Psychiatric Findings in Suspected and Confirmed Middle East Respiratory Syndrome Patients Quarantined in Hospital: A Retrospective Chart Analysis
Identifieur interne : 000490 ( Pmc/Checkpoint ); précédent : 000489; suivant : 000491Psychiatric Findings in Suspected and Confirmed Middle East Respiratory Syndrome Patients Quarantined in Hospital: A Retrospective Chart Analysis
Auteurs : Hyun-Chung Kim [Corée du Sud] ; So-Young Yoo [Corée du Sud] ; Bun-Hee Lee [Corée du Sud] ; So Hee Lee [Corée du Sud] ; Hyoung-Shik Shin [Corée du Sud]Source :
- Psychiatry Investigation [ 1738-3684 ] ; 2018.
Abstract
Little is known about the psychiatric complications or risk factors for depression in suspected or confirmed Middle East Respiratory Syndrome (MERS) patients quarantined in hospital.
A retrospective chart review was performed of all the patients admitted to the acute MERS inpatient unit at the NMC during the 2015 outbreak.
30 (75%) were confirmed to be MERS-CoV positive among 40 admitted cases. Among the 24 MERS survivors, 17 (70.8%) exhibited psychiatric symptoms and 10 (41.7%) received a psychiatric diagnosis and medication during their hospital stay. Suspected MERS patients did not exhibit psychiatric symptoms or receive a psychiatric diagnosis. 27 suspected or confirmed MERS patients (age 41.15±18.64, male 37.0%) completed psychological assessments. A multiple linear regression analysis revealed that the Korean National Health and Nutrition Examination Survey-Short form and the Impact of Event Scale-Revised scores were significantly positively correlated with Patient Health Questionnaire-9 scores.
Our findings indicate that the acute treatment of MERS-CoV infections in quarantine had a significant impact on the patients’ mental health. Furthermore, assessment of the risk factors for depression may identify vulnerable patients who require psychiatric care and attention during hospital quarantine.
Url:
DOI: 10.30773/pi.2017.10.25.1
PubMed: 29593206
PubMed Central: 5912494
Affiliations:
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<author><name sortKey="Kim, Hyun Chung" sort="Kim, Hyun Chung" uniqKey="Kim H" first="Hyun-Chung" last="Kim">Hyun-Chung Kim</name>
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<country xml:lang="fr">Corée du Sud</country>
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<author><name sortKey="Yoo, So Young" sort="Yoo, So Young" uniqKey="Yoo S" first="So-Young" last="Yoo">So-Young Yoo</name>
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<author><name sortKey="Lee, Bun Hee" sort="Lee, Bun Hee" uniqKey="Lee B" first="Bun-Hee" last="Lee">Bun-Hee Lee</name>
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<author><name sortKey="Lee, So Hee" sort="Lee, So Hee" uniqKey="Lee S" first="So Hee" last="Lee">So Hee Lee</name>
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<author><name sortKey="Shin, Hyoung Shik" sort="Shin, Hyoung Shik" uniqKey="Shin H" first="Hyoung-Shik" last="Shin">Hyoung-Shik Shin</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Psychiatric Findings in Suspected and Confirmed Middle East Respiratory Syndrome Patients Quarantined in Hospital: A Retrospective Chart Analysis</title>
<author><name sortKey="Kim, Hyun Chung" sort="Kim, Hyun Chung" uniqKey="Kim H" first="Hyun-Chung" last="Kim">Hyun-Chung Kim</name>
<affiliation wicri:level="1"><nlm:aff id="af1-pi-2017-10-25-1">Department of Psychiatry, National Medical Center, Seoul,<country>Republic of Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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</author>
<author><name sortKey="Yoo, So Young" sort="Yoo, So Young" uniqKey="Yoo S" first="So-Young" last="Yoo">So-Young Yoo</name>
<affiliation wicri:level="1"><nlm:aff id="af1-pi-2017-10-25-1">Department of Psychiatry, National Medical Center, Seoul,<country>Republic of Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Lee, Bun Hee" sort="Lee, Bun Hee" uniqKey="Lee B" first="Bun-Hee" last="Lee">Bun-Hee Lee</name>
