Serveur d'exploration MERS

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MP647OUTCOMES OF HEMODIALYSIS PATIENTS WITH MERS-COV EXPOSURE IN KOREA

Identifieur interne : 000896 ( Pmc/Corpus ); précédent : 000895; suivant : 000897

MP647OUTCOMES OF HEMODIALYSIS PATIENTS WITH MERS-COV EXPOSURE IN KOREA

Auteurs : Young-Ki Lee ; Ajin Cho ; Jong-Woo Yoon ; Hee Jung Jeon ; Ji Won Ryu ; Jung-Woo Noh ; Yoo Jin Choi ; Eun Ji Bae ; Eun Yi Kim ; Da-Wun Jeong ; Yang-Gyun Kim ; Sang-Ho Lee ; Chang-Hee Lee ; Kyung Don Yoo

Source :

RBID : PMC:7107803
Url:
DOI: 10.1093/ndt/gfw198.64
PubMed: NONE
PubMed Central: 7107803

Links to Exploration step

PMC:7107803

Le document en format XML

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OUTCOMES OF HEMODIALYSIS PATIENTS WITH MERS-COV EXPOSURE IN KOREA</title>
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<name sortKey="Jeon, Hee Jung" sort="Jeon, Hee Jung" uniqKey="Jeon H" first="Hee Jung" last="Jeon">Hee Jung Jeon</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
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<name sortKey="Ryu, Ji Won" sort="Ryu, Ji Won" uniqKey="Ryu J" first="Ji Won" last="Ryu">Ji Won Ryu</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
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<name sortKey="Noh, Jung Woo" sort="Noh, Jung Woo" uniqKey="Noh J" first="Jung-Woo" last="Noh">Jung-Woo Noh</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
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<author>
<name sortKey="Choi, Yoo Jin" sort="Choi, Yoo Jin" uniqKey="Choi Y" first="Yoo Jin" last="Choi">Yoo Jin Choi</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
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<name sortKey="Bae, Eun Ji" sort="Bae, Eun Ji" uniqKey="Bae E" first="Eun Ji" last="Bae">Eun Ji Bae</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
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<author>
<name sortKey="Kim, Eun Yi" sort="Kim, Eun Yi" uniqKey="Kim E" first="Eun Yi" last="Kim">Eun Yi Kim</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Jeong, Da Wun" sort="Jeong, Da Wun" uniqKey="Jeong D" first="Da-Wun" last="Jeong">Da-Wun Jeong</name>
<affiliation>
<nlm:aff id="MP647_aff_2">Kyung Hee University at Kangdong, Nephrology, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kim, Yang Gyun" sort="Kim, Yang Gyun" uniqKey="Kim Y" first="Yang-Gyun" last="Kim">Yang-Gyun Kim</name>
<affiliation>
<nlm:aff id="MP647_aff_2">Kyung Hee University at Kangdong, Nephrology, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lee, Sang Ho" sort="Lee, Sang Ho" uniqKey="Lee S" first="Sang-Ho" last="Lee">Sang-Ho Lee</name>
<affiliation>
<nlm:aff id="MP647_aff_2">Kyung Hee University at Kangdong, Nephrology, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lee, Chang Hee" sort="Lee, Chang Hee" uniqKey="Lee C" first="Chang-Hee" last="Lee">Chang-Hee Lee</name>
<affiliation>
<nlm:aff id="MP647_aff_3">Gangeung Medical Center, Anesthesiology, Gangeung, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Yoo, Kyung Don" sort="Yoo, Kyung Don" uniqKey="Yoo K" first="Kyung Don" last="Yoo">Kyung Don Yoo</name>
<affiliation>
<nlm:aff id="MP647_aff_4">Dongguk University Medical Center, Internal Medicine, Gyeongju, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
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<title xml:lang="en" level="a" type="main">MP647
<break></break>
OUTCOMES OF HEMODIALYSIS PATIENTS WITH MERS-COV EXPOSURE IN KOREA</title>
<author>
<name sortKey="Lee, Young Ki" sort="Lee, Young Ki" uniqKey="Lee Y" first="Young-Ki" last="Lee">Young-Ki Lee</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Cho, Ajin" sort="Cho, Ajin" uniqKey="Cho A" first="Ajin" last="Cho">Ajin Cho</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Yoon, Jong Woo" sort="Yoon, Jong Woo" uniqKey="Yoon J" first="Jong-Woo" last="Yoon">Jong-Woo Yoon</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Jeon, Hee Jung" sort="Jeon, Hee Jung" uniqKey="Jeon H" first="Hee Jung" last="Jeon">Hee Jung Jeon</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ryu, Ji Won" sort="Ryu, Ji Won" uniqKey="Ryu J" first="Ji Won" last="Ryu">Ji Won Ryu</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Noh, Jung Woo" sort="Noh, Jung Woo" uniqKey="Noh J" first="Jung-Woo" last="Noh">Jung-Woo Noh</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Choi, Yoo Jin" sort="Choi, Yoo Jin" uniqKey="Choi Y" first="Yoo Jin" last="Choi">Yoo Jin Choi</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bae, Eun Ji" sort="Bae, Eun Ji" uniqKey="Bae E" first="Eun Ji" last="Bae">Eun Ji Bae</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kim, Eun Yi" sort="Kim, Eun Yi" uniqKey="Kim E" first="Eun Yi" last="Kim">Eun Yi Kim</name>
