Infectious MERS-CoV Isolated From a Mildly Ill Patient, Saudi Arabia
Identifieur interne : 000732 ( Pmc/Curation ); précédent : 000731; suivant : 000733Infectious MERS-CoV Isolated From a Mildly Ill Patient, Saudi Arabia
Auteurs : Hail M. Al-Abdely [Arabie saoudite] ; Claire M. Midgley [Géorgie (pays)] ; Abdulrahim M. Alkhamis [Arabie saoudite] ; Glen R. Abedi [Géorgie (pays)] ; Azaibi Tamin [Géorgie (pays)] ; Alison M. Binder [Géorgie (pays)] ; Khalid Alanazi [Arabie saoudite] ; Xiaoyan Lu [Géorgie (pays)] ; Osman Abdalla [Arabie saoudite] ; Senthilkumar K. Sakthivel [Géorgie (pays)] ; Mutaz Mohammed [Arabie saoudite] ; Krista Queen [Géorgie (pays)] ; Homoud S. Algarni [Arabie saoudite] ; Yan Li [Géorgie (pays)] ; Suvang Trivedi [Géorgie (pays)] ; Abdullah Algwizani [Arabie saoudite] ; Raafat F. Alhakeem [Arabie saoudite] ; Natalie J. Thornburg [Géorgie (pays)] ; Suxiang Tong [Géorgie (pays)] ; Sameeh S. Ghazal [Arabie saoudite] ; Dean D. Erdman [Géorgie (pays)] ; Abdullah M. Assiri [Arabie saoudite] ; Susan I. Gerber [Géorgie (pays)] ; John T. Watson [Géorgie (pays)]Source :
- Open Forum Infectious Diseases [ 2328-8957 ] ; 2018.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) is associated with a wide range of clinical presentations, from asymptomatic or mildly ill to severe respiratory illness including death. We describe isolation of infectious MERS-CoV from the upper respiratory tract of a mildly ill 27-year-old female in Saudi Arabia 15 days after illness onset.
Url:
DOI: 10.1093/ofid/ofy111
PubMed: 30294617
PubMed Central: 6016420
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Midgley</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Alkhamis, Abdulrahim M" sort="Alkhamis, Abdulrahim M" uniqKey="Alkhamis A" first="Abdulrahim M" last="Alkhamis">Abdulrahim M. Alkhamis</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Abedi, Glen R" sort="Abedi, Glen R" uniqKey="Abedi G" first="Glen R" last="Abedi">Glen R. 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Alhakeem</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Thornburg, Natalie J" sort="Thornburg, Natalie J" uniqKey="Thornburg N" first="Natalie J" last="Thornburg">Natalie J. Thornburg</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Tong, Suxiang" sort="Tong, Suxiang" uniqKey="Tong S" first="Suxiang" last="Tong">Suxiang Tong</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Ghazal, Sameeh S" sort="Ghazal, Sameeh S" uniqKey="Ghazal S" first="Sameeh S" last="Ghazal">Sameeh S. Ghazal</name><affiliation wicri:level="1"><nlm:aff id="AF0003">Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Prince Mohammed Bin Abdulaziz Hospital, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Erdman, Dean D" sort="Erdman, Dean D" uniqKey="Erdman D" first="Dean D" last="Erdman">Dean D. Erdman</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Assiri, Abdullah M" sort="Assiri, Abdullah M" uniqKey="Assiri A" first="Abdullah M" last="Assiri">Abdullah M. Assiri</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. 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Al-Abdely</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Midgley, Claire M" sort="Midgley, Claire M" uniqKey="Midgley C" first="Claire M" last="Midgley">Claire M. Midgley</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Alkhamis, Abdulrahim M" sort="Alkhamis, Abdulrahim M" uniqKey="Alkhamis A" first="Abdulrahim M" last="Alkhamis">Abdulrahim M. Alkhamis</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Abedi, Glen R" sort="Abedi, Glen R" uniqKey="Abedi G" first="Glen R" last="Abedi">Glen R. Abedi</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Binder, Alison M" sort="Binder, Alison M" uniqKey="Binder A" first="Alison M" last="Binder">Alison M. Binder</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Alanazi, Khalid" sort="Alanazi, Khalid" uniqKey="Alanazi K" first="Khalid" last="Alanazi">Khalid Alanazi</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Lu, Xiaoyan" sort="Lu, Xiaoyan" uniqKey="Lu X" first="Xiaoyan" last="Lu">Xiaoyan Lu</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Abdalla, Osman" sort="Abdalla, Osman" uniqKey="Abdalla O" first="Osman" last="Abdalla">Osman Abdalla</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Sakthivel, Senthilkumar K" sort="Sakthivel, Senthilkumar K" uniqKey="Sakthivel S" first="Senthilkumar