Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak
Identifieur interne : 001869 ( Ncbi/Merge ); précédent : 001868; suivant : 001870Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak
Auteurs : Ga Eun Park [Corée du Sud] ; Cheol-In Kang [Corée du Sud] ; Jae-Hoon Ko [Corée du Sud] ; Sun Young Cho [Corée du Sud] ; Young Eun Ha [Corée du Sud] ; Yae-Jean Kim [Corée du Sud] ; Kyong Ran Peck [Corée du Sud] ; Jae-Hoon Song [Corée du Sud] ; Doo Ryeon Chung [Corée du Sud]Source :
- Journal of Korean Medical Science [ 1011-8934 ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Femelle, Flambées de maladies, Humains, Hyperleucocytose (étiologie), Infections à coronavirus (diagnostic), Infections à coronavirus (épidémiologie), Leucocytes (cytologie), Leucocytes (métabolisme), Marqueurs biologiques (analyse), Marqueurs biologiques (sang), Mâle, Numération des leucocytes, Odds ratio, Protéine C-réactive (analyse), Valeur prédictive des tests, Études cas-témoins.
- MESH :
- analyse : Marqueurs biologiques, Protéine C-réactive.
- cytologie : Leucocytes.
- diagnostic : Infections à coronavirus.
- métabolisme : Leucocytes.
- sang : Marqueurs biologiques.
- épidémiologie : Infections à coronavirus.
- étiologie : Hyperleucocytose.
- Adulte, Adulte d'âge moyen, Femelle, Flambées de maladies, Humains, Mâle, Numération des leucocytes, Odds ratio, Valeur prédictive des tests, Études cas-témoins.
English descriptors
- KwdEn :
- Adult, Biomarkers (analysis), Biomarkers (blood), C-Reactive Protein (analysis), Case-Control Studies, Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Disease Outbreaks, Female, Humans, Leukocyte Count, Leukocytes (cytology), Leukocytes (metabolism), Leukocytosis (etiology), Male, Middle Aged, Odds Ratio, Predictive Value of Tests.
- MESH :
- chemical , analysis : Biomarkers, C-Reactive Protein.
- chemical , blood : Biomarkers.
- cytology : Leukocytes.
- diagnosis : Coronavirus Infections.
- epidemiology : Coronavirus Infections.
- etiology : Leukocytosis.
- metabolism : Leukocytes.
- Adult, Case-Control Studies, Disease Outbreaks, Female, Humans, Leukocyte Count, Male, Middle Aged, Odds Ratio, Predictive Value of Tests.
Abstract
A case-control study was performed to identify clinical predictors for Middle East respiratory syndrome coronavirus (MERS-CoV) infection among patients with acute febrile illness during the nosocomial outbreak. Patients with MERS-CoV were more likely to have monocytosis with normal white blood cell (WBC) count and lower C-reactive protein (CRP) level. Simple laboratory data such as complete blood counts (CBC) with differential count could be a useful marker for the prediction of MERS and triage at the initial presentation of acute febrile patients in outbreak setting.
