Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations
Identifieur interne : 000C83 ( Ncbi/Merge ); précédent : 000C82; suivant : 000C84Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations
Auteurs : Ahmed S. Abdel-Moneim [Arabie saoudite, Égypte]Source :
- Archives of Virology [ 0304-8608 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Infections à coronavirus.
- génétique : Coronavirus.
- traitement médicamenteux : Infections à coronavirus.
- virologie : Infections à coronavirus.
- Animaux, Coronavirus, Génome viral, Humains, Moyen Orient, Phylogénie, Régulation de l'expression des gènes viraux.
English descriptors
- KwdEn :
- MESH :
- geographic : Middle East.
- classification : Coronavirus.
- diagnosis : Coronavirus Infections.
- drug therapy : Coronavirus Infections.
- genetics : Coronavirus.
- virology : Coronavirus Infections.
- Animals, Gene Expression Regulation, Viral, Genome, Viral, Humans, Phylogeny.
Abstract
In 2012, a novel human coronavirus emerged and was tentatively named “Middle East respiratory syndrome coronavirus” (MERS-CoV). The high mortality rate of MERS-CoV focused attention on the ecology of the virus. It has been found that MERS-CoV belongs to the group C lineage of the genus
Url:
DOI: 10.1007/s00705-014-1995-5
PubMed: 24515532
PubMed Central: 7086939
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Links to Exploration step
PMC:7086939Le document en format XML
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Abdel-Moneim</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.412895.3</institution-id><institution-id institution-id-type="ISNI">0000000404195255</institution-id><institution>Microbiology Department, Virology Division, College of Medicine,</institution><institution>Taif University,</institution></institution-wrap>Al-Taif, 21944 Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Al-Taif</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.411662.6</institution-id><institution-id institution-id-type="ISNI">0000000404124932</institution-id><institution>Virology Department, Faculty of Veterinary Medicine,</institution><institution>Beni-Suef University,</institution></institution-wrap>Beni Suef, 62511 Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Beni Suef</wicri:regionArea></affiliation></author></analytic><series><title level="j">Archives of Virology</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Coronavirus (classification)</term><term>Coronavirus (genetics)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (virology)</term><term>Gene Expression Regulation, Viral</term><term>Genome, Viral</term><term>Humans</term><term>Middle East</term><term>Phylogeny</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Coronavirus ()</term><term>Coronavirus (génétique)</term><term>Génome viral</term><term>Humains</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Infections à coronavirus (virologie)</term><term>Moyen Orient</term><term>Phylogénie</term><term>Régulation de l'expression des gènes viraux</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Middle East</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Gene Expression Regulation, Viral</term><term>Genome, Viral</term><term>Humans</term><term>Phylogeny</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Coronavirus</term><term>Génome viral</term><term>Humains</term><term>Moyen Orient</term><term>Phylogénie</term><term>Régulation de l'expression des gènes viraux</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In 2012, a novel human coronavirus emerged and was tentatively named “Middle East respiratory syndrome coronavirus” (MERS-CoV). The high mortality rate of MERS-CoV focused attention on the ecology of the virus. It has been found that MERS-CoV belongs to the group C lineage of the genus <italic>Betacoronavirus</italic>. Coronavirus surveillance studies in different populations of bats have suggested that they are probable reservoirs for this novel virus, and phylogenetic analysis of both the spike (S1) and RNA-dependent RNA polymerase proteins of MERS-CoV have revealed that it is related to bat viruses. Recently, the MERS-CoV and its neutralizing antibodies were detected in dromedary camels. Despite the limited number of reported cases of person-to-person transmission, the rapid evolution of the virus poses a continuous threat to humans worldwide. 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pmid="24515532"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations</title><author><name sortKey="Abdel Moneim, Ahmed S" sort="Abdel Moneim, Ahmed S" uniqKey="Abdel Moneim A" first="Ahmed S." last="Abdel-Moneim">Ahmed S. Abdel-Moneim</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.412895.3</institution-id><institution-id institution-id-type="ISNI">0000000404195255</institution-id><institution>Microbiology Department, Virology Division, College of Medicine,</institution><institution>Taif University,</institution></institution-wrap>Al-Taif, 21944 Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Al-Taif</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.411662.6</institution-id><institution-id institution-id-type="ISNI">0000000404124932</institution-id><institution>Virology Department, Faculty of Veterinary Medicine,</institution><institution>Beni-Suef University,</institution></institution-wrap>Beni Suef, 62511 Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Beni Suef</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24515532</idno><idno type="pmc">7086939</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086939</idno><idno type="RBID">PMC:7086939</idno><idno type="doi">10.1007/s00705-014-1995-5</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000498</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000498</idno><idno type="wicri:Area/Pmc/Curation">000498</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000498</idno><idno type="wicri:Area/Pmc/Checkpoint">001015</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001015</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations</title><author><name sortKey="Abdel Moneim, Ahmed S" sort="Abdel