K" last="Sakthivel">Senthilkumar K. Sakthivel</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Mohammed, Mutaz" sort="Mohammed, Mutaz" uniqKey="Mohammed M" first="Mutaz" last="Mohammed">Mutaz Mohammed</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Queen, Krista" sort="Queen, Krista" uniqKey="Queen K" first="Krista" last="Queen">Krista Queen</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Algarni, Homoud S" sort="Algarni, Homoud S" uniqKey="Algarni H" first="Homoud S" last="Algarni">Homoud S. Algarni</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Trivedi, Suvang" sort="Trivedi, Suvang" uniqKey="Trivedi S" first="Suvang" last="Trivedi">Suvang Trivedi</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Algwizani, Abdullah" sort="Algwizani, Abdullah" uniqKey="Algwizani A" first="Abdullah" last="Algwizani">Abdullah Algwizani</name><affiliation wicri:level="1"><nlm:aff id="AF0003">Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Prince Mohammed Bin Abdulaziz Hospital, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Alhakeem, Raafat F" sort="Alhakeem, Raafat F" uniqKey="Alhakeem R" first="Raafat F" last="Alhakeem">Raafat F. Alhakeem</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Thornburg, Natalie J" sort="Thornburg, Natalie J" uniqKey="Thornburg N" first="Natalie J" last="Thornburg">Natalie J. Thornburg</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Tong, Suxiang" sort="Tong, Suxiang" uniqKey="Tong S" first="Suxiang" last="Tong">Suxiang Tong</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Ghazal, Sameeh S" sort="Ghazal, Sameeh S" uniqKey="Ghazal S" first="Sameeh S" last="Ghazal">Sameeh S. Ghazal</name><affiliation wicri:level="1"><nlm:aff id="AF0003">Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Prince Mohammed Bin Abdulaziz Hospital, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Erdman, Dean D" sort="Erdman, Dean D" uniqKey="Erdman D" first="Dean D" last="Erdman">Dean D. Erdman</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Assiri, Abdullah M" sort="Assiri, Abdullah M" uniqKey="Assiri A" first="Abdullah M" last="Assiri">Abdullah M. Assiri</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Ministry of Health, Riyadh, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Ministry of Health, Riyadh</wicri:regionArea></affiliation></author><author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Watson, John T" sort="Watson, John T" uniqKey="Watson J" first="John T" last="Watson">John T. Watson</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author></analytic><series><title level="j">Open Forum Infectious Diseases</title><idno type="eISSN">2328-8957</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>Middle East respiratory syndrome coronavirus (MERS-CoV) is associated with a wide range of clinical presentations, from asymptomatic or mildly ill to severe respiratory illness including death. We describe isolation of infectious MERS-CoV from the upper respiratory tract of a mildly ill 27-year-old female in Saudi Arabia 15 days after illness onset.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Alraddadi, Bm" uniqKey="Alraddadi B">BM Alraddadi</name></author><author><name sortKey="Watson, Jt" uniqKey="Watson J">JT Watson</name></author><author><name sortKey="Almarashi, A" uniqKey="Almarashi A">A Almarashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name></author><author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A McGeer</name></author><author><name sortKey="Perl, Tm" uniqKey="Perl T">TM Perl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B Meyer</name></author><author><name sortKey="Muller, Ma" uniqKey="Muller M">MA Müller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oboho, Ik" uniqKey="Oboho I">IK Oboho</name></author><author><name sortKey="Tomczyk, Sm" uniqKey="Tomczyk S">SM Tomczyk</name></author><author><name sortKey="Al Asmari, Am" uniqKey="Al Asmari A">AM Al-Asmari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Omrani, As" uniqKey="Omrani A">AS Omrani</name></author><author><name sortKey="Matin, Ma" uniqKey="Matin M">MA Matin</name></author><author><name sortKey="Haddad, Q" uniqKey="Haddad Q">Q Haddad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alfaraj, Sh" uniqKey="Alfaraj S">SH Alfaraj</name></author><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name></author><author><name