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Antibody Response and Disease Severity in Healthcare Worker MERS Survivors

Identifieur interne : 000063 ( Pmc/Curation ); précédent : 000062; suivant : 000064

Antibody Response and Disease Severity in Healthcare Worker MERS Survivors

Auteurs : Abeer N. Alshukairi ; Imran Khalid ; Waleed A. Ahmed ; Ashraf M. Dada ; Daniyah T. Bayumi ; Laut S. Malic ; Sahar Althawadi ; Kim Ignacio ; Hanadi S. Alsalmi ; Hail M. Al-Abdely ; Ghassan Y. Wali ; Ismael A. Qushmaq ; Basem M. Alraddadi ; Stanley Perlman

Source :

Emerging Infectious Diseases [ 1080-6040 ] ; 2016.

RBID : PMC:4880093

Abstract

We studied antibody response in 9 healthcare workers in Jeddah, Saudi Arabia, who survived Middle East respiratory syndrome, by using serial ELISA and indirect immunofluorescence assay testing. Among patients who had experienced severe pneumonia, antibody was detected for >18 months after infection. Antibody longevity was more variable in patients who had experienced milder disease.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880093

DOI: 10.3201/eid2206.160010
PubMed: 27192543
PubMed Central: 4880093

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Le document en format XML

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</author>
<author><name sortKey="Khalid, Imran" sort="Khalid, Imran" uniqKey="Khalid I" first="Imran" last="Khalid">Imran Khalid</name>
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<author><name sortKey="Ahmed, Waleed A" sort="Ahmed, Waleed A" uniqKey="Ahmed W" first="Waleed A." last="Ahmed">Waleed A. Ahmed</name>
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<author><name sortKey="Dada, Ashraf M" sort="Dada, Ashraf M" uniqKey="Dada A" first="Ashraf M." last="Dada">Ashraf M. Dada</name>
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<series><title level="j">Emerging Infectious Diseases</title>
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<front><div type="abstract" xml:lang="en"><p>We studied antibody response in 9 healthcare workers in Jeddah, Saudi Arabia, who survived Middle East respiratory syndrome, by using serial ELISA and indirect immunofluorescence assay testing. Among patients who had experienced severe pneumonia, antibody was detected for <underline>></underline>
18 months after infection. Antibody longevity was more variable in patients who had experienced milder disease.</p>
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  <front><journal-meta><journal-id journal-id-type="nlm-ta">Emerg Infect Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Emerging Infect. Dis</journal-id>
<journal-id journal-id-type="publisher-id">EID</journal-id>
<journal-title-group><journal-title>Emerging Infectious Diseases</journal-title>
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<issn pub-type="ppub">1080-6040</issn>
<issn pub-type="epub">1080-6059</issn>
<publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name>
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<article-meta><article-id pub-id-type="pmid">27192543</article-id>
<article-id pub-id-type="pmc">4880093</article-id>
<article-id pub-id-type="publisher-id">16-0010</article-id>
<article-id pub-id-type="doi">10.3201/eid2206.160010</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Dispatch</subject>
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<subj-group subj-group-type="article-type"><subject>Dispatch</subject>
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<subj-group subj-group-type="TOC-title"><subject>Antibody Response and Disease Severity in Healthcare Worker MERS Survivors</subject>
</subj-group>
</article-categories>
<title-group><article-title>Antibody Response and Disease Severity in Healthcare Worker MERS Survivors</article-title>
<alt-title alt-title-type="running-head">Antibody Response in MERS Survivors</alt-title>
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<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Alshukairi</surname>
<given-names>Abeer N.</given-names>
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<contrib contrib-type="author"><name><surname>Khalid</surname>
<given-names>Imran</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Ahmed</surname>
<given-names>Waleed A.</given-names>
</name>
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<contrib contrib-type="author"><name><surname>Dada</surname>
<given-names>Ashraf M.</given-names>
</name>
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<contrib contrib-type="author"><name><surname>Bayumi</surname>
<given-names>Daniyah T.</given-names>
</name>
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<contrib contrib-type="author"><name><surname>Malic</surname>
<given-names>Laut S.</given-names>
</name>
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<contrib contrib-type="author"><name><surname>Althawadi</surname>
<given-names>Sahar</given-names>
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<contrib contrib-type="author"><name><surname>Ignacio</surname>
<given-names>Kim</given-names>
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<contrib contrib-type="author"><name><surname>Alsalmi</surname>
<given-names>Hanadi S.</given-names>
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<contrib contrib-type="author"><name><surname>Al-Abdely</surname>
<given-names>Hail M.</given-names>
</name>
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<contrib contrib-type="author"><name><surname>Wali</surname>
<given-names>Ghassan Y.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Qushmaq</surname>
<given-names>Ismael A.</given-names>
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<contrib contrib-type="author"><name><surname>Alraddadi</surname>
<given-names>Basem M.</given-names>
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<contrib contrib-type="author"><name><surname>Perlman</surname>
<given-names>Stanley</given-names>
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<aff id="aff1">King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia (A.N. Alshukairi, I. Khalid, W.A. Ahmed, A.M. Dada, D.T. Bayumi, L.S. Malic, H.S. Alsalmi, G.Y. Wali, I.A. Qushmaq, B.M. Alraddadi);</aff>
<aff id="aff2">King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia (S. Althawadi, K. Ignacio);</aff>
<aff id="aff3">General Directorate of Infection Prevention and Control, Ministry of Health, Riyadh (H.M. Al-Abdely);</aff>
<aff id="aff4">University of Iowa Department of Microbiology, Iowa City, Iowa, USA (S. Perlman)</aff>
</contrib-group>
<author-notes><corresp id="cor1">Address for correspondence: Abeer N. Alshukairi, King Faisal Specialist Hospital and Research Center, Department of Medicine, PO Box 6653, Jeddah 21452, Saudi Arabia; email: <email xlink:href="abeer_sh@doctor.com">abeer_sh@doctor.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>6</month>
<year>2016</year>
</pub-date>
<volume>22</volume>
<issue>6</issue>
<fpage>1113</fpage>
<lpage>1115</lpage>
<abstract><p>We studied antibody response in 9 healthcare workers in Jeddah, Saudi Arabia, who survived Middle East respiratory syndrome, by using serial ELISA and indirect immunofluorescence assay testing. Among patients who had experienced severe pneumonia, antibody was detected for <underline>></underline>
18 months after infection. Antibody longevity was more variable in patients who had experienced milder disease.</p>
</abstract>
<kwd-group kwd-group-type="author"><title>Keywords: </title>
<kwd>antibody</kwd>
<kwd>Middle East respiratory syndrome coronavirus</kwd>
<kwd>MERS-CoV</kwd>
<kwd>ELISA</kwd>
<kwd>indirect immunofluorescence assay</kwd>
<kwd>IFA</kwd>
<kwd>healthcare workers</kwd>
<kwd>immune response</kwd>
<kwd>viruses</kwd>
<kwd>Jeddah</kwd>
<kwd>Saudi Arabia</kwd>
</kwd-group>
</article-meta>
</front>
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</record>

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Antibody Response and Disease Severity in Healthcare Worker MERS Survivors

Antibody Response and Disease Severity in Healthcare Worker MERS Survivors

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