Serveur d'exploration MERS

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A numerical study of ventilation strategies for infection risk mitigation in general inpatient wards

Identifieur interne : 000344 ( Pmc/Corpus ); précédent : 000343; suivant : 000345

A numerical study of ventilation strategies for infection risk mitigation in general inpatient wards

Auteurs : Manoj Kumar Satheesan ; Kwok Wai Mui ; Ling Tim Wong

Source :

RBID : PMC:7090571

Abstract

Aerial dispersion of human exhaled microbial contaminants and subsequent contamination of surfaces is a potential route for infection transmission in hospitals. Most general hospital wards have ventilation systems that drive air and thus contaminants from the patient areas towards the corridors. This study investigates the transport mechanism and deposition patterns of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) within a typical six bedded general inpatient ward cubicle through numerical simulation. It demonstrates that both air change and exhaust airflow rates have significant effects on not only the airflow but also the particle distribution within a mechanically ventilated space. Moreover, the location of an infected patient within the ward cubicle is crucial in determining the extent of infection risk to other ward occupants. Hence, it is recommended to provide exhaust grilles in close proximity to a patient, preferably above each patient’s bed. To achieve infection prevention and control, high exhaust airflow rate is also suggested. Regardless of the ventilation design, all patients and any surfaces within a ward cubicle should be regularly and thoroughly cleaned and disinfected to remove microbial contamination. The outcome of this study can serve as a source of reference for hospital management to better ventilation design strategies for mitigating the risk of infection.


Url:
DOI: 10.1007/s12273-020-0623-4
PubMed: 32211123
PubMed Central: 7090571

Links to Exploration step

PMC:7090571

Le document en format XML

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<p>Aerial dispersion of human exhaled microbial contaminants and subsequent contamination of surfaces is a potential route for infection transmission in hospitals. Most general hospital wards have ventilation systems that drive air and thus contaminants from the patient areas towards the corridors. This study investigates the transport mechanism and deposition patterns of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) within a typical six bedded general inpatient ward cubicle through numerical simulation. It demonstrates that both air change and exhaust airflow rates have significant effects on not only the airflow but also the particle distribution within a mechanically ventilated space. Moreover, the location of an infected patient within the ward cubicle is crucial in determining the extent of infection risk to other ward occupants. Hence, it is recommended to provide exhaust grilles in close proximity to a patient, preferably above each patient’s bed. To achieve infection prevention and control, high exhaust airflow rate is also suggested. Regardless of the ventilation design, all patients and any surfaces within a ward cubicle should be regularly and thoroughly cleaned and disinfected to remove microbial contamination. The outcome of this study can serve as a source of reference for hospital management to better ventilation design strategies for mitigating the risk of infection.</p>
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<journal-id journal-id-type="nlm-ta">Build Simul</journal-id>
<journal-id journal-id-type="iso-abbrev">Build Simul</journal-id>
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<journal-title>Building Simulation</journal-title>
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<issn pub-type="ppub">1996-3599</issn>
<issn pub-type="epub">1996-8744</issn>
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<publisher-name>Tsinghua University Press</publisher-name>
<publisher-loc>Beijing</publisher-loc>
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<article-meta>
<article-id pub-id-type="pmid">32211123</article-id>
<article-id pub-id-type="pmc">7090571</article-id>
<article-id pub-id-type="publisher-id">623</article-id>
<article-id pub-id-type="doi">10.1007/s12273-020-0623-4</article-id>
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<subject>Research Article</subject>
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<title-group>
<article-title>A numerical study of ventilation strategies for infection risk mitigation in general inpatient wards</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Satheesan</surname>
<given-names>Manoj Kumar</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mui</surname>
<given-names>Kwok Wai</given-names>
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<contrib contrib-type="author" corresp="yes">
<name>
<surname>Wong</surname>
<given-names>Ling Tim</given-names>
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<address>
<email>beltw@polyu.edu.hk</email>
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<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<aff id="Aff1">
<institution-wrap>
<institution-id institution-id-type="GRID">grid.16890.36</institution-id>
<institution-id institution-id-type="ISNI">0000 0004 1764 6123</institution-id>
<institution>Department of Building Services Engineering,</institution>
<institution>The Hong Kong Polytechnic University,</institution>
</institution-wrap>
Hong Kong, China</aff>
</contrib-group>
<pub-date pub-type="epub">
<day>22</day>
<month>2</month>
<year>2020</year>
</pub-date>
<fpage>1</fpage>
<lpage>10</lpage>
<history>
<date date-type="received">
<day>26</day>
<month>11</month>
<year>2019</year>
</date>
<date date-type="rev-recd">
<day>16</day>
<month>1</month>
<year>2020</year>
</date>
<date date-type="accepted">
<day>15</day>
<month>2</month>
<year>2020</year>
</date>
</history>
<permissions>
<copyright-statement>© Tsinghua University Press and Springer-Verlag GmbH Germany, part of Springer Nature 2020</copyright-statement>
<license>
<license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p>
</license>
</permissions>
<abstract id="Abs1">
<p>Aerial dispersion of human exhaled microbial contaminants and subsequent contamination of surfaces is a potential route for infection transmission in hospitals. Most general hospital wards have ventilation systems that drive air and thus contaminants from the patient areas towards the corridors. This study investigates the transport mechanism and deposition patterns of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) within a typical six bedded general inpatient ward cubicle through numerical simulation. It demonstrates that both air change and exhaust airflow rates have significant effects on not only the airflow but also the particle distribution within a mechanically ventilated space. Moreover, the location of an infected patient within the ward cubicle is crucial in determining the extent of infection risk to other ward occupants. Hence, it is recommended to provide exhaust grilles in close proximity to a patient, preferably above each patient’s bed. To achieve infection prevention and control, high exhaust airflow rate is also suggested. Regardless of the ventilation design, all patients and any surfaces within a ward cubicle should be regularly and thoroughly cleaned and disinfected to remove microbial contamination. The outcome of this study can serve as a source of reference for hospital management to better ventilation design strategies for mitigating the risk of infection.</p>
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<kwd-group xml:lang="en">
<title>Keywords</title>
<kwd>ventilation</kwd>
<kwd>bioaerosol dispersion</kwd>
<kwd>indoor air quality (IAQ)</kwd>
<kwd>infection risk</kwd>
<kwd>hospital general ward</kwd>
<kwd>computational fluid dynamics (CFD)</kwd>
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</article-meta>
</front>
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<ack>
<title>Acknowledgements</title>
<p>This work was partially supported by the Research Grants Council of HKSAR and The Hong Kong Polytechnic University (Project No. 15208817E).</p>
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<article-title>Middle East respiratory syndrome</article-title>
<source>The Lancet</source>
<year>2015</year>
<volume>386</volume>
<fpage>995</fpage>
<lpage>1007</lpage>
<pub-id pub-id-type="doi">10.1016/S0140-6736(15)60454-8</pub-id>
</element-citation>
</ref>
</ref-list>
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