MersV1, Pmc, Checkpoint, bibRecord, 001214

Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

Identifieur interne : 001214 ( Pmc/Checkpoint ); précédent : 001213; suivant : 001215

Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

Auteurs : Stefanie Gierer ; Heike Hofmann-Winkler ; Waleed H. Albuali ; Stephanie Bertram ; Abdullah M. Al-Rubaish ; Abdullah A. Yousef ; Awatif N. Al-Nafaie ; Amein K. Al-Ali ; Obeid E. Obeid ; Khaled R. Alkharsah ; Stefan Pöhlmann

Source :

Emerging Infectious Diseases [ 1080-6040 ] ; 2013.

RBID : PMC:3840893

Abstract

We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840893

DOI: 10.3201/eid1912.130701
PubMed: 24274664
PubMed Central: 3840893

Affiliations:

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PMC:3840893

Le document en format XML

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<author><name sortKey="Gierer, Stefanie" sort="Gierer, Stefanie" uniqKey="Gierer S" first="Stefanie" last="Gierer">Stefanie Gierer</name>
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<author><name sortKey="Hofmann Winkler, Heike" sort="Hofmann Winkler, Heike" uniqKey="Hofmann Winkler H" first="Heike" last="Hofmann-Winkler">Heike Hofmann-Winkler</name>
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<author><name sortKey="Albuali, Waleed H" sort="Albuali, Waleed H" uniqKey="Albuali W" first="Waleed H." last="Albuali">Waleed H. Albuali</name>
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<author><name sortKey="Bertram, Stephanie" sort="Bertram, Stephanie" uniqKey="Bertram S" first="Stephanie" last="Bertram">Stephanie Bertram</name>
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<author><name sortKey="Al Rubaish, Abdullah M" sort="Al Rubaish, Abdullah M" uniqKey="Al Rubaish A" first="Abdullah M." last="Al-Rubaish">Abdullah M. Al-Rubaish</name>
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<author><name sortKey="Yousef, Abdullah A" sort="Yousef, Abdullah A" uniqKey="Yousef A" first="Abdullah A." last="Yousef">Abdullah A. Yousef</name>
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<author><name sortKey="Al Nafaie, Awatif N" sort="Al Nafaie, Awatif N" uniqKey="Al Nafaie A" first="Awatif N." last="Al-Nafaie">Awatif N. Al-Nafaie</name>
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<author><name sortKey="Al Ali, Amein K" sort="Al Ali, Amein K" uniqKey="Al Ali A" first="Amein K." last="Al-Ali">Amein K. Al-Ali</name>
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<author><name sortKey="Obeid, Obeid E" sort="Obeid, Obeid E" uniqKey="Obeid O" first="Obeid E." last="Obeid">Obeid E. Obeid</name>
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<author><name sortKey="Alkharsah, Khaled R" sort="Alkharsah, Khaled R" uniqKey="Alkharsah K" first="Khaled R." last="Alkharsah">Khaled R. Alkharsah</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia</title>
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<author><name sortKey="Albuali, Waleed H" sort="Albuali, Waleed H" uniqKey="Albuali W" first="Waleed H." last="Albuali">Waleed H. Albuali</name>
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<author><name sortKey="Bertram, Stephanie" sort="Bertram, Stephanie" uniqKey="Bertram S" first="Stephanie" last="Bertram">Stephanie Bertram</name>
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<author><name sortKey="Al Rubaish, Abdullah M" sort="Al Rubaish, Abdullah M" uniqKey="Al Rubaish A" first="Abdullah M." last="Al-Rubaish">Abdullah M. Al-Rubaish</name>
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<author><name sortKey="Yousef, Abdullah A" sort="Yousef, Abdullah A" uniqKey="Yousef A" first="Abdullah A." last="Yousef">Abdullah A. Yousef</name>
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<author><name sortKey="Al Nafaie, Awatif N" sort="Al Nafaie, Awatif N" uniqKey="Al Nafaie A" first="Awatif N." last="Al-Nafaie">Awatif N. Al-Nafaie</name>
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<author><name sortKey="Al Ali, Amein K" sort="Al Ali, Amein K" uniqKey="Al Ali A" first="Amein K." last="Al-Ali">Amein K. Al-Ali</name>
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<author><name sortKey="Obeid, Obeid E" sort="Obeid, Obeid E" uniqKey="Obeid O" first="Obeid E." last="Obeid">Obeid E. Obeid</name>
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<author><name sortKey="Alkharsah, Khaled R" sort="Alkharsah, Khaled R" uniqKey="Alkharsah K" first="Khaled R." last="Alkharsah">Khaled R. Alkharsah</name>
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<series><title level="j">Emerging Infectious Diseases</title>
<idno type="ISSN">1080-6040</idno>
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<front><div type="abstract" xml:lang="en"><p>We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.</p>
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  <front><journal-meta><journal-id journal-id-type="nlm-ta">Emerg Infect Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Emerging Infect. Dis</journal-id>
<journal-id journal-id-type="publisher-id">EID</journal-id>
<journal-title-group><journal-title>Emerging Infectious Diseases</journal-title>
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<issn pub-type="ppub">1080-6040</issn>
<issn pub-type="epub">1080-6059</issn>
<publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name>
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<article-meta><article-id pub-id-type="pmid">24274664</article-id>
<article-id pub-id-type="pmc">3840893</article-id>
<article-id pub-id-type="publisher-id">13-0701</article-id>