<affiliation wicri:level="1"><nlm:aff id="af2-pi-2017-10-25-1">Maum & Maum Psychiatric Clinic, Seoul,<country>Republic of Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
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<author><name sortKey="Lee, So Hee" sort="Lee, So Hee" uniqKey="Lee S" first="So Hee" last="Lee">So Hee Lee</name>
<affiliation wicri:level="1"><nlm:aff id="af1-pi-2017-10-25-1">Department of Psychiatry, National Medical Center, Seoul,<country>Republic of Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Shin, Hyoung Shik" sort="Shin, Hyoung Shik" uniqKey="Shin H" first="Hyoung-Shik" last="Shin">Hyoung-Shik Shin</name>
<affiliation wicri:level="1"><nlm:aff id="af3-pi-2017-10-25-1">Center for Infectious Disease, National Medical Center, Seoul,<country>Republic of Korea</country>
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<country xml:lang="fr">Corée du Sud</country>
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<series><title level="j">Psychiatry Investigation</title>
<idno type="ISSN">1738-3684</idno>
<idno type="eISSN">1976-3026</idno>
<imprint><date when="2018">2018</date>
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<front><div type="abstract" xml:lang="en"><sec><title>Objective</title>
<p>Little is known about the psychiatric complications or risk factors for depression in suspected or confirmed Middle East Respiratory Syndrome (MERS) patients quarantined in hospital.</p>
</sec>
<sec><title>Methods</title>
<p>A retrospective chart review was performed of all the patients admitted to the acute MERS inpatient unit at the NMC during the 2015 outbreak.</p>
</sec>
<sec><title>Results</title>
<p>30 (75%) were confirmed to be MERS-CoV positive among 40 admitted cases. Among the 24 MERS survivors, 17 (70.8%) exhibited psychiatric symptoms and 10 (41.7%) received a psychiatric diagnosis and medication during their hospital stay. Suspected MERS patients did not exhibit psychiatric symptoms or receive a psychiatric diagnosis. 27 suspected or confirmed MERS patients (age 41.15±18.64, male 37.0%) completed psychological assessments. A multiple linear regression analysis revealed that the Korean National Health and Nutrition Examination Survey-Short form and the Impact of Event Scale-Revised scores were significantly positively correlated with Patient Health Questionnaire-9 scores.</p>
</sec>
<sec><title>Conclusion</title>
<p>Our findings indicate that the acute treatment of MERS-CoV infections in quarantine had a significant impact on the patients’ mental health. Furthermore, assessment of the risk factors for depression may identify vulnerable patients who require psychiatric care and attention during hospital quarantine.</p>
</sec>
</div>
</front>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Psychiatry Investig</journal-id>
<journal-id journal-id-type="iso-abbrev">Psychiatry Investig</journal-id>
<journal-id journal-id-type="publisher-id">PI</journal-id>
<journal-title-group><journal-title>Psychiatry Investigation</journal-title>
</journal-title-group>
<issn pub-type="ppub">1738-3684</issn>
<issn pub-type="epub">1976-3026</issn>
<publisher><publisher-name>Korean Neuropsychiatric Association</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">29593206</article-id>
<article-id pub-id-type="pmc">5912494</article-id>
<article-id pub-id-type="doi">10.30773/pi.2017.10.25.1</article-id>
<article-id pub-id-type="publisher-id">pi-2017-10-25-1</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Psychiatric Findings in Suspected and Confirmed Middle East Respiratory Syndrome Patients Quarantined in Hospital: A Retrospective Chart Analysis</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Kim</surname>
<given-names>Hyun-Chung</given-names>
</name>
<xref ref-type="aff" rid="af1-pi-2017-10-25-1"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yoo</surname>
<given-names>So-Young</given-names>
</name>
<xref ref-type="aff" rid="af1-pi-2017-10-25-1"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lee</surname>
<given-names>Bun-Hee</given-names>
</name>
<xref ref-type="aff" rid="af2-pi-2017-10-25-1"><sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lee</surname>