Url:
DOI: 10.3346/jkms.2017.32.1.151
PubMed: 27914145
PubMed Central: 5143288
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PMC:5143288Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>A case-control study was performed to identify clinical predictors for Middle East respiratory syndrome coronavirus (MERS-CoV) infection among patients with acute febrile illness during the nosocomial outbreak. Patients with MERS-CoV were more likely to have monocytosis with normal white blood cell (WBC) count and lower C-reactive protein (CRP) level. Simple laboratory data such as complete blood counts (CBC) with differential count could be a useful marker for the prediction of MERS and triage at the initial presentation of acute febrile patients in outbreak setting.</p>
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<double pmid="27914145"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak</title>
<author><name sortKey="Park, Ga Eun" sort="Park, Ga Eun" uniqKey="Park G" first="Ga Eun" last="Park">Ga Eun Park</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kang, Cheol In" sort="Kang, Cheol In" uniqKey="Kang C" first="Cheol-In" last="Kang">Cheol-In Kang</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ko, Jae Hoon" sort="Ko, Jae Hoon" uniqKey="Ko J" first="Jae-Hoon" last="Ko">Jae-Hoon Ko</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cho, Sun Young" sort="Cho, Sun Young" uniqKey="Cho S" first="Sun Young" last="Cho">Sun Young Cho</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ha, Young Eun" sort="Ha, Young Eun" uniqKey="Ha Y" first="Young Eun" last="Ha">Young Eun Ha</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kim, Yae Jean" sort="Kim, Yae Jean" uniqKey="Kim Y" first="Yae-Jean" last="Kim">Yae-Jean Kim</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peck, Kyong Ran" sort="Peck, Kyong Ran" uniqKey="Peck K" first="Kyong Ran" last="Peck">Kyong Ran Peck</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Song, Jae Hoon" sort="Song, Jae Hoon" uniqKey="Song J" first="Jae-Hoon" last="Song">Jae-Hoon Song</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chung, Doo Ryeon" sort="Chung, Doo Ryeon" uniqKey="Chung D" first="Doo Ryeon" last="Chung">Doo Ryeon Chung</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
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<idno type="pmid">27914145</idno>
<idno type="pmc">5143288</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143288</idno>
<idno type="RBID">PMC:5143288</idno>
<idno type="doi">10.3346/jkms.2017.32.1.151</idno>
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<idno type="wicri:Area/Pmc/Corpus">000720</idno>
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<idno type="wicri:Area/Pmc/Checkpoint">000B98</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B98</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak</title>
<author><name sortKey="Park, Ga Eun" sort="Park, Ga Eun" uniqKey="Park G" first="Ga Eun" last="Park">Ga Eun Park</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kang, Cheol In" sort="Kang, Cheol In" uniqKey="Kang C" first="Cheol-In" last="Kang">Cheol-In Kang</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
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<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cho, Sun Young" sort="Cho, Sun Young" uniqKey="Cho S" first="Sun Young" last="Cho">Sun Young Cho</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ha, Young Eun" sort="Ha, Young Eun" uniqKey="Ha Y" first="Young Eun" last="Ha">Young Eun Ha</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kim, Yae Jean" sort="Kim, Yae Jean" uniqKey="Kim Y" first="Yae-Jean" last="Kim">Yae-Jean Kim</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peck, Kyong Ran" sort="Peck, Kyong Ran" uniqKey="Peck K" first="Kyong Ran" last="Peck">Kyong Ran Peck</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Song, Jae Hoon" sort="Song, Jae Hoon" uniqKey="Song J" first="Jae-Hoon" last="Song">Jae-Hoon Song</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chung, Doo Ryeon" sort="Chung, Doo Ryeon" uniqKey="Chung D" first="Doo Ryeon" last="Chung">Doo Ryeon Chung</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,<country>Korea</country>
.</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Korean Medical Science</title>
<idno type="ISSN">1011-8934</idno>
<idno type="eISSN">1598-6357</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
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</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>A case-control study was performed to identify clinical predictors for Middle East respiratory syndrome coronavirus (MERS-CoV) infection among patients with acute febrile illness during the nosocomial outbreak. Patients with MERS-CoV were more likely to have monocytosis with normal white blood cell (WBC) count and lower C-reactive protein (CRP) level. Simple laboratory data such as complete blood counts (CBC) with differential count could be a useful marker for the prediction of MERS and triage at the initial presentation of acute febrile patients in outbreak setting.</p>
</div>
</front>
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<pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak.</title>
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</author>
<author><name sortKey="Kang, Cheol In" sort="Kang, Cheol In" uniqKey="Kang C" first="Cheol In" last="Kang">Cheol In Kang</name>
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<author><name sortKey="Cho, Sun Young" sort="Cho, Sun Young" uniqKey="Cho S" first="Sun Young" last="Cho">Sun Young Cho</name>
