MERS: emergence of a novel human coronavirus
Identifieur interne : 001298 ( Pmc/Curation ); précédent : 001297; suivant : 001299MERS: emergence of a novel human coronavirus
Auteurs : V Stalin Raj ; Albert Dme Osterhaus ; Ron Am Fouchier ; Bart L. HaagmansSource :
- Current Opinion in Virology [ 1879-6257 ] ; 2014.
Abstract
In 2012 a novel coronavirus emerged in the Middle East region. MERS-CoV causes a severe lower respiratory tract infection in humans. Dromedary camels were found to be positive for MERS-CoV. MERS-CoV chains of transmission in humans do not seem to be self-sustaining. Isolation of MERS patients combined with limiting the zoonotic events may be crucial in controlling the outbreak.
Url:
DOI: 10.1016/j.coviro.2014.01.010
PubMed: 24584035
PubMed Central: 4028407
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">MERS: emergence of a novel human coronavirus</title><author><name sortKey="Raj, V Stalin" sort="Raj, V Stalin" uniqKey="Raj V" first="V Stalin" last="Raj">V Stalin Raj</name></author><author><name sortKey="Osterhaus, Albert Dme" sort="Osterhaus, Albert Dme" uniqKey="Osterhaus A" first="Albert Dme" last="Osterhaus">Albert Dme Osterhaus</name></author><author><name sortKey="Fouchier, Ron Am" sort="Fouchier, Ron Am" uniqKey="Fouchier R" first="Ron Am" last="Fouchier">Ron Am Fouchier</name></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L" last="Haagmans">Bart L. Haagmans</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24584035</idno><idno type="pmc">4028407</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028407</idno><idno type="RBID">PMC:4028407</idno><idno type="doi">10.1016/j.coviro.2014.01.010</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001298</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001298</idno><idno type="wicri:Area/Pmc/Curation">001298</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001298</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">MERS: emergence of a novel human coronavirus</title><author><name sortKey="Raj, V Stalin" sort="Raj, V Stalin" uniqKey="Raj V" first="V Stalin" last="Raj">V Stalin Raj</name></author><author><name sortKey="Osterhaus, Albert Dme" sort="Osterhaus, Albert Dme" uniqKey="Osterhaus A" first="Albert Dme" last="Osterhaus">Albert Dme Osterhaus</name></author><author><name sortKey="Fouchier, Ron Am" sort="Fouchier, Ron Am" uniqKey="Fouchier R" first="Ron Am" last="Fouchier">Ron Am Fouchier</name></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L" last="Haagmans">Bart L. Haagmans</name></author></analytic><series><title level="j">Current Opinion in Virology</title><idno type="ISSN">1879-6257</idno><idno type="eISSN">1879-6265</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">In 2012 a novel coronavirus emerged in the Middle East region.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">MERS-CoV causes a severe lower respiratory tract infection in humans.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">Dromedary camels were found to be positive for MERS-CoV.</p></list-item><list-item id="lsti0020"><label>•</label><p id="par0020">MERS-CoV chains of transmission in humans do not seem to be self-sustaining.</p></list-item><list-item id="lsti0025"><label>•</label><p id="par0025">Isolation of MERS patients combined with limiting the zoonotic events may be crucial in controlling the outbreak.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G. 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Rambaut</name></author><author><name sortKey="Enouf, V" uniqKey="Enouf V">V. Enouf</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S. van der Werf</name></author><author><name sortKey="Ferguson, N M" uniqKey="Ferguson N">N.M. Ferguson</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Curr Opin Virol</journal-id><journal-id journal-id-type="iso-abbrev">Curr Opin Virol</journal-id><journal-title-group><journal-title>Current Opinion in Virology</journal-title></journal-title-group><issn pub-type="ppub">1879-6257</issn><issn pub-type="epub">1879-6265</issn><publisher><publisher-name>Elsevier B.V.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24584035</article-id><article-id pub-id-type="pmc">4028407</article-id><article-id pub-id-type="publisher-id">S1879-6257(14)00011-X</article-id><article-id pub-id-type="doi">10.1016/j.coviro.2014.01.010</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>MERS: emergence of a novel human coronavirus</article-title></title-group><contrib-group><contrib contrib-type="author" id="aut0005"><name><surname>Raj</surname><given-names>V Stalin</given-names></name></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Osterhaus</surname><given-names>Albert DME</given-names></name></contrib><contrib contrib-type="author" id="aut0015"><name><surname>Fouchier</surname><given-names>Ron AM</given-names></name></contrib><contrib contrib-type="author" id="aut0020"><name><surname>Haagmans</surname><given-names>Bart L</given-names></name><email>b.haagmans@erasmusmc.nl</email></contrib></contrib-group><aff id="aff0005">Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands</aff><pub-date pub-type="pmc-release"><day>28</day><month>2</month><year>2014</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>4</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>2</month><year>2014</year></pub-date><volume>5</volume><fpage>58</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright © 2014 Elsevier B.V. All rights reserved.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder>Elsevier B.V.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract abstract-type="author-highlights" id="abs0005"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">In 2012 a novel coronavirus emerged in the Middle East region.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">MERS-CoV causes a severe lower respiratory tract infection in humans.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">Dromedary camels were found to be positive for MERS-CoV.</p></list-item><list-item id="lsti0020"><label>•</label><p id="par0020">MERS-CoV chains of transmission in humans do not seem to be self-sustaining.</p></list-item><list-item id="lsti0025"><label>•</label><p id="par0025">Isolation of MERS patients combined with limiting the zoonotic events may be crucial in controlling the outbreak.</p></list-item></list></p></abstract><abstract id="abs0010"><p>A novel coronavirus (CoV) that causes a severe lower respiratory tract infection in humans, emerged in the Middle East region in 2012. This virus, named Middle East respiratory syndrome (MERS)-CoV, is phylogenetically related to bat CoVs, but other animal species like dromedary camels may potentially act as intermediate hosts by spreading the virus to humans. Although human to human transmission has been demonstrated, analysis of human MERS clusters indicated that chains of transmission were not self-sustaining, especially when infection control was implemented. Thus, timely identification of new MERS cases followed by their quarantine, combined with measures to limit spread of the virus from the (intermediate) host to humans, may be crucial in controlling the outbreak of this emerging CoV.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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