<given-names>So Hee</given-names>
</name>
<xref ref-type="corresp" rid="c1-pi-2017-10-25-1"></xref>
<xref ref-type="aff" rid="af1-pi-2017-10-25-1"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shin</surname>
<given-names>Hyoung-Shik</given-names>
</name>
<xref ref-type="corresp" rid="c2-pi-2017-10-25-1"></xref>
<xref ref-type="aff" rid="af3-pi-2017-10-25-1"><sup>3</sup>
</xref>
</contrib>
<aff id="af1-pi-2017-10-25-1"><label>1</label>
Department of Psychiatry, National Medical Center, Seoul,<country>Republic of Korea</country>
</aff>
<aff id="af2-pi-2017-10-25-1"><label>2</label>
Maum & Maum Psychiatric Clinic, Seoul,<country>Republic of Korea</country>
</aff>
<aff id="af3-pi-2017-10-25-1"><label>3</label>
Center for Infectious Disease, National Medical Center, Seoul,<country>Republic of Korea</country>
</aff>
</contrib-group>
<author-notes><corresp id="c1-pi-2017-10-25-1">Correspondence: So Hee Lee, MD, PhD Department of Psychiatry, National Medical Center, 245 Eulji-ro, Jung-gu, Seoul 04564, Republic of Korea Tel: +82-2-2260-7311, Fax: +82-2-2268-5028, E-mail: <email>psyhee@hanmail.net</email>
</corresp>
<corresp id="c2-pi-2017-10-25-1">Correspondence: Hyoung-Shik Shin, MD, PhD Center for Infectious Disease, National Medical Center, 245 Eulji-ro, Jung-gu, Seoul 04564, Republic of Korea Tel: +82-2-2260-7311, Fax: +82-2-2268-5028, E-mail: <email>hyoungsshin@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>4</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub"><day>30</day>
<month>3</month>
<year>2018</year>
</pub-date>
<volume>15</volume>
<issue>4</issue>
<fpage>355</fpage>
<lpage>360</lpage>
<history><date date-type="received"><day>4</day>
<month>7</month>
<year>2017</year>
</date>
<date date-type="rev-recd"><day>24</day>
<month>8</month>
<year>2017</year>
</date>
<date date-type="accepted"><day>25</day>
<month>10</month>
<year>2017</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2018 Korean Neuropsychiatric Association</copyright-statement>
<copyright-year>2018</copyright-year>
<license><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/4.0/">http://creativecommons.org/licenses/by-nc/4.0/</ext-link>
) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><sec><title>Objective</title>
<p>Little is known about the psychiatric complications or risk factors for depression in suspected or confirmed Middle East Respiratory Syndrome (MERS) patients quarantined in hospital.</p>
</sec>
<sec><title>Methods</title>
<p>A retrospective chart review was performed of all the patients admitted to the acute MERS inpatient unit at the NMC during the 2015 outbreak.</p>
</sec>
<sec><title>Results</title>
<p>30 (75%) were confirmed to be MERS-CoV positive among 40 admitted cases. Among the 24 MERS survivors, 17 (70.8%) exhibited psychiatric symptoms and 10 (41.7%) received a psychiatric diagnosis and medication during their hospital stay. Suspected MERS patients did not exhibit psychiatric symptoms or receive a psychiatric diagnosis. 27 suspected or confirmed MERS patients (age 41.15±18.64, male 37.0%) completed psychological assessments. A multiple linear regression analysis revealed that the Korean National Health and Nutrition Examination Survey-Short form and the Impact of Event Scale-Revised scores were significantly positively correlated with Patient Health Questionnaire-9 scores.</p>
</sec>
<sec><title>Conclusion</title>
<p>Our findings indicate that the acute treatment of MERS-CoV infections in quarantine had a significant impact on the patients’ mental health. Furthermore, assessment of the risk factors for depression may identify vulnerable patients who require psychiatric care and attention during hospital quarantine.</p>
</sec>
</abstract>
<kwd-group><kwd>Middle east respiratory syndrome</kwd>
<kwd>Quarantined hospitalization</kwd>
<kwd>Psychiatric symptoms</kwd>
<kwd>Depression</kwd>
<kwd>Emerging infectious diseases</kwd>
</kwd-group>
</article-meta>
</front>
<floats-group><fig id="f1-pi-2017-10-25-1" orientation="portrait" position="float"><label>Figure 1.</label>