<affiliation>
<nlm:aff id="MP647_aff_1">Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Jeong, Da Wun" sort="Jeong, Da Wun" uniqKey="Jeong D" first="Da-Wun" last="Jeong">Da-Wun Jeong</name>
<affiliation>
<nlm:aff id="MP647_aff_2">Kyung Hee University at Kangdong, Nephrology, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kim, Yang Gyun" sort="Kim, Yang Gyun" uniqKey="Kim Y" first="Yang-Gyun" last="Kim">Yang-Gyun Kim</name>
<affiliation>
<nlm:aff id="MP647_aff_2">Kyung Hee University at Kangdong, Nephrology, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lee, Sang Ho" sort="Lee, Sang Ho" uniqKey="Lee S" first="Sang-Ho" last="Lee">Sang-Ho Lee</name>
<affiliation>
<nlm:aff id="MP647_aff_2">Kyung Hee University at Kangdong, Nephrology, Seoul, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lee, Chang Hee" sort="Lee, Chang Hee" uniqKey="Lee C" first="Chang-Hee" last="Lee">Chang-Hee Lee</name>
<affiliation>
<nlm:aff id="MP647_aff_3">Gangeung Medical Center, Anesthesiology, Gangeung, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Yoo, Kyung Don" sort="Yoo, Kyung Don" uniqKey="Yoo K" first="Kyung Don" last="Yoo">Kyung Don Yoo</name>
<affiliation>
<nlm:aff id="MP647_aff_4">Dongguk University Medical Center, Internal Medicine, Gyeongju, REPUBLIC OF KOREA</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Nephrology Dialysis Transplantation</title>
<idno type="ISSN">0931-0509</idno>
<idno type="eISSN">1460-2385</idno>
<imprint>
<date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
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<pmc article-type="meeting-report">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Nephrol Dial Transplant</journal-id>
<journal-id journal-id-type="iso-abbrev">Nephrol. Dial. Transplant</journal-id>
<journal-id journal-id-type="publisher-id">ndt</journal-id>
<journal-id journal-id-type="hwp">ndt</journal-id>
<journal-title-group>
<journal-title>Nephrology Dialysis Transplantation</journal-title>
</journal-title-group>
<issn pub-type="ppub">0931-0509</issn>
<issn pub-type="epub">1460-2385</issn>
<publisher>
<publisher-name>Oxford University Press</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmc">7107803</article-id>
<article-id pub-id-type="doi">10.1093/ndt/gfw198.64</article-id>
<article-id pub-id-type="publisher-id">gfw198</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>POSTER SESSION</subject>
<subj-group subj-group-type="category-toc-heading">
<subject>Monday, May 23rd, 2016: Posters (sorted by session)</subject>
<subj-group subj-group-type="category-toc-heading">
<subject>Dialysis. Epidemiology, Outcome Research, Health Services Research - 2</subject>
</subj-group>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>MP647
<break></break>
OUTCOMES OF HEMODIALYSIS PATIENTS WITH MERS-COV EXPOSURE IN KOREA</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Lee</surname>
<given-names>Young-Ki</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Cho</surname>
<given-names>Ajin</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Yoon</surname>
<given-names>Jong-Woo</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Jeon</surname>
<given-names>Hee Jung</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ryu</surname>
<given-names>Ji Won</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Noh</surname>
<given-names>Jung-Woo</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Choi</surname>
<given-names>Yoo Jin</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bae</surname>
<given-names>Eun Ji</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kim</surname>
<given-names>Eun Yi</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Jeong</surname>
<given-names>Da-Wun</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kim</surname>
<given-names>Yang-Gyun</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lee</surname>
<given-names>Sang-Ho</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lee</surname>
<given-names>Chang-Hee</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Yoo</surname>
<given-names>Kyung Don</given-names>
</name>
<xref ref-type="aff" rid="MP647_aff_4">4</xref>
</contrib>
</contrib-group>
<aff id="MP647_aff_1">
<label>1</label>
Hallym University College of Medicine, Internal Medicine, Seoul, REPUBLIC OF KOREA</aff>
<aff id="MP647_aff_2">
<label>2</label>
Kyung Hee University at Kangdong, Nephrology, Seoul, REPUBLIC OF KOREA</aff>
<aff id="MP647_aff_3">
<label>3</label>
Gangeung Medical Center, Anesthesiology, Gangeung, REPUBLIC OF KOREA</aff>
<aff id="MP647_aff_4">