<article-id pub-id-type="doi">10.3201/eid1912.130701</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Dispatch</subject>
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<subj-group subj-group-type="article-type"><subject>Dispatch</subject>
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<title-group><article-title>Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia</article-title>
<alt-title alt-title-type="running-head">MERS Coronavirus, Eastern Province, Saudi Arabia</alt-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Gierer</surname>
<given-names>Stefanie</given-names>
</name>
<xref ref-type="fn" rid="FN1"><sup>1</sup>
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<contrib contrib-type="author"><name><surname>Hofmann-Winkler</surname>
<given-names>Heike</given-names>
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<xref ref-type="fn" rid="FN1"><sup>1</sup>
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<contrib contrib-type="author"><name><surname>Albuali</surname>
<given-names>Waleed H.</given-names>
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<contrib contrib-type="author"><name><surname>Bertram</surname>
<given-names>Stephanie</given-names>
</name>
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<contrib contrib-type="author"><name><surname>Al-Rubaish</surname>
<given-names>Abdullah M.</given-names>
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<contrib contrib-type="author"><name><surname>Yousef</surname>
<given-names>Abdullah A.</given-names>
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<contrib contrib-type="author"><name><surname>Al-Nafaie</surname>
<given-names>Awatif N.</given-names>
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<contrib contrib-type="author"><name><surname>Al-Ali</surname>
<given-names>Amein K.</given-names>
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<contrib contrib-type="author"><name><surname>Obeid</surname>
<given-names>Obeid E.</given-names>
</name>
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<contrib contrib-type="author"><name><surname>Alkharsah</surname>
<given-names>Khaled R.</given-names>
</name>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Pöhlmann</surname>
<given-names>Stefan</given-names>
</name>
<xref ref-type="fn" rid="FN1"><sup>1</sup>
</xref>
</contrib>
<aff id="aff1">German Primate Center, Göttingen, Germany (S. Gierer, H. Hofmann-Winkler, S. Bertram, S. Pöhlmann);</aff>
<aff id="aff2">University of Dammam, Dammam, Saudi Arabia (W.H. Albuali, A.M. Al-Rubaish, A.A. Yousef, A.N. Al-Nafaie, A.K. Al-Ali, O.E. Obeid, K.R. Alkharsah).</aff>
</contrib-group>
<author-notes><corresp id="cor1">Address for correspondence: Stefan Pöhlmann, Infection Biology Unit, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany; email: <email xlink:href="spoehlmann@dpz.eu">spoehlmann@dpz.eu</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>12</month>
<year>2013</year>
</pub-date>
<volume>19</volume>
<issue>12</issue>
<fpage>2034</fpage>
<lpage>2036</lpage>
<abstract><p>We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.</p>
</abstract>
<kwd-group kwd-group-type="author"><title>Keywords: </title>
<kwd>MERS coronavirus</kwd>
<kwd>neutralizing antibodies</kwd>
<kwd>Saudi Arabia</kwd>
<kwd>spike</kwd>
<kwd>pseudotyping</kwd>
<kwd>MERS-CoV</kwd>
<kwd>viruses</kwd>
<kwd>coronavirus</kwd>
<kwd>Middle East respiratory syndrome coronavirus</kwd>
<kwd>seroprevalence</kwd>
<kwd>serum</kwd>
<kwd>plasma</kwd>
<kwd>respiratory infections</kwd>
</kwd-group>
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</front>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Al Ali, Amein K" sort="Al Ali, Amein K" uniqKey="Al Ali A" first="Amein K." last="Al-Ali">Amein K. Al-Ali</name>
<name sortKey="Al Nafaie, Awatif N" sort="Al Nafaie, Awatif N" uniqKey="Al Nafaie A" first="Awatif N." last="Al-Nafaie">Awatif N. Al-Nafaie</name>
<name sortKey="Al Rubaish, Abdullah M" sort="Al Rubaish, Abdullah M" uniqKey="Al Rubaish A" first="Abdullah M." last="Al-Rubaish">Abdullah M. Al-Rubaish</name>
<name sortKey="Albuali, Waleed H" sort="Albuali, Waleed H" uniqKey="Albuali W" first="Waleed H." last="Albuali">Waleed H. Albuali</name>
<name sortKey="Alkharsah, Khaled R" sort="Alkharsah, Khaled R" uniqKey="Alkharsah K" first="Khaled R." last="Alkharsah">Khaled R. Alkharsah</name>
<name sortKey="Bertram, Stephanie" sort="Bertram, Stephanie" uniqKey="Bertram S" first="Stephanie" last="Bertram">Stephanie Bertram</name>
<name sortKey="Gierer, Stefanie" sort="Gierer, Stefanie" uniqKey="Gierer S" first="Stefanie" last="Gierer">Stefanie Gierer</name>
<name sortKey="Hofmann Winkler, Heike" sort="Hofmann Winkler, Heike" uniqKey="Hofmann Winkler H" first="Heike" last="Hofmann-Winkler">Heike Hofmann-Winkler</name>
<name sortKey="Obeid, Obeid E" sort="Obeid, Obeid E" uniqKey="Obeid O" first="Obeid E." last="Obeid">Obeid E. Obeid</name>
<name sortKey="Pohlmann, Stefan" sort="Pohlmann, Stefan" uniqKey="Pohlmann S" first="Stefan" last="Pöhlmann">Stefan Pöhlmann</name>
<name sortKey="Yousef, Abdullah A" sort="Yousef, Abdullah A" uniqKey="Yousef A" first="Abdullah A." last="Yousef">Abdullah A. Yousef</name>
</noCountry>
</tree>
</affiliations>
</record>

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Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

Source :

Abstract

Links toward previous steps (curation, corpus...)

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Le document en format XML

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Pour générer des pages wiki