<caption><p>Psychiatric complications in patients with MERS during the acute treatment phase. MERS: Middle East respiratory syndrome.</p>
</caption>
<graphic xlink:href="pi-2017-10-25-1f1"></graphic>
</fig>
<table-wrap id="t1-pi-2017-10-25-1" orientation="portrait" position="float"><label>Table 1.</label>
<caption><p>General characteristics of patients who completed the psychological assessment</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="center" valign="middle" rowspan="1" colspan="1">Variables</th>
<th align="center" valign="middle" rowspan="1" colspan="1">Total (N=27)</th>
<th align="center" valign="middle" rowspan="1" colspan="1">Confirmed MERS patients (N=18)</th>
<th align="center" valign="middle" rowspan="1" colspan="1">Suspected MERS Patients (N=9)</th>
<th align="center" valign="middle" rowspan="1" colspan="1">Statistics<sup><xref rid="tfn2-pi-2017-10-25-1" ref-type="table-fn">†</xref>
</sup>
</th>
</tr>
</thead>
<tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Gender, N (%)</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1">χ<sup>2</sup>
=1.271, p=0.406</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Male</td>
<td align="center" valign="top" rowspan="1" colspan="1">10 (37.0)</td>
<td align="center" valign="top" rowspan="1" colspan="1">8 (44.4)</td>
<td align="center" valign="top" rowspan="1" colspan="1">2 (22.2)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Female</td>
<td align="center" valign="top" rowspan="1" colspan="1">17 (63.0)</td>
<td align="center" valign="top" rowspan="1" colspan="1">10 (55.6)</td>
<td align="center" valign="top" rowspan="1" colspan="1">7 (77.8)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Age (year) (mean±SD)</td>
<td align="center" valign="top" rowspan="1" colspan="1">41.15±18.64 (range 21–83)</td>
<td align="center" valign="top" rowspan="1" colspan="1">46.33±18.85</td>
<td align="center" valign="top" rowspan="1" colspan="1">30.78±13.89</td>
<td align="left" valign="top" rowspan="1" colspan="1">t=-2.187, df=25, p=0.038</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Marital status, N (%)</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1">χ<sup>2</sup>
=4.120, p=0.127</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Single</td>
<td align="center" valign="top" rowspan="1" colspan="1">11 (40.7)</td>
<td align="center" valign="top" rowspan="1" colspan="1">5 (27.8)</td>
<td align="center" valign="top" rowspan="1" colspan="1">6 (66.7)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Divorced/separated</td>
<td align="center" valign="top" rowspan="1" colspan="1">2 (7.4)</td>
<td align="center" valign="top" rowspan="1" colspan="1">2 (11.1)</td>
<td align="center" valign="top" rowspan="1" colspan="1">0 (0)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Married</td>
<td align="center" valign="top" rowspan="1" colspan="1">14 (51.9)</td>
<td align="center" valign="top" rowspan="1" colspan="1">11 (61.1)</td>
<td align="center" valign="top" rowspan="1" colspan="1">3 (33.3)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Education, N (%)</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1">χ<sup>2</sup>
=0.750, p=0.667</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> High school or lower</td>
<td align="center" valign="top" rowspan="1" colspan="1">9 (33.3)</td>
<td align="center" valign="top" rowspan="1" colspan="1">7 (38.9)</td>
<td align="center" valign="top" rowspan="1" colspan="1">2 (22.2)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> More than high school</td>
<td align="center" valign="top" rowspan="1" colspan="1">18 (66.7)</td>
<td align="center" valign="top" rowspan="1" colspan="1">11 (61.1)</td>
<td align="center" valign="top" rowspan="1" colspan="1">7 (77.8)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Health care provider<sup><xref rid="tfn1-pi-2017-10-25-1" ref-type="table-fn">*</xref>
</sup>
, N (%)</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1">χ<sup>2</sup>
=4.747, p=0.046</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Yes</td>
