The Middle East Respiratory Syndrome (MERS)
Identifieur interne : 000157 ( Pmc/Checkpoint ); précédent : 000156; suivant : 000158The Middle East Respiratory Syndrome (MERS)
Auteurs : Esam I. Azhar [Arabie saoudite] ; David S. C. Hui [Hong Kong] ; Ziad A. Memish [Arabie saoudite] ; Christian Drosten [Allemagne] ; Alimuddin Zumla [Royaume-Uni]Source :
- Infectious Disease Clinics of North America [ 0891-5520 ] ; 2019.
Abstract
The Middle East respiratory syndrome (MERS) is a novel lethal zoonotic disease of humans caused by the MERS coronavirus (MERS-CoV). Although MERS is endemic to the Middle East, travelers have exported MERS-CoV on return to their home countries. Clinical manifestations range from mild to severe acute respiratory disease and death. The elderly, immunocompromised, and those with chronic comorbid liver, lung, and hepatic conditions have a high mortality rate. There is no specific treatment. Person-to-person spread causes hospital and household outbreaks, and thus improved compliance with internationally recommended infection control protocols and rapid implementation of infection control measures are required.
Url:
DOI: 10.1016/j.idc.2019.08.001
PubMed: 31668197
PubMed Central: 7127753
Affiliations:
- Allemagne, Arabie saoudite, Hong Kong, Royaume-Uni
- Angleterre, Berlin, Grand Londres
- Berlin, Londres, Sha Tin
- University College de Londres, Université chinoise de Hong Kong
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PMC:7127753Le document en format XML
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Azhar</name><affiliation wicri:level="1"><nlm:aff id="aff1">Special Infectious Agents Unit, King Fahd Medical Research Centre, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Special Infectious Agents Unit, King Fahd Medical Research Centre, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah</wicri:regionArea><wicri:noRegion>Jeddah</wicri:noRegion></affiliation></author><author><name sortKey="Hui, David S C" sort="Hui, David S C" uniqKey="Hui D" first="David S. C." last="Hui">David S. C. 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Although MERS is endemic to the Middle East, travelers have exported MERS-CoV on return to their home countries. Clinical manifestations range from mild to severe acute respiratory disease and death. The elderly, immunocompromised, and those with chronic comorbid liver, lung, and hepatic conditions have a high mortality rate. There is no specific treatment. Person-to-person spread causes hospital and household outbreaks, and thus improved compliance with internationally recommended infection control protocols and rapid implementation of infection control measures are required.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zumla, A" uniqKey="Zumla A">A. Zumla</name></author><author><name sortKey="Hui, D S" uniqKey="Hui D">D.S. Hui</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Infect Dis Clin North Am</journal-id><journal-id journal-id-type="iso-abbrev">Infect. Dis. Clin. North Am</journal-id><journal-title-group><journal-title>Infectious Disease Clinics of North America</journal-title></journal-title-group><issn pub-type="ppub">0891-5520</issn><issn pub-type="epub">1557-9824</issn><publisher><publisher-name>Elsevier Inc.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31668197</article-id><article-id pub-id-type="pmc">7127753</article-id><article-id pub-id-type="publisher-id">S0891-5520(19)30060-1</article-id><article-id pub-id-type="doi">10.1016/j.idc.2019.08.001</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The Middle East Respiratory Syndrome (MERS)</article-title></title-group><contrib-group><contrib contrib-type="author" id="au1"><name><surname>Azhar</surname><given-names>Esam I.</given-names></name><degrees>PhD, FRCP</degrees><email>eazhar@kau.edu.sa</email><xref rid="aff1" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">∗</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Hui</surname><given-names>David S.C.</given-names></name><degrees>MBBS, MD(UNSW), FRACP, FRCP(Lond, Edin, Glasg), FHKCP, FHKAM(Med)</degrees><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au3"><name><surname>Memish</surname><given-names>Ziad A.