Inactivated RNA polymerase II open complexes can be reactivated with TFIIE.
Identifieur interne : 000903 ( Ncbi/Merge ); précédent : 000902; suivant : 000904Inactivated RNA polymerase II open complexes can be reactivated with TFIIE.
Auteurs : Pavel Abart [États-Unis] ; Donal S. LuseSource :
- The Journal of biological chemistry [ 1083-351X ] ; 2012.
Descripteurs français
- KwdFr :
- Adénosine triphosphate (), Adénosine triphosphate (génétique), Adénosine triphosphate (métabolisme), Cellules HeLa, Facteur de transcription TFIIH (), Facteur de transcription TFIIH (génétique), Facteur de transcription TFIIH (métabolisme), Facteurs de transcription TFII (), Facteurs de transcription TFII (génétique), Facteurs de transcription TFII (métabolisme), Humains, RNA polymerase II (), RNA polymerase II (génétique), RNA polymerase II (métabolisme), Transcription génétique (physiologie).
- MESH :
- génétique : Adénosine triphosphate, Facteur de transcription TFIIH, Facteurs de transcription TFII, RNA polymerase II.
- métabolisme : Adénosine triphosphate, Facteur de transcription TFIIH, Facteurs de transcription TFII, RNA polymerase II.
- physiologie : Transcription génétique.
- Adénosine triphosphate, Cellules HeLa, Facteur de transcription TFIIH, Facteurs de transcription TFII, Humains, RNA polymerase II.
English descriptors
- KwdEn :
- Adenosine Triphosphate (chemistry), Adenosine Triphosphate (genetics), Adenosine Triphosphate (metabolism), HeLa Cells, Humans, RNA Polymerase II (chemistry), RNA Polymerase II (genetics), RNA Polymerase II (metabolism), Transcription Factor TFIIH (chemistry), Transcription Factor TFIIH (genetics), Transcription Factor TFIIH (metabolism), Transcription Factors, TFII (chemistry), Transcription Factors, TFII (genetics), Transcription Factors, TFII (metabolism), Transcription, Genetic (physiology).
- MESH :
- chemical , chemistry : Adenosine Triphosphate, RNA Polymerase II, Transcription Factor TFIIH, Transcription Factors, TFII.
- chemical , genetics : Adenosine Triphosphate, RNA Polymerase II, Transcription Factor TFIIH, Transcription Factors, TFII.
- chemical , metabolism : Adenosine Triphosphate, RNA Polymerase II, Transcription Factor TFIIH, Transcription Factors, TFII.
- physiology : Transcription, Genetic.
- HeLa Cells, Humans.
Abstract
Transcript initiation by RNA polymerase II (pol II) requires a helicase within TFIIH to generate the unpaired template strand. However, pol II preinitiation complexes (PICs) lose the ability to synthesize RNA very rapidly upon exposure to ATP alone in the absence of other NTPs. This inactivation is not caused by the TFIIH kinase activity, the loss of transcription factors or pol II from the PIC, or the collapse of the initially formed transcription bubble. TFIIE is necessary for PIC formation, but TFIIE is not retained as a stable component in PICs prepared by our protocol. Nevertheless, activity can be at least partially restored to ATP-treated PICs by the readdition of TFIIE. PICs formed on premelted (bubble) templates require TFIIH for effective transcript elongation to +20. Incubation of bubble template PICs with ATP caused reduced yields of 20-mers, but this effect was partially reversed by the addition of TFIIE. Our results suggest that once the open complex is formed, TFIIH decays into an inactive configuration in the absence of nucleotides for transcription. Although TFIIE does not play a role in transcript initiation itself, inactivation resulting from ATP preincubation can be reversed by a remodeling process mediated by TFIIE. Finally, we have also uncovered a major role for TFIIF in the earliest stages of transcript elongation that is unique to bubble templates.