<td align="center" valign="top" rowspan="1" colspan="1">13 (48.1)</td>
<td align="center" valign="top" rowspan="1" colspan="1">6 (33.3)</td>
<td align="center" valign="top" rowspan="1" colspan="1">7 (77.8)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> No</td>
<td align="center" valign="top" rowspan="1" colspan="1">14 (51.9)</td>
<td align="center" valign="top" rowspan="1" colspan="1">12 (66.7)</td>
<td align="center" valign="top" rowspan="1" colspan="1">2 (22.2)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Previous medical disease, N (%)</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1">χ<sup>2</sup>
=0.000, p=1.000</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Yes</td>
<td align="center" valign="top" rowspan="1" colspan="1">15 (55.6)</td>
<td align="center" valign="top" rowspan="1" colspan="1">10 (55.6)</td>
<td align="center" valign="top" rowspan="1" colspan="1">5 (55.6)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> No</td>
<td align="center" valign="top" rowspan="1" colspan="1">12 (44.4)</td>
<td align="center" valign="top" rowspan="1" colspan="1">8 (44.4)</td>
<td align="center" valign="top" rowspan="1" colspan="1">4 (44.4)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Previous psychiatric disorders, N (%)</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1">χ<sup>2</sup>
=1.080, p=0.538</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Yes</td>
<td align="center" valign="top" rowspan="1" colspan="1">2 (7.4)</td>
<td align="center" valign="top" rowspan="1" colspan="1">2 (11.1)</td>
<td align="center" valign="top" rowspan="1" colspan="1">0 (0)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> No</td>
<td align="center" valign="top" rowspan="1" colspan="1">25 (92.6)</td>
<td align="center" valign="top" rowspan="1" colspan="1">16 (88.9)</td>
<td align="center" valign="top" rowspan="1" colspan="1">9 (100)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="tfn1-pi-2017-10-25-1"><label>*</label>
<p>a kind of health care provider included medical doctor, nurse, and nurse assistant among job,</p>
</fn>
<fn id="tfn2-pi-2017-10-25-1"><label>†</label>
<p>variables were compared between Confirmed MERS patients and Suspected MERS Patients.</p>
</fn>
<fn><p>MERS: Middle East Respiratory Syndrome</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="t2-pi-2017-10-25-1" orientation="portrait" position="float"><label>Table 2.</label>
<caption><p>Psychological variables according to depression status (N=27)</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="center" valign="middle" rowspan="2" colspan="1">Variables</th>
<th align="center" valign="middle" rowspan="1" colspan="1">No. depression</th>
<th align="center" valign="middle" rowspan="1" colspan="1">Depression<sup><xref rid="tfn3-pi-2017-10-25-1" ref-type="table-fn">*</xref>
</sup>
</th>
<th align="center" valign="middle" rowspan="2" colspan="1">Statistics</th>
</tr>
<tr><th align="center" valign="middle" rowspan="1" colspan="1">PHQ-9 ≤4 (N=16)</th>
<th align="center" valign="middle" rowspan="1" colspan="1">PHQ-9 ≥5 (N=11)</th>
</tr>
</thead>
<tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">KNHANES-Short form (mean±SD)</td>
<td align="center" valign="top" rowspan="1" colspan="1">11.06±2.38</td>
<td align="center" valign="top" rowspan="1" colspan="1">20.64±8.80</td>
<td align="left" valign="top" rowspan="1" colspan="1">t=4.169, df=25, p<0.001</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> IES-R</td>
<td align="center" valign="top" rowspan="1" colspan="1">5.31±8.36</td>
<td align="center" valign="top" rowspan="1" colspan="1">18.09±17.34</td>
<td align="left" valign="top" rowspan="1" colspan="1">t=2.262, df=25, p=0.017</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">PTD-PTNB-PTSS (mean±SD)</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> PTD</td>
<td align="center" valign="top" rowspan="1" colspan="1">3.63±1.09</td>
<td align="center" valign="top" rowspan="1" colspan="1">7.18±4.73</td>
<td align="left" valign="top" rowspan="1" colspan="1">t=2.922, df=25, p=0.007</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> PTNB</td>
