MERS: Progress on the global response, remaining challenges and the way forward
Identifieur interne : 000538 ( Pmc/Checkpoint ); précédent : 000537; suivant : 000539MERS: Progress on the global response, remaining challenges and the way forward
Auteurs :Source :
- Antiviral Research [ 0166-3542 ] ; 2018.
Abstract
This article summarizes progress in research on Middle East Respiratory Syndrome (MERS) since a FAO-OIE-WHO Global Technical Meeting held at WHO Headquarters in Geneva on 25–27 September 2017. The meeting reviewed the latest scientific findings and identified and prioritized the global activities necessary to prevent, manage and control the disease. Critical needs for research and technical guidance identified during the meeting have been used to update the WHO R&D MERS-CoV Roadmap for diagnostics, therapeutics and vaccines and a broader public health research agenda. Since the 2017 meeting, progress has been made on several key actions in animal populations, at the animal/human interface and in human populations. This report also summarizes the latest scientific studies on MERS since 2017, including data from more than 50 research studies examining the presence of MERS-CoV infection in dromedary camels.
Url:
DOI: 10.1016/j.antiviral.2018.09.002
PubMed: 30236531
PubMed Central: 7113883
Affiliations:
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PMC:7113883Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>This article summarizes progress in research on Middle East Respiratory Syndrome (MERS) since a FAO-OIE-WHO Global Technical Meeting held at WHO Headquarters in Geneva on 25–27 September 2017. The meeting reviewed the latest scientific findings and identified and prioritized the global activities necessary to prevent, manage and control the disease. Critical needs for research and technical guidance identified during the meeting have been used to update the WHO R&D MERS-CoV Roadmap for diagnostics, therapeutics and vaccines and a broader public health research agenda. Since the 2017 meeting, progress has been made on several key actions in animal populations, at the animal/human interface and in human populations. This report also summarizes the latest scientific studies on MERS since 2017, including data from more than 50 research studies examining the presence of MERS-CoV infection in dromedary camels.</p>
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<pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Antiviral Res</journal-id>
<journal-id journal-id-type="iso-abbrev">Antiviral Res</journal-id>
<journal-title-group><journal-title>Antiviral Research</journal-title>
</journal-title-group>
<issn pub-type="ppub">0166-3542</issn>
<issn pub-type="epub">1872-9096</issn>
<publisher><publisher-name>The Author. Published by Elsevier B.V.</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">30236531</article-id>
<article-id pub-id-type="pmc">7113883</article-id>
<article-id pub-id-type="publisher-id">S0166-3542(18)30530-8</article-id>
<article-id pub-id-type="doi">10.1016/j.antiviral.2018.09.002</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>MERS: Progress on the global response, remaining challenges and the way forward</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><collab>FAO-OIE-WHO MERS Technical Working Group<contrib-group><contrib contrib-type="author" id="au1"><name><surname>Aguanno</surname>
<given-names>Ryan</given-names>
</name>
<xref rid="aff1" ref-type="aff">a</xref>
</contrib>
<contrib contrib-type="author" id="au2"><name><surname>ElIdrissi</surname>
<given-names>Ahmed</given-names>
</name>
<xref rid="aff1" ref-type="aff">a</xref>
</contrib>
<contrib contrib-type="author" id="au3"><name><surname>Elkholy</surname>
<given-names>Amgad A.</given-names>
</name>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author" id="au4"><name><surname>Ben Embarek</surname>
<given-names>Peter</given-names>
</name>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author" id="au5"><name><surname>Gardner</surname>
<given-names>Emma</given-names>
</name>
<xref rid="aff1" ref-type="aff">a</xref>
</contrib>
<contrib contrib-type="author" id="au6"><name><surname>Grant</surname>
<given-names>Rebecca</given-names>
</name>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au7"><name><surname>Mahrous</surname>
<given-names>Heba</given-names>
</name>
<xref rid="aff1" ref-type="aff">a</xref>
</contrib>
<contrib contrib-type="author" id="au8"><name><surname>Malik</surname>
<given-names>Mamunur Rahman</given-names>