Moneim, Ahmed S" uniqKey="Abdel Moneim A" first="Ahmed S." last="Abdel-Moneim">Ahmed S. Abdel-Moneim</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.412895.3</institution-id><institution-id institution-id-type="ISNI">0000000404195255</institution-id><institution>Microbiology Department, Virology Division, College of Medicine,</institution><institution>Taif University,</institution></institution-wrap>Al-Taif, 21944 Saudi Arabia</nlm:aff><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Al-Taif</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.411662.6</institution-id><institution-id institution-id-type="ISNI">0000000404124932</institution-id><institution>Virology Department, Faculty of Veterinary Medicine,</institution><institution>Beni-Suef University,</institution></institution-wrap>Beni Suef, 62511 Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Beni Suef</wicri:regionArea></affiliation></author></analytic><series><title level="j">Archives of Virology</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In 2012, a novel human coronavirus emerged and was tentatively named “Middle East respiratory syndrome coronavirus” (MERS-CoV). The high mortality rate of MERS-CoV focused attention on the ecology of the virus. It has been found that MERS-CoV belongs to the group C lineage of the genus <italic>Betacoronavirus</italic>. Coronavirus surveillance studies in different populations of bats have suggested that they are probable reservoirs for this novel virus, and phylogenetic analysis of both the spike (S1) and RNA-dependent RNA polymerase proteins of MERS-CoV have revealed that it is related to bat viruses. Recently, the MERS-CoV and its neutralizing antibodies were detected in dromedary camels. Despite the limited number of reported cases of person-to-person transmission, the rapid evolution of the virus poses a continuous threat to humans worldwide. 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xml:lang="en">Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations.</title><author><name sortKey="Abdel Moneim, Ahmed S" sort="Abdel Moneim, Ahmed S" uniqKey="Abdel Moneim A" first="Ahmed S" last="Abdel-Moneim">Ahmed S. Abdel-Moneim</name><affiliation wicri:level="1"><nlm:affiliation>Microbiology Department, Virology Division, College of Medicine, Taif University, Al-Taif, 21944, Saudi Arabia, asa@tu.edu.sa.</nlm:affiliation><country wicri:rule="url">Arabie saoudite</country><wicri:regionArea>Microbiology Department, Virology Division, College of Medicine, Taif University, Al-Taif, 21944, Saudi Arabia</wicri:regionArea><wicri:noRegion>Saudi Arabia</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24515532</idno><idno type="pmid">24515532</idno><idno type="doi">10.1007/s00705-014-1995-5</idno><idno type="wicri:Area/PubMed/Corpus">001A60</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001A60</idno><idno type="wicri:Area/PubMed/Curation">001A60</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001A60</idno><idno type="wicri:Area/PubMed/Checkpoint">001817</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001817</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations.</title><author><name sortKey="Abdel Moneim, Ahmed S" sort="Abdel Moneim, Ahmed S" uniqKey="Abdel Moneim A" first="Ahmed S" last="Abdel-Moneim">Ahmed S. Abdel-Moneim</name><affiliation wicri:level="1"><nlm:affiliation>Microbiology Department, Virology Division, College of Medicine, Taif University, Al-Taif, 21944, Saudi Arabia, asa@tu.edu.sa.</nlm:affiliation><country wicri:rule="url">Arabie saoudite</country><wicri:regionArea>Microbiology Department, Virology Division, College of Medicine, Taif University, Al-Taif, 21944, Saudi Arabia</wicri:regionArea><wicri:noRegion>Saudi Arabia</wicri:noRegion></affiliation></author></analytic><series><title level="j">Archives of virology</title><idno type="eISSN">1432-8798</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Coronavirus (classification)</term><term>Coronavirus (genetics)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (virology)</term><term>Gene Expression Regulation, Viral</term><term>Genome, Viral</term><term>Humans</term><term>Middle East</term><term>Phylogeny</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Coronavirus ()</term><term>Coronavirus (génétique)</term><term>Génome viral</term><term>Humains</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Infections à coronavirus (virologie)</term><term>Moyen Orient</term><term>Phylogénie</term><term>Régulation de l'expression des gènes viraux</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Middle East</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Gene Expression Regulation, Viral</term><term>Genome, Viral</term><term>Humans</term><term>Phylogeny</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Coronavirus</term><term>Génome viral</term><term>Humains</term><term>Moyen Orient</term><term>Phylogénie</term><term>Régulation de l'expression des gènes viraux</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In 2012, a novel human coronavirus emerged and was tentatively named "Middle East respiratory syndrome coronavirus" (MERS-CoV). The high mortality rate of MERS-CoV focused attention on the ecology of the virus. It has been found that MERS-CoV belongs to the group C lineage of the genus Betacoronavirus. Coronavirus surveillance studies in different populations of bats have suggested that they are probable reservoirs for this novel virus, and phylogenetic analysis of both the spike (S1) and RNA-dependent RNA polymerase proteins of MERS-CoV have revealed that it is related to bat viruses. Recently, the MERS-CoV and its neutralizing antibodies were detected in dromedary camels. Despite the limited number of reported cases of person-to-person transmission, the rapid evolution of the virus poses a continuous threat to humans worldwide. This paper reviews the current state of knowledge regarding the virology, clinical spectrum, evolution, diagnosis and treatment of MERS-CoV infections.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
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