<td align="center" valign="top" rowspan="1" colspan="1">12.50±3.08</td>
<td align="center" valign="top" rowspan="1" colspan="1">14.73±5.87</td>
<td align="left" valign="top" rowspan="1" colspan="1">t=1.289, df=25, p=0.209</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> PTSS</td>
<td align="center" valign="top" rowspan="1" colspan="1">5.19±0.54</td>
<td align="center" valign="top" rowspan="1" colspan="1">6.73±3.58</td>
<td align="left" valign="top" rowspan="1" colspan="1">t=1.707, df=25, p=0.100</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="tfn3-pi-2017-10-25-1"><label>*</label>
<p>patients with depression (PHQ-9 ≥5) (N=11) included 8 subjects (29.6%) with mild depression (PHQ-9, 5–9), 2 (7.4%) with moderate depression (PHQ-9, 10–14), and 1 (3.7%) with severe depression (PHQ-9, 20–27).</p>
</fn>
<fn><p>PHQ-9: Patient Health Questionnaire-9, IES-R: the Impact of Event Scale-Revised, PTD-PTNB-PTSS: Peri-traumatic Dissociation-Post-traumatic Negative Beliefs-Post-traumatic Social Support, KNHANES: National Health and Nutrition Examination Survey</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="t3-pi-2017-10-25-1" orientation="portrait" position="float"><label>Table 3.</label>
<caption><p>Correlations between PHQ-9 and the other psychological test scores</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="center" valign="middle" rowspan="2" colspan="1"></th>
<th align="center" valign="middle" rowspan="2" colspan="1">PHQ-9</th>
<th align="center" valign="middle" rowspan="2" colspan="1">KNHANES-short form</th>
<th align="center" valign="middle" rowspan="2" colspan="1">IES-R</th>
<th align="center" valign="middle" colspan="3" rowspan="1">PTD-PTNB-PTSS<hr></hr>
</th>
</tr>
<tr><th align="center" valign="middle" rowspan="1" colspan="1">PTD</th>
<th align="center" valign="middle" rowspan="1" colspan="1">PTNB</th>
<th align="center" valign="middle" rowspan="1" colspan="1">PTSS</th>
</tr>
</thead>
<tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">PHQ-9</td>
<td align="left" valign="top" rowspan="1" colspan="1">1</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">KNHANES-short form</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.814<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">1</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">IES-R</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.679<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.626<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">1</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">PTD-PTNB-PTSS</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> PTD</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.627<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.770<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.630<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">1</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> PTNB</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.454<sup><xref rid="tfn4-pi-2017-10-25-1" ref-type="table-fn">*</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.564<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.751<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.571<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">1</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> PTSS</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.363</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.594<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.786<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.627<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.772<sup><xref rid="tfn5-pi-2017-10-25-1" ref-type="table-fn">**</xref>
</sup>
</td>
<td align="left" valign="top" rowspan="1" colspan="1">1</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="tfn4-pi-2017-10-25-1"><label>*</label>
<p>p<0.05,</p>
</fn>
<fn id="tfn5-pi-2017-10-25-1"><label>**</label>
<p>p<0.001.</p>
</fn>
