MersV1, Ncbi, Merge, bibRecord, 001034

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Identifieur interne : 001034 ( Ncbi/Merge ); précédent : 001033; suivant : 001035

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Auteurs : Kayla M. Peck [États-Unis] ; Adam S. Cockrell [États-Unis] ; Boyd L. Yount [États-Unis] ; Trevor Scobey [États-Unis] ; Ralph S. Baric [États-Unis] ; Mark T. Heise [États-Unis]

Source :

Journal of virology [ 1098-5514 ] ; 2015.

RBID : pubmed:25653445

Descripteurs français

English descriptors

KwdEn :
- Amino Acid Sequence, Animals, Coronavirus Infections (prevention & control), Dipeptidyl Peptidase 4 (chemistry), Dipeptidyl Peptidase 4 (genetics), Dipeptidyl Peptidase 4 (metabolism), Fluorescent Antibody Technique, Glycosylation, Mice, Middle East Respiratory Syndrome Coronavirus (metabolism), Models, Molecular, Molecular Sequence Data, Species Specificity, Virus Internalization.
MESH :
- chemical , chemistry : Dipeptidyl Peptidase 4.
- chemical , genetics : Dipeptidyl Peptidase 4.
- chemical , metabolism : Dipeptidyl Peptidase 4.
- metabolism : Middle East Respiratory Syndrome Coronavirus.
- prevention & control : Coronavirus Infections.
- Amino Acid Sequence, Animals, Fluorescent Antibody Technique, Glycosylation, Mice, Models, Molecular, Molecular Sequence Data, Species Specificity, Virus Internalization.

Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) utilizes dipeptidyl peptidase 4 (DPP4) as an entry receptor. Mouse DPP4 (mDPP4) does not support MERS-CoV entry; however, changes at positions 288 and 330 can confer permissivity. Position 330 changes the charge and glycosylation state of mDPP4. We show that glycosylation is a major factor impacting DPP4 receptor function. These results provide insight into DPP4 species-specific differences impacting MERS-CoV host range and may inform MERS-CoV mouse model development.

DOI: 10.1128/JVI.03445-14
PubMed: 25653445

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 001707
to stream PubMed, to step Curation: 001707
to stream PubMed, to step Checkpoint: 001537

Links to Exploration step

pubmed:25653445

Le document en format XML

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<front><div type="abstract" xml:lang="en">Middle East respiratory syndrome coronavirus (MERS-CoV) utilizes dipeptidyl peptidase 4 (DPP4) as an entry receptor. Mouse DPP4 (mDPP4) does not support MERS-CoV entry; however, changes at positions 288 and 330 can confer permissivity. Position 330 changes the charge and glycosylation state of mDPP4. We show that glycosylation is a major factor impacting DPP4 receptor function. These results provide insight into DPP4 species-specific differences impacting MERS-CoV host range and may inform MERS-CoV mouse model development. </div>
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<Abstract><AbstractText>Middle East respiratory syndrome coronavirus (MERS-CoV) utilizes dipeptidyl peptidase 4 (DPP4) as an entry receptor. Mouse DPP4 (mDPP4) does not support MERS-CoV entry; however, changes at positions 288 and 330 can confer permissivity. Position 330 changes the charge and glycosylation state of mDPP4. We show that glycosylation is a major factor impacting DPP4 receptor function. These results provide insight into DPP4 species-specific differences impacting MERS-CoV host range and may inform MERS-CoV mouse model development. </AbstractText>
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<ReferenceList><Reference><Citation>J Virol. 2014 Feb;88(3):1834-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24257613</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2013 Nov;19(11):1819-23</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24206838</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 May;88(9):4953-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24554656</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 May;88(9):5195-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24574399</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 Aug;88(16):9220-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24899185</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2001 Oct;75(20):9741-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11559807</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Bioinformatics. 2008;9:40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18215316</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2013 Mar 14;495(7440):251-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23486063</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2013 Mar;19(3):456-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23622767</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2013;8(7):e69127</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23844250</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Res. 2013 Aug;23(8):986-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23835475</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2013 Aug 8;500(7461):227-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23831647</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2013;10:266</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23978242</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16157-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24043791</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2014 Feb;95(Pt 2):408-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24197535</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
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<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Caroline du Nord</li>
</region>
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<tree><country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Peck, Kayla M" sort="Peck, Kayla M" uniqKey="Peck K" first="Kayla M" last="Peck">Kayla M. Peck</name>
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<name sortKey="Baric, Ralph S" sort="Baric, Ralph S" uniqKey="Baric R" first="Ralph S" last="Baric">Ralph S. Baric</name>
<name sortKey="Cockrell, Adam S" sort="Cockrell, Adam S" uniqKey="Cockrell A" first="Adam S" last="Cockrell">Adam S. Cockrell</name>
<name sortKey="Heise, Mark T" sort="Heise, Mark T" uniqKey="Heise M" first="Mark T" last="Heise">Mark T. Heise</name>
<name sortKey="Scobey, Trevor" sort="Scobey, Trevor" uniqKey="Scobey T" first="Trevor" last="Scobey">Trevor Scobey</name>
<name sortKey="Yount, Boyd L" sort="Yount, Boyd L" uniqKey="Yount B" first="Boyd L" last="Yount">Boyd L. Yount</name>
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{{Explor lien
   |wiki=    Sante
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   |clé=     pubmed:25653445
   |texte=   Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.
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Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

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