<label>4</label>
Dongguk University Medical Center, Internal Medicine, Gyeongju, REPUBLIC OF KOREA</aff>
<pub-date pub-type="ppub">
<month>5</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub" iso-8601-date="2016-05-14">
<day>14</day>
<month>5</month>
<year>2016</year>
</pub-date>
<volume>31</volume>
<issue>Suppl 1</issue>
<issue-id pub-id-type="doi">10.1093/ndt/gfw109</issue-id>
<issue-title>53rd ERA-EDTA Congress, May 21st-24th, 2016, Vienna, Austria</issue-title>
<fpage>i555</fpage>
<lpage>i556</lpage>
<permissions>
<copyright-statement>© The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.</copyright-statement>
<copyright-year>2016</copyright-year>
<license>
<license-p>This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.</license-p>
</license>
</permissions>
<self-uri xlink:href="gfw198.64.pdf"></self-uri>
</article-meta>
</front>
<body>
<p>
<bold>Introduction and Aims:</bold>
A large outbreak of the Middle East respiratory syndrome corona virus (MERS-CoV) infection occurred in Korea from May until early July 2015. There have been 186 laboratory-confirmed cases with healthcare facilities, including one case with maintenance hemodialysis (HD). Strategies to contain MERS-CoV depend on knowledge of the rate of human-to-human transmission. There has been no targeted study of secondary transmission in HD unit.</p>
<p>
<bold>Methods:</bold>
We studied HD clusters that were incidentally exposed to patients or health care workers with confirmed MERS-CoV infection. Probable cases of secondary transmission were identified on the basis of reactivity in two reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assays with independent RNA extraction from respiratory secretions.</p>
<p>
<bold>Results:</bold>
One hundred twenty-five patients and twenty health care workers were exposed to MERS-CoV in three HD units. In our study population, we did not found secondary transmission of MERS-CoV in HD units in spite of different isolation practices (Table).</p>
<p>
<bold>Conclusions:</bold>
A lot of cases acquired by person-to-person transmission in HD units in other countries, whereas no secondary transmission was occurred in Korea. To determine the best isolation system in HD units, the cost-effectiveness analysis of different strategies and MERS-CoV serological study for asymptomatic infections are needed. </p>
<table-wrap id="MP647_2_BDEF112F-95D3-4D50-830A-69AE2FF7F12F" orientation="portrait" position="anchor">
<caption>
<p>Isolation practices and outcomes in HD units</p>
</caption>
<table frame="hsides" rules="groups">
<colgroup span="1">
<col align="left" span="1"></col>
<col align="left" span="1"></col>
<col align="left" span="1"></col>
<col align="left" span="1"></col>
</colgroup>
<thead>
<tr>
<th colspan="1" rowspan="1"></th>
<th align="left" colspan="1" rowspan="1">Hospital A</th>
<th align="left" colspan="1" rowspan="1">Hospital B</th>
<th align="left" colspan="1" rowspan="1">Hospital C</th>
</tr>
</thead>
<tbody>
<tr>
<td colspan="1" rowspan="1">Maintenance dialysis patients</td>
<td colspan="1" rowspan="1">92</td>
<td colspan="1" rowspan="1">36</td>
<td colspan="1" rowspan="1">135</td>
</tr>
<tr>
<td colspan="1" rowspan="1">MERS-CoV exposure patients</td>
<td colspan="1" rowspan="1">92</td>
<td colspan="1" rowspan="1">25</td>
<td colspan="1" rowspan="1">8</td>
</tr>
<tr>
<td colspan="1" rowspan="1">MERS-CoV exposure health care worker</td>
<td colspan="1" rowspan="1">12</td>
<td colspan="1" rowspan="1">7</td>
<td colspan="1" rowspan="1">1</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Exposure place</td>
<td colspan="1" rowspan="1">HD unit</td>
<td colspan="1" rowspan="1">HD unit</td>
<td colspan="1" rowspan="1">Outside of HD unit</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Exposure source</td>
<td colspan="1" rowspan="1">HD patient</td>
<td colspan="1" rowspan="1">Nurse</td>
<td colspan="1" rowspan="1">ER patient</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Isolation practices</td>
<td colspan="1" rowspan="1">64 patients:
<break></break>
admission & HD in isolation room,
<break></break>
28 patients:
<break></break>
cohort isolation (OPD)</td>
<td colspan="1" rowspan="1">4 patients:
<break></break>
admission & HD in negative pressure isolation room,
<break></break>
21 patients: admission & HD</td>
<td colspan="1" rowspan="1">8 patients: cohort isolation (OPD)</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Secondary transmission</td>
<td colspan="1" rowspan="1">0</td>
<td colspan="1" rowspan="1">0</td>
<td colspan="1" rowspan="1">0</td>
</tr>
</tbody>
</table>
</table-wrap>
</body>
</pmc>
</record>

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