</name>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author" id="au9"><name><surname>Pavade</surname>
<given-names>Gounalan</given-names>
</name>
<xref rid="aff4" ref-type="aff">d</xref>
</contrib>
<contrib contrib-type="author" id="au10"><name><surname>VonDobschuetz</surname>
<given-names>Sophie</given-names>
</name>
<xref rid="aff1" ref-type="aff">a</xref>
</contrib>
<contrib contrib-type="author" id="au11"><name><surname>Wiersma</surname>
<given-names>Lidewij</given-names>
</name>
<xref rid="aff1" ref-type="aff">a</xref>
</contrib>
<contrib contrib-type="author" id="au12"><name><surname>Van Kerkhove</surname>
<given-names>Maria D.</given-names>
</name>
<email>vankerkhovem@who.int</email>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
</contrib-group>
<aff id="aff1"><label>a</label>
Food and Agriculture Organization of the United Nations, Italy</aff>
<aff id="aff2"><label>b</label>
Health Emergencies Programme, World Health Organization, Switzerland</aff>
<aff id="aff3"><label>c</label>
Center for Global Health, Institut Pasteur, France</aff>
<aff id="aff4"><label>d</label>
World Organization for Animal Health, France</aff>
</collab>
<xref rid="cor1" ref-type="corresp">∗</xref>
</contrib>
</contrib-group>
<author-notes><corresp id="cor1"><label>∗</label>
Corresponding author. MERS-CoV Technical Lead, High Threat Pathogens, Global Infectious Hazards Management, Health Emergencies Program, World Health Organization, Geneva Switzerland.</corresp>
</author-notes>
<pub-date pub-type="pmc-release"><day>17</day>
<month>9</month>
<year>2018</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>11</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub"><day>17</day>
<month>9</month>
<year>2018</year>
</pub-date>
<volume>159</volume>
<fpage>35</fpage>
<lpage>44</lpage>
<history><date date-type="received"><day>30</day>
<month>8</month>
<year>2018</year>
</date>
<date date-type="accepted"><day>4</day>
<month>9</month>
<year>2018</year>
</date>
</history>
<permissions><copyright-statement>© 2018 The Author. Published by Elsevier B.V.</copyright-statement>
<copyright-year>2018</copyright-year>
<copyright-holder></copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract id="abs0010"><p>This article summarizes progress in research on Middle East Respiratory Syndrome (MERS) since a FAO-OIE-WHO Global Technical Meeting held at WHO Headquarters in Geneva on 25–27 September 2017. The meeting reviewed the latest scientific findings and identified and prioritized the global activities necessary to prevent, manage and control the disease. Critical needs for research and technical guidance identified during the meeting have been used to update the WHO R&D MERS-CoV Roadmap for diagnostics, therapeutics and vaccines and a broader public health research agenda. Since the 2017 meeting, progress has been made on several key actions in animal populations, at the animal/human interface and in human populations. This report also summarizes the latest scientific studies on MERS since 2017, including data from more than 50 research studies examining the presence of MERS-CoV infection in dromedary camels.</p>
</abstract>
<abstract abstract-type="author-highlights" id="abs0015"><title>Highlights</title>
<p><list list-type="simple" id="ulist0010"><list-item id="u0010"><label>•</label>
<p id="p0010">A global technical meeting on MERS was held in Geneva in September, 2017, organized by WHO, FAO and OIE.</p>
</list-item>
<list-item id="u0015"><label>•</label>
<p id="p0015">This report summarizes the latest scientific literature and progress in research on MERS since that meeting.</p>
</list-item>
<list-item id="u0020"><label>•</label>
<p id="p0020">It includes a summary of more than 50 field studies examining the presence of MERS-CoV infection in dromedary camels.</p>
</list-item>
<list-item id="u0025"><label>•</label>
<p id="p0025">Zoonotic transmission of MERS requires a One Health approach is necessary to prevent, detect, and respond to the disease.</p>
</list-item>
<list-item id="u0030"><label>•</label>
<p id="p0030">The critical needs identified in this report inform the WHO R&D MERS Roadmap and a broader public health research agenda.</p>
</list-item>
</list>
</p>
</abstract>
<kwd-group id="kwrds0010"><title>Keywords</title>
<kwd>MERS-CoV</kwd>
<kwd>Research</kwd>
<kwd>Animal-human interface</kwd>
<kwd>Dromedary camels</kwd>
<kwd>Zoonosis</kwd>
<kwd>Vaccine</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations><list></list>
<tree></tree>
</affiliations>
</record>
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