DOI: 10.1074/jbc.M111.297572
PubMed: 22119917
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001E33
- to stream PubMed, to step Curation: 001E33
- to stream PubMed, to step Checkpoint: 001C74
Links to Exploration step
pubmed:22119917Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Inactivated RNA polymerase II open complexes can be reactivated with TFIIE.</title>
<author><name sortKey=" Abart, Pavel" sort=" Abart, Pavel" uniqKey=" Abart P" first="Pavel" last=" Abart">Pavel Abart</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195</wicri:regionArea>
<wicri:noRegion>Ohio 44195</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Luse, Donal S" sort="Luse, Donal S" uniqKey="Luse D" first="Donal S" last="Luse">Donal S. Luse</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2012">2012</date>
<idno type="RBID">pubmed:22119917</idno>
<idno type="pmid">22119917</idno>
<idno type="doi">10.1074/jbc.M111.297572</idno>
<idno type="wicri:Area/PubMed/Corpus">001E33</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001E33</idno>
<idno type="wicri:Area/PubMed/Curation">001E33</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001E33</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001C74</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001C74</idno>
<idno type="wicri:Area/Ncbi/Merge">000903</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Inactivated RNA polymerase II open complexes can be reactivated with TFIIE.</title>
<author><name sortKey=" Abart, Pavel" sort=" Abart, Pavel" uniqKey=" Abart P" first="Pavel" last=" Abart">Pavel Abart</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195</wicri:regionArea>
<wicri:noRegion>Ohio 44195</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Luse, Donal S" sort="Luse, Donal S" uniqKey="Luse D" first="Donal S" last="Luse">Donal S. Luse</name>
</author>
</analytic>
<series><title level="j">The Journal of biological chemistry</title>
<idno type="eISSN">1083-351X</idno>
<imprint><date when="2012" type="published">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenosine Triphosphate (chemistry)</term>
<term>Adenosine Triphosphate (genetics)</term>
<term>Adenosine Triphosphate (metabolism)</term>
<term>HeLa Cells</term>
<term>Humans</term>
<term>RNA Polymerase II (chemistry)</term>
<term>RNA Polymerase II (genetics)</term>
<term>RNA Polymerase II (metabolism)</term>
<term>Transcription Factor TFIIH (chemistry)</term>
<term>Transcription Factor TFIIH (genetics)</term>
<term>Transcription Factor TFIIH (metabolism)</term>
<term>Transcription Factors, TFII (chemistry)</term>
<term>Transcription Factors, TFII (genetics)</term>
<term>Transcription Factors, TFII (metabolism)</term>
<term>Transcription, Genetic (physiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adénosine triphosphate ()</term>
<term>Adénosine triphosphate (génétique)</term>
<term>Adénosine triphosphate (métabolisme)</term>
<term>Cellules HeLa</term>
<term>Facteur de transcription TFIIH ()</term>
<term>Facteur de transcription TFIIH (génétique)</term>
<term>Facteur de transcription TFIIH (métabolisme)</term>
<term>Facteurs de transcription TFII ()</term>
<term>Facteurs de transcription TFII (génétique)</term>
<term>Facteurs de transcription TFII (métabolisme)</term>
<term>Humains</term>
<term>RNA polymerase II ()</term>
<term>RNA polymerase II (génétique)</term>
<term>RNA polymerase II (métabolisme)</term>
<term>Transcription génétique (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Adenosine Triphosphate</term>
<term>RNA Polymerase II</term>
<term>Transcription Factor TFIIH</term>
<term>Transcription Factors, TFII</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Adenosine Triphosphate</term>
<term>RNA Polymerase II</term>
<term>Transcription Factor TFIIH</term>
<term>Transcription Factors, TFII</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Adenosine Triphosphate</term>
<term>RNA Polymerase II</term>
<term>Transcription Factor TFIIH</term>
<term>Transcription Factors, TFII</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Adénosine triphosphate</term>
<term>Facteur de transcription TFIIH</term>
<term>Facteurs de transcription TFII</term>
<term>RNA polymerase II</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Adénosine triphosphate</term>
<term>Facteur de transcription TFIIH</term>
<term>Facteurs de transcription TFII</term>
<term>RNA polymerase II</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Transcription génétique</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Transcription, Genetic</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>HeLa Cells</term>
<term>Humans</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adénosine triphosphate</term>
<term>Cellules HeLa</term>
<term>Facteur de transcription TFIIH</term>
<term>Facteurs de transcription TFII</term>
<term>Humains</term>
<term>RNA polymerase II</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Transcript initiation by RNA polymerase II (pol II) requires a helicase within TFIIH to generate the unpaired template strand. However, pol II preinitiation complexes (PICs) lose the ability to synthesize RNA very rapidly upon exposure to ATP alone in the absence of other NTPs. This inactivation is not caused by the TFIIH kinase activity, the loss of transcription factors or pol II from the PIC, or the collapse of the initially formed transcription bubble. TFIIE is necessary for PIC formation, but TFIIE is not retained as a stable component in PICs prepared by our protocol. Nevertheless, activity can be at least partially restored to ATP-treated PICs by the readdition of TFIIE. PICs formed on premelted (bubble) templates require TFIIH for effective transcript elongation to +20. Incubation of bubble template PICs with ATP caused reduced yields of 20-mers, but this effect was partially reversed by the addition of TFIIE. Our results suggest that once the open complex is formed, TFIIH decays into an inactive configuration in the absence of nucleotides for transcription. Although TFIIE does not play a role in transcript initiation itself, inactivation resulting from ATP preincubation can be reversed by a remodeling process mediated by TFIIE. Finally, we have also uncovered a major role for TFIIF in the earliest stages of transcript elongation that is unique to bubble templates.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22119917</PMID>
