001373 ( Pmc/Curation ); précédent : 001372; suivant : 001374Overview of the CSIRO Australian Animal Health Laboratory
Auteurs : John LowenthalSource :
- Journal of Infection and Public Health [ 1876-0341 ] ; 2016.
Abstract
Emerging infectious diseases arising from livestock and wildlife pose serious threats to global human health, as shown by a series of continuous outbreaks involving highly pathogenic influenza, SARS, Ebola and MERS. The risk of pandemics and bioterrorism threats is ever present and growing, but our ability to combat them is limited by the lack of available vaccines, therapeutics and rapid diagnostics. The use of high bio-containment facilities, such as the CSIRO Australian Animal Health Laboratory, plays a key role studying these dangerous pathogens and facilitates the development of countermeasures. To combat diseases like MERS, we must take a holistic approach that involves the development of early biomarkers of infection, a suite of treatment options (vaccines, anti-viral drugs and antibody therapeutics) and appropriate animal models to test the safety and efficacy of candidate treatments.
Url:
DOI: 10.1016/j.jiph.2016.04.007
PubMed: 27118215
PubMed Central: 7102798
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<front><div type="abstract" xml:lang="en"><title>Summary</title>
<p>Emerging infectious diseases arising from livestock and wildlife pose serious threats to global human health, as shown by a series of continuous outbreaks involving highly pathogenic influenza, SARS, Ebola and MERS. The risk of pandemics and bioterrorism threats is ever present and growing, but our ability to combat them is limited by the lack of available vaccines, therapeutics and rapid diagnostics. The use of high bio-containment facilities, such as the CSIRO Australian Animal Health Laboratory, plays a key role studying these dangerous pathogens and facilitates the development of countermeasures. To combat diseases like MERS, we must take a holistic approach that involves the development of early biomarkers of infection, a suite of treatment options (vaccines, anti-viral drugs and antibody therapeutics) and appropriate animal models to test the safety and efficacy of candidate treatments.</p>
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<author><name sortKey="Levy, M A" uniqKey="Levy M">M.A. Levy</name>
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<author><name sortKey="Storeygard, A" uniqKey="Storeygard A">A. Storeygard</name>
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<author><name sortKey="Balk, D" uniqKey="Balk D">D. Balk</name>
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<author><name sortKey="Gittleman, J L" uniqKey="Gittleman J">J.L. Gittleman</name>
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<author><name sortKey="Feng, Y R" uniqKey="Feng Y">Y.R. Feng</name>
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<author><name sortKey="Haining, J" uniqKey="Haining J">J. Haining</name>
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<author><name sortKey="Wada, J" uniqKey="Wada J">J. Wada</name>
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<author><name sortKey="Bollinger, L" uniqKey="Bollinger L">L. Bollinger</name>
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<author><name sortKey="Jahrling, P B" uniqKey="Jahrling P">P.B. Jahrling</name>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Infect Public Health</journal-id>
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<journal-title-group><journal-title>Journal of Infection and Public Health</journal-title>
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<article-id pub-id-type="doi">10.1016/j.jiph.2016.04.007</article-id>
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<contrib-group><contrib contrib-type="author" id="aut0005"><name><surname>Lowenthal</surname>
<given-names>John</given-names>
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<email>john.lowenthal@csiro.au</email>
<xref rid="cor0005" ref-type="corresp">⁎</xref>
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<aff id="aff0005">Emerging Infectious Diseases Program, CSIRO Health and Biosecurity, Australia</aff>
<author-notes><corresp id="cor0005"><label>⁎</label>
Correspondence to: Emerging Infectious Diseases Program, CSIRO Health and Biosecurity Flagship, Australian Animal Health Laboratory, Australia. Tel.: +61 3 5227 5759; fax: +61 3 5227 5531. <email>john.lowenthal@csiro.au</email>
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<pub-date pub-type="pmc-release"><day>24</day>
<month>4</month>
<year>2016</year>
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<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><season>May-Jun</season>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub"><day>24</day>
<month>4</month>
<year>2016</year>
</pub-date>
<volume>9</volume>
<issue>3</issue>
<fpage>236</fpage>
<lpage>239</lpage>
<history><date date-type="received"><day>21</day>
<month>3</month>
<year>2016</year>
</date>
<date date-type="rev-recd"><day>8</day>
<month>4</month>
<year>2016</year>
</date>
<date date-type="accepted"><day>12</day>
<month>4</month>
<year>2016</year>
</date>
</history>
<permissions><copyright-statement>© 2016 King Saud Bin Abdulaziz University for Health Sciences. Production and hosting by Elsevier Limited.</copyright-statement>
<copyright-year>2016</copyright-year>
<copyright-holder>King Saud Bin Abdulaziz University for Health Sciences</copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract id="abs0005"><title>Summary</title>
<p>Emerging infectious diseases arising from livestock and wildlife pose serious threats to global human health, as shown by a series of continuous outbreaks involving highly pathogenic influenza, SARS, Ebola and MERS. The risk of pandemics and bioterrorism threats is ever present and growing, but our ability to combat them is limited by the lack of available vaccines, therapeutics and rapid diagnostics. The use of high bio-containment facilities, such as the CSIRO Australian Animal Health Laboratory, plays a key role studying these dangerous pathogens and facilitates the development of countermeasures. To combat diseases like MERS, we must take a holistic approach that involves the development of early biomarkers of infection, a suite of treatment options (vaccines, anti-viral drugs and antibody therapeutics) and appropriate animal models to test the safety and efficacy of candidate treatments.</p>
</abstract>
<kwd-group id="kwd0005"><title>Keywords</title>
<kwd>High-biocontainment</kwd>
<kwd>Emerging infectious diseases</kwd>
<kwd>MERS</kwd>
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