A Review of Coronavirus Disease-2019 (COVID-19)
Identifieur interne : 000519 ( Pmc/Curation ); précédent : 000518; suivant : 000520A Review of Coronavirus Disease-2019 (COVID-19)
Auteurs : Tanu SinghalSource :
- Indian Journal of Pediatrics [ 0019-5456 ] ; 2020.
Abstract
There is a new public health crises threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus originated in bats and was transmitted to humans through yet unknown intermediary animals in Wuhan, Hubei province, China in December 2019. There have been around 96,000 reported cases of coronavirus disease 2019 (COVID-2019) and 3300 reported deaths to date (05/03/2020). The disease is transmitted by inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 d. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The disease is mild in most people; in some (usually the elderly and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi organ dysfunction. Many people are asymptomatic. The case fatality rate is estimated to range from 2 to 3%. Diagnosis is by demonstration of the virus in respiratory secretions by special molecular tests. Common laboratory findings include normal/ low white cell counts with elevated C-reactive protein (CRP). The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. Treatment is essentially supportive; role of antiviral agents is yet to be established. Prevention entails home isolation of suspected cases and those with mild illnesses and strict infection control measures at hospitals that include contact and droplet precautions. The virus spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality. The global impact of this new epidemic is yet uncertain.
Url:
DOI: 10.1007/s12098-020-03263-6
PubMed: 32166607
PubMed Central: 7090728
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Review of Coronavirus Disease-2019 (COVID-19)</title><author><name sortKey="Singhal, Tanu" sort="Singhal, Tanu" uniqKey="Singhal T" first="Tanu" last="Singhal">Tanu Singhal</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32166607</idno><idno type="pmc">7090728</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090728</idno><idno type="RBID">PMC:7090728</idno><idno type="doi">10.1007/s12098-020-03263-6</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000519</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000519</idno><idno type="wicri:Area/Pmc/Curation">000519</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000519</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Review of Coronavirus Disease-2019 (COVID-19)</title><author><name sortKey="Singhal, Tanu" sort="Singhal, Tanu" uniqKey="Singhal T" first="Tanu" last="Singhal">Tanu Singhal</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Indian Journal of Pediatrics</title><idno type="ISSN">0019-5456</idno><idno type="eISSN">0973-7693</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">There is a new public health crises threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus originated in bats and was transmitted to humans through yet unknown intermediary animals in Wuhan, Hubei province, China in December 2019. There have been around 96,000 reported cases of coronavirus disease 2019 (COVID-2019) and 3300 reported deaths to date (05/03/2020). The disease is transmitted by inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 d. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The disease is mild in most people; in some (usually the elderly and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi organ dysfunction. Many people are asymptomatic. The case fatality rate is estimated to range from 2 to 3%. Diagnosis is by demonstration of the virus in respiratory secretions by special molecular tests. Common laboratory findings include normal/ low white cell counts with elevated C-reactive protein (CRP). The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. Treatment is essentially supportive; role of antiviral agents is yet to be established. Prevention entails home isolation of suspected cases and those with mild illnesses and strict infection control measures at hospitals that include contact and droplet precautions. The virus spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality. The global impact of this new epidemic is yet uncertain.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wang, Chen" uniqKey="Wang C">Chen Wang</name></author><author><name sortKey="Horby, Peter W" uniqKey="Horby P">Peter W Horby</name></author><author><name sortKey="Hayden, Frederick G" uniqKey="Hayden F">Frederick G Hayden</name></author><author><name sortKey="Gao, George F" uniqKey="Gao G">George F Gao</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chan Yeung, M" uniqKey="Chan Yeung M">M Chan-Yeung</name></author><author><name sortKey="Xu, Rh" uniqKey="Xu R">RH Xu</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C Huang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Indian J Pediatr</journal-id><journal-id journal-id-type="iso-abbrev">Indian J Pediatr</journal-id><journal-title-group><journal-title>Indian Journal of Pediatrics</journal-title></journal-title-group><issn pub-type="ppub">0019-5456</issn><issn pub-type="epub">0973-7693</issn><publisher><publisher-name>Springer India</publisher-name><publisher-loc>New Delhi</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">32166607</article-id><article-id pub-id-type="pmc">7090728</article-id><article-id pub-id-type="publisher-id">3263</article-id><article-id pub-id-type="doi">10.1007/s12098-020-03263-6</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>A Review of Coronavirus Disease-2019 (COVID-19)</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Singhal</surname><given-names>Tanu</given-names></name><address><email>tanusinghal@yahoo.com</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.459725.8</institution-id><institution>Department of Pediatrics and Infectious Disease,</institution><institution>Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute,</institution></institution-wrap>Mumbai, India</aff></contrib-group><pub-date pub-type="epub"><day>13</day><month>3</month><year>2020</year></pub-date><pub-date pub-type="ppub"><year>2020</year></pub-date><volume>87</volume><issue>4</issue><fpage>281</fpage><lpage>286</lpage><history><date date-type="received"><day>23</day><month>2</month><year>2020</year></date><date date-type="accepted"><day>25</day><month>2</month><year>2020</year></date></history><permissions><copyright-statement>© Dr. K C Chaudhuri Foundation 2020</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><p id="Par1">There is a new public health crises threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus originated in bats and was transmitted to humans through yet unknown intermediary animals in Wuhan, Hubei province, China in December 2019. There have been around 96,000 reported cases of coronavirus disease 2019 (COVID-2019) and 3300 reported deaths to date (05/03/2020). The disease is transmitted by inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 d. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The disease is mild in most people; in some (usually the elderly and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi organ dysfunction. Many people are asymptomatic. The case fatality rate is estimated to range from 2 to 3%. Diagnosis is by demonstration of the virus in respiratory secretions by special molecular tests. Common laboratory findings include normal/ low white cell counts with elevated C-reactive protein (CRP). The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. Treatment is essentially supportive; role of antiviral agents is yet to be established. Prevention entails home isolation of suspected cases and those with mild illnesses and strict infection control measures at hospitals that include contact and droplet precautions. The virus spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality. The global impact of this new epidemic is yet uncertain.</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>2019-nCOV</kwd><kwd>SARS-CoV-2</kwd><kwd>COVID-19</kwd><kwd>Pneumonia</kwd><kwd>Review</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Dr. K C Chaudhuri Foundation 2020</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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