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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">MERS—the latest threat to global health security</title>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26088625</idno>
<idno type="pmc">7138075</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138075</idno>
<idno type="RBID">PMC:7138075</idno>
<idno type="doi">10.1016/S0140-6736(15)61088-1</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000847</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">MERS—the latest threat to global health security</title>
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<series><title level="j">Lancet (London, England)</title>
<idno type="ISSN">0140-6736</idno>
<idno type="eISSN">1474-547X</idno>
<imprint><date when="2015">2015</date>
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<pmc article-type="editorial"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Lancet</journal-id>
<journal-id journal-id-type="iso-abbrev">Lancet</journal-id>
<journal-title-group><journal-title>Lancet (London, England)</journal-title>
</journal-title-group>
<issn pub-type="ppub">0140-6736</issn>
<issn pub-type="epub">1474-547X</issn>
<publisher><publisher-name>Elsevier Ltd.</publisher-name>
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<article-meta><article-id pub-id-type="pmid">26088625</article-id>
<article-id pub-id-type="pmc">7138075</article-id>
<article-id pub-id-type="publisher-id">S0140-6736(15)61088-1</article-id>
<article-id pub-id-type="doi">10.1016/S0140-6736(15)61088-1</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
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<title-group><article-title>MERS—the latest threat to global health security</article-title>
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<contrib-group><contrib contrib-type="author" id="au10"><name><surname>The Lancet</surname>
</name>
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<pub-date pub-type="pmc-release"><day>11</day>
<month>6</month>
<year>2015</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub" iso-8601-date="2015-06-19"><season>13-19 June</season>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub"><day>11</day>
<month>6</month>
<year>2015</year>
</pub-date>
<volume>385</volume>
<issue>9985</issue>
<fpage>2324</fpage>
<lpage>2324</lpage>
<permissions><copyright-statement>Copyright © 2015 Elsevier Ltd. All rights reserved.</copyright-statement>
<copyright-year>2015</copyright-year>
<copyright-holder>Elsevier Ltd</copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
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<related-article related-article-type="commentary-article" id="d32e207" ext-link-type="doi" xlink:href="10.1016/S0140-6736(15)60859-5"></related-article>
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</front>
<body><p id="para10">The spread of Middle East respiratory syndrome (MERS) to South Korea, and now to China, is an important signal of the need for increased vigilance in global health security measures. As reported in Correspondence in this week's issue, the rapid transmission of MERS in South Korea led to 12 laboratory-confirmed cases over a 2-week period in May, and many more cases since, with relatives, medical staff, and a fellow patient all contracting the disease, which started with one 68-year-old man who had travelled to the Middle East. The son of one of these South Korean patients, after visiting his father in hospital, then developed symptoms but nevertheless travelled into mainland China via Hong Kong. He is now in isolation with confirmed MERS in Huizhou, Guangdong province, and high-risk contacts are under surveillance.</p>
<p id="para20">This outbreak of MERS in Seoul is the largest case cluster outside the Middle East. Poor hospital infection control measures are likely to be important in the transmission of MERS here, as with previous outbreaks in Saudi Arabia. Lack of monitoring of close contacts for signs of infection, and prevention of travel to China, are other notable failures. With the exact mode of transmission and source of the MERS coronavirus still unknown, the development of treatments, let alone vaccines, remain a long way off, making prevention all the more important. The spectre of a previous coronavirus infection, which caused severe acute respiratory syndrome (SARS), still hangs over China, contributing to widespread concern and confusion about MERS now.</p>
<p id="para30">With new cases of Ebola still occurring in west Africa, frequent influenza epidemics worldwide, MERS (and previously SARS) adds to the infectious disease threat to global health security. As David Hui and colleagues call for in <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1016/S2213-2600(15)00238-6" id="interrefs10"><italic>The Lancet Respiratory Medicine</italic>
</ext-link>
, we need “bold leadership…to generate the best evidence base for formulating effective public health, infection control and treatment interventions required to effectively tackle these infections”. Our global health security depends upon such leadership.</p>
<p id="para40"><boxed-text id="cetextbox10"><p id="para50">For more on <bold>MERS</bold>
see <bold>Seminar</bold>
<italic>Lancet</italic>
2015; published online June 3. <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1016/S0140-6736(15)60454-8" id="interrefs20">http://dx.doi.org/10.1016/S0140-6736(15)60454-8</ext-link>
</p>
</boxed-text>
</p>
<p id="para60"><fig id="f10"><graphic xlink:href="fx1_lrg"></graphic>
<permissions><copyright-statement>© 2015 Ami Images/Science Photo Library</copyright-statement>
<copyright-year>2015</copyright-year>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
</fig>
</p>
</body>
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