<fn><p>PHQ-9: Patient Health Questionnaire-9, IES-R: the Impact of Event Scale-Revised, PTD-PTNB-PTSS: Peri-traumatic Dissociation-Post-traumatic Negative Beliefs-Post-traumatic Social Support, KNHANES: National Health and Nutrition Examination Survey</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="t4-pi-2017-10-25-1" orientation="portrait" position="float"><label>Table 4.</label>
<caption><p>Analysis of the relationship between PHQ-9 scores and the IES-R and KNHANES-short form scores</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="center" valign="middle" rowspan="1" colspan="1"></th>
<th align="center" valign="middle" rowspan="1" colspan="1">B</th>
<th align="center" valign="middle" rowspan="1" colspan="1">Standard error</th>
<th align="center" valign="middle" rowspan="1" colspan="1">β</th>
<th align="center" valign="middle" rowspan="1" colspan="1">t</th>
<th align="center" valign="middle" rowspan="1" colspan="1">p</th>
</tr>
</thead>
<tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">(Constant)</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.543</td>
<td align="center" valign="top" rowspan="1" colspan="1">2.211</td>
<td align="center" valign="top" rowspan="1" colspan="1"></td>
<td align="center" valign="top" rowspan="1" colspan="1">0.246</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.808</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">KNHANES-short form</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.485</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.118</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.730</td>
<td align="center" valign="top" rowspan="1" colspan="1">4.120</td>
<td align="center" valign="top" rowspan="1" colspan="1"><0.001</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">IES-R</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.167</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.063</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.473</td>
<td align="center" valign="top" rowspan="1" colspan="1">2.642</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.015</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">PTD</td>
<td align="center" valign="top" rowspan="1" colspan="1">-0.113</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.251</td>
<td align="center" valign="top" rowspan="1" colspan="1">-0.080</td>
<td align="center" valign="top" rowspan="1" colspan="1">-0.451</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.656</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">PTNB</td>
<td align="center" valign="top" rowspan="1" colspan="1">-0.297</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.186</td>
<td align="center" valign="top" rowspan="1" colspan="1">-0.267</td>
<td align="center" valign="top" rowspan="1" colspan="1">-1.597</td>
<td align="center" valign="top" rowspan="1" colspan="1">0.125</td>
</tr>
<tr><td align="center" valign="top" colspan="6" rowspan="1">R<sup>2</sup>
=0.744, Adjusted R<sup>2</sup>
=0.697, F=15.947, p<0.001</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn><p>PHQ-9: Patient Health Questionnaire-9, IES-R: the Impact of Event Scale-Revised, PTD-PTNB-PTSS: Peri-traumatic Dissociation-Posttraumatic Negative Beliefs-Post-traumatic Social Support, KNHANES: National Health and Nutrition Examination Survey</p>
</fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</pmc>
<affiliations><list><country><li>Corée du Sud</li>
</country>
</list>
<tree><country name="Corée du Sud"><noRegion><name sortKey="Kim, Hyun Chung" sort="Kim, Hyun Chung" uniqKey="Kim H" first="Hyun-Chung" last="Kim">Hyun-Chung Kim</name>
</noRegion>
<name sortKey="Lee, Bun Hee" sort="Lee, Bun Hee" uniqKey="Lee B" first="Bun-Hee" last="Lee">Bun-Hee Lee</name>
<name sortKey="Lee, So Hee" sort="Lee, So Hee" uniqKey="Lee S" first="So Hee" last="Lee">So Hee Lee</name>
<name sortKey="Shin, Hyoung Shik" sort="Shin, Hyoung Shik" uniqKey="Shin H" first="Hyoung-Shik" last="Shin">Hyoung-Shik Shin</name>
<name sortKey="Yoo, So Young" sort="Yoo, So Young" uniqKey="Yoo S" first="So-Young" last="Yoo">So-Young Yoo</name>
</country>
</tree>
</affiliations>
</record>
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