Serveur d'exploration MERS

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Application of a quantitative entry assessment model to compare the relative risk of incursion of zoonotic bat-borne viruses into European Union Member States

Identifieur interne : 002794 ( Ncbi/Merge ); précédent : 002793; suivant : 002795

Application of a quantitative entry assessment model to compare the relative risk of incursion of zoonotic bat-borne viruses into European Union Member States

Auteurs : Verity Horigan [Royaume-Uni] ; Paul Gale [Royaume-Uni] ; Rowena D. Kosmider [Royaume-Uni] ; Christopher Minnis [Royaume-Uni] ; Emma L. Snary [Royaume-Uni] ; Andrew C. Breed [Royaume-Uni] ; Robin R. L. Simons [Royaume-Uni]

Source :

RBID : PMC:7103962

Abstract

Highlights

Risk assessment for entry of zoonotic bat-borne viruses into the European Union.

Comparison of relative risk of incursion of five viruses by four routes.

An Ebola outbreak similar to 2013–2016 posed the highest risk of introduction.

Relative risk to countries varied due to extent of global trade and human travel.

Model provides a horizon scanning tool for use when available data is limited.


Url:
DOI: 10.1016/j.mran.2017.09.002
PubMed: 32289058
PubMed Central: 7103962

Links toward previous steps (curation, corpus...)


Links to Exploration step

PMC:7103962

Le document en format XML

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<p id="para0001">Risk assessment for entry of zoonotic bat-borne viruses into the European Union.</p>
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<p id="para0002">Comparison of relative risk of incursion of five viruses by four routes.</p>
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<p id="para0003">An Ebola outbreak similar to 2013–2016 posed the highest risk of introduction.</p>
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<p id="para0004">Relative risk to countries varied due to extent of global trade and human travel.</p>
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<title level="j">Microbial Risk Analysis</title>
<idno type="ISSN">2352-3522</idno>
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<title>Highlights</title>
<p>
<list list-type="simple" id="celist0001">
<list-item id="celistitem0001">
<label></label>
<p id="para0001">Risk assessment for entry of zoonotic bat-borne viruses into the European Union.</p>
</list-item>
<list-item id="celistitem0002">
<label></label>
<p id="para0002">Comparison of relative risk of incursion of five viruses by four routes.</p>
</list-item>
<list-item id="celistitem0003">
<label></label>
<p id="para0003">An Ebola outbreak similar to 2013–2016 posed the highest risk of introduction.</p>
</list-item>
<list-item id="celistitem0004">
<label></label>
<p id="para0004">Relative risk to countries varied due to extent of global trade and human travel.</p>
</list-item>
<list-item id="celistitem0005">
<label></label>
<p id="para0005">Model provides a horizon scanning tool for use when available data is limited.</p>
</list-item>
</list>
</p>
</div>
</front>
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<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
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<author>
<name sortKey="Minnis, Christopher" sort="Minnis, Christopher" uniqKey="Minnis C" first="Christopher" last="Minnis">Christopher Minnis</name>
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<nlm:affiliation>The Royal Veterinary College, Royal College Street, London, England NW1 0TU, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>The Royal Veterinary College, Royal College Street, London, England NW1 0TU</wicri:regionArea>
<wicri:noRegion>England NW1 0TU</wicri:noRegion>
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<name sortKey="Snary, Emma L" sort="Snary, Emma L" uniqKey="Snary E" first="Emma L" last="Snary">Emma L. Snary</name>
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<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
</affiliation>
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<name sortKey="Breed, Andrew C" sort="Breed, Andrew C" uniqKey="Breed A" first="Andrew C" last="Breed">Andrew C. Breed</name>
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<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
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<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
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<name sortKey="Simons, Robin R L" sort="Simons, Robin R L" uniqKey="Simons R" first="Robin R L" last="Simons">Robin R L. Simons</name>
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<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
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<idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:32289058</idno>
<idno type="pmid">32289058</idno>
<idno type="doi">10.1016/j.mran.2017.09.002</idno>
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<title xml:lang="en">Application of a quantitative entry assessment model to compare the relative risk of incursion of zoonotic bat-borne viruses into European Union Member States.</title>
<author>
<name sortKey="Horigan, Verity" sort="Horigan, Verity" uniqKey="Horigan V" first="Verity" last="Horigan">Verity Horigan</name>
<affiliation wicri:level="1">
<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Gale, Paul" sort="Gale, Paul" uniqKey="Gale P" first="Paul" last="Gale">Paul Gale</name>
<affiliation wicri:level="1">
<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kosmider, Rowena D" sort="Kosmider, Rowena D" uniqKey="Kosmider R" first="Rowena D" last="Kosmider">Rowena D. Kosmider</name>
<affiliation wicri:level="1">
<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Minnis, Christopher" sort="Minnis, Christopher" uniqKey="Minnis C" first="Christopher" last="Minnis">Christopher Minnis</name>
<affiliation wicri:level="1">
<nlm:affiliation>The Royal Veterinary College, Royal College Street, London, England NW1 0TU, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>The Royal Veterinary College, Royal College Street, London, England NW1 0TU</wicri:regionArea>
<wicri:noRegion>England NW1 0TU</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Snary, Emma L" sort="Snary, Emma L" uniqKey="Snary E" first="Emma L" last="Snary">Emma L. Snary</name>
<affiliation wicri:level="1">
<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Breed, Andrew C" sort="Breed, Andrew C" uniqKey="Breed A" first="Andrew C" last="Breed">Andrew C. Breed</name>
<affiliation wicri:level="1">
<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Simons, Robin R L" sort="Simons, Robin R L" uniqKey="Simons R" first="Robin R L" last="Simons">Robin R L. Simons</name>
<affiliation wicri:level="1">
<nlm:affiliation>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Animal and Plant Health Agency (APHA), Department of Epidemiological Sciences, New Haw, Addlestone, Surrey KT15 3NB</wicri:regionArea>
<wicri:noRegion>Surrey KT15 3NB</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Microbial risk analysis</title>
<idno type="eISSN">2352-3530</idno>
<imprint>
<date when="2017" type="published">2017</date>
</imprint>
</series>
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<front>
<div type="abstract" xml:lang="en">This paper presents a quantitative assessment model for the risk of entry of zoonotic bat-borne viruses into the European Union (EU). The model considers four routes of introduction: human travel, legal trade of products, live animal imports and illegal import of bushmeat and was applied to five virus outbreak scenarios. Two scenarios were considered for
<i>Zaire ebolavirus</i>
(wEBOV, cEBOV) and other scenarios for Hendra virus, Marburg virus (MARV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The use of the same framework and generic data sources for all EU Member States (MS) allows for a relative comparison of the probability of virus introduction and of the importance of the routes of introduction among MSs. According to the model wEBOV posed the highest risk of an introduction event within the EU, followed by MARV and MERS-CoV. However, the main route of introduction differed, with wEBOV and MERS-CoV most likely through human travel and MARV through legal trade of foodstuffs. The relative risks to EU MSs as entry points also varied between outbreak scenarios, highlighting the heterogeneity in global trade and travel to the EU MSs. The model has the capability to allow for a continual updating of the risk estimate using new data as, and when, it becomes available. The model provides an horizon scanning tool for use when available data are limited and, therefore, the absolute risk estimates often have high uncertainty. Sensitivity analysis suggested virus prevalence in bats has a large influence on the results; a 90% reduction in prevalence reduced the risk of introduction considerably and resulted in the relative ranking of MARV falling below that for MERS-CoV, due to this parameter disproportionately affecting the risk of introduction from the trade route over human travel.</div>
</front>
</TEI>
</pubmed>
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