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MERS Coronaviruses in Dromedary Camels, Egypt

Identifieur interne : 001041 ( Pmc/Checkpoint ); précédent : 001040; suivant : 001042

MERS Coronaviruses in Dromedary Camels, Egypt

Auteurs : Daniel K. W. Chu ; Leo L. M. Poon ; Mokhtar M. Gomaa ; Mahmoud M. Shehata ; Ranawaka A. P. M. Perera ; Dina Abu Zeid ; Amira S. El Rifay ; Lewis Y. Siu ; Yi Guan ; Richard J. Webby ; Mohamed A. Ali ; Malik Peiris ; Ghazi Kayali

Source :

RBID : PMC:4036765

Abstract

We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are infecting dromedaries beyond the Arabian Peninsula, where human MERS-CoV infections have not yet been detected.


Url:
DOI: 10.3201/eid2006.140299
PubMed: 24856660
PubMed Central: 4036765


Affiliations:


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PMC:4036765

Le document en format XML

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<name sortKey="Webby, Richard J" sort="Webby, Richard J" uniqKey="Webby R" first="Richard J." last="Webby">Richard J. Webby</name>
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<name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name>
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<name sortKey="Ali, Mohamed A" sort="Ali, Mohamed A" uniqKey="Ali M" first="Mohamed A." last="Ali">Mohamed A. Ali</name>
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<p>We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are infecting dromedaries beyond the Arabian Peninsula, where human MERS-CoV infections have not yet been detected.</p>
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<journal-id journal-id-type="nlm-ta">Emerg Infect Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Emerging Infect. Dis</journal-id>
<journal-id journal-id-type="publisher-id">EID</journal-id>
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<journal-title>Emerging Infectious Diseases</journal-title>
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<issn pub-type="ppub">1080-6040</issn>
<issn pub-type="epub">1080-6059</issn>
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<publisher-name>Centers for Disease Control and Prevention</publisher-name>
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<article-id pub-id-type="pmid">24856660</article-id>
<article-id pub-id-type="pmc">4036765</article-id>
<article-id pub-id-type="publisher-id">14-0299</article-id>
<article-id pub-id-type="doi">10.3201/eid2006.140299</article-id>
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<subject>Expedited</subject>
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<subject>Dispatch</subject>
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<title-group>
<article-title>MERS Coronaviruses in Dromedary Camels, Egypt</article-title>
<alt-title alt-title-type="running-head">MERS-CoV in Camels, Egypt</alt-title>
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<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Chu</surname>
<given-names>Daniel K.W.</given-names>
</name>
<xref ref-type="fn" rid="FN1">
<sup>1</sup>
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<contrib contrib-type="author">
<name>
<surname>Poon</surname>
<given-names>Leo L.M.</given-names>
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<xref ref-type="fn" rid="FN1">
<sup>1</sup>
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<contrib contrib-type="author">
<name>
<surname>Gomaa</surname>
<given-names>Mokhtar M.</given-names>
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<contrib contrib-type="author">
<name>
<surname>Shehata</surname>
<given-names>Mahmoud M.</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Perera</surname>
<given-names>Ranawaka A.P.M.</given-names>
</name>
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<contrib contrib-type="author">
<name>
<surname>Abu Zeid</surname>
<given-names>Dina</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>El Rifay</surname>
<given-names>Amira S.</given-names>
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<contrib contrib-type="author">
<name>
<surname>Siu</surname>
<given-names>Lewis Y.</given-names>
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<surname>Guan</surname>
<given-names>Yi</given-names>
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<contrib contrib-type="author">
<name>
<surname>Webby</surname>
<given-names>Richard J.</given-names>
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<contrib contrib-type="author">
<name>
<surname>Ali</surname>
<given-names>Mohamed A.</given-names>
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<name>
<surname>Peiris</surname>
<given-names>Malik</given-names>
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<contrib contrib-type="author" corresp="yes">
<name>
<surname>Kayali</surname>
<given-names>Ghazi</given-names>
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<aff id="aff1">The University of Hong Kong, Hong Kong, China (D.K.W. Chu, L.L.M. Poon, R.A.P.M. Perera, Y. Guan, M. Peiris);</aff>
<aff id="aff2">National Research Centre, Giza, Egypt (M.M. Gomaa, M.M. Shehata, D.A. Zeid, A.S. El Rifay, M.A. Ali);</aff>
<aff id="aff3">HKU-Pasteur Research Pole, Hong Kong (L.Y. Siu);</aff>
<aff id="aff4">St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (R.J. Webby, G. Kayali)</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">Addresses for correspondence: Malik Peiris, School of Public Health, The University of Hong Kong, 21 Sassoon Rd, Pokfulam, Hong Kong Special Administrative Region, China; email:
<email xlink:href="malik@hku.hk">malik@hku.hk</email>
; Ghazi Kayali, Division of Virology, Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, TN, USA; email:
<email xlink:href="ghazi.kayali@stjude.org">ghazi.kayali@stjude.org</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>6</month>
<year>2014</year>
</pub-date>
<volume>20</volume>
<issue>6</issue>
<fpage>1049</fpage>
<lpage>1053</lpage>
<abstract>
<p>We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are infecting dromedaries beyond the Arabian Peninsula, where human MERS-CoV infections have not yet been detected.</p>
</abstract>
<kwd-group kwd-group-type="author">
<title>Keywords: </title>
<kwd>zoonosis</kwd>
<kwd>pneumonia</kwd>
<kwd>genomics</kwd>
<kwd>phylogeny</kwd>
<kwd>dromedary</kwd>
<kwd>camel</kwd>
<kwd>Egypt</kwd>
<kwd>viruses</kwd>
<kwd>coronaviruses</kwd>
<kwd>Middle East respiratory syndrome</kwd>
<kwd>MERS</kwd>
<kwd>MERS-CoV</kwd>
</kwd-group>
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<name sortKey="Chu, Daniel K W" sort="Chu, Daniel K W" uniqKey="Chu D" first="Daniel K. W." last="Chu">Daniel K. W. Chu</name>
<name sortKey="El Rifay, Amira S" sort="El Rifay, Amira S" uniqKey="El Rifay A" first="Amira S." last="El Rifay">Amira S. El Rifay</name>
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<name sortKey="Perera, Ranawaka A P M" sort="Perera, Ranawaka A P M" uniqKey="Perera R" first="Ranawaka A. P. M." last="Perera">Ranawaka A. P. M. Perera</name>
<name sortKey="Poon, Leo L M" sort="Poon, Leo L M" uniqKey="Poon L" first="Leo L. M." last="Poon">Leo L. M. Poon</name>
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