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Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

Identifieur interne : 000670 ( Pmc/Curation ); précédent : 000669; suivant : 000671

Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

Auteurs : Isabella Eckerle ; Victor M. Corman ; Marcel A. Müller ; Matthias Lenk ; Rainer G. Ulrich ; Christian Drosten

Source :

Emerging Infectious Diseases [ 1080-6040 ] ; 2014.

RBID : PMC:3901466

Abstract

Replicative capacity of Middle East respiratory syndrome coronavirus (MERS-CoV) was assessed in cell lines derived from livestock and peridomestic small mammals on the Arabian Peninsula. Only cell lines originating from goats and camels showed efficient replication of MERS-CoV. These results provide direction in the search for the intermediate host of MERS-CoV.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901466

DOI: 10.3201/eid2002.131182
PubMed: 24457147
PubMed Central: 3901466

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PMC:3901466

Le document en format XML

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<author><name sortKey="Eckerle, Isabella" sort="Eckerle, Isabella" uniqKey="Eckerle I" first="Isabella" last="Eckerle">Isabella Eckerle</name>
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<author><name sortKey="Corman, Victor M" sort="Corman, Victor M" uniqKey="Corman V" first="Victor M." last="Corman">Victor M. Corman</name>
</author>
<author><name sortKey="Muller, Marcel A" sort="Muller, Marcel A" uniqKey="Muller M" first="Marcel A." last="Müller">Marcel A. Müller</name>
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<author><name sortKey="Lenk, Matthias" sort="Lenk, Matthias" uniqKey="Lenk M" first="Matthias" last="Lenk">Matthias Lenk</name>
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<author><name sortKey="Ulrich, Rainer G" sort="Ulrich, Rainer G" uniqKey="Ulrich R" first="Rainer G." last="Ulrich">Rainer G. Ulrich</name>
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<author><name sortKey="Corman, Victor M" sort="Corman, Victor M" uniqKey="Corman V" first="Victor M." last="Corman">Victor M. Corman</name>
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<author><name sortKey="Lenk, Matthias" sort="Lenk, Matthias" uniqKey="Lenk M" first="Matthias" last="Lenk">Matthias Lenk</name>
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<author><name sortKey="Ulrich, Rainer G" sort="Ulrich, Rainer G" uniqKey="Ulrich R" first="Rainer G." last="Ulrich">Rainer G. Ulrich</name>
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<series><title level="j">Emerging Infectious Diseases</title>
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<front><div type="abstract" xml:lang="en"><p>Replicative capacity of Middle East respiratory syndrome coronavirus (MERS-CoV) was assessed in cell lines derived from livestock and peridomestic small mammals on the Arabian Peninsula. Only cell lines originating from goats and camels showed efficient replication of MERS-CoV. These results provide direction in the search for the intermediate host of MERS-CoV.</p>
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  <front><journal-meta><journal-id journal-id-type="nlm-ta">Emerg Infect Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Emerging Infect. Dis</journal-id>
<journal-id journal-id-type="publisher-id">EID</journal-id>
<journal-title-group><journal-title>Emerging Infectious Diseases</journal-title>
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<issn pub-type="ppub">1080-6040</issn>
<issn pub-type="epub">1080-6059</issn>
<publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name>
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<article-meta><article-id pub-id-type="pmid">24457147</article-id>
<article-id pub-id-type="pmc">3901466</article-id>
<article-id pub-id-type="publisher-id">13-1182</article-id>
<article-id pub-id-type="doi">10.3201/eid2002.131182</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Dispatch</subject>
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<title-group><article-title>Replicative Capacity of MERS Coronavirus in Livestock Cell Lines</article-title>
<alt-title alt-title-type="running-head">Replicative Capacity of MERS-CoV in Cell Lines</alt-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Eckerle</surname>
<given-names>Isabella</given-names>
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<contrib contrib-type="author"><name><surname>Corman</surname>
<given-names>Victor M.</given-names>
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<contrib contrib-type="author"><name><surname>Müller</surname>
<given-names>Marcel A.</given-names>
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<contrib contrib-type="author"><name><surname>Lenk</surname>
<given-names>Matthias</given-names>
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<contrib contrib-type="author"><name><surname>Ulrich</surname>
<given-names>Rainer G.</given-names>
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<contrib contrib-type="author" corresp="yes"><name><surname>Drosten</surname>
<given-names>Christian</given-names>
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<aff id="aff1">University of Bonn Medical Centre, Bonn, Germany (I. Eckerle, V.M. Corman, M.A. Müller, C. Drosten);</aff>
<aff id="aff2">Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany (M. Lenk, R.G. Ulrich)</aff>
</contrib-group>
<author-notes><corresp id="cor1">Address for correspondence: Christian Drosten, Institute of Virology, University of Bonn Medical Centre, 53105 Bonn, Germany; email: <email xlink:href="drosten@virology-bonn.de">drosten@virology-bonn.de</email>
</corresp>
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<pub-date pub-type="ppub"><month>2</month>
<year>2014</year>
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<volume>20</volume>
<issue>2</issue>
<fpage>276</fpage>
<lpage>279</lpage>
<abstract><p>Replicative capacity of Middle East respiratory syndrome coronavirus (MERS-CoV) was assessed in cell lines derived from livestock and peridomestic small mammals on the Arabian Peninsula. Only cell lines originating from goats and camels showed efficient replication of MERS-CoV. These results provide direction in the search for the intermediate host of MERS-CoV.</p>
</abstract>
<kwd-group kwd-group-type="author"><title>Keywords: </title>
<kwd>Middle East respiratory syndrome</kwd>
<kwd>MERS</kwd>
<kwd>coronavirus</kwd>
<kwd>livestock</kwd>
<kwd>intermediate host</kwd>
<kwd>zoonosis</kwd>
<kwd>zoonotic</kwd>
<kwd>zoonoses</kwd>
<kwd>viruses</kwd>
<kwd>cell culture</kwd>
<kwd>goats</kwd>
<kwd>camels</kwd>
<kwd>Arabian Peninsula</kwd>
</kwd-group>
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Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

Source :

Abstract

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