766Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection
Identifieur interne : 000627 ( Pmc/Corpus ); précédent : 000626; suivant : 000628766Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection
Auteurs : Basem Alraddadi ; Noha Bawareth ; Haneen Omar ; Hanadi Alsalmi ; Maun Feteih ; Ghassan WaliSource :
- Open Forum Infectious Diseases [ 2328-8957 ] ; 2014.
Url:
DOI: 10.1093/ofid/ofu052.474
PubMed: NONE
PubMed Central: 5781957
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PMC:5781957Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">766<break></break>Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection</title><author><name sortKey="Alraddadi, Basem" sort="Alraddadi, Basem" uniqKey="Alraddadi B" first="Basem" last="Alraddadi">Basem Alraddadi</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Bawareth, Noha" sort="Bawareth, Noha" uniqKey="Bawareth N" first="Noha" last="Bawareth">Noha Bawareth</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Omar, Haneen" sort="Omar, Haneen" uniqKey="Omar H" first="Haneen" last="Omar">Haneen Omar</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Alsalmi, Hanadi" sort="Alsalmi, Hanadi" uniqKey="Alsalmi H" first="Hanadi" last="Alsalmi">Hanadi Alsalmi</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Feteih, Maun" sort="Feteih, Maun" uniqKey="Feteih M" first="Maun" last="Feteih">Maun Feteih</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Wali, Ghassan" sort="Wali, Ghassan" uniqKey="Wali G" first="Ghassan" last="Wali">Ghassan Wali</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">5781957</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781957</idno><idno type="RBID">PMC:5781957</idno><idno type="doi">10.1093/ofid/ofu052.474</idno><idno type="pmid">NONE</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000627</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000627</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">766<break></break>Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection</title><author><name sortKey="Alraddadi, Basem" sort="Alraddadi, Basem" uniqKey="Alraddadi B" first="Basem" last="Alraddadi">Basem Alraddadi</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Bawareth, Noha" sort="Bawareth, Noha" uniqKey="Bawareth N" first="Noha" last="Bawareth">Noha Bawareth</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Omar, Haneen" sort="Omar, Haneen" uniqKey="Omar H" first="Haneen" last="Omar">Haneen Omar</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Alsalmi, Hanadi" sort="Alsalmi, Hanadi" uniqKey="Alsalmi H" first="Hanadi" last="Alsalmi">Hanadi Alsalmi</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Feteih, Maun" sort="Feteih, Maun" uniqKey="Feteih M" first="Maun" last="Feteih">Maun Feteih</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Wali, Ghassan" sort="Wali, Ghassan" uniqKey="Wali G" first="Ghassan" last="Wali">Ghassan Wali</name><affiliation><nlm:aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</nlm:aff></affiliation></author></analytic><series><title level="j">Open Forum Infectious Diseases</title><idno type="eISSN">2328-8957</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader></TEI><pmc article-type="abstract"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Open Forum Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">Open Forum Infect Dis</journal-id><journal-id journal-id-type="publisher-id">ofid</journal-id><journal-id journal-id-type="hwp">ofids</journal-id><journal-title-group><journal-title>Open Forum Infectious Diseases</journal-title></journal-title-group><issn pub-type="epub">2328-8957</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">5781957</article-id><article-id pub-id-type="doi">10.1093/ofid/ofu052.474</article-id><article-id pub-id-type="publisher-id">ofu052</article-id><article-categories><subj-group subj-group-type="heading"><subject>IDWeek 2014 Abstracts</subject><subj-group subj-group-type="category-toc-heading"><subject>Poster Abstracts</subject></subj-group></subj-group></article-categories><title-group><article-title>766<break></break>Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Alraddadi</surname><given-names>Basem</given-names></name><degrees>MD, MS</degrees><xref ref-type="aff" rid="d28648e79"></xref></contrib><contrib contrib-type="author"><name><surname>Bawareth</surname><given-names>Noha</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="d28648e79"></xref></contrib><contrib contrib-type="author"><name><surname>Omar</surname><given-names>Haneen</given-names></name><xref ref-type="aff" rid="d28648e79"></xref></contrib><contrib contrib-type="author"><name><surname>Alsalmi</surname><given-names>Hanadi</given-names></name><degrees>MS</degrees><xref ref-type="aff" rid="d28648e79"></xref></contrib><contrib contrib-type="author"><name><surname>Feteih</surname><given-names>Maun</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="d28648e79"></xref></contrib><contrib contrib-type="author"><name><surname>Wali</surname><given-names>Ghassan</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="d28648e79"></xref></contrib></contrib-group><aff id="d28648e79">King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia</aff><author-notes><fn id="TN61" fn-type="con"><p><bold>Session:</bold> 106. Clinical Respiratory Infections</p></fn><fn id="TN62" fn-type="con"><p><italic>Friday, October 10, 2014: 12:30 PM</italic></p></fn></author-notes><pub-date pub-type="ppub"><month>12</month><year>2014</year></pub-date><pub-date pub-type="epub" iso-8601-date="2014-12-01"><month>12</month><year>2014</year></pub-date><volume>1</volume><issue>Suppl 1</issue><issue-title>IDWeek 2014 Abstracts</issue-title><fpage>S216</fpage><lpage>S216</lpage><permissions><copyright-statement>© The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America</copyright-statement><copyright-year>2014</copyright-year><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.</license-p></license></permissions><self-uri xlink:href="ofu052.474.pdf"></self-uri></article-meta></front><body><p><bold><italic>Background.</italic></bold> The number of laboratory confirmed cases of Middle East Respiratory Syndrome-Corona Virus is increasing and has been associated with high mortality rate. Our aim is to describe clinical features and outcome of patients infected with MERS CoV in a tertiary hospital outbreak in Jeddah, Saudi Arabia.</p><p><bold><italic>Methods.</italic></bold> We reviewed the medical records of 30 patients with confirmed MERS CoV infections during hospital outbreak between April 7 until April 30, 2014. We followed WHO definitions for confirmed MERS CoV infection.</p><p><bold><italic>Results.</italic></bold> A total of 30 patients were diagnosed with confirmed MERS CoV infection. 16 patients were health care workers. The mean age was 43 years (SD 16.5). Seventeen patients were male (54.8%). Majority of patients N = 20 (66.7%) were symptomatic on presentation. Fever was the most presenting symptoms N = 20 (66.7%) followed by cough N = 18 (60%). Although only 10 patients (35.7%) reported shortness of breath on presentation, 27 patients (93.1%) had abnormal chest xary. In terms of laboratory findings, 13 patients (54.2%) had lymphopenia on presentation. Significant number of patients developed progressive respiratory disease; 9 patients (30%) required mechanical ventilation and 12 patients (38.7%) required ICU admission.</p><p><bold><italic>Conclusion.</italic></bold> Fever and abnormal chest x ray were the most common clinical features in patients with MERS CoV infection. Significant number of MERS CoV patient's required mechanical ventilation and ICU admission.</p><p><bold><italic>Disclosures.</italic></bold> <bold>All authors:</bold> No reported disclosures.</p></body></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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