Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).
Identifieur interne : 002756 ( Ncbi/Merge ); précédent : 002755; suivant : 002757Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).
Auteurs : Joshua White [États-Unis]Source :
- Clinical microbiology newsletter [ 0196-4399 ] ; 2014.
Abstract
First reported in September 2012, the Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) has resulted in 206 laboratory-confirmed deaths, with a 42% mortality rate as of 27 March 2014. Closely related coronaviruses have been isolated in bats, but most evidence suggests that humans have become infected directly from camels in a number of separate transmission events, with limited human-to-human transmission reported thus far. The majority of cases originated in the Middle East (predominantly Saudi Arabia), including all the index cases. Clinical manifestations primarily involve fever, chills, and rapidly progressive respiratory failure, often resulting in an acute respiratory distress syndrome, with a minority of patients reporting gastrointestinal symptoms, as well. The majority of critically ill patients are older males with medical co-morbidities, and a large number of minimally symptomatic cases likely go undetected. Unfortunately, attempted therapies have all been unsuccessful thus far, and treatment remains supportive care.
DOI: 10.1016/j.clinmicnews.2014.07.002
PubMed: 32287683
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).</title><author><name sortKey="White, Joshua" sort="White, Joshua" uniqKey="White J" first="Joshua" last="White">Joshua White</name><affiliation wicri:level="2"><nlm:affiliation>Virginia Commonwealth University Health Systems, Richmond, Virginia.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Virginia Commonwealth University Health Systems, Richmond</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:32287683</idno><idno type="pmid">32287683</idno><idno type="doi">10.1016/j.clinmicnews.2014.07.002</idno><idno type="wicri:Area/PubMed/Corpus">001891</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001891</idno><idno type="wicri:Area/PubMed/Curation">001891</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001891</idno><idno type="wicri:Area/PubMed/Checkpoint">001804</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001804</idno><idno type="wicri:Area/Ncbi/Merge">002756</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).</title><author><name sortKey="White, Joshua" sort="White, Joshua" uniqKey="White J" first="Joshua" last="White">Joshua White</name><affiliation wicri:level="2"><nlm:affiliation>Virginia Commonwealth University Health Systems, Richmond, Virginia.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Virginia Commonwealth University Health Systems, Richmond</wicri:cityArea></affiliation></author></analytic><series><title level="j">Clinical microbiology newsletter</title><idno type="ISSN">0196-4399</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">First reported in September 2012, the Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) has resulted in 206 laboratory-confirmed deaths, with a 42% mortality rate as of 27 March 2014. Closely related coronaviruses have been isolated in bats, but most evidence suggests that humans have become infected directly from camels in a number of separate transmission events, with limited human-to-human transmission reported thus far. The majority of cases originated in the Middle East (predominantly Saudi Arabia), including all the index cases. Clinical manifestations primarily involve fever, chills, and rapidly progressive respiratory failure, often resulting in an acute respiratory distress syndrome, with a minority of patients reporting gastrointestinal symptoms, as well. The majority of critically ill patients are older males with medical co-morbidities, and a large number of minimally symptomatic cases likely go undetected. Unfortunately, attempted therapies have all been unsuccessful thus far, and treatment remains supportive care.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32287683</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0196-4399</ISSN><JournalIssue CitedMedium="Print"><Volume>36</Volume><Issue>15</Issue><PubDate><Year>2014</Year><Month>Aug</Month><Day>01</Day></PubDate></JournalIssue><Title>Clinical microbiology newsletter</Title><ISOAbbreviation>Clin. Microbiol. Newsl.</ISOAbbreviation></Journal><ArticleTitle>Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).</ArticleTitle><Pagination><MedlinePgn>115-122</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.clinmicnews.2014.07.002</ELocationID><Abstract><AbstractText>First reported in September 2012, the Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) has resulted in 206 laboratory-confirmed deaths, with a 42% mortality rate as of 27 March 2014. Closely related coronaviruses have been isolated in bats, but most evidence suggests that humans have become infected directly from camels in a number of separate transmission events, with limited human-to-human transmission reported thus far. The majority of cases originated in the Middle East (predominantly Saudi Arabia), including all the index cases. Clinical manifestations primarily involve fever, chills, and rapidly progressive respiratory failure, often resulting in an acute respiratory distress syndrome, with a minority of patients reporting gastrointestinal symptoms, as well. The majority of critically ill patients are older males with medical co-morbidities, and a large number of minimally symptomatic cases likely go undetected. Unfortunately, attempted therapies have all been unsuccessful thus far, and treatment remains supportive care.</AbstractText><CopyrightInformation>Copyright © 2014 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>White</LastName><ForeName>Joshua</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Virginia Commonwealth University Health Systems, Richmond, Virginia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>07</Month><Day>25</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Clin Microbiol Newsl</MedlineTA><NlmUniqueID>7909253</NlmUniqueID><ISSNLinking>0196-4399</ISSNLinking></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>8</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>8</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32287683</ArticleId><ArticleId IdType="doi">10.1016/j.clinmicnews.2014.07.002</ArticleId><ArticleId IdType="pii">S0196-4399(14)00051-8</ArticleId><ArticleId IdType="pmc">PMC7132497</ArticleId></ArticleIdList><pmc-dir>pmcsd</pmc-dir>
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