Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
Identifieur interne : 000693 ( Pmc/Curation ); précédent : 000692; suivant : 000694Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
Auteurs : Kenneth G. Frey ; Cassie L. Redden ; Kimberly A. Bishop-Lilly ; Reed Johnson [États-Unis] ; Lisa E. Hensley [États-Unis] ; Kanakatte Raviprakash [États-Unis] ; Thomas Luke ; Tad Kochel [États-Unis] ; Vishwesh P. Mokashi [États-Unis] ; Gabriel N. Defang [Égypte]Source :
- Genome Announcements [ 2169-8287 ] ; 2014.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus.
Url:
DOI: 10.1128/genomeA.00324-14
PubMed: 24874668
PubMed Central: 4038873
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Bishop-Lilly</name></author><author><name sortKey="Johnson, Reed" sort="Johnson, Reed" uniqKey="Johnson R" first="Reed" last="Johnson">Reed Johnson</name><affiliation wicri:level="1"><nlm:aff id="aff4">National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Hensley, Lisa E" sort="Hensley, Lisa E" uniqKey="Hensley L" first="Lisa E." last="Hensley">Lisa E. Hensley</name><affiliation wicri:level="1"><nlm:aff id="aff4">National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Raviprakash, Kanakatte" sort="Raviprakash, Kanakatte" uniqKey="Raviprakash K" first="Kanakatte" last="Raviprakash">Kanakatte Raviprakash</name><affiliation wicri:level="1"><nlm:aff id="aff3">Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Luke, Thomas" sort="Luke, Thomas" uniqKey="Luke T" first="Thomas" last="Luke">Thomas Luke</name></author><author><name sortKey="Kochel, Tad" sort="Kochel, Tad" uniqKey="Kochel T" first="Tad" last="Kochel">Tad Kochel</name><affiliation wicri:level="1"><nlm:aff id="aff3">Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Mokashi, Vishwesh P" sort="Mokashi, Vishwesh P" uniqKey="Mokashi V" first="Vishwesh P." last="Mokashi">Vishwesh P. Mokashi</name><affiliation wicri:level="1"><nlm:aff id="aff1">Naval Medical Research Center, NMRC-Frederick, Fort Detrick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Naval Medical Research Center, NMRC-Frederick, Fort Detrick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Defang, Gabriel N" sort="Defang, Gabriel N" uniqKey="Defang G" first="Gabriel N." last="Defang">Gabriel N. Defang</name><affiliation wicri:level="1"><nlm:aff id="aff5">Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit 3, Abbassia, Cairo, Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit 3, Abbassia, Cairo</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24874668</idno><idno type="pmc">4038873</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038873</idno><idno type="RBID">PMC:4038873</idno><idno type="doi">10.1128/genomeA.00324-14</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000693</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000693</idno><idno type="wicri:Area/Pmc/Curation">000693</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000693</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells</title><author><name sortKey="Frey, Kenneth G" sort="Frey, Kenneth G" uniqKey="Frey K" first="Kenneth G." last="Frey">Kenneth G. Frey</name></author><author><name sortKey="Redden, Cassie L" sort="Redden, Cassie L" uniqKey="Redden C" first="Cassie L." last="Redden">Cassie L. Redden</name></author><author><name sortKey="Bishop Lilly, Kimberly A" sort="Bishop Lilly, Kimberly A" uniqKey="Bishop Lilly K" first="Kimberly A." last="Bishop-Lilly">Kimberly A. Bishop-Lilly</name></author><author><name sortKey="Johnson, Reed" sort="Johnson, Reed" uniqKey="Johnson R" first="Reed" last="Johnson">Reed Johnson</name><affiliation wicri:level="1"><nlm:aff id="aff4">National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Hensley, Lisa E" sort="Hensley, Lisa E" uniqKey="Hensley L" first="Lisa E." last="Hensley">Lisa E. Hensley</name><affiliation wicri:level="1"><nlm:aff id="aff4">National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Raviprakash, Kanakatte" sort="Raviprakash, Kanakatte" uniqKey="Raviprakash K" first="Kanakatte" last="Raviprakash">Kanakatte Raviprakash</name><affiliation wicri:level="1"><nlm:aff id="aff3">Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Luke, Thomas" sort="Luke, Thomas" uniqKey="Luke T" first="Thomas" last="Luke">Thomas Luke</name></author><author><name sortKey="Kochel, Tad" sort="Kochel, Tad" uniqKey="Kochel T" first="Tad" last="Kochel">Tad Kochel</name><affiliation wicri:level="1"><nlm:aff id="aff3">Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Mokashi, Vishwesh P" sort="Mokashi, Vishwesh P" uniqKey="Mokashi V" first="Vishwesh P." last="Mokashi">Vishwesh P. Mokashi</name><affiliation wicri:level="1"><nlm:aff id="aff1">Naval Medical Research Center, NMRC-Frederick, Fort Detrick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Naval Medical Research Center, NMRC-Frederick, Fort Detrick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Defang, Gabriel N" sort="Defang, Gabriel N" uniqKey="Defang G" first="Gabriel N." last="Defang">Gabriel