[Bats, viruses and humans: coronaviruses on the rise?].
Identifieur interne : 000C81 ( Ncbi/Merge ); précédent : 000C80; suivant : 000C82[Bats, viruses and humans: coronaviruses on the rise?].
Auteurs : Christine Winter [Allemagne] ; Georg HerrlerSource :
- Berliner und Munchener tierarztliche Wochenschrift [ 0005-9366 ]
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Glycoprotéine de spicule des coronavirus.
- physiologie : Coronaviridae.
- virologie : Chiroptera, Réservoirs d'agents pathogènes.
- épidémiologie : Infections à Coronaviridae.
- Animaux, Humains.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Spike Glycoprotein, Coronavirus.
- epidemiology : Coronaviridae Infections.
- physiology : Coronaviridae.
- transmission : Coronaviridae Infections.
- virology : Chiroptera, Disease Reservoirs.
- Animals, Humans.
Abstract
The outbreak of the SARS coronavirus in 2002/2003 and the recent disease cases with a new human coronavirus (originally designated EMC-CoV, recently renamed MERS-CoV) have put the focus onto the virus family Coronaviridae. Both viruses appeared to have managed to jump over the species barrier from a bat reservoir to the human population. Bats are considered to serve as a natural reservoir for coronaviruses infecting mammals. An important factor for crossing the species-barrier is the adaptation to a new receptor on cells of the new host species. During evolution coronaviruses have developed a large diversity of binding specificities demonstrating the high flexibility of the coronaviral spike protein, which is responsible for binding to target cells.
PubMed: 24511826
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pubmed:24511826Le document en format XML
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Both viruses appeared to have managed to jump over the species barrier from a bat reservoir to the human population. Bats are considered to serve as a natural reservoir for coronaviruses infecting mammals. An important factor for crossing the species-barrier is the adaptation to a new receptor on cells of the new host species. During evolution coronaviruses have developed a large diversity of binding specificities demonstrating the high flexibility of the coronaviral spike protein, which is responsible for binding to target cells.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24511826</PMID><DateCompleted><Year>2015</Year><Month>04</Month><Day>09</Day></DateCompleted><DateRevised><Year>2014</Year><Month>02</Month><Day>11</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0005-9366</ISSN><JournalIssue CitedMedium="Print"><Volume>126</Volume><Issue>11-12</Issue><PubDate><MedlineDate>2013 Nov-Dec</MedlineDate></PubDate></JournalIssue><Title>Berliner und Munchener tierarztliche Wochenschrift</Title><ISOAbbreviation>Berl. Munch. Tierarztl. Wochenschr.</ISOAbbreviation></Journal><ArticleTitle>[Bats, viruses and humans: coronaviruses on the rise?].</ArticleTitle><Pagination><MedlinePgn>509-13</MedlinePgn></Pagination><Abstract><AbstractText>The outbreak of the SARS coronavirus in 2002/2003 and the recent disease cases with a new human coronavirus (originally designated EMC-CoV, recently renamed MERS-CoV) have put the focus onto the virus family Coronaviridae. Both viruses appeared to have managed to jump over the species barrier from a bat reservoir to the human population. Bats are considered to serve as a natural reservoir for coronaviruses infecting mammals. An important factor for crossing the species-barrier is the adaptation to a new receptor on cells of the new host species. 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