</given-names></name><degrees>MD, FRCP</degrees><xref rid="aff3" ref-type="aff">c</xref><xref rid="aff4" ref-type="aff">d</xref></contrib><contrib contrib-type="author" id="au4"><name><surname>Drosten</surname><given-names>Christian</given-names></name><degrees>PhD</degrees><xref rid="aff5" ref-type="aff">e</xref></contrib><contrib contrib-type="author" id="au5"><name><surname>Zumla</surname><given-names>Alimuddin</given-names></name><degrees>MBChB, MSc, PhD, MD, FRCP(Lond), FRCP(Edin), FRCPath(UK), FAAS</degrees><xref rid="aff6" ref-type="aff">f</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Special Infectious Agents Unit, King Fahd Medical Research Centre, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia</aff><aff id="aff2"><label>b</label>Department of Medicine and Therapeutics, Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong</aff><aff id="aff3"><label>c</label>College of Medicine, Alfaisal University, Riyadh, Saudi Arabia</aff><aff id="aff4"><label>d</label>Infectious Diseases Division, Department of Medicine and Research, Prince Mohamed Bin Abdulaziz Hospital, Ministry of Health, Riyadh, Saudi Arabia</aff><aff id="aff5"><label>e</label>Institute of Virology, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Berlin Institute of Health, Berlin, Germany</aff><aff id="aff6"><label>f</label>Center for Clinical Microbiology, University College London, Royal Free Campus 2nd Floor, Rowland Hill Street, London NW3 2PF, United Kingdom</aff><author-notes><corresp id="cor1"><label>∗</label>Corresponding author. <email>eazhar@kau.edu.sa</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>25</day><month>10</month><year>2019</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>12</month><year>2019</year></pub-date><pub-date pub-type="epub"><day>25</day><month>10</month><year>2019</year></pub-date><volume>33</volume><issue>4</issue><fpage>891</fpage><lpage>905</lpage><permissions><copyright-statement>© 2019 Elsevier Inc. All rights reserved.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder>Elsevier Inc.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract abstract-type="teaser" id="abs0010"><p>The Middle East respiratory syndrome (MERS) is a novel lethal zoonotic disease of humans caused by the MERS coronavirus (MERS-CoV). Although MERS is endemic to the Middle East, travelers have exported MERS-CoV on return to their home countries. Clinical manifestations range from mild to severe acute respiratory disease and death. The elderly, immunocompromised, and those with chronic comorbid liver, lung, and hepatic conditions have a high mortality rate. There is no specific treatment. Person-to-person spread causes hospital and household outbreaks, and thus improved compliance with internationally recommended infection control protocols and rapid implementation of infection control measures are required.</p></abstract><kwd-group id="kwrds0010"><title>Keywords</title><kwd>Middle East respiratory syndrome coronavirus</kwd><kwd>MERS-CoV</kwd><kwd>Epidemiology diagnosis</kwd><kwd>Treatment</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Allemagne</li><li>Arabie saoudite</li><li>Hong Kong</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Berlin</li><li>Grand Londres</li></region><settlement><li>Berlin</li><li>Londres</li><li>Sha Tin</li></settlement><orgName><li>University College de Londres</li><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="Arabie saoudite"><noRegion><name sortKey="Azhar, Esam I" sort="Azhar, Esam I" uniqKey="Azhar E" first="Esam I." last="Azhar">Esam I. Azhar</name></noRegion><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. Memish</name><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. Memish</name></country><country name="Hong Kong"><noRegion><name sortKey="Hui, David S C" sort="Hui, David S C" uniqKey="Hui D" first="David S. C." last="Hui">David S. C. Hui</name></noRegion></country><country name="Allemagne"><region name="Berlin"><name sortKey="Drosten, Christian" sort="Drosten, Christian" uniqKey="Drosten C" first="Christian" last="Drosten">Christian Drosten</name></region></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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