N. Defang</name><affiliation wicri:level="1"><nlm:aff id="aff5">Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit 3, Abbassia, Cairo, Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit 3, Abbassia, Cairo</wicri:regionArea></affiliation></author></analytic><series><title level="j">Genome Announcements</title><idno type="eISSN">2169-8287</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Genome Announc</journal-id><journal-id journal-id-type="iso-abbrev">Genome Announc</journal-id><journal-id journal-id-type="hwp">ga</journal-id><journal-id journal-id-type="pmc">ga</journal-id><journal-id journal-id-type="publisher-id">GA</journal-id><journal-title-group><journal-title>Genome Announcements</journal-title></journal-title-group><issn pub-type="epub">2169-8287</issn><publisher><publisher-name>American Society for Microbiology</publisher-name><publisher-loc>1752 N St., N.W., Washington, DC</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24874668</article-id><article-id pub-id-type="pmc">4038873</article-id><article-id pub-id-type="publisher-id">genomeA00324-14</article-id><article-id pub-id-type="doi">10.1128/genomeA.00324-14</article-id><article-categories><subj-group subj-group-type="heading"><subject>Viruses</subject></subj-group></article-categories><title-group><article-title>Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Frey</surname><given-names>Kenneth G.</given-names></name><xref ref-type="aff" rid="aff1 aff2"><sup>a,b</sup></xref></contrib><contrib contrib-type="author"><name><surname>Redden</surname><given-names>Cassie L.</given-names></name><xref ref-type="aff" rid="aff1 aff2"><sup>a,b</sup></xref></contrib><contrib contrib-type="author"><name><surname>Bishop-Lilly</surname><given-names>Kimberly A.</given-names></name><xref ref-type="aff" rid="aff1 aff2"><sup>a,b</sup></xref></contrib><contrib contrib-type="author"><name><surname>Johnson</surname><given-names>Reed</given-names></name><xref ref-type="aff" rid="aff4"><sup>d</sup></xref></contrib><contrib contrib-type="author"><name><surname>Hensley</surname><given-names>Lisa E.</given-names></name><xref ref-type="aff" rid="aff4"><sup>d</sup></xref></contrib><contrib contrib-type="author"><name><surname>Raviprakash</surname><given-names>Kanakatte</given-names></name><xref ref-type="aff" rid="aff3"><sup>c</sup></xref></contrib><contrib contrib-type="author"><name><surname>Luke</surname><given-names>Thomas</given-names></name><xref ref-type="aff" rid="aff2 aff3"><sup>b,c</sup></xref></contrib><contrib contrib-type="author"><name><surname>Kochel</surname><given-names>Tad</given-names></name><xref ref-type="aff" rid="aff3"><sup>c</sup></xref></contrib><contrib contrib-type="author"><name><surname>Mokashi</surname><given-names>Vishwesh P.</given-names></name><xref ref-type="aff" rid="aff1"><sup>a</sup></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Defang</surname><given-names>Gabriel N.</given-names></name><xref ref-type="aff" rid="aff5"><sup>e</sup></xref></contrib><aff id="aff1"><label>a</label>Naval Medical Research Center, NMRC-Frederick, Fort Detrick, Maryland, USA</aff><aff id="aff2"><label>b</label>Henry M. Jackson Foundation, Bethesda, Maryland, USA</aff><aff id="aff3"><label>c</label>Naval Medical Research Center, Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA</aff><aff id="aff4"><label>d</label>National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Fort Detrick, Maryland, USA</aff><aff id="aff5"><label>e</label>Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit 3, Abbassia, Cairo, Egypt</aff></contrib-group><author-notes><corresp id="cor1">Address correspondence to Kenneth G. Frey, <email>kenneth.frey@med.navy.mil</email>, or Gabriel N. Defang, <email>gabriel.defang@med.navy.mil</email>.</corresp></author-notes><pub-date pub-type="epub"><day>29</day><month>5</month><year>2014</year></pub-date><pub-date pub-type="collection"><season>May-Jun</season><year>2014</year></pub-date><volume>2</volume><issue>3</issue><elocation-id>e00324-14</elocation-id><history><date date-type="received"><day>27</day><month>3</month><year>2014</year></date><date date-type="accepted"><day>13</day><month>5</month><year>2014</year></date></history><permissions><copyright-statement>Copyright © 2014 Frey et al.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder>Frey et al.</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/3.0/">Creative Commons Attribution 3.0 Unported license</ext-link>.</license-p></license></permissions><self-uri xlink:title="pdf" xlink:type="simple" xlink:href="jga003141323001.pdf"></self-uri><abstract><p>Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus.</p></abstract><counts><page-count count="2"></page-count></counts><custom-meta-group><custom-meta><meta-name>cover-date</meta-name><meta-value>May/June 2014</meta-value></custom-meta><custom-meta><meta-name>access-type</meta-name><meta-value>free</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
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