<DateCompleted><Year>2012</Year>
<Month>02</Month>
<Day>27</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1083-351X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>287</Volume>
<Issue>2</Issue>
<PubDate><Year>2012</Year>
<Month>Jan</Month>
<Day>06</Day>
</PubDate>
</JournalIssue>
<Title>The Journal of biological chemistry</Title>
<ISOAbbreviation>J. Biol. Chem.</ISOAbbreviation>
</Journal>
<ArticleTitle>Inactivated RNA polymerase II open complexes can be reactivated with TFIIE.</ArticleTitle>
<Pagination><MedlinePgn>961-7</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1074/jbc.M111.297572</ELocationID>
<Abstract><AbstractText>Transcript initiation by RNA polymerase II (pol II) requires a helicase within TFIIH to generate the unpaired template strand. However, pol II preinitiation complexes (PICs) lose the ability to synthesize RNA very rapidly upon exposure to ATP alone in the absence of other NTPs. This inactivation is not caused by the TFIIH kinase activity, the loss of transcription factors or pol II from the PIC, or the collapse of the initially formed transcription bubble. TFIIE is necessary for PIC formation, but TFIIE is not retained as a stable component in PICs prepared by our protocol. Nevertheless, activity can be at least partially restored to ATP-treated PICs by the readdition of TFIIE. PICs formed on premelted (bubble) templates require TFIIH for effective transcript elongation to +20. Incubation of bubble template PICs with ATP caused reduced yields of 20-mers, but this effect was partially reversed by the addition of TFIIE. Our results suggest that once the open complex is formed, TFIIH decays into an inactive configuration in the absence of nucleotides for transcription. Although TFIIE does not play a role in transcript initiation itself, inactivation resulting from ATP preincubation can be reversed by a remodeling process mediated by TFIIE. Finally, we have also uncovered a major role for TFIIF in the earliest stages of transcript elongation that is unique to bubble templates.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Čabart</LastName>
<ForeName>Pavel</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Luse</LastName>
<ForeName>Donal S</ForeName>
<Initials>DS</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>R01 GM029487</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>GM 29487</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2011</Year>
<Month>11</Month>
<Day>27</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Biol Chem</MedlineTA>
<NlmUniqueID>2985121R</NlmUniqueID>
<ISSNLinking>0021-9258</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D019473">Transcription Factors, TFII</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C066644">transcription factor TFIIE</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>148710-81-0</RegistryNumber>
<NameOfSubstance UI="D051758">Transcription Factor TFIIH</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>8L70Q75FXE</RegistryNumber>
<NameOfSubstance UI="D000255">Adenosine Triphosphate</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.7.-</RegistryNumber>
<NameOfSubstance UI="D012319">RNA Polymerase II</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000255" MajorTopicYN="N">Adenosine Triphosphate</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006367" MajorTopicYN="N">HeLa Cells</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012319" MajorTopicYN="N">RNA Polymerase II</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051758" MajorTopicYN="N">Transcription Factor TFIIH</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019473" MajorTopicYN="N">Transcription Factors, TFII</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014158" MajorTopicYN="N">Transcription, Genetic</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year>
<Month>11</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2011</Year>
<Month>11</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2012</Year>
<Month>3</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">22119917</ArticleId>
<ArticleId IdType="pii">M111.297572</ArticleId>
<ArticleId IdType="doi">10.1074/jbc.M111.297572</ArticleId>
<ArticleId IdType="pmc">PMC3256861</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Mol Cell. 1999 Jan;3(1):87-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10024882</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15786-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21896726</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1999 Aug 6;274(32):22127-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10428772</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1999 Dec 10;274(50):35668-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10585446</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2000 Jan 28;275(4):2532-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10644710</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2000 May 26;288(5470):1418-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10827951</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2001 Feb 9;104(3):353-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11239393</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Cells. 