Drivers of MERS-CoV transmission: what do we know?
Identifieur interne : 001322 ( Pmc/Curation ); précédent : 001321; suivant : 001323Drivers of MERS-CoV transmission: what do we know?
Auteurs : Jaffar A. Al-Tawfiq [Arabie saoudite, États-Unis] ; Ziad A. MemishSource :
- Expert Review of Respiratory Medicine [ 1747-6348 ] ; 2016.
Abstract
Middle East Respiratory Syndrome coronavirus (MERS-CoV) emerged in 2012 has since resulted in sporadic cases, intra-familial transmission and major outbreaks in healthcare settings. The clinical picture of MERS-CoV includes asymptomatic infections, mild or moderately symptomatic cases and fatal disease. Transmissions of MERS-CoV within healthcare settings are facilitated by overcrowding, poor compliance with basic infection control measures, unrecognized infections, the superspreaders phenomenon and poor triage systems. The actual contributing factors to the spread of MERS-CoV are yet to be systematically studied, but data to date suggest viral, host and environmental factors play a major role. Here, we summarize the known factors for the diverse transmission of MERS-CoV.
Url:
DOI: 10.1586/17476348.2016.1150784
PubMed: 26848513
PubMed Central: 7103679
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Ziad A. Memish<affiliation><nlm:aff id="AFF0003"><institution>Medical Department, Ministry of Health</institution>
, Riyadh,<country>Kingdom of Saudi Arabia</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Kingdom of Saudi Arabia</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="AFF0004"><institution>College of Medicine, Alfaisal University</institution>
, Riyadh,<country>Kingdom of Saudi Arabia</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Kingdom of Saudi Arabia</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="AFF0004"><institution>College of Medicine, Alfaisal University</institution>
, Riyadh,<country>Kingdom of Saudi Arabia</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Kingdom of Saudi Arabia</wicri:noCountry>
</affiliation>
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<front><div type="abstract" xml:lang="en"><title>ABSTRACT</title>
<p>Middle East Respiratory Syndrome coronavirus (MERS-CoV) emerged in 2012 has since resulted in sporadic cases, intra-familial transmission and major outbreaks in healthcare settings. The clinical picture of MERS-CoV includes asymptomatic infections, mild or moderately symptomatic cases and fatal disease. Transmissions of MERS-CoV within healthcare settings are facilitated by overcrowding, poor compliance with basic infection control measures, unrecognized infections, the superspreaders phenomenon and poor triage systems. The actual contributing factors to the spread of MERS-CoV are yet to be systematically studied, but data to date suggest viral, host and environmental factors play a major role. Here, we summarize the known factors for the diverse transmission of MERS-CoV.</p>
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<pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Expert Rev Respir Med</journal-id>
<journal-id journal-id-type="iso-abbrev">Expert Rev Respir Med</journal-id>
<journal-id journal-id-type="publisher-id">IERX</journal-id>
<journal-id journal-id-type="publisher-id">ierx20</journal-id>
<journal-title-group><journal-title>Expert Review of Respiratory Medicine</journal-title>
</journal-title-group>
<issn pub-type="ppub">1747-6348</issn>
<issn pub-type="epub">1747-6356</issn>
<publisher><publisher-name>Taylor & Francis</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26848513</article-id>
<article-id pub-id-type="pmc">7103679</article-id>
<article-id pub-id-type="publisher-id">1150784</article-id>
<article-id pub-id-type="doi">10.1586/17476348.2016.1150784</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Reviews</subject>
</subj-group>
</article-categories>
<title-group><article-title>Drivers of MERS-CoV transmission: what do we know?</article-title>
<alt-title alt-title-type="running-authors">J. A. AL-TAWFIQ AND Z. A. MEMISH</alt-title>
<alt-title alt-title-type="running-title">EXPERT REVIEW OF RESPIRATORY MEDICINE</alt-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Al-Tawfiq</surname>
<given-names>Jaffar A.</given-names>
</name>
<xref ref-type="aff" rid="AFF0001"><sup>a</sup>
</xref>
<xref ref-type="aff" rid="AFF0002"><sup>b</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Memish</surname>
<given-names>Ziad A.</given-names>
</name>
<xref ref-type="aff" rid="AFF0003"><sup>c</sup>
</xref>
<xref ref-type="aff" rid="AFF0004"><sup>d</sup>
</xref>
<xref ref-type="corresp" rid="AN0001"></xref>
</contrib>
<aff id="AFF0001"><label>a</label>
<institution>Medical Department, Johns Hopkins Aramco Healthcare</institution>
, Dhahran,<country>Saudi Arabia</country>
</aff>
<aff id="AFF0002"><label>b</label>
<institution>Department of Medicine, Indiana University School of Medicine</institution>
, Indianapolis, IN,<country>USA</country>
</aff>
<aff id="AFF0003"><label>c</label>
<institution>Medical Department, Ministry of Health</institution>
, Riyadh,<country>Kingdom of Saudi Arabia</country>
</aff>
<aff id="AFF0004"><label>d</label>
<institution>College of Medicine, Alfaisal University</institution>
, Riyadh,<country>Kingdom of Saudi Arabia</country>
</aff>
</contrib-group>
<author-notes><corresp id="AN0001"><bold>CONTACT</bold>
Ziad A. Memish <email xlink:href="zmemish@yahoo.com">zmemish@yahoo.com</email>
</corresp>
</author-notes>
<pub-date pub-type="collection"><year>2016</year>
</pub-date>
<pub-date pub-type="epub"><day>29</day>
<month>2</month>
<year>2016</year>
</pub-date>
<volume>10</volume>
<issue>3</issue>
<fpage seq="8">331</fpage>
<lpage>338</lpage>
<history><date date-type="received"><day>15</day>
<month>11</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>02</day>
<month>2</month>
<year>2016</year>
</date>
</history>
<permissions><copyright-statement>© 2016 Taylor & Francis</copyright-statement>
<copyright-year>2016</copyright-year>
<copyright-holder>Taylor & Francis</copyright-holder>
<license><license-p>This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:href="IERX_10_1150784.pdf"></self-uri>
<abstract><title>ABSTRACT</title>
<p>Middle East Respiratory Syndrome coronavirus (MERS-CoV) emerged in 2012 has since resulted in sporadic cases, intra-familial transmission and major outbreaks in healthcare settings. The clinical picture of MERS-CoV includes asymptomatic infections, mild or moderately symptomatic cases and fatal disease. Transmissions of MERS-CoV within healthcare settings are facilitated by overcrowding, poor compliance with basic infection control measures, unrecognized infections, the superspreaders phenomenon and poor triage systems. The actual contributing factors to the spread of MERS-CoV are yet to be systematically studied, but data to date suggest viral, host and environmental factors play a major role. Here, we summarize the known factors for the diverse transmission of MERS-CoV.</p>
</abstract>
<kwd-group kwd-group-type="author"><title>KEYWORDS</title>
<kwd>MERS-CoV</kwd>
<kwd>Coronavirus</kwd>
<kwd>Transmission</kwd>
<kwd>Prevention</kwd>
<kwd>Health Care Facilities</kwd>
</kwd-group>
<counts><fig-count count="1"></fig-count>
<table-count count="2"></table-count>
<ref-count count="98"></ref-count>
<page-count count="8"></page-count>
</counts>
</article-meta>
</front>
</pmc>
</record>
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