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<author><name sortKey="Kim, Yae Jean" sort="Kim, Yae Jean" uniqKey="Kim Y" first="Yae Jean" last="Kim">Yae Jean Kim</name>
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<author><name sortKey="Peck, Kyong Ran" sort="Peck, Kyong Ran" uniqKey="Peck K" first="Kyong Ran" last="Peck">Kyong Ran Peck</name>
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<author><name sortKey="Chung, Doo Ryeon" sort="Chung, Doo Ryeon" uniqKey="Chung D" first="Doo Ryeon" last="Chung">Doo Ryeon Chung</name>
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<author><name sortKey="Park, Ga Eun" sort="Park, Ga Eun" uniqKey="Park G" first="Ga Eun" last="Park">Ga Eun Park</name>
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<country xml:lang="fr">Corée du Sud</country>
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<placeName><settlement type="city">Séoul</settlement>
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<author><name sortKey="Kang, Cheol In" sort="Kang, Cheol In" uniqKey="Kang C" first="Cheol In" last="Kang">Cheol In Kang</name>
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<placeName><settlement type="city">Séoul</settlement>
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<author><name sortKey="Ko, Jae Hoon" sort="Ko, Jae Hoon" uniqKey="Ko J" first="Jae Hoon" last="Ko">Jae Hoon Ko</name>
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<author><name sortKey="Cho, Sun Young" sort="Cho, Sun Young" uniqKey="Cho S" first="Sun Young" last="Cho">Sun Young Cho</name>
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<country xml:lang="fr">Corée du Sud</country>
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<author><name sortKey="Ha, Young Eun" sort="Ha, Young Eun" uniqKey="Ha Y" first="Young Eun" last="Ha">Young Eun Ha</name>
<affiliation wicri:level="3"><nlm:affiliation>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
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<placeName><settlement type="city">Séoul</settlement>
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<author><name sortKey="Kim, Yae Jean" sort="Kim, Yae Jean" uniqKey="Kim Y" first="Yae Jean" last="Kim">Yae Jean Kim</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
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<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Peck, Kyong Ran" sort="Peck, Kyong Ran" uniqKey="Peck K" first="Kyong Ran" last="Peck">Kyong Ran Peck</name>
<affiliation wicri:level="3"><nlm:affiliation>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
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<placeName><settlement type="city">Séoul</settlement>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Song, Jae Hoon" sort="Song, Jae Hoon" uniqKey="Song J" first="Jae Hoon" last="Song">Jae Hoon Song</name>
<affiliation wicri:level="3"><nlm:affiliation>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
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<placeName><settlement type="city">Séoul</settlement>
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</author>
<author><name sortKey="Chung, Doo Ryeon" sort="Chung, Doo Ryeon" uniqKey="Chung D" first="Doo Ryeon" last="Chung">Doo Ryeon Chung</name>
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<series><title level="j">Journal of Korean medical science</title>
<idno type="eISSN">1598-6357</idno>
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<term>Biomarkers (analysis)</term>
<term>Biomarkers (blood)</term>
<term>C-Reactive Protein (analysis)</term>
<term>Case-Control Studies</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (epidemiology)</term>
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<term>Infections à coronavirus (épidémiologie)</term>
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<term>Leucocytes (métabolisme)</term>
<term>Marqueurs biologiques (analyse)</term>
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<term>Numération des leucocytes</term>
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<term>Protéine C-réactive (analyse)</term>
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<term>Études cas-témoins</term>
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<term>Protéine C-réactive</term>
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</keywords>
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</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Case-Control Studies</term>
<term>Disease Outbreaks</term>
<term>Female</term>
<term>Humans</term>
<term>Leukocyte Count</term>
<term>Male</term>
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<term>Predictive Value of Tests</term>
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<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Flambées de maladies</term>
<term>Humains</term>
<term>Mâle</term>
<term>Numération des leucocytes</term>
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<front><div type="abstract" xml:lang="en">A case-control study was performed to identify clinical predictors for Middle East respiratory syndrome coronavirus (MERS-CoV) infection among patients with acute febrile illness during the nosocomial outbreak. Patients with MERS-CoV were more likely to have monocytosis with normal white blood cell (WBC) count and lower C-reactive protein (CRP) level. Simple laboratory data such as complete blood counts (CBC) with differential count could be a useful marker for the prediction of MERS and triage at the initial presentation of acute febrile patients in outbreak setting.</div>
</front>
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