2003 Jan;8(1):41-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12558798</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2003 Mar 21;278(12):10250-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12527757</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2003 May 13;100(10):5700-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12719526</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 2004 Feb;24(3):1122-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14729958</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Struct Mol Biol. 2004 May;11(5):394-403</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15114340</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1987 Jan 5;262(1):289-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2432060</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 1993 Apr 2;260(5104):58-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8465201</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 1993 May 7;73(3):533-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8490964</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1993 Aug 15;268(23):17300-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8394338</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 1994 Feb 11;263(5148):805-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8303296</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1994 Jan 15;13(2):391-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8313884</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1994 Jul 15;269(28):18414-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8034589</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1994 Mar 1;8(5):515-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7926747</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1994 Dec 2;269(48):30101-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7982911</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1995 Feb 15;14(4):810-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7882984</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 1995 Sep;15(9):4856-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7651404</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1996 Mar 29;271(13):7245-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8631733</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1996 Aug 16;271(33):20170-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8702741</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods Enzymol. 1996;274:72-100</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8902797</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1997 Jun 20;272(25):15936-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9188494</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1997 Dec 15;16(24):7457-67</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9405374</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1997 Dec 15;16(24):7468-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9405375</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell. 2005 Jul 1;19(1):101-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15989968</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Struct Mol Biol. 2006 Jan;13(1):49-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16327806</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Struct Mol Biol. 2006 Jul;13(7):603-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16819517</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 2006 Aug 15;20(16):2250-65</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16912275</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Struct Mol Biol. 2007 Aug;14(8):696-703</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17632521</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):106-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18160537</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 2008 Jun;28(11):3757-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18362165</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Cell Biol. 2008 Jun;20(3):253-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18436437</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):546-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21187417</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 2011 Apr 6;30(7):1302-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21386817</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2011 Jul 1;286(26):23160-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21566144</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell. 2011 Jul 22;43(2):263-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21777815</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1999 Mar 1;18(5):1357-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10064601</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>États-Unis</li>
</country>
</list>
<tree><noCountry><name sortKey="Luse, Donal S" sort="Luse, Donal S" uniqKey="Luse D" first="Donal S" last="Luse">Donal S. Luse</name>
</noCountry>
<country name="États-Unis"><noRegion><name sortKey=" Abart, Pavel" sort=" Abart, Pavel" uniqKey=" Abart P" first="Pavel" last=" Abart">Pavel Abart</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000903 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000903 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Ncbi |étape= Merge |type= RBID |clé= pubmed:22119917 |texte= Inactivated RNA polymerase II open complexes can be reactivated with TFIIE. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:22119917" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |