The persistent prevalence and evolution of cross-family recombinant coronavirus GCCDC1 among a bat population: a two-year follow-up
Identifieur interne : 000423 ( Pmc/Corpus ); précédent : 000422; suivant : 000424The persistent prevalence and evolution of cross-family recombinant coronavirus GCCDC1 among a bat population: a two-year follow-up
Auteurs : Joseph O. Obameso ; Hong Li ; Hao Jia ; Min Han ; Shiyan Zhu ; Canping Huang ; Yuhui Zhao ; Min Zhao ; Yu Bai ; Fei Yuan ; Honglan Zhao ; Xia Peng ; Wen Xu ; Wenjie Tan ; Yingze Zhao ; Kwok-Yung Yuen ; William J. Liu ; Lin Lu ; George F. GaoSource :
- Science China. Life Sciences [ 1674-7305 ] ; 2017.
Abstract
Bats are connected with the increasing numbers of emerging and re-emerging viruses that may break the species barrier and spread into the human population. Coronaviruses are one of the most common viruses discovered in bats, which were considered as the natural source of recent human-susceptible coronaviruses, i.e. SARS-COV and MERS-CoV. Our previous study reported the discovery of a bat-derived putative cross-family recombinant coronavirus with a reovirus gene
Url:
DOI: 10.1007/s11427-017-9263-6
PubMed: 29299855
PubMed Central: 7088801
Links to Exploration step
PMC:7088801Le document en format XML
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Obameso</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff></affiliation></author><author><name sortKey="Li, Hong" sort="Li, Hong" uniqKey="Li H" first="Hong" last="Li">Hong Li</name><affiliation><nlm:aff id="Aff2">Yunnan Provincial Center for Disease Control and Prevention, Kunming, 650022 China</nlm:aff></affiliation></author><author><name sortKey="Jia, Hao" sort="Jia, Hao" uniqKey="Jia H" first="Hao" last="Jia">Hao Jia</name><affiliation><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0348 3990</institution-id><institution-id institution-id-type="GRID">grid.268099.c</institution-id><institution>College of Laboratory Medicine and Life Sciences,</institution><institution>Wenzhou Medical University,</institution></institution-wrap>Wenzhou, 325035 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and 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sort="Peng, Xia" uniqKey="Peng X" first="Xia" last="Peng">Xia Peng</name><affiliation><nlm:aff id="Aff2">Yunnan Provincial Center for Disease Control and Prevention, Kunming, 650022 China</nlm:aff></affiliation></author><author><name sortKey="Xu, Wen" sort="Xu, Wen" uniqKey="Xu W" first="Wen" last="Xu">Wen Xu</name><affiliation><nlm:aff id="Aff2">Yunnan Provincial Center for Disease Control and Prevention, Kunming, 650022 China</nlm:aff></affiliation></author><author><name sortKey="Tan, Wenjie" sort="Tan, Wenjie" uniqKey="Tan W" first="Wenjie" last="Tan">Wenjie Tan</name><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center 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Obameso</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff></affiliation></author><author><name sortKey="Li, Hong" sort="Li, Hong" uniqKey="Li H" first="Hong" last="Li">Hong Li</name><affiliation><nlm:aff id="Aff2">Yunnan Provincial Center for Disease Control and Prevention, Kunming, 650022 China</nlm:aff></affiliation></author><author><name sortKey="Jia, Hao" sort="Jia, Hao" uniqKey="Jia H" first="Hao" last="Jia">Hao Jia</name><affiliation><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0348 3990</institution-id><institution-id institution-id-type="GRID">grid.268099.c</institution-id><institution>College of Laboratory Medicine and Life Sciences,</institution><institution>Wenzhou Medical University,</institution></institution-wrap>Wenzhou, 325035 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author><author><name sortKey="Han, Min" sort="Han, Min" uniqKey="Han M" first="Min" last="Han">Min Han</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff></affiliation></author><author><name sortKey="Zhu, Shiyan" sort="Zhu, Shiyan" uniqKey="Zhu S" first="Shiyan" last="Zhu">Shiyan Zhu</name><affiliation><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0348 3990</institution-id><institution-id institution-id-type="GRID">grid.268099.c</institution-id><institution>College of Laboratory Medicine and Life Sciences,</institution><institution>Wenzhou Medical University,</institution></institution-wrap>Wenzhou, 325035 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author><author><name sortKey="Huang, Canping" sort="Huang, Canping" uniqKey="Huang C" first="Canping" last="Huang">Canping Huang</name><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author><author><name sortKey="Zhao, Yuhui" sort="Zhao, Yuhui" uniqKey="Zhao Y" first="Yuhui" last="Zhao">Yuhui Zhao</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff></affiliation></author><author><name sortKey="Zhao, Min" sort="Zhao, 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institution-id-type="GRID">grid.9227.e</institution-id><institution>CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff></affiliation></author><author><name sortKey="Zhao, Honglan" sort="Zhao, Honglan" uniqKey="Zhao H" first="Honglan" last="Zhao">Honglan Zhao</name><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author><author><name sortKey="Peng, Xia" sort="Peng, Xia" uniqKey="Peng X" first="Xia" last="Peng">Xia Peng</name><affiliation><nlm:aff id="Aff2">Yunnan Provincial Center for Disease Control and Prevention, Kunming, 650022 China</nlm:aff></affiliation></author><author><name sortKey="Xu, Wen" sort="Xu, Wen" uniqKey="Xu W" first="Wen" last="Xu">Wen Xu</name><affiliation><nlm:aff id="Aff2">Yunnan Provincial Center for Disease Control and Prevention, Kunming, 650022 China</nlm:aff></affiliation></author><author><name sortKey="Tan, Wenjie" sort="Tan, Wenjie" uniqKey="Tan W" first="Wenjie" last="Tan">Wenjie Tan</name><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author><author><name sortKey="Zhao, Yingze" sort="Zhao, Yingze" uniqKey="Zhao Y" first="Yingze" last="Zhao">Yingze Zhao</name><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation><nlm:aff id="Aff6"><institution-wrap><institution-id institution-id-type="GRID">grid.194645.b</institution-id><institution-id institution-id-type="ISNI">0000000121742757</institution-id><institution>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong,</institution><institution>Hong Kong Special Administrative Region,</institution></institution-wrap>Hong Kong, China</nlm:aff></affiliation></author><author><name sortKey="Liu, William J" sort="Liu, William J" uniqKey="Liu W" first="William J." last="Liu">William J. Liu</name><affiliation><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0348 3990</institution-id><institution-id institution-id-type="GRID">grid.268099.c</institution-id><institution>College of Laboratory Medicine and Life Sciences,</institution><institution>Wenzhou Medical University,</institution></institution-wrap>Wenzhou, 325035 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author><author><name sortKey="Lu, Lin" sort="Lu, Lin" uniqKey="Lu L" first="Lin" last="Lu">Lin Lu</name><affiliation><nlm:aff id="Aff2">Yunnan Provincial Center for Disease Control and Prevention, Kunming, 650022 China</nlm:aff></affiliation></author><author><name sortKey="Gao, George F" sort="Gao, George F" uniqKey="Gao G" first="George F." last="Gao">George F. Gao</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff></affiliation><affiliation><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</nlm:aff></affiliation></author></analytic><series><title level="j">Science China. Life Sciences</title><idno type="ISSN">1674-7305</idno><idno type="eISSN">1869-1889</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Bats are connected with the increasing numbers of emerging and re-emerging viruses that may break the species barrier and spread into the human population. Coronaviruses are one of the most common viruses discovered in bats, which were considered as the natural source of recent human-susceptible coronaviruses, i.e. SARS-COV and MERS-CoV. Our previous study reported the discovery of a bat-derived putative cross-family recombinant coronavirus with a reovirus gene <italic>p10</italic>, named as Ro-BatCoV GCCDC1. In this report, through a two-year follow-up of a special bat population in one specific cave of south China, we illustrate that Ro-BatCoV GCCDC1 persistently circulates among bats. Notably, through the longitudinal observation, we identified the dynamic evolution of Ro-BatCoV GCCDC1 in bats represented by continuously recombination events. Our study provides the first glimpse of the virus evolution in one longitudinally observed bat population cohort and underlines the surveillance and pre-warning of potential interspecies transmittable viruses in bats.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author><author><name sortKey="Fu, K" uniqKey="Fu K">K. Fu</name></author><author><name sortKey="Chen, W" uniqKey="Chen W">W. Chen</name></author><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Calisher, C H" uniqKey="Calisher C">C.H. Calisher</name></author><author><name sortKey="Childs, J E" uniqKey="Childs J">J.E. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Sci China Life Sci</journal-id><journal-id journal-id-type="iso-abbrev">Sci China Life Sci</journal-id><journal-title-group><journal-title>Science China. Life Sciences</journal-title></journal-title-group><issn pub-type="ppub">1674-7305</issn><issn pub-type="epub">1869-1889</issn><publisher><publisher-name>Science China Press</publisher-name><publisher-loc>Beijing</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">29299855</article-id><article-id pub-id-type="pmc">7088801</article-id><article-id pub-id-type="publisher-id">9263</article-id><article-id pub-id-type="doi">10.1007/s11427-017-9263-6</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Paper</subject></subj-group></article-categories><title-group><article-title>The persistent prevalence and evolution of cross-family recombinant coronavirus GCCDC1 among a bat population: a two-year follow-up</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name><surname>Obameso</surname><given-names>Joseph O.</given-names></name><xref ref-type="aff" rid="Aff1">1</xref><xref 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Sciences,</institution></institution-wrap>Beijing, 100049 China</aff><aff id="Aff4"><label>4</label><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0348 3990</institution-id><institution-id institution-id-type="GRID">grid.268099.c</institution-id><institution>College of Laboratory Medicine and Life Sciences,</institution><institution>Wenzhou Medical University,</institution></institution-wrap>Wenzhou, 325035 China</aff><aff id="Aff5"><label>5</label><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8803 2373</institution-id><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution>Key Laboratory of Medical Virology and Viral Diseases, Ministry of Health of People’s Republic of China, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</aff><aff id="Aff6"><label>6</label><institution-wrap><institution-id institution-id-type="GRID">grid.194645.b</institution-id><institution-id institution-id-type="ISNI">0000000121742757</institution-id><institution>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong,</institution><institution>Hong Kong Special Administrative Region,</institution></institution-wrap>Hong Kong, China</aff></contrib-group><pub-date pub-type="epub"><day>1</day><month>12</month><year>2017</year></pub-date><pub-date pub-type="ppub"><year>2017</year></pub-date><volume>60</volume><issue>12</issue><fpage>1357</fpage><lpage>1363</lpage><history><date date-type="received"><day>11</day><month>9</month><year>2017</year></date><date date-type="accepted"><day>23</day><month>10</month><year>2017</year></date></history><permissions><copyright-statement>© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2017</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><p>Bats are connected with the increasing numbers of emerging and re-emerging viruses that may break the species barrier and spread into the human population. Coronaviruses are one of the most common viruses discovered in bats, which were considered as the natural source of recent human-susceptible coronaviruses, i.e. SARS-COV and MERS-CoV. Our previous study reported the discovery of a bat-derived putative cross-family recombinant coronavirus with a reovirus gene <italic>p10</italic>, named as Ro-BatCoV GCCDC1. In this report, through a two-year follow-up of a special bat population in one specific cave of south China, we illustrate that Ro-BatCoV GCCDC1 persistently circulates among bats. Notably, through the longitudinal observation, we identified the dynamic evolution of Ro-BatCoV GCCDC1 in bats represented by continuously recombination events. Our study provides the first glimpse of the virus evolution in one longitudinally observed bat population cohort and underlines the surveillance and pre-warning of potential interspecies transmittable viruses in bats.</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>coronavirus</kwd><kwd>bat population</kwd><kwd>evolution</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2017</meta-value></custom-meta></custom-meta-group></article-meta></front><back><fn-group><fn><p>Contributed equally to this work</p></fn></fn-group><ack><title>Acknowledgements</title><p>We appreciate the great efforts of Drs. Yongming Zhou, Honghua Wen, Huaxing Liu, who participated in the collection of the bat samples. This work was supported by the National Key Research and Development Program of China (2017YFC1200202), the National Natural Science Foundation of China (81290342, 81461168030), the Major Special Projects for Infectious Disease Research of China (2016ZX10004222-003), and China National Grand S&T Special Project (2014ZX10004-001-006). Joseph O. Obameso was supported by CAS-TWAS President’s Fellowship of the University of Chinese Academy of Sciences (UCAS) and The World Academy of Sciences (TWAS). George F. Gao is a leading principle investigator of the NSFC Innovative Research Group (81621091). 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