sortKey="Altuwaijri, Ta" uniqKey="Altuwaijri T">TA Altuwaijri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Hosani, Fi" uniqKey="Al Hosani F">FI Al Hosani</name></author><author><name sortKey="Pringle, K" uniqKey="Pringle K">K Pringle</name></author><author><name sortKey="Al Mulla, M" uniqKey="Al Mulla M">M Al Mulla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Gethamy, M" uniqKey="Al Gethamy M">M Al-Gethamy</name></author><author><name sortKey="Corman, Vm" uniqKey="Corman V">VM Corman</name></author><author><name sortKey="Hussain, R" uniqKey="Hussain R">R Hussain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mackay, Im" uniqKey="Mackay I">IM Mackay</name></author><author><name sortKey="Arden, Ke" uniqKey="Arden K">KE Arden</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Corman, Vm" uniqKey="Corman V">VM Corman</name></author><author><name sortKey="Olschl Ger, S" uniqKey="Olschl Ger S">S Ölschläger</name></author><author><name sortKey="Wendtner, Cm" uniqKey="Wendtner C">CM Wendtner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, X" uniqKey="Lu X">X Lu</name></author><author><name sortKey="Whitaker, B" uniqKey="Whitaker B">B Whitaker</name></author><author><name sortKey="Sakthivel, Sk" uniqKey="Sakthivel S">SK Sakthivel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, Am" uniqKey="Assiri A">AM Assiri</name></author><author><name sortKey="Midgley, Cm" uniqKey="Midgley C">CM Midgley</name></author><author><name sortKey="Abedi, Gr" uniqKey="Abedi G">GR Abedi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, Am" uniqKey="Assiri A">AM Assiri</name></author><author><name sortKey="Biggs, Hm" uniqKey="Biggs H">HM Biggs</name></author><author><name sortKey="Abedi, Gr" uniqKey="Abedi G">GR Abedi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yusof, Mf" uniqKey="Yusof M">MF Yusof</name></author><author><name sortKey="Queen, K" uniqKey="Queen K">K Queen</name></author><author><name sortKey="Eltahir, Ym" uniqKey="Eltahir Y">YM Eltahir</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trivedi, S" uniqKey="Trivedi S">S Trivedi</name></author><author><name sortKey="Miao, C" uniqKey="Miao C">C Miao</name></author><author><name sortKey="Al Abdallat, Mm" uniqKey="Al Abdallat M">MM Al-Abdallat</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Moon, Sy" uniqKey="Moon S">SY Moon</name></author><author><name sortKey="Son, Js" uniqKey="Son J">JS Son</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="brief-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Open Forum Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">Open Forum Infect Dis</journal-id><journal-id journal-id-type="publisher-id">ofid</journal-id><journal-title-group><journal-title>Open Forum Infectious Diseases</journal-title></journal-title-group><issn pub-type="epub">2328-8957</issn><publisher><publisher-name>Oxford University Press</publisher-name><publisher-loc>US</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">30294617</article-id><article-id pub-id-type="pmc">6016420</article-id><article-id pub-id-type="doi">10.1093/ofid/ofy111</article-id><article-id pub-id-type="publisher-id">ofy111</article-id><article-categories><subj-group subj-group-type="heading"><subject>Brief Reports</subject></subj-group></article-categories><title-group><article-title>Infectious MERS-CoV Isolated From a Mildly Ill Patient, Saudi Arabia</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Al-Abdely</surname><given-names>Hail M</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="author-notes" rid="fn0001"></xref></contrib><contrib contrib-type="author"><name><surname>Midgley</surname><given-names>Claire M</given-names></name><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="author-notes" rid="fn0001"></xref><xref ref-type="corresp" rid="c1"></xref><pmc-comment>ydk5@cdc.gov </pmc-comment>
</contrib><contrib contrib-type="author"><name><surname>Alkhamis</surname><given-names>Abdulrahim M</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Abedi</surname><given-names>Glen R</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0001-9726-8940</contrib-id><name><surname>Tamin</surname><given-names>Azaibi</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Binder</surname><given-names>Alison M</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Alanazi</surname><given-names>Khalid</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Lu</surname><given-names>Xiaoyan</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Abdalla</surname><given-names>Osman</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Sakthivel</surname><given-names>Senthilkumar K</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Mohammed</surname><given-names>Mutaz</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Queen</surname><given-names>Krista</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Algarni</surname><given-names>Homoud S</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Yan</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Trivedi</surname><given-names>Suvang</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Algwizani</surname><given-names>Abdullah</given-names></name><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Alhakeem</surname><given-names>Raafat F</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0003-3523-3616</contrib-id><name><surname>Thornburg</surname><given-names>Natalie J</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Tong</surname><given-names>Suxiang</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Ghazal</surname><given-names>Sameeh S</given-names></name><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Erdman</surname><given-names>Dean D</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Assiri</surname><given-names>Abdullah M</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Gerber</surname><given-names>Susan I</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Watson</surname><given-names>John T</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib></contrib-group><aff id="AF0001"><label>1</label>Ministry of Health, Riyadh, Saudi Arabia</aff><aff id="AF0002"><label>2</label>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</aff><aff id="AF0003"><label>3</label>Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia</aff><author-notes><fn id="fn0001"><p>Equal contribution</p></fn><corresp id="c1">Correspondence: C. M. Midgley, PhD, MSc, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS A34, Atlanta, GA 30329 (<email>ydk5@cdc.gov</email>).</corresp></author-notes><pub-date pub-type="collection"><month>6</month><year>2018</year></pub-date><pub-date pub-type="epub" iso-8601-date="2018-05-15"><day>15</day><month>5</month><year>2018</year></pub-date><pub-date pub-type="pmc-release"><day>15</day><month>5</month><year>2018</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>5</volume><issue>6</issue><elocation-id>ofy111</elocation-id><history><date date-type="received"><day>06</day><month>12</month><year>2017</year></date><date date-type="accepted"><day>11</day><month>5</month><year>2018</year></date></history><permissions><copyright-statement>Published by Oxford University Press on behalf of Infectious Diseases Society of America 2018.</copyright-statement><copyright-year>2018</copyright-year><license license-type="us-gov"><license-p>This work is written by (a) US Government employee(s) and is in the public domain in the US.</license-p></license><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.</license-p></license></permissions><self-uri xlink:href="ofy111.pdf"></self-uri><abstract><title>Abstract</title><p>Middle East respiratory syndrome coronavirus (MERS-CoV) is associated with a wide range of clinical presentations, from asymptomatic or mildly ill to severe respiratory illness including death. We describe isolation of infectious MERS-CoV from the upper respiratory tract of a mildly ill 27-year-old female in Saudi Arabia 15 days after illness onset.</p></abstract><kwd-group><kwd>asymptomatic</kwd><kwd>MERS</kwd><kwd>mild</kwd><kwd>prolonged detection</kwd><kwd>virus isolation</kwd></kwd-group><funding-group><award-group award-type="grant"><funding-source><named-content content-type="funder-name">Ministry of Health</named-content><named-content content-type="funder-identifier">10.13039/100009647</named-content></funding-source></award-group><award-group award-type="grant"><funding-source><named-content content-type="funder-name">Centers for Disease Control and Prevention</named-content><named-content content-type="funder-identifier">10.13039/100000030</named-content></funding-source></award-group></funding-